E C Leira

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. doi request reprint Primary stroke centers should be located using maximal coverage models for optimal access
    Enrique C Leira
    Division of Cerebrovascular Diseases, Carver College of Medicine, Iowa City, IA, USA
    Stroke 43:2417-22. 2012
  2. doi request reprint Lack of international consensus on ethical aspects of acute stroke trials
    Enrique C Leira
    Department of Neurology, Carver College of Medicine, Iowa City, Iowa, USA
    J Stroke Cerebrovasc Dis 21:200-4. 2012
  3. doi request reprint The types of neurological deficits might not justify withholding treatment in patients with low total National Institutes of Health Stroke Scale scores
    Enrique C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    Stroke 43:782-6. 2012
  4. doi request reprint Education Research: The challenge of incorporating formal research methodology training in a neurology residency
    E C Leira
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    Neurology 70:e79-84. 2008
  5. doi request reprint Rural-urban differences in acute stroke management practices: a modifiable disparity
    Enrique C Leira
    Department of Neurology, 2147 RCP, University of Iowa College of Medicine, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Arch Neurol 65:887-91. 2008
  6. pmc Baseline NIH stroke scale responses estimate the probability of each particular stroke subtype
    E C Leira
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Cerebrovasc Dis 26:573-7. 2008
  7. ncbi request reprint Strategies to improve acute stroke care of patients in rural and other geographically dispersed areas
    R Charles Callison
    Enrique C Leira, MD, MS Department of Neurology, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Curr Treat Options Neurol 10:450-4. 2008
  8. ncbi request reprint Development of an emergency department response to acute stroke ("Code Stroke")
    Enrique C Leira
    Department of Neurology, University of Iowa, 2147 RCP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Curr Neurol Neurosci Rep 9:35-40. 2009
  9. pmc Extending acute trials to remote populations: a pilot study during interhospital helicopter transfer
    Enrique C Leira
    Department of Neurology, Carver College of Medicine, Iowa City, Iowa, USA
    Stroke 40:895-901. 2009
  10. ncbi request reprint Improving prediction of outcome in "good grade" subarachnoid hemorrhage
    Enrique C Leira
    Department of Neurology, Division of Cerebrovascular Diseases, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Neurosurgery 61:470-3; discussion 473-4. 2007

Detail Information

Publications23

  1. doi request reprint Primary stroke centers should be located using maximal coverage models for optimal access
    Enrique C Leira
    Division of Cerebrovascular Diseases, Carver College of Medicine, Iowa City, IA, USA
    Stroke 43:2417-22. 2012
    ..An alternative, directed, algorithmic approach to determine near optimal locations of PSCs would be justified if it significantly improves coverage...
  2. doi request reprint Lack of international consensus on ethical aspects of acute stroke trials
    Enrique C Leira
    Department of Neurology, Carver College of Medicine, Iowa City, Iowa, USA
    J Stroke Cerebrovasc Dis 21:200-4. 2012
    ..The absence of an ethical consensus can become a barrier to advancing stroke treatment internationally...
  3. doi request reprint The types of neurological deficits might not justify withholding treatment in patients with low total National Institutes of Health Stroke Scale scores
    Enrique C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    Stroke 43:782-6. 2012
    ....
  4. doi request reprint Education Research: The challenge of incorporating formal research methodology training in a neurology residency
    E C Leira
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    Neurology 70:e79-84. 2008
    ....
  5. doi request reprint Rural-urban differences in acute stroke management practices: a modifiable disparity
    Enrique C Leira
    Department of Neurology, 2147 RCP, University of Iowa College of Medicine, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Arch Neurol 65:887-91. 2008
    ....
  6. pmc Baseline NIH stroke scale responses estimate the probability of each particular stroke subtype
    E C Leira
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Cerebrovasc Dis 26:573-7. 2008
    ....
  7. ncbi request reprint Strategies to improve acute stroke care of patients in rural and other geographically dispersed areas
    R Charles Callison
    Enrique C Leira, MD, MS Department of Neurology, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Curr Treat Options Neurol 10:450-4. 2008
    ....
  8. ncbi request reprint Development of an emergency department response to acute stroke ("Code Stroke")
    Enrique C Leira
    Department of Neurology, University of Iowa, 2147 RCP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Curr Neurol Neurosci Rep 9:35-40. 2009
    ..On the other hand, maintaining proficiency of the team's operation is time consuming and personally onerous for team responders. Successful maintenance requires strong departmental and institutional commitment...
  9. pmc Extending acute trials to remote populations: a pilot study during interhospital helicopter transfer
    Enrique C Leira
    Department of Neurology, Carver College of Medicine, Iowa City, Iowa, USA
    Stroke 40:895-901. 2009
    ..The purposes of this study were to evaluate the safety and acceptability of initiating acute stroke trials during early helicopter evacuation and to test an intervention to facilitate informed consent...
  10. ncbi request reprint Improving prediction of outcome in "good grade" subarachnoid hemorrhage
    Enrique C Leira
    Department of Neurology, Division of Cerebrovascular Diseases, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Neurosurgery 61:470-3; discussion 473-4. 2007
    ..We hypothesize that subtle neurological signs at baseline could be present in some "good grade" subarachnoid hemorrhage (SAH) patients and that they would have negative prognostic implications...
  11. ncbi request reprint Slow progressive acceptance of intravenous thrombolysis for patients with stroke by rural primary care physicians
    Enrique C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Arch Neurol 64:518-21. 2007
    ..In the rural United States, patients with stroke are usually first evaluated locally by a nonneurologist physician (NNP) before treatment is determined...
  12. ncbi request reprint Feasibility of acute clinical trials during aerial interhospital transfer
    Enrique C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, 2 RCP, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA 52246, USA
    Stroke 37:2504-7. 2006
    ..If acute clinical research were feasible during the aerial interhospital transport, more patients might be enrolled in trials at a critical earlier stage...
  13. ncbi request reprint Blood pressure surge precedes intracerebral hemorrhage
    Enrique C Leira
    Department of Neurology 2 RCP, University of Iowa, Iowa City, IA 52246, USA
    Neurocrit Care 2:43-5. 2005
    ..Several case reports have attributed ICH to specific situations in which the BP was inferred to be high. Unfortunately, those cases lacked continuous monitoring of BP and neurological exam...
  14. ncbi request reprint A novel, simple pressure safety valve for lumbar puncture
    Enrique C Leira
    Department of Neurology, The Souers Stroke Institute, St Louis, MO, USA
    Neurocrit Care 3:68-70. 2005
  15. ncbi request reprint Improving pilot response to in-flight strokes: a randomized controlled trial
    Enrique C Leira
    Department of Neurology, School of Medicine, Saint Louis University, Missouri, USA
    Cerebrovasc Dis 19:317-22. 2005
    ..Pilot pro-activeness towards IFS could improve outcome and should be promoted. Unfortunately, little is known about a pilot's stroke pro-activeness or limiting factors...
  16. ncbi request reprint Management of acute ischemic stroke
    E C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, University of Iowa, Iowa City 52242, USA
    Clin Geriatr Med 15:701-20. 1999
    ..The key to modern treatment is the emergent administration of tissue plasminogen activator (rtPA). Thrombocyte treatment improves outcome when it is given within 3 hours of onset of stroke to carefully selected patients...
  17. doi request reprint Treating patients with 'wake-up' stroke: the experience of the AbESTT-II trial
    Harold P Adams
    Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    Stroke 39:3277-82. 2008
    ..We elected to test the safety and possible efficacy of abciximab in treatment of enrolled subjects with wake-up stroke...
  18. ncbi request reprint Can we predict early recurrence in acute stroke?
    Enrique C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Cerebrovasc Dis 18:139-44. 2004
    ..The ability to predict which patients are at risk for early recurrence would be useful for both the management and design of clinical trials...
  19. ncbi request reprint Baseline NIH Stroke Scale score strongly predicts outcome after stroke: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST)
    H P Adams
    Department of Neurology, University of Iowa College of Medicine, Iowa City 52242, USA
    Neurology 53:126-31. 1999
    ..To compare the baseline National Institutes of Health Stroke Scale (NIHSS) score and the Trial of Org 10172 in Acute Stroke Treatment (TOAST) stroke subtype as predictors of outcomes at 7 days and 3 months after ischemic stroke...
  20. ncbi request reprint [Treatment of acute stroke]
    E C Leira
    Department of Neurology, 5FDT St Louis University Hospital 3635 Vista Ave at Grand St Louis, MO 63110, USA
    Rev Neurol 36:86-92. 2003
    ..Intra arterial thrombolysis is a promising therapy for patients with occlusion of the middle cerebral artery, which has been contrasted angiographically and is less than 6 hours old...
  21. ncbi request reprint Early recovery after cerebral ischemia risk of subsequent neurological deterioration
    S Claiborne Johnston
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Ann Neurol 54:439-44. 2003
    ..7-5.2; p < 0.001). Among patients with acute cerebral ischemia, those who recover substantially within 24 hours may be at greater risk of subsequent neurological deterioration due to causes other than hemorrhage...
  22. doi request reprint Toward fully automated processing of dynamic susceptibility contrast perfusion MRI for acute ischemic cerebral stroke
    Jinsuh Kim
    Department of Radiology, University of Iowa, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Comput Methods Programs Biomed 98:204-13. 2010
    ..Our streamlined method also offers promise for further development of automated quantitative analysis of the ischemic penumbra...
  23. ncbi request reprint Continuous or emergent EEG: can bedside caregivers recognize epileptiform discharges?
    Enrique C Leira
    Souers Stroke Institute, Department of Neurology, Saint Louis University, 3635 Vista Ave at Grand Blvd, St Louis, MO 63110, USA
    Intensive Care Med 30:207-12. 2004
    ..We assessed the ability to recognize epileptiform discharges among various nonexpert bedside caregivers. A second objective was to determine whether such skill improves with a simple educational intervention...