Randall J Lee

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint The relative importance of left atrial function versus dimension in predicting atrial fibrillation after coronary artery bypass graft surgery
    Toshiko Nakai
    Department of Medicine, Section of Cardiac Electrophysiology, and Cardiovascular Research Institute, University of California, San Francisco 94143, USA
    Am Heart J 143:181-6. 2002
  2. ncbi request reprint Antibody targeting of stem cells to infarcted myocardium
    Randall J Lee
    Department of Medicine and Cardiovascular Research Institute, University of California San Francisco, 500 Parnassus Avenue, San Francisco, CA 94143 1354, USA
    Stem Cells 25:712-7. 2007
  3. doi request reprint Polymer-based restoration of left ventricular mechanics
    Randall J Lee
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, USA
    Cell Transplant 22:529-33. 2013
  4. pmc Targeted in vivo extracellular matrix formation promotes neovascularization in a rodent model of myocardial infarction
    Shirley S Mihardja
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 5:e10384. 2010
  5. pmc Pleiotrophin gene therapy for peripheral ischemia: evaluation of full-length and truncated gene variants
    Qizhi Fang
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e61413. 2013
  6. ncbi request reprint Catheter-based left atrial appendage (LAA) ligation for the prevention of embolic events arising from the LAA: initial experience in a canine model
    Randall J Lee
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA
    Circ Cardiovasc Interv 3:224-9. 2010
  7. doi request reprint Stem cells for myocardial repair and regeneration: where are we today?
    Randall J Lee
    Department of Medicine, Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, USA
    Methods Mol Biol 660:1-6. 2010
  8. doi request reprint Restoration of left ventricular geometry and improvement of left ventricular function in a rodent model of chronic ischemic cardiomyopathy
    Jiashing Yu
    University of California Berkeley and University of California San Francisco Joint Bioengineering Graduate Group, Berkeley San Francisco, CA, USA
    J Thorac Cardiovasc Surg 137:180-7. 2009
  9. doi request reprint The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat
    Jiashing Yu
    University of California Berkeley and University of California San Francisco Joint Bioengineering Graduate Group, Berkeley San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
    Biomaterials 31:7012-20. 2010
  10. pmc Intracardiac and extracardiac markers of inflammation during atrial fibrillation
    Gregory M Marcus
    Division of Cardiology, University of California, San Francisco, CA, USA
    Heart Rhythm 7:149-54. 2010

Collaborators

Detail Information

Publications65

  1. ncbi request reprint The relative importance of left atrial function versus dimension in predicting atrial fibrillation after coronary artery bypass graft surgery
    Toshiko Nakai
    Department of Medicine, Section of Cardiac Electrophysiology, and Cardiovascular Research Institute, University of California, San Francisco 94143, USA
    Am Heart J 143:181-6. 2002
    ..The purpose of this study was to determine whether pre-existing left atrial dysfunction is a predictor of postoperative AF compared with other clinical predictors...
  2. ncbi request reprint Antibody targeting of stem cells to infarcted myocardium
    Randall J Lee
    Department of Medicine and Cardiovascular Research Institute, University of California San Francisco, 500 Parnassus Avenue, San Francisco, CA 94143 1354, USA
    Stem Cells 25:712-7. 2007
    ..01). Bispecific antibody targeting offers a unique means to improve the delivery of stem cells to facilitate organ repair and a tool to study stem cell biology...
  3. doi request reprint Polymer-based restoration of left ventricular mechanics
    Randall J Lee
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, USA
    Cell Transplant 22:529-33. 2013
    ..A review of the rationale for an in situ tissue engineering approach for this treatment of heart failure and early clinical results of the Algisyl-LVR™ program are presented...
  4. pmc Targeted in vivo extracellular matrix formation promotes neovascularization in a rodent model of myocardial infarction
    Shirley S Mihardja
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 5:e10384. 2010
    ..We investigated whether extracellular matrix protein fragments could be targeted with antibodies to ischemically injured myocardium to promote angiogenesis and myocardial repair...
