Eric J Lenze

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Somatic symptoms in late-life anxiety: treatment issues
    Eric J Lenze
    Intervention Research Center for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    J Geriatr Psychiatry Neurol 18:89-96. 2005
  2. ncbi request reprint Generalized anxiety disorder in late life: lifetime course and comorbidity with major depressive disorder
    Eric J Lenze
    Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Am J Geriatr Psychiatry 13:77-80. 2005
  3. ncbi request reprint Onset of depression in elderly persons after hip fracture: implications for prevention and early intervention of late-life depression
    Eric J Lenze
    Advanced Center for Interventions and Services Research and John A Hartford Center of Excellence in Geriatric Psychiatry, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    J Am Geriatr Soc 55:81-6. 2007
  4. pmc Does depression, apathy or cognitive impairment reduce the benefit of inpatient rehabilitation facilities for elderly hip fracture patients?
    Eric J Lenze
    Department of Psychiatry, University of Pittsburgh School of Medicine, Advanced Center for Interventions and Services Research in Late Life Mood Disorders and John A Hartford Center of Excellence in Geriatric Psychiatry, PA 15213, USA
    Gen Hosp Psychiatry 29:141-6. 2007
  5. ncbi request reprint The course of functional decline in older people with persistently elevated depressive symptoms: longitudinal findings from the Cardiovascular Health Study
    Eric J Lenze
    Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Am Geriatr Soc 53:569-75. 2005
  6. ncbi request reprint Association of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) genotype with depression in elderly persons after hip fracture
    Eric J Lenze
    Intervention Research Center for the Study of Late Life Mood Disorders, Department of Psychiatry, University of Pittsburg School of Medicine, Pittsburgh, PA, USA
    Am J Geriatr Psychiatry 13:428-32. 2005
  7. ncbi request reprint Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy
    Mary Amanda Dew
    Department of Psychiatry, University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Am J Psychiatry 164:892-9. 2007
  8. ncbi request reprint Outcomes of late-life anxiety disorders during 32 weeks of citalopram treatment
    Stephen Blank
    Intervention Research Center for Late Life Mood Disorders, The Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Clin Psychiatry 67:468-72. 2006
  9. ncbi request reprint Effect of comorbid anxiety on treatment response and relapse risk in late-life depression: controlled study
    Carmen Andreescu
    Western Psychiatric Institute and Clinic, 3811 O Hara Street, Room E 823, Pittsburgh, PA15213, USA
    Br J Psychiatry 190:344-9. 2007
  10. ncbi request reprint Good treatment outcomes in late-life depression with comorbid anxiety
    Eric J Lenze
    The Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Affect Disord 77:247-54. 2003

Research Grants

Detail Information

Publications63

  1. ncbi request reprint Somatic symptoms in late-life anxiety: treatment issues
    Eric J Lenze
    Intervention Research Center for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    J Geriatr Psychiatry Neurol 18:89-96. 2005
    ..However, additional treatment and integrated approaches are likely to be necessary for many such individuals...
  2. ncbi request reprint Generalized anxiety disorder in late life: lifetime course and comorbidity with major depressive disorder
    Eric J Lenze
    Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Am J Geriatr Psychiatry 13:77-80. 2005
    ..The authors assessed the course and comorbidity of late-life GAD and MDD...
  3. ncbi request reprint Onset of depression in elderly persons after hip fracture: implications for prevention and early intervention of late-life depression
    Eric J Lenze
    Advanced Center for Interventions and Services Research and John A Hartford Center of Excellence in Geriatric Psychiatry, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    J Am Geriatr Soc 55:81-6. 2007
    ..To identify predictors of onset of major depressive disorder (MDD) and of depressive symptoms in subjects who suffered a hip fracture...
  4. pmc Does depression, apathy or cognitive impairment reduce the benefit of inpatient rehabilitation facilities for elderly hip fracture patients?
    Eric J Lenze
    Department of Psychiatry, University of Pittsburgh School of Medicine, Advanced Center for Interventions and Services Research in Late Life Mood Disorders and John A Hartford Center of Excellence in Geriatric Psychiatry, PA 15213, USA
    Gen Hosp Psychiatry 29:141-6. 2007
    ....
