Eric J Lepin

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors
    Eric J Lepin
    Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Eur J Nucl Med Mol Imaging 37:1529-38. 2010
  2. pmc Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines
    Kaori Shimazaki
    Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA
    Clin Cancer Res 14:7367-77. 2008
  3. pmc Humanized radioiodinated minibody for imaging of prostate stem cell antigen-expressing tumors
    Jeffrey V Leyton
    Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA
    Clin Cancer Res 14:7488-96. 2008
  4. doi A differential cell capture assay for evaluating antibody interactions with cell surface targets
    David J Sherman
    Department of Molecular and Medical Pharmacology, Crump Institute of Molecular Imaging, California NanoSystems Institute, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Anal Biochem 401:173-81. 2010
  5. pmc Cys-diabody quantum dot conjugates (immunoQdots) for cancer marker detection
    Bhaswati Barat
    Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Bioconjug Chem 20:1474-81. 2009

Collaborators

  • Anna M Wu
  • Tove Olafsen
  • James D Marks
  • Madhuri Wadehra
  • Shannon J Sirk
  • Ken ichiro Kamei
  • David J Sherman
  • Katelyn E McCabe
  • Bhaswati Barat
  • Kaori Shimazaki
  • Jeffrey V Leyton
  • Hsian Rong Tseng
  • Christian P Behrenbruch
  • Shutao Wang
  • Minori Ohashi
  • Vania E Kenanova
  • Jianqing Li
  • Sanjiv S Gambhir
  • Roland Remenyi
  • Shimon Weiss
  • Ai Leen Koh
  • Sergey Mareninov
  • Lynn K Gordon
  • Scott Hahm
  • Bo Wei
  • Robert E Reiter
  • Maoyong Fu
  • Karl B Bauer
  • Catherine P Coulam
  • Jonathan Braun
  • Agnes K Nagy

Detail Information

Publications5

  1. pmc An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors
    Eric J Lepin
    Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Eur J Nucl Med Mol Imaging 37:1529-38. 2010
    ..However, the humanization and antibody fragment reformatting decreased its apparent affinity. Here, we sought to evaluate PET imaging contrast with affinity matured minibodies...
  2. pmc Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines
    Kaori Shimazaki
    Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA
    Clin Cancer Res 14:7367-77. 2008
    ..The present study assesses the suitability of EMP2 as a therapeutic target...
  3. pmc Humanized radioiodinated minibody for imaging of prostate stem cell antigen-expressing tumors
    Jeffrey V Leyton
    Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA
    Clin Cancer Res 14:7488-96. 2008
    ..In this study, the 2B3 minibody (an 80-kDa engineered antibody fragment) has been produced for rapid targeting and imaging...
  4. doi A differential cell capture assay for evaluating antibody interactions with cell surface targets
    David J Sherman
    Department of Molecular and Medical Pharmacology, Crump Institute of Molecular Imaging, California NanoSystems Institute, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Anal Biochem 401:173-81. 2010
    ..This approach can find utility when an antibody or antibody fragment against a known cell line needs to be selected for targeting studies...
  5. pmc Cys-diabody quantum dot conjugates (immunoQdots) for cancer marker detection
    Bhaswati Barat
    Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Bioconjug Chem 20:1474-81. 2009
    ....