  5. pmc Pleiotrophin gene therapy for peripheral ischemia: evaluation of full-length and truncated gene variants
    Qizhi Fang
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e61413. 2013
    ....
  6. ncbi request reprint Catheter-based left atrial appendage (LAA) ligation for the prevention of embolic events arising from the LAA: initial experience in a canine model
    Randall J Lee
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA
    Circ Cardiovasc Interv 3:224-9. 2010
    ..A novel catheter-based approach for LAA ligation was evaluated for safety and effectiveness in a canine model...
  7. doi request reprint Stem cells for myocardial repair and regeneration: where are we today?
    Randall J Lee
    Department of Medicine, Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, USA
    Methods Mol Biol 660:1-6. 2010
    ..The overview provides the rationale for use of stem cells in myocardial repair. Potential stem cell types and technological challenges are highlighted...
  8. doi request reprint Restoration of left ventricular geometry and improvement of left ventricular function in a rodent model of chronic ischemic cardiomyopathy
    Jiashing Yu
    University of California Berkeley and University of California San Francisco Joint Bioengineering Graduate Group, Berkeley San Francisco, CA, USA
    J Thorac Cardiovasc Surg 137:180-7. 2009
    ..Various approaches to myocardial reconstruction have been developed for the treatment of congestive heart failure resulting from ischemic cardiomyopathy...
  9. doi request reprint The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat
    Jiashing Yu
    University of California Berkeley and University of California San Francisco Joint Bioengineering Graduate Group, Berkeley San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
    Biomaterials 31:7012-20. 2010
    ....
  10. pmc Intracardiac and extracardiac markers of inflammation during atrial fibrillation
    Gregory M Marcus
    Division of Cardiology, University of California, San Francisco, CA, USA
    Heart Rhythm 7:149-54. 2010
    ....
  11. pmc The effect of polypyrrole on arteriogenesis in an acute rat infarct model
    Shirley S Mihardja
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA
    Biomaterials 29:4205-10. 2008
    ..The results of this study highlight the potential clinical benefit of using this alginate-polypyrrole polymer blend as an injectable scaffold to repair ischemic myocardium after myocardial infarction...
  12. ncbi request reprint Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function
    Bo Qing Zhu
    Department of Medicine, Cardiology Research, VA Medical Center, University of California, San Francisco, 94143 0124, USA
    J Renin Angiotensin Aldosterone Syst 4:31-7. 2003
    ..The present study was undertaken to see if aspirin (ASA) antagonised the beneficial effects of captopril or losartan...
  13. ncbi request reprint Alcohol intake is significantly associated with atrial flutter in patients under 60 years of age and a shorter right atrial effective refractory period
    Gregory M Marcus
    Division of Cardiology, Electrophysiology Section, University of California, San Francisco, San Francisco, California, USA
    Pacing Clin Electrophysiol 31:266-72. 2008
    ..Although evidence suggests that alcohol is associated with atrial fibrillation (AF), the association between alcohol and atrial flutter (AFL) has not been examined. The mechanism connecting alcohol and atrial arrhythmias is unknown...
  14. pmc Protracted CRP elevation after atrial fibrillation ablation
    James M McCabe
    Division of Cardiology, Electrophysiology Section, University of California, San Francisco, California, USA
    Pacing Clin Electrophysiol 31:1146-51. 2008
    ..We hypothesized that this early recurrence is due to an inflammatory response to the ablation itself. We therefore sought to evaluate levels of CRP after AF ablation...
  15. pmc Extracellular matrix-derived peptides and myocardial repair
    Shirley S Mihardja
    Cardiovascular Research Institute, University of California San Francisco, CA, USA
    Cell Adh Migr 5:111-3. 2011
    ..Our results indicate a potentially new strategy for repairing damaged tissue...
  16. pmc Regional left atrial voltage in patients with atrial fibrillation
    Gregory M Marcus
    Division of Cardiology, Electrophysiology Section, University of California, San Francisco, San Francisco, California 94143 1354, USA
    Heart Rhythm 4:138-44. 2007
    ..Regional differences in fibrosis, particularly related to the posterior wall and septum, may be important in atrial fibrillation (AF). Using electroanatomic mapping, voltage can be used as a measure of fibrosis...
