Research Topics
| Luke P LeeSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
An integrated optofluidic platform for Raman-activated cell sortingAdrian Y Lau
Applied Physics and Biophysics Division, Lawrence Livermore National Laboratory, P O Box 808, L 211, Livermore, CA 94550, USA
Lab Chip 8:1116-20. 2008..This functional prototype lays the foundation for the development of a label-free cell sorting platform based on intrinsic Raman markers for automated sampling and sorting of a large number of individual cells in solution...
Label-free electrophysiological cytometry for stem cell-derived cardiomyocyte clustersFrank B Myers
Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Lab Chip 13:220-8. 2013..This is an entirely new approach to cell cytometry, in which a cell's functionality is assessed rather than its expression profile or physical characteristics...- Satellite nanoscope and cellular BioASICs for quantitative biomedicineLuke P Lee
Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Conf Proc IEEE Eng Med Biol Soc 2009:4582-5. 2009.... 
Inspirations from biological optics for advanced photonic systemsLuke P Lee
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, CA 94720 1762, USA
Science 310:1148-50. 2005..This is in part due to the availability of polymers with customizable optical properties and the ability to rapidly fabricate complex designs using soft lithography and three-dimensional microscale processing techniques...- Single-cell electroporation arrays with real-time monitoring and feedback controlMichelle Khine
School of Engineering, University of California, Merced, CA, USA
Lab Chip 7:457-62. 2007.... - Open-access microfluidic patch-clamp array with raised lateral cell trapping sitesAdrian Y Lau
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California-Berkeley, Berkeley, CA 94720, USA
Lab Chip 6:1510-5. 2006..The results demonstrate that the system is capable of performing whole cell measurements and drug profiling in a more efficient manner than the traditional patch-clamp set-up... - Biologically inspired artificial compound eyesKi-Hun Jeong
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, 485 Evans Hall No. 1762, University of California, Berkeley, CA 94720, USA
Science 312:557-61. 2006..The angular acceptance is directly measured by three-dimensional optical sectioning with a confocal microscope, and the detailed optical characteristics are studied in comparison with a natural compound eye... - A novel high aspect ratio microfluidic design to provide a stable and uniform microenvironment for cell growth in a high throughput mammalian cell culture arrayPaul J Hung
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, California, USA
Lab Chip 5:44-8. 2005.... - An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culturePhilip J Lee
Department of Bioengineering, Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, University of California Berkeley, Berkeley, CA 94720 1762, USA
Biotechnol Bioeng 97:1340-6. 2007..Experiments with the metabolism mediated liver toxicant diclofenac showed no hepatotoxicity after 4 h and an IC(50) of 334 +/- 41 microM after 24 h... - Comparison of near- and far-field measures for plasmon resonance of metallic nanoparticlesBenjamin M Ross
Department of Bioengineering, Applied Science and Technology Graduate Group, Biomolecular Nanotechnology Center, University of Calfornia Berkeley, Berkeley, CA 94720, USA
Opt Lett 34:896-8. 2009..We expect that taking into account these differences can provide improvement in understanding and optimizing surface-enhanced spectroscopies... - Creating high density nanoantenna arrays via plasmon enhanced particle-cavity (PEP-C) architecturesBenjamin M Ross
Biomolecular Nanotechnology Center, Department of Bioengineering, University of California Berkeley, Berkeley, CA 94720, USA
Opt Express 17:6860-6. 2009..These properties make the PEP-C antenna an excellent candidate for plasmonic-based biomolecular sensors... - Time-resolved optical sensing of oligonucleotide hybridization via Au colloidal nanoparticlesGang L Liu
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California at Berkeley, Berkeley, CA 94720, USA
J Nanosci Nanotechnol 5:1933-7. 2005..The approach presented in this paper extends the application of Au nanoparticles as the optical probe in oligonucleotide recognitions without prior sample labeling... - Nanoliter scale microbioreactor array for quantitative cell biologyPhilip J Lee
Department of Bioengineering, Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, University of California, Berkeley, 485 Evans Hall, 94720-1762, USA
Biotechnol Bioeng 94:5-14. 2006.... - Microfluidic alignment of collagen fibers for in vitro cell culturePhilip Lee
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, CA, USA
Biomed Microdevices 8:35-41. 2006..The use of artificially aligned collagen gels could be applied to the study of cell movement, signaling, growth, and differentiation... - Self-assembled three-dimensional nanocrown arraySoongweon Hong
