J A Lengyel

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint The odd-skipped family of zinc finger genes promotes Drosophila leg segmentation
    Irene Hao
    Waksman Institute, Rutgers, The State University of New Jersey, 190 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Dev Biol 263:282-95. 2003
  2. ncbi request reprint It takes guts: the Drosophila hindgut as a model system for organogenesis
    Judith A Lengyel
    Department of Molecular, Cell, and Developmental Biology, University of California at Los Angeles, Los Angeles, California 90095 1606, USA
    Dev Biol 243:1-19. 2002
  3. ncbi request reprint Posterior gut development in Drosophila: a model system for identifying genes controlling epithelial morphogenesis
    J A Lengyel
    Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles 90095 1606, USA
    Cell Res 8:273-84. 1998
  4. ncbi request reprint drumstick, bowl, and lines are required for patterning and cell rearrangement in the Drosophila embryonic hindgut
    D D Iwaki
    Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, California 90095 1606, USA
    Dev Biol 240:611-26. 2001
  5. ncbi request reprint The control of cell fate in the embryonic visual system by atonal, tailless and EGFR signaling
    A Daniel
    Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095 1606, USA
    Development 126:2945-54. 1999
  6. ncbi request reprint Role of caudal in hindgut specification and gastrulation suggests homology between Drosophila amnioproctodeal invagination and vertebrate blastopore
    L H Wu
    Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095 1606, USA
    Development 125:2433-42. 1998
  7. ncbi request reprint Complex regulatory region mediating tailless expression in early embryonic patterning and brain development
    K M Rudolph
    Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095 1606, USA
    Development 124:4297-308. 1997
  8. ncbi request reprint Drosophila brachyenteron regulates gene activity and morphogenesis in the gut
    J B Singer
    Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095 1606, USA
    Development 122:3707-18. 1996
  9. ncbi request reprint Drosophila arc encodes a novel adherens junction-associated PDZ domain protein required for wing and eye development
    X Liu
    Department of Molecular, Cell, and Developmental Biology, University of California at Los Angeles, Los Angeles, California, 90095 1606, USA
    Dev Biol 221:419-34. 2000
  10. pmc Conversion of dorsal from an activator to a repressor by the global corepressor Groucho
    T Dubnicoff
    Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, USA
    Genes Dev 11:2952-7. 1997

Collaborators

  • X Liu
  • G Chen
  • Z Paroush
  • I Kiss
  • Victor Hatini
  • Cordelia Rauskolb
  • Katherine A Johansen
  • Ryan B Green
  • D David Iwaki
  • J B Singer
  • A Daniel
  • Irene Hao
  • Parthive H Patel
  • V Hartenstein
  • Yueh Jung Chen
  • D D Iwaki
  • A J Courey
  • T Dubnicoff
  • K M Rudolph
  • G J Liaw
  • C Nassif
  • L H Wu
  • Nitika Thapar
  • Jeniffer B Hernandez
  • John Maris
  • Monica Martinez
  • Fuyuhiko Tamanoi
  • Chia Ling Gau
  • Olga Dunaevsky
  • Lea Guo
  • Gwo Jen Liaw
  • R Harbecke
  • R J Diaz
  • Chuen Sheue Chiang
  • Li Chuan Weng
  • K A Johansen
  • K Dumstrei
  • T Shi
  • P Green
  • S A Valentine
  • F Pignoni
  • T Kusch
  • R Reuter
  • W Janning
  • J D Huang

