P C Lee

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Impaired wound healing and angiogenesis in eNOS-deficient mice
    P C Lee
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Physiol 277:H1600-8. 1999
  2. ncbi request reprint Role of inducible nitric oxide synthase in transplant arteriosclerosis
    P C Lee
    Department of Surgery, University of Pittsburgh, PA 15261, USA
    Clin Exp Pharmacol Physiol 26:1013-5. 1999
  3. ncbi request reprint Nitric oxide induces angiogenesis and upregulates alpha(v)beta(3) integrin expression on endothelial cells
    P C Lee
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Microvasc Res 60:269-80. 2000
  4. ncbi request reprint Attenuation of myocardial ischemia/reperfusion injury by superinduction of inducible nitric oxide synthase
    S Kanno
    Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Circulation 101:2742-8. 2000
  5. ncbi request reprint A novel approach with magnetic resonance imaging used for the detection of lung allograft rejection
    S Kanno
    Department of Biological Sciences and Pittsburgh NMR Center for Biomedical Research, Carnegie Mellon University, and the Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    J Thorac Cardiovasc Surg 120:923-34. 2000
  6. ncbi request reprint Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats
    S Kanno
    Department of Biological Sciences and Pittsburgh NMR Center for Biomedical Research, Carnegie Mellon University, Pittsburgh, PA 15213 2683, USA
    Circulation 104:945-50. 2001
  7. ncbi request reprint Association of intraluminal thrombus in abdominal aortic aneurysm with local hypoxia and wall weakening
    D A Vorp
    Department of Surgery, University of Pittsburgh, PA, USA
    J Vasc Surg 34:291-9. 2001

Detail Information

Publications7

  1. ncbi request reprint Impaired wound healing and angiogenesis in eNOS-deficient mice
    P C Lee
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Physiol 277:H1600-8. 1999
    ..67 +/- 0.33 vessels/plug) compared with WT mice (10.17 +/- 0.79 vessels/plug). These results clearly show that eNOS plays a significant role in facilitating wound repair and growth factor-stimulated angiogenesis...
  2. ncbi request reprint Role of inducible nitric oxide synthase in transplant arteriosclerosis
    P C Lee
    Department of Surgery, University of Pittsburgh, PA 15261, USA
    Clin Exp Pharmacol Physiol 26:1013-5. 1999
    ..We have demonstrated that this exciting strategy is feasible and therapeutic and may improve the long-term survival and function of allografts. Future challenges include optimizing the methods and the vectors of gene delivery...
  3. ncbi request reprint Nitric oxide induces angiogenesis and upregulates alpha(v)beta(3) integrin expression on endothelial cells
    P C Lee
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Microvasc Res 60:269-80. 2000
    ..One possible mechanism might involve the upregulation of alpha(v)beta(3) integrin on endothelial cells, a critical mediator of cell-matrix adhesion and migration...
  4. ncbi request reprint Attenuation of myocardial ischemia/reperfusion injury by superinduction of inducible nitric oxide synthase
    S Kanno
    Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Circulation 101:2742-8. 2000
    ..Nitric oxide (NO) has been implicated as a mediator in myocardial ischemia/reperfusion (I/R) injury, but its functional properties have been conflicting. We investigated whether NO has a protective role against I/R injury...
  5. ncbi request reprint A novel approach with magnetic resonance imaging used for the detection of lung allograft rejection
    S Kanno
    Department of Biological Sciences and Pittsburgh NMR Center for Biomedical Research, Carnegie Mellon University, and the Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    J Thorac Cardiovasc Surg 120:923-34. 2000
    ..Although various techniques have been explored for the detection and quantification of allograft transplant rejection, a practical and reliable method that is noninvasive is still elusive...
  6. ncbi request reprint Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats
    S Kanno
    Department of Biological Sciences and Pittsburgh NMR Center for Biomedical Research, Carnegie Mellon University, Pittsburgh, PA 15213 2683, USA
    Circulation 104:945-50. 2001
    ..Endothelial nitric oxide synthase (eNOS) has also been shown to be protective by its vasodilatory effect. Therefore, we investigated whether expression of p21 and eNOS was modulated by ACEI treatment in a rat model...
  7. ncbi request reprint Association of intraluminal thrombus in abdominal aortic aneurysm with local hypoxia and wall weakening
    D A Vorp
    Department of Surgery, University of Pittsburgh, PA, USA
    J Vasc Surg 34:291-9. 2001
    ..The purpose of this work was to investigate this possibility...