  17. pmc Randomized trial of conventional transseptal needle versus radiofrequency energy needle puncture for left atrial access (the TRAVERSE-LA study)
    Jonathan C Hsu
    Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA
    J Am Heart Assoc 2:e000428. 2013
    ..We sought to investigate the comparative effectiveness of an RF versus conventional needle for transseptal LA access...
  18. pmc Alcohol and vagal tone as triggers for paroxysmal atrial fibrillation
    Mala C Mandyam
    Division of Cardiology, Electrophysiology Section, University of California, San Francisco, San Francisco, CA, USA
    Am J Cardiol 110:364-8. 2012
    ..Alcohol and vagal triggers often were found in the same patients with PAF, raising the possibility that alcohol may precipitate AF by vagal mechanisms...
  19. doi request reprint Prospective observations in the clinical and electrophysiological characteristics of intra-isthmus reentry
    Yanfei Yang
    University of California San Francisco, San Francisco, California 94143 1354, USA
    J Cardiovasc Electrophysiol 21:1099-106. 2010
    ..Intra-isthmus reentry (IIR) is a circuit within the cavotricuspid isthmus (CTI). The purpose of this study is to prospectively define the electrogram and surface ECG characteristics of IIR, and its clinical implications...
  20. pmc A first-degree family history in lone atrial fibrillation patients
    Gregory M Marcus
    Division of Cardiology, Electrophysiology Section, University of California, San Francisco, California, USA
    Heart Rhythm 5:826-30. 2008
    ..A family history of AF in lone AF patients has not previously been compared with a family history of patients with AF and established risk factors (non-lone AF)...
  21. ncbi request reprint Impact of remote magnetic catheter navigation on ablation fluoroscopy and procedure time
    Albert M Kim
    University of California, San Francisco, California, USA
    Pacing Clin Electrophysiol 31:1399-404. 2008
    ..Remote magnetic catheter navigation (RCN) is gaining acceptance in clinical cardiac electrophysiology, but details regarding how RCN affects procedure execution are not well characterized...
  22. ncbi request reprint Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium
    Karen L Christman
    University of California Berkeley and San Francisco Joint Bioengineering Graduate Group, San Francisco, California, USA
    J Am Coll Cardiol 44:654-60. 2004
    ..In this study, we determined whether fibrin glue improves cell transplant retention and survival, reduces infarct expansion, and induces neovasculature formation...
  23. ncbi request reprint Safety of new oral anticoagulants for patients undergoing atrial fibrillation ablation
    Gevorg Stepanyan
    Division of Cardiology, Department of Medicine, University of California, San Francisco, 500 Parnassus Avenue, MU, San Francisco, CA, 94143, USA
    J Interv Card Electrophysiol 40:33-8. 2014
    ..However, there is limited data regarding use around catheter ablation (CA) procedures...
  24. pmc Bone marrow-derived mesenchymal stem cells in fibrin augment angiogenesis in the chronically infarcted myocardium
    Ngan F Huang
    University of California San Francisco, Cardiac Electrophysiology, MU East Tower, Box 1354, 500 Parnassus Avenue, San Francisco, CA 94143 1354, USA
    Regen Med 4:527-38. 2009
    ....
  25. doi request reprint The effect of a peptide-modified thermo-reversible methylcellulose on wound healing and LV function in a chronic myocardial infarction rodent model
    Shirley S Mihardja
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA
    Biomaterials 34:8869-77. 2013
    ....
  26. ncbi request reprint Enhanced neovasculature formation in ischemic myocardium following delivery of pleiotrophin plasmid in a biopolymer
    Karen L Christman
    University of California Berkeley and San Francisco Joint Bioengineering Graduate Group, San Francisco, CA 94143, USA
    Biomaterials 26:1139-44. 2005
    ..In this study, we demonstrate that delivery of PTN plasmid in fibrin glue increases neovasculature formation compared to injection of the naked plasmid in saline...
  27. pmc Differences in accessory pathway location by sex and race
    Jonathan C Hsu
    University of California, San Francisco, CA, USA
    Heart Rhythm 7:52-6. 2010
    ..The etiology of accessory pathway (AP) formation is generally unknown...
  28. ncbi request reprint Increases in P-wave dispersion predict postoperative atrial fibrillation after coronary artery bypass graft surgery
    Joby Chandy
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, USA
    Anesth Analg 98:303-10, table of contents. 2004
    ..03, 95% CI: 1.01-1.05, P = 0.01) to be independent predictors of postoperative AF. No surgical factor was identified to be responsible for this postoperative change in atrial electrophysiology...
  29. ncbi request reprint Using extracellular matrix-derived peptides to alter the microenvironment for myocardial repair
    Shirley S Mihardja
    University of California San Francisco, Francisco, CA 94143, USA
    Curr Vasc Pharmacol 10:342-6. 2012
    ..This therapy opens up a potentially new non-invasive strategy for repairing damaged cardiac tissue...
  30. pmc Predictors of unusual ECG characteristics in cavotricuspid isthmus-dependent atrial flutter ablation
    Kurt S Hoffmayer
    San Francisco, California San Diego, CA 94143 1354, USA
    Pacing Clin Electrophysiol 34:1251-7. 2011
    ..An unusual 12-lead electrocardiographic pattern may be present in patients with cavotricuspid isthmus (CTI)-dependent flutter...
  31. ncbi request reprint MR guidance of targeted injections into border and core of scarred myocardium in pigs
    Maythem Saeed
    Department of Radiology, University of California San Francisco, 513 Parnassus Ave, Room HSW 207 B, San Francisco, CA 94143 0628, USA
    Radiology 240:419-26. 2006
    ....
  32. doi request reprint High-resolution optical mapping of ventricular tachycardia in rats with chronic myocardial infarction
    Chunhua Ding
    Cardiac Electrophysiology and Cardiovascular Research Institute, University of California, San Francisco, California 94143, USA
    Pacing Clin Electrophysiol 33:687-95. 2010
    ..We report a reproducible VT model in rats with chronic MI induced by ischemia-reperfusion and describe its electrophysiological characteristics using high-resolution optical mapping...
  33. pmc Pleiotrophin induces nitric oxide dependent migration of endothelial progenitor cells
    Christian Heiss
    Department of Medicine, Division of Cardiology, University of California, San Francisco, San Francisco, California 94143 0124, USA
    J Cell Physiol 215:366-73. 2008
    ..These data suggest that PTN may mediate its pro-angiogenic effects by increasing the local number of not only endothelial cells but also early EPCs at angiogenic sites...
  34. doi request reprint Electrophysiologic properties of para-Hisian atrial tachycardia
    Sei Iwai
    Department of Medicine, Division of Cardiology, Cornell University Medical Center, New York, New York, USA
    Heart Rhythm 8:1245-53. 2011
    ..Para-Hisian AT arising from the apex of the triangle of Koch has been considered to be a distinct entity, characterized by unique electrophysiological properties...
  35. pmc The effects of aging on apoptosis following myocardial infarction
    Andrew J Boyle
    Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA, USA Edyth and Eli Broad Center for Regenerative Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA
    Cardiovasc Ther 31:e102-10. 2013
    ..Aging is associated with higher incidence of heart failure and death following myocardial infarction (MI). The molecular and cellular changes that lead to these worse outcomes are not known...
  36. ncbi request reprint Biomaterials for the treatment of myocardial infarction
    Karen L Christman
    University of California Berkeley, Berkeley, California, USA
    J Am Coll Cardiol 48:907-13. 2006
    ..This review gives an overview of the current progress in the growing field of biomaterials for the treatment of MI...
  37. ncbi request reprint Pinhole single-photon emission computed tomography for myocardial perfusion imaging of mice
    Max C Wu
    Department of Radiology, University of California, San Francisco, California, USA
    J Am Coll Cardiol 42:576-82. 2003
    ....
  38. ncbi request reprint Chemical and physical regulation of stem cells and progenitor cells: potential for cardiovascular tissue engineering
    Ngan F Huang
    Joint Graduate Group in Bioengineering, University of California San Francisco and University of California Berkeley, Berkeley, California, USA
    Tissue Eng 13:1809-23. 2007
    ....
  39. ncbi request reprint Repeat transseptal catheterization after ablation for atrial fibrillation
    Gregory M Marcus
    Division of Cardiology, Electrophysiology Section, University of California, San Francisco, California 94143 1354, USA
    J Cardiovasc Electrophysiol 18:55-9. 2007
    ..The aim of this study was to determine the difficulty and/or success rates of repeat transseptal catheterization after left atrial ablation for AF...
  40. doi request reprint Predictors of axillary vein location for vascular access during pacemaker and defibrillator lead implantation
    Jonathan C Hsu
    Division of Cardiology, Electrophysiology Section, University of California, San Francisco, California, USA
    Pacing Clin Electrophysiol 34:1585-92. 2011
    ..We sought to describe variation in axillary vein location and identify predictors of a more cranial or caudal radiographic location to facilitate blind venous cannulation...
  41. pmc Markers of inflammation before and after curative ablation of atrial flutter
    Gregory M Marcus
    Division of Cardiology, Electrophysiology Section, University of California, San Francisco, San Francisco, California 94143 1354, USA
    Heart Rhythm 5:215-21. 2008
    ..Atrial arrhythmias are associated with inflammation. The cause and effect of the association are unknown...
  42. pmc Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches
    Junya Takagawa
    Department of Medicine, Division of Cardiology, University of California, San Francisco, 513 Parnassus Ave, Rm S1136, Box 0124, San Francisco, CA 94143 0124, USA
    J Appl Physiol 102:2104-11. 2007
    ....
  43. ncbi request reprint Percutaneous left atrial appendage occlusion (PLAATO) for preventing cardioembolism: first experience in canine model
    Toshiko Nakai
    Section of Cardiac Electrophysiology, Department of Medicine and Cardiovascular Research Institute, University of California, San Francisco 94143, USA
    Circulation 105:2217-22. 2002
    ..A novel implanted device for percutaneous LAA transcatheter occlusion (PLAATO) has been designed to seal the LAA. The purpose of this study was to test the feasibility and safety of transcatheter LAA occlusion in dogs...
  44. ncbi request reprint Atrial tachycardia arising from the coronary sinus musculature: electrophysiological characteristics and long-term outcomes of radiofrequency ablation
    Nitish Badhwar
    University of California, San Francisco, San Francisco, California 94143, USA
    J Am Coll Cardiol 46:1921-30. 2005
    ..We sought to describe the electrophysiological features and long-term outcome after radiofrequency catheter ablation (RFCA) of atrial tachycardia (AT) arising from the coronary sinus (CS) musculature...
  45. doi request reprint Remote navigation guided ablation of incessant atrial tachycardia in a patient with restricted venous access
    Albert M Kim
    UCSF Cardiac Electrophysiology, San Francisco, California 94143, USA
    J Cardiovasc Electrophysiol 20:1061-4. 2009
    ..This case demonstrates that remote navigation can facilitate the therapy of complex arrhythmias in challenging clinical situations...
  46. pmc Comparison of gene-transfer efficiency in human embryonic stem cells
    Feng Cao
    Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Edwards Building R354, Stanford, CA 94305 5344, USA
    Mol Imaging Biol 12:15-24. 2010
    ..The double-fusion construct provides an attractive approach for generating stable hES cell lines and monitoring engraftment and proliferation in vitro and in vivo...
  47. ncbi request reprint Virtual reality of stem cell transplantation to repair injured myocardium
    Lawrence G Lum
    Immunotherapy and Blood and Marrow Stem Cell Transplantation Programs, Adele R Decof Cancer Center, Department of Medicine, Brown University School of Medicine, USA
    J Cell Biochem 95:869-74. 2005
    ....
  48. ncbi request reprint Injectable biopolymers enhance angiogenesis after myocardial infarction
    Ngan F Huang
    UCSF UCB Joint Bioengineering Graduate Group, University of California Berkeley, Berkeley, California, USA
    Tissue Eng 11:1860-6. 2005
    ..The results of this study highlight the potential clinical benefit of these biopolymers as injectable scaffolds or cell delivery vehicles to the infarct zone after infarction...
  49. ncbi request reprint Protected circumferential conduction in the posterior atrioventricular vestibule of the left atrium: electrophysiologic and anatomic correlates
    Jie Cheng
    Cardiac Electrophysiology, University of California, San Francisco, CA 94143 1354, USA
    Pacing Clin Electrophysiol 28:692-701. 2005
    ..The anatomic substrate for protected isthmus conduction in the right atrium has been well defined. Little is known of similar substrates in the left atrium (LA)...
  50. ncbi request reprint Scarred myocardium imposes additional burden on remote viable myocardium despite a reduction in the extent of area with late contrast MR enhancement
    Maythem Saeed
    Department of Radiology, University of California, San Francisco, 94143 0628, USA
    Eur Radiol 16:827-36. 2006
    ..The integration of late enhancement and cine MRI incorporates anatomical and functional evaluation of remodeled hearts...
  51. pmc The aging heart and post-infarction left ventricular remodeling
    Henry Shih
    Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, California 94143, USA
    J Am Coll Cardiol 57:9-17. 2011
    ..We review the cellular and molecular aspects of post-infarction remodeling in the aged heart, and relate them to the clinical problem of post-infarction remodeling in elderly patients...
  52. pmc An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors
    Carissa Ritner
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e16004. 2011
    ..The identification of hMPs using this αMHC-GFP reporter line will provide important insight into the pathways regulating human myocardial development, and may provide a novel therapeutic reagent for the treatment of cardiac disease...
  53. ncbi request reprint Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction
    Karen L Christman
    University of California Berkeley and San Francisco Joint Bioengineering Graduate Group, San Francisco, California, USA
    Tissue Eng 10:403-9. 2004
    ..40, 0.44, 0.43, respectively). Fibrin glue is capable of preserving infarct wall thickness and cardiac function after a myocardial infarction in rats and may be useful as a biomaterial scaffold for myocardial cell transplantation...
  54. ncbi request reprint Usefulness of a ventricular extrastimulus from the summit of the ventricular septum in diagnosis of septal accessory pathway in patients with supraventricular tachycardia
    Takehiko Matsushita
    Section of Cardiac Electrophysiology, University of California San Francisco, San Francisco, California 94143, USA
    Am J Cardiol 93:643-6. 2004
    ..05). A VES during His bundle refractoriness from the RV summit increases the diagnostic yield for both the presence of an AP and its participation in the tachycardia circuit with respect to RV apical VES...
  55. ncbi request reprint The renin-angiotensin system does not contribute to the endothelial dysfunction and increased infarct size in rats exposed to second hand smoke
    Bo Qing Zhu
    Department of Medicine, University of California, San Francisco 94143 0124, USA
    J Renin Angiotensin Aldosterone Syst 3:54-60. 2002
    ..However, the potential interaction between SHS and the RAS is unknown...
  56. pmc Algisyl-LVR™ with coronary artery bypass grafting reduces left ventricular wall stress and improves function in the failing human heart
    Lik Chuan Lee
    Department of Surgery, University of California, San Francisco, CA, USA Department of Bioengineering, University of California, San Francisco, CA, USA
    Int J Cardiol 168:2022-8. 2013
    ..We sought to quantify the effects of a novel implantable hydrogel (Algisyl-LVR™) treatment in combination with coronary artery bypass grafting (i.e. Algisyl-LVR™+CABG) on both LV function and wall stress in heart failure patients...
  57. ncbi request reprint Surface electrocardiographic characteristics of right and left atrial flutter
    Andres Bochoeyer
    Cardiovascular Research Institute and Section of Cardiac Electrophysiology, University of California, San Francisco 94143 1354, USA
    Circulation 108:60-6. 2003
    ..There is little information about the surface expression of non-cavotricuspid isthmus (CTI)-dependent right atrial (RA) or left atrial (LA) flutter circuits...
  58. ncbi request reprint Postresuscitation stunning: postfibrillatory myocardial dysfunction caused by reduced myofilament Ca2+ responsiveness after ventricular fibrillation-induced myocyte Ca2+ overload
    Christian E Zaugg
    Department of Research, University Hospital Basel, Switzerland
    J Cardiovasc Electrophysiol 13:1017-24. 2002
    ..We tested whether this dysfunction can be caused by reduced myofilament Ca2+ responsiveness after VF-induced myocyte Ca2+ overload. We also tested whether electrical defibrillation shocks contribute to this dysfunction...
  59. ncbi request reprint Targeting of Lin-Sca+ hematopoietic stem cells with bispecific antibodies to injured myocardium
    Lawrence G Lum
    Immunotherapy Program, Adele R Decof Cancer Center, Providence, RI 02908, USA
    Blood Cells Mol Dis 32:82-7. 2004
    ..These results suggest that stem cells retargeted with BiAb can be directly injected and retained by injured myocardium or targeted to injured myocardial tissues for tissue regeneration...
  60. ncbi request reprint The new face of bispecific antibodies: targeting cancer and much more
    Lawrence G Lum
    Immunotherapy Program, Adele R Decof Cancer Center, Roger Williams Medical Center, Providence, RI 02908, USA
    Exp Hematol 34:1-6. 2006
    ....
  61. ncbi request reprint Histologic assessment of right atrial appendage myocardium in patients with atrial fibrillation after coronary artery bypass graft surgery
    Toshiko Nakai
    Division of Cardiovascular Medicine, Nihon University School of Medicine, Tokyo, Japan
    Cardiology 108:90-6. 2007
    ..85). These results suggest that the age-related atrial fibrosis rather than cellular hypertrophy may be important in the pathogenesis of AF after CABG surgery and should be further investigated...
  62. pmc Targeting human CD34+ hematopoietic stem cells with anti-CD45 x anti-myosin light-chain bispecific antibody preserves cardiac function in myocardial infarction
    Ting C Zhao
    Dept of Pediatrics, Women and Infants Hospital, Providence, RI 02905, USA
    J Appl Physiol (1985) 104:1793-800. 2008
    ..These results suggest that peripheral administration of armed CD34(+) HSC results in localization of CD34(+) HSC to injured myocardium and restores myocardial function...
  63. ncbi request reprint Pleiotrophin induces formation of functional neovasculature in vivo
    Karen L Christman
    University of California Berkeley and San Francisco Joint Bioengineering Graduate Group, USA
    Biochem Biophys Res Commun 332:1146-52. 2005
    ..The data suggest that PTN signals the more "complete" new blood vessel formation through its ability to stimulate different functions in different cell types not limited to the endothelial cell...
  64. ncbi request reprint A rodent model of myocardial infarction for testing the efficacy of cells and polymers for myocardial reconstruction
    Ngan F Huang
    University of California San Francisco and University of California Berkeley Joint Bioengineering Graduate Group, Berkeley, California, 94720 1762 USA
    Nat Protoc 1:1596-609. 2006
    ..The model can be created in 7 days or less, depending on the timing of therapeutic intervention...
  65. ncbi request reprint Tissue engineering and stem cell therapy for myocardial repair
    Yiping Gu
    University of California Berkeley and San Francisco Joint Bioengineering Graduate Group, USA
    Front Biosci 12:5157-65. 2007
    ..Here, we review the current progress in cardiac tissue repair and engineering; and discuss the new emerging technologies...

Research Grants2

  1. The influence of ischemic microenvironment and stem cell differentiation
    Randall Lee; Fiscal Year: 2007
    ..Specific aim 2: To test the hypothesis that the microenvironment influences SC differentiation, angiogenesis and LV remodeling. ..