Detail Information
Publications
Characterization of NR13-related human cell death regulator, Boo/Diva, in normal and cancer tissuesR Lee
Huntsman Cancer Institute and Section of Oncology, Department of Medicine, University of Utah, Salt Lake City, UT 84112, USA
Biochim Biophys Acta 1520:187-94. 2001..Moreover, we found that genomic DNAs of three of 24 human cervical cancer samples display deletions within their Boo/Diva genes. This result suggests a role for human Boo/Diva in the pathogenesis of cervical cancer...
Regulation of cell survival by secreted proneurotrophinsR Lee
Division of Hematology, Department of Medicine, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
Science 294:1945-8. 2001..The biological action of neurotrophins is thus regulated by proteolytic cleavage, with proforms preferentially activating p75NTR to mediate apoptosis and mature forms activating Trk receptors to promote survival...