  5. ncbi request reprint The course of functional decline in older people with persistently elevated depressive symptoms: longitudinal findings from the Cardiovascular Health Study
    Eric J Lenze
    Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Am Geriatr Soc 53:569-75. 2005
    ..To examine the relationship between persistently high depressive symptoms and long-term changes in functional disability in elderly persons...
  6. ncbi request reprint Association of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) genotype with depression in elderly persons after hip fracture
    Eric J Lenze
    Intervention Research Center for the Study of Late Life Mood Disorders, Department of Psychiatry, University of Pittsburg School of Medicine, Pittsburgh, PA, USA
    Am J Geriatr Psychiatry 13:428-32. 2005
    ..The authors examined the serotonin transporter gene-linked polymorphic region (5-HTTLPR) as a predictor of major depressive disorder and depressive symptoms after hip fracture, a common stressful medical event...
  7. ncbi request reprint Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy
    Mary Amanda Dew
    Department of Psychiatry, University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Am J Psychiatry 164:892-9. 2007
    ..The authors examined likelihood, speed, and predictors of recovery in older adults receiving augmentation pharmacotherapy after inadequate response to standardized treatment with paroxetine plus interpersonal psychotherapy...
  8. ncbi request reprint Outcomes of late-life anxiety disorders during 32 weeks of citalopram treatment
    Stephen Blank
    Intervention Research Center for Late Life Mood Disorders, The Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Clin Psychiatry 67:468-72. 2006
    ..Anxiety disorders are common in later life, but little is known about the long-term benefits and risks of pharmacotherapy...
  9. ncbi request reprint Effect of comorbid anxiety on treatment response and relapse risk in late-life depression: controlled study
    Carmen Andreescu
    Western Psychiatric Institute and Clinic, 3811 O Hara Street, Room E 823, Pittsburgh, PA15213, USA
    Br J Psychiatry 190:344-9. 2007
    ..Comorbid anxiety is common in depressive disorders in both middle and late life, and it affects response to antidepressant treatment...
  10. ncbi request reprint Good treatment outcomes in late-life depression with comorbid anxiety
    Eric J Lenze
    The Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Affect Disord 77:247-54. 2003
    ..This study evaluated the impact of comorbid anxiety on response, dropouts, and side effects, in elderly subjects treated for depression...
  11. pmc Maintenance treatment of depression in old age: a randomized, double-blind, placebo-controlled evaluation of the efficacy and safety of donepezil combined with antidepressant pharmacotherapy
    Charles F Reynolds
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 68:51-60. 2011
    ..Cognitive impairment in late-life depression is a core feature of the illness...
  12. pmc Pilot study of augmentation with aripiprazole for incomplete response in late-life depression: getting to remission
    Meera Sheffrin
    Advanced Center in Interventions and Services Research for Late Life Mood Disorders ACISR LLMD and the John A Hartford Center of Excellence in Geriatric Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 70:208-13. 2009
    ....
  13. pmc High worry severity is associated with poorer acute and maintenance efficacy of antidepressants in late-life depression
    Carmen Andreescu
    The Advanced Center in Interventions and Services Research for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Depress Anxiety 26:266-72. 2009
    ..We explored the impact of the dimensions of worry and panic on acute and maintenance treatment outcomes in LLD...
  14. ncbi request reprint Impact of prior treatment exposure on response to antidepressant treatment in late life
    James D Tew
    Advanced Center for Interventions and Services Research in Late Life Mood Disorders, Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Geriatr Psychiatry 14:957-65. 2006
    ..The objective of this study was to describe the correlates of prior antidepressant exposure and its association with response to protocolized treatment in older patients with major depression...
  15. ncbi request reprint Efficacy and tolerability of citalopram in the treatment of late-life anxiety disorders: results from an 8-week randomized, placebo-controlled trial
    Eric J Lenze
    Intervention Research Center for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine and VA Healthcare System, PA, USA
    Am J Psychiatry 162:146-50. 2005
    ..Anxiety disorders are highly prevalent in elderly persons. However, to date, the efficacy of selective serotonin reuptake inhibitors (SSRIs) for the treatment of anxiety disorders in this age group has not been established...
  16. pmc Residual symptoms and recurrence during maintenance treatment of late-life depression
    Alexandre Y Dombrovski
    Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, United States
    J Affect Disord 103:77-82. 2007
    ..Our study assesses the impact of these residual symptoms on the risk of recurrence during maintenance treatment of late-life depression...
  17. pmc Elevated cortisol in older adults with generalized anxiety disorder is reduced by treatment: a placebo-controlled evaluation of escitalopram
    Eric J Lenze
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Geriatr Psychiatry 19:482-90. 2011
    ..The authors examined whether treatment of GAD in older adults with a selective serotonin reuptake inhibitor (SSRI) corrects this HPA axis hyperactivity...
  18. pmc Changes in neuropsychological functioning following treatment for late-life generalised anxiety disorder
    Meryl A Butters
    Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Br J Psychiatry 199:211-8. 2011
    ..Aims We examined neuropsychological functioning in older adults with GAD in comparison with psychiatrically healthy older adults at baseline, and we examined changes following a 12-week placebo-controlled trial of escitalopram...
  19. pmc Predicting 6-week treatment response to escitalopram pharmacotherapy in late-life major depressive disorder
    Ramin Saghafi
    Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, USA
    Int J Geriatr Psychiatry 22:1141-6. 2007
    ..This study aims to characterize sociodemographic, clinical, and neuropsychologic correlates of full, partial, and non-response to escitalopram monotherapy of unipolar MDD in later life...
  20. pmc Apathy after hip fracture: a potential target for intervention to improve functional outcomes
    Eric J Lenze
    Department of Psychiatry, Washington University School of Medicine, USA
    J Neuropsychiatry Clin Neurosci 21:271-8. 2009
    ..Interventions to prevent or improve apathy in elderly persons deserve further attention...
  21. ncbi request reprint Risk factors for falls during treatment of late-life depression
    Jin H Joo
    Intervention Research Center for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    J Clin Psychiatry 63:936-41. 2002
    ..This study evaluated the time course and potential risk factors for falls in a treatment protocol for late-life depression to identify specific at-risk periods and risk factors for falls in this population...
  22. pmc An open-label pilot study of acetylcholinesterase inhibitors to promote functional recovery in elderly cognitively impaired stroke patients
    Ellen M Whyte
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Cerebrovasc Dis 26:317-21. 2008
    ..We investigated the feasibility of using acetylcholinesterase inhibitors in older patients with acute post-stroke cognitive impairment and examined their effects on functional recovery...
  23. pmc Incomplete response in late-life depression: getting to remission
    Eric J Lenze
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO, USA
    Dialogues Clin Neurosci 10:419-30. 2008
    ..Such studies may advance us toward the goal of personalized treatment in late-life depression...
  24. doi request reprint Treatment-related alteration of cortisol predicts change in neuropsychological function during acute treatment of late-life anxiety disorder
    Eric J Lenze
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Int J Geriatr Psychiatry 27:454-62. 2012
    ....
  25. ncbi request reprint Cognitive impairment in late-life generalized anxiety disorder
    Rose C Mantella
    Advanced Center in Interventions and Services Research for Late Life Mood Disorders and the John A Hartford Center of Excellence in Geriatric Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Am J Geriatr Psychiatry 15:673-9. 2007
    ..This study sought to characterize cognitive functioning in elderly patients with generalized anxiety disorder (GAD), as compared with normal comparison subjects and patients with major depression...
  26. ncbi request reprint Maintenance treatment for old-age depression preserves health-related quality of life: a randomized, controlled trial of paroxetine and interpersonal psychotherapy
    Alexandre Y Dombrovski
    Western Psychiatric Institute and Clinic, Department of Psychiatry, School of Medicine, University of Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 55:1325-32. 2007
    ..To determine whether maintenance antidepressant pharmacotherapy and interpersonal psychotherapy sustain gains in health-related quality of life (HR-QOL) achieved during short-term treatment in older patients with depression...
  27. ncbi request reprint Comorbid anxiety disorder in late life depression: association with memory decline over four years
    Alison K DeLuca
    The Intervention Research Center for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Int J Geriatr Psychiatry 20:848-54. 2005
    ..The purpose of this study was to determine whether comorbid GAD or PD was associated with poorer long-term outcomes of late-life MDD, in terms of symptoms, functional disability, and cognitive status...
  28. ncbi request reprint Somatic symptoms of depression in elderly patients with medical comorbidities
    Rebecca A Drayer
    Center for Research on Health Care, Division of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Int J Geriatr Psychiatry 20:973-82. 2005
    ..These analyses were designed to determine if somatic symptoms in older patients are more strongly associated with chronic physical problems or with depression...
  29. ncbi request reprint Escitalopram reduces attentional performance in anxious older adults with high-expression genetic variants at serotonin 2A and 1B receptors
    Eric J Lenze
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Int J Neuropsychopharmacol 16:279-88. 2013
    ..These results, if confirmed, could lead to the personalization of SSRI use to reduce adverse neurocognitive effects...
  30. ncbi request reprint Adverse effects of depression and cognitive impairment on rehabilitation participation and recovery from hip fracture
    Eric J Lenze
    Intervention Research Center for the Study of Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Int J Geriatr Psychiatry 19:472-8. 2004
    ..Our goal was to determine whether any association of depression and cognitive impairment with rehabilitation outcome is accounted for by more immediate effects of these variables on rehabilitation participation...
  31. pmc Salivary cortisol is associated with diagnosis and severity of late-life generalized anxiety disorder
    Rose C Mantella
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Psychoneuroendocrinology 33:773-81. 2008
    ..These data demonstrate HPA axis dysfunction in late-life GAD and suggest the need for additional research on the influence of aging on HPA axis function in mood and anxiety disorders...
  32. ncbi request reprint Significance of poor patient participation in physical and occupational therapy for functional outcome and length of stay
    Eric J Lenze
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Arch Phys Med Rehabil 85:1599-601. 2004
    ..To determine the frequency of poor patient participation during inpatient physical (PT) and occupational therapy (OT) sessions and to examine the influence of poor participation on functional outcome and length of stay (LOS)...
  33. ncbi request reprint Effect of rehabilitation site on functional recovery after hip fracture
    Michael C Munin
    Department of Physical Medicine and Rehabilitation, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Arch Phys Med Rehabil 86:367-72. 2005
    ..To evaluate whether FIM instrument motor outcomes differ between hip fracture survivors undergoing rehabilitation in inpatient rehabilitation facilities (IRFs) and skilled nursing facilities (SNFs)...
  34. pmc Memantine for late-life depression and apathy after a disabling medical event: a 12-week, double-blind placebo-controlled pilot study
    Eric J Lenze
    Department of Psychiatry, Washington University, St Louis, MO, USA
    Int J Geriatr Psychiatry 27:974-80. 2012
    ..Therefore, we examined whether memantine could reduce depressive symptoms and amotivation manifesting in older adults after a disabling medical event, thereby improving their functional recovery...
  35. ncbi request reprint Preventing depression in medical illness: a new lead?
    Charles F Reynolds
    Advanced Center for Interventions and Services Research for Late Life Mood Disorders, University of Pittsburgh School of Medicine, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 64:884-5. 2007
  36. pmc Cognitive and affective predictors of rehabilitation participation after stroke
    Elizabeth R Skidmore
    Department of Occupational Therapy, University of Pittsburgh, Pittsburgh, PA, USA
    Arch Phys Med Rehabil 91:203-7. 2010
    ..To examine associations between cognitive and affective impairments and rehabilitation participation during stroke rehabilitation...
  37. pmc Rescue pharmacotherapy with duloxetine for selective serotonin reuptake inhibitor nonresponders in late-life depression: outcome and tolerability
    Jordan F Karp
    Western Psychiatric Institute and Clinic, Advanced Center for Interventions and Services Research for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    J Clin Psychiatry 69:457-63. 2008
    ....
  38. pmc Generalized anxiety disorder severity scale validation in older adults
    Carmen Andreescu
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Geriatr Psychiatry 16:813-8. 2008
    ..Given the high prevalence of GAD in the elderly and the need for a validated scale to assess GAD severity in this age group, the authors examined the psychometric properties of the GADSS in the elderly...
  39. ncbi request reprint Clinically relevant behaviors in elderly hip fracture inpatients
    Helen H Dorra
    University of Pittsburgh School of Medicine, USA
    Int J Psychiatry Med 32:249-59. 2002
    ..To examine the range of behaviors documented by inpatient rehabilitation staff and the association of these behaviors with functional outcome, in elderly persons undergoing rehabilitation after hip fracture...
  40. pmc Escitalopram for older adults with generalized anxiety disorder: a randomized controlled trial
    Eric J Lenze
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, Box 8134, St Louis, MO 63110, USA
    JAMA 301:295-303. 2009
    ..Selective serotonin reuptake inhibitors (SSRIs) are efficacious for younger adults with GAD, but benefits and risks may be different in older adults...
  41. ncbi request reprint Achieving long-term optimal outcomes in geriatric depression and anxiety
    Benoit H Mulsant
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    CNS Spectr 8:27-34. 2003
    ....
  42. pmc Relation of serotonin transporter genetic variation to efficacy of escitalopram for generalized anxiety disorder in older adults
    Eric J Lenze
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, Box 8134, St Louis, MO 63110, USA
    J Clin Psychopharmacol 30:672-7. 2010
    ..We hypothesized that GAD patients with no La haplotypes (La⁻) have lower SSRI treatment efficacy than those with 1 to 2 La haplotypes (La+)...
  43. ncbi request reprint Time course of response to antidepressants in late-life major depression: therapeutic implications
    Ellen M Whyte
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Drugs Aging 21:531-54. 2004
    ..Better understanding of factors related to such differences may suggest new intervention strategies to accelerate response...
  44. ncbi request reprint Effect of cerebrovascular risk factors on depression treatment outcome in later life
    Mark D Miller
    Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Am J Geriatr Psychiatry 10:592-8. 2002
    ..This study tested the relationship of cerebrovascular risk factors (CVRF) to clinical presentation and treatment outcome in 156 subjects enrolled in a long-term maintenance treatment study of late-life recurrent major depression...
  45. ncbi request reprint Anxiety symptoms in elderly patients with depression: what is the best approach to treatment?
    Eric J Lenze
    Department of Psychiatry, Intervention Research Center in Late Life Mood Disorders, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Drugs Aging 19:753-60. 2002
    ..Therefore, optimism should be maintained when treating the depressed elderly individual, even when comorbid anxiety is present...
  46. doi request reprint Patient participation and physical activity during rehabilitation and future functional outcomes in patients after hip fracture
    Jaime B Talkowski
    Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA, USA
    Arch Phys Med Rehabil 90:618-22. 2009
    ..We hypothesized those participants who were more active during rehabilitation would have higher participation scores and better functional outcomes after hip fracture compared with those who were less active...
  47. ncbi request reprint Treatment considerations for anxiety in the elderly
    Eric J Lenze
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    CNS Spectr 8:6-13. 2003
    ..Overall, the research in late-life anxiety has not caught up to the literature in late-life depression and, for the most part, treatment recommendations must be extrapolated from studies in young adults...
  48. ncbi request reprint Influence of rehabilitation site on hip fracture recovery in community-dwelling subjects at 6-month follow-up
    Michael C Munin
    Department of Physical Medicine and Rehabilitation, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Arch Phys Med Rehabil 87:1004-6. 2006
    ..To evaluate whether postacute rehabilitation after hip fracture influences recovery of prefracture function as detected by the FIM instrument motor scale...
  49. ncbi request reprint The Pittsburgh Rehabilitation Participation Scale: reliability and validity of a clinician-rated measure of participation in acute rehabilitation
    Eric J Lenze
    Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Arch Phys Med Rehabil 85:380-4. 2004
    ..To demonstrate interrater reliability and predictive validity of the Pittsburgh Rehabilitation Participation Scale (PRPS), a clinician-rated 6-point Likert-type item measuring patient participation in inpatient rehabilitation sessions...
  50. pmc Dynamic prediction of treatment response in late-life depression
    Ian Joel
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA
    Am J Geriatr Psychiatry 22:167-76. 2014
    ..To identify actionable predictors of remission to antidepressant pharmacotherapy in depressed older adults and to use signal detection theory to develop decision trees to guide clinical decision making...
  51. pmc Enhanced medical rehabilitation increases therapy intensity and engagement and improves functional outcomes in postacute rehabilitation of older adults: a randomized-controlled trial
    Eric J Lenze
    Department of Psychiatry, Washington University, St Louis, MO, USA
    J Am Med Dir Assoc 13:708-12. 2012
    ..This study tested Enhanced Medical Rehabilitation, an intervention designed to increase patient engagement in, and intensity of, daily physical and occupational therapy sessions in postacute-care rehabilitation...
  52. ncbi request reprint Stroke-related knowledge and health behaviors among poststroke patients in inpatient rehabilitation
    Kris L Koenig
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Arch Phys Med Rehabil 88:1214-6. 2007
    ..To measure stroke knowledge and prestroke personal health behaviors of stroke patients undergoing inpatient rehabilitation and their caregivers...
  53. ncbi request reprint Predictors of adequacy of depression management in the primary care setting
    Jin H Joo
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213, USA
    Psychiatr Serv 56:1524-8. 2005
    ..This study examined the adequacy of antidepressant treatment and overall depression management by primary care physicians and identified patient characteristics related to inadequate care...
  54. pmc A lifespan view of anxiety disorders
    Eric J Lenze
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Dialogues Clin Neurosci 13:381-99. 2011
    ..Finally we describe optimal management of anxiety disorders across the lifespan, in "eight simple steps" for practitioners...
  55. pmc Do clinical rehabilitation education programs really improve stroke-related knowledge?
    Elizabeth R Skidmore
    Department of Occupational Therapy, School of Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Phys Med Rehabil 87:637-41. 2008
    ..We evaluated the effectiveness of a clinical stroke education program for improving stroke-related health knowledge after inpatient rehabilitation in a "real world" setting...
  56. pmc fMRI activation in late-life anxious depression: a potential biomarker
    Carmen Andreescu
    Department of Psychiatry, The Advanced Center in Interventions and Services Research for Late Life Mood Disorders, University of Pittsburgh School of Medicine and the John A Hartford Center of Excellence in Geriatric Psychiatry, Pittsburgh, PA, USA
    Int J Geriatr Psychiatry 24:820-8. 2009
    ..Subjects were trained on the Preparing to Overcome Prepotency (POP) task, which is an executive control task that reliably activates the lateral prefrontal cortex-anterior cingulate cortex (ACC) cognitive control circuit...
  57. ncbi request reprint Evidence-based treatment of geriatric anxiety disorders
    Julie Loebach Wetherell
    Department of Psychiatry, University of California San Diego, VA San Diego Healthcare System, 3350 La Jolla Village Drive 116B, San Diego, CA 92161, USA
    Psychiatr Clin North Am 28:871-96, ix. 2005
  58. pmc Physician office visits of adults for anxiety disorders in the United States, 1985-1998
    Jeffrey S Harman
    Intervention Research Centers for Mid and Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    J Gen Intern Med 17:165-72. 2002
    ..To determine the number of physician office visits by adults in which an anxiety disorder diagnosis was recorded and rates of treatment during these visits...
  59. doi request reprint Aripiprazole prescribing patterns and side effects in elderly psychiatric inpatients
    Kim C Coley
    University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15261, USA
    J Psychiatr Pract 15:150-3. 2009
    ..This analysis examined dosing patterns and safety of aripiprazole in elderly inpatients...
  60. ncbi request reprint Combined pharmacotherapy and psychotherapy as maintenance treatment for late-life depression: effects on social adjustment
    Eric J Lenze
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Psychiatry 159:466-8. 2002
    ..The authors hypothesized that elderly patients recovering from depression would have better social adjustment with medication and interpersonal psychotherapy than with medication or psychotherapy alone...
  61. ncbi request reprint Comorbidity of depression and anxiety in the elderly
    Eric J Lenze
    Intervention Research Center in Late Life Mood Disorders, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Room E1124, PA 15213, USA
    Curr Psychiatry Rep 5:62-7. 2003
    ..Future research areas are also addressed in this paper...
  62. pmc Research to reduce the suicide rate among older adults: methodology roadblocks and promising paradigms
    Katalin Szanto
    Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Psychiatr Serv 64:586-9. 2013
    ....
  63. pmc Comorbid anxiety and depression: bête noire or quick fix?
    Carmen Andreescu
    Br J Psychiatry 200:179-81. 2012
    ..The most recent evidence from genetics, neuropeptide systems and functional neuroimaging suggests a valid diagnostic construct...

Research Grants1