Detail Information

Publications22

  1. ncbi request reprint The odd-skipped family of zinc finger genes promotes Drosophila leg segmentation
    Irene Hao
    Waksman Institute, Rutgers, The State University of New Jersey, 190 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Dev Biol 263:282-95. 2003
    ....
  2. ncbi request reprint It takes guts: the Drosophila hindgut as a model system for organogenesis
    Judith A Lengyel
    Department of Molecular, Cell, and Developmental Biology, University of California at Los Angeles, Los Angeles, California 90095 1606, USA
    Dev Biol 243:1-19. 2002
    ....
  3. ncbi request reprint Posterior gut development in Drosophila: a model system for identifying genes controlling epithelial morphogenesis
    J A Lengyel
    Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles 90095 1606, USA
    Cell Res 8:273-84. 1998
    ..We describe approaches to identify additional genes that are required for morphogenesis of these simple epithelia, particularly those that might play a structural role by affecting cell adhesion and cell shape...
  4. ncbi request reprint drumstick, bowl, and lines are required for patterning and cell rearrangement in the Drosophila embryonic hindgut
    D D Iwaki
    Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, California 90095 1606, USA
    Dev Biol 240:611-26. 2001
    ..The close association of both cell rearrangement and patterning defects in all three mutants suggest that proper patterning of the hindgut into small intestine and large intestine is likely required for its correct morphogenesis...
  5. ncbi request reprint The control of cell fate in the embryonic visual system by atonal, tailless and EGFR signaling
    A Daniel
    Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095 1606, USA
    Development 126:2945-54. 1999
    ..The regulators of tll expression in the embryonic visual system remain elusive, as we were unable to find evidence for regulation by the 'early eye genes' so, eya and ey, or by EGFR signaling...
  6. ncbi request reprint Role of caudal in hindgut specification and gastrulation suggests homology between Drosophila amnioproctodeal invagination and vertebrate blastopore
    L H Wu
    Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095 1606, USA
    Development 125:2433-42. 1998
    ....
  7. ncbi request reprint Complex regulatory region mediating tailless expression in early embryonic patterning and brain development
    K M Rudolph
    Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095 1606, USA
    Development 124:4297-308. 1997
    ....
  8. ncbi request reprint Drosophila brachyenteron regulates gene activity and morphogenesis in the gut
    J B Singer
    Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095 1606, USA
    Development 122:3707-18. 1996
    ..Although byn is not expressed in the midgut or the Malpighian tubules, it is required for the formation of midgut constrictions and for the elongation of the Malpighian tubules...
  9. ncbi request reprint Drosophila arc encodes a novel adherens junction-associated PDZ domain protein required for wing and eye development
    X Liu
    Department of Molecular, Cell, and Developmental Biology, University of California at Los Angeles, Los Angeles, California, 90095 1606, USA
    Dev Biol 221:419-34. 2000
    ..Misexpression of arc in the eye imaginal discs results in rough and larger eyes with fused ommatidia. We propose that arc affects eye development by modulating adherens junctions of the developing ommatidium...
  10. pmc Conversion of dorsal from an activator to a repressor by the global corepressor Groucho
    T Dubnicoff
    Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, USA
    Genes Dev 11:2952-7. 1997
    ..Groucho is therefore a critical component of the dorsal/ventral patterning system...
  11. ncbi request reprint The role of morphogenetic cell death during Drosophila embryonic head development
    C Nassif
    Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles 90095 1606, USA
    Dev Biol 197:170-86. 1998
    ..g., retraction of the clypeolabrum, formation of the dorsal pouch, fusion of lateral gnathal lobes) are evolutionarily more recent and fail to occur normally in rpr-deficient embryos...
  12. pmc Identification of genes controlling malpighian tubule and other epithelial morphogenesis in Drosophila melanogaster
    X Liu
    Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, California 90095, USA
    Genetics 151:685-95. 1999
    ..Finally, from the same screen, we identified a second novel gene, drumstick, that affects only foregut and hindgut morphogenesis...
  13. ncbi request reprint Graded effect of tailless on posterior gut development: molecular basis of an allelic series of a nuclear receptor gene
    R J Diaz
    Department of Molecular, Cell and Developmental Biology, UCLA 90095 1606, USA
    Mech Dev 54:119-30. 1996
    ....
  14. ncbi request reprint Expression and sequence analysis of the Drosophila blastoderm-specific gene bsg25A
    J B Singer
    University of California, Los Angeles, Department of Molecular, Cell and Developmental Biology 90095 1606, USA
    Gene 197:379-82. 1997
    ..On the basis of its temporally restricted expression and its polytene chromosomal map position at 25A1,2, we have designated this gene blastoderm-specific gene 25A (bsg25A). bsg25A encodes a novel protein of 23 kDa...
  15. ncbi request reprint The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression
    G J Liaw
    Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles 90095, USA
    Genes Dev 9:3163-76. 1995
    ....
  16. ncbi request reprint Drumstick is a zinc finger protein that antagonizes Lines to control patterning and morphogenesis of the Drosophila hindgut
    Ryan B Green
    Molecular Biology Institute, UCLA, Los Angeles, CA 90095 1606, USA
    Development 129:3645-56. 2002
    ..We have thus defined a pathway in which a spatially localized zinc finger protein antagonizes a globally expressed protein, thereby leading to specification of a domain (the small intestine) necessary for oriented cell rearrangement...
  17. ncbi request reprint A Delta-Notch signaling border regulated by Engrailed/Invected repression specifies boundary cells in the Drosophila hindgut
    D David Iwaki
    Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095 1606, USA
    Mech Dev 114:71-84. 2002
    ..This Notch-induced cell specification is distinguished by the fact that it does not appear to utilize the ligand Serrate and the modulator Fringe...
  18. ncbi request reprint Localized JAK/STAT signaling is required for oriented cell rearrangement in a tubular epithelium
    Katherine A Johansen
    Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095 1606, USA
    Development 130:135-45. 2003
    ..These results provide the first example in which JAK/STAT signaling plays a required role in orienting cell rearrangement that elongates an epithelium...
  19. ncbi request reprint The Drm-Bowl-Lin relief-of-repression hierarchy controls fore- and hindgut patterning and morphogenesis
    Katherine A Johansen
    Department of Molecular, Cell, and Developmental Biology, University of California, Box 160606, Los Angeles, CA 90095 1606, USA
    Mech Dev 120:1139-51. 2003
    ..Since the odd-family and lin are conserved in mosquito, mouse, and humans, we propose that the odd-family genes and lin may also interact to control patterning and morphogenesis in other insects and in vertebrates...
  20. pmc The Drumstick/Lines/Bowl regulatory pathway links antagonistic Hedgehog and Wingless signaling inputs to epidermal cell differentiation
    Victor Hatini
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Genes Dev 19:709-18. 2005
    ..Thus, in all these developmental contexts, including the embryonic epidermis, the novel molecular regulatory pathway defined here is deployed in order to elaborate pattern across a field of cells...
  21. ncbi request reprint Tramtrack69 is required for the early repression of tailless expression
    Yueh Jung Chen
    Institute of Genetics, National Yang Ming University, Shih Pai, Taipei 112, Taiwan, ROC
    Mech Dev 116:75-83. 2002
    ..Further, in wild-type embryos, the tll-MRR mutated in TC5 drives uniform lacZ expression before late stage 4. We conclude that TTK69 is required for early (before the end of stage 4) repression of tll transcription...
  22. ncbi request reprint Drosophila Rheb GTPase is required for cell cycle progression and cell growth
    Parthive H Patel
    Molecular Biology Institute, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095 1489, USA
    J Cell Sci 116:3601-10. 2003
    ..In cultured cells, the effect of overexpressing dRheb was blocked by the addition of rapamycin. These results imply that dRheb is involved in TOR signaling...