Andres E Leschziner

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Visualizing flexibility at molecular resolution: analysis of heterogeneity in single-particle electron microscopy reconstructions
    Andres E Leschziner
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Annu Rev Biophys Biomol Struct 36:43-62. 2007
  2. pmc Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method
    Andres E Leschziner
    Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 104:4913-8. 2007
  3. ncbi Structural studies of the human PBAF chromatin-remodeling complex
    Andres E Leschziner
    Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Structure 13:267-75. 2005
  4. ncbi The orthogonal tilt reconstruction method: an approach to generating single-class volumes with no missing cone for ab initio reconstruction of asymmetric particles
    Andres E Leschziner
    Lawrence Berkeley National Laboratory, University of California, Berkeley, USA
    J Struct Biol 153:284-99. 2006
  5. ncbi Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex
    Megan G Clarey
    Division of Biochemistry and Molecular Biology, Molecular and Cell Biology Department, 1 Barker Hall, University of California, Berkeley, California 94720, USA
    Nat Struct Mol Biol 13:684-90. 2006
  6. ncbi Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms
    Hong Wei Wang
    Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, California 94720, USA
    Nat Struct Mol Biol 14:721-6. 2007

Collaborators

Detail Information

Publications6

  1. ncbi Visualizing flexibility at molecular resolution: analysis of heterogeneity in single-particle electron microscopy reconstructions
    Andres E Leschziner
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Annu Rev Biophys Biomol Struct 36:43-62. 2007
    ..We also discuss some of their recent applications to problems of biological interest...
  2. pmc Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method
    Andres E Leschziner
    Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 104:4913-8. 2007
    ..We present a model of the RSC-nucleosome complex that rationalizes the single molecule results obtained by using optical tweezers and also discuss the mechanistic implications of our structures...
  3. ncbi Structural studies of the human PBAF chromatin-remodeling complex
    Andres E Leschziner
    Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Structure 13:267-75. 2005
    ..The 2D analysis of PBAF:nucleosome complexes indicates that the nucleosome binds in the central cavity...
  4. ncbi The orthogonal tilt reconstruction method: an approach to generating single-class volumes with no missing cone for ab initio reconstruction of asymmetric particles
    Andres E Leschziner
    Lawrence Berkeley National Laboratory, University of California, Berkeley, USA
    J Struct Biol 153:284-99. 2006
    ..We also propose a way of increasing the level of homogeneity in individual 2D classes (and volumes) in a heterogeneous data set and identifying the most homogeneous volumes...
  5. ncbi Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex
    Megan G Clarey
    Division of Biochemistry and Molecular Biology, Molecular and Cell Biology Department, 1 Barker Hall, University of California, Berkeley, California 94720, USA
    Nat Struct Mol Biol 13:684-90. 2006
    ..By analogy to the DNA-wrapping activity of DnaA, we posit that ORC together with Cdc6 prepares origin DNA for helicase loading through mechanisms related to the established pathway of prokaryotes...
  6. ncbi Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms
    Hong Wei Wang
    Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, California 94720, USA
    Nat Struct Mol Biol 14:721-6. 2007
    ..One of Ipl1's roles might be to fine-tune the coupling of the microtubule interaction with the conformational change required for oligomerization, with phosphorylation resulting in ring breakdown...