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California at Berkeley, Berkeley, California 94720, United States
ACS Nano 6:5803-8. 2012..Because of its tunable size (i.e., 50 nm core and 20 nm satellite GNPs), arrangement, and periodicity, the nanocrown array shows multiple optical resonance frequencies at visible wavelengths as well as angle-dependent optical properties... - Omnidirectional 3D nanoplasmonic optical antenna array via soft-matter transformationBenjamin M Ross
Applied Science and Technology Graduate Group, Biomolecular Nanotechnology Center, University of California Berkeley, Berkeley, California 94720, United States
Nano Lett 11:2590-5. 2011..In addition, the macroscale morphology can be independently manipulated into arbitrary three-dimensional geometries, demonstrated with the fabrication of an omnidirectional nanoplasmonic optical antenna array... - Dynamic single cell culture arrayDino Di Carlo
Berkeley Sensor and Actuator Center, Biomolecular Nanotechnology Center, Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Lab Chip 6:1445-9. 2006..We anticipate uses in single cell analysis of drug toxicity with physiologically relevant perfused dosages as well as investigation of cell signaling pathways and systems biology... - Microfluidic self-assembly of tumor spheroids for anticancer drug discoveryLiz Y Wu
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Biomed Microdevices 10:197-202. 2008..A large amount of tumor spheroids (7,500 spheroids per square centimeter) with a narrow size distribution (10 +/- 1 cells per spheroid) can be formed in the device to provide a good platform for anticancer drug assays... - Shrinky-Dink microfluidics: 3D polystyrene chipsChi Shuo Chen
School of Engineering, University of California, Merced, USA
Lab Chip 8:622-4. 2008..Design conception to fully functional chips can thus be completed within minutes... - Peptide-nanoparticle hybrid SERS probes for optical detection of protease activityGang L Liu
Department of Bioengineering, Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, University of California, Berkeley, CA 94720, USA
J Nanosci Nanotechnol 7:2323-30. 2007.... - Peptide-nanoparticle hybrid SERS probe for dynamic detection of active cancer biomarker enzymesGang L Liu
Department of Bioengineering, University of California at Berkeley, CA 94720, USA
Conf Proc IEEE Eng Med Biol Soc 1:795-8. 2006..Peptide-conjugated nanocrescents should also be applicable for measuring the intercellular and intracellular activity of other cancer-related proteases and protease activity profiling-enabled cancer cell identification... - Additional amplifications of SERS via an optofluidic CD-based platformDukhyun Choi
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California at Berkeley, Berkeley, California 94720, USA
Lab Chip 9:239-43. 2009..The uniform SERS signals from different positions in spots of 3 mm2 on the different CDs gives us confidence in the reliability and stability of our SERS substrates... - On-chip cell lysis by local hydroxide generationDino Di Carlo
Department of Bioengineering, University of California at Berkeley, Berkeley, CA, USA
Lab Chip 5:171-8. 2005..The flow rate dependence of hydroxide concentration at the lysis filter is modeled and lysis efficiency is experimentally determined to be proportional to the hydroxide concentration for flow rates from 15 to 30 microl min(-1)... - Biologically functional cationic phospholipid-gold nanoplasmonic carriers of RNASomin Eunice Lee
Biomolecular Nanotechnology Center, Department of Bioengineering, University of California Berkeley, UCSF UCB Joint Graduate Group in Bioengineering, Berkeley, California 94720 1762, USA
J Am Chem Soc 131:14066-74. 2009.... - Nanophotonic crescent moon structures with sharp edge for ultrasensitive biomolecular detection by local electromagnetic field enhancement effectYu Lu
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California-Berkeley, Berkeley, California 94720, USA
Nano Lett 5:119-24. 2005.... - Optofluidic control using photothermal nanoparticlesGang L Liu
Biomolecular Nanotechnology Center, Department of Bioengineering, University of California at Berkeley, Berkeley, California 94720, USA
Nat Mater 5:27-32. 2006..Instead, our optofluidic control method will allow the fabrication of all-optical large-scale integrated microfluidic circuits for biomolecular and cellular processing without any physical valve or mechanical pumping device... - Single-cell level co-culture platform for intercellular communicationSoongweon Hong
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California at Berkeley, Berkeley, California 94720, USA
Integr Biol (Camb) 4:374-80. 2012..This study demonstrates the platform utility in providing a detailed and quantitative understanding of the complexity of cellular communication and its effects on cell behaviour in a variety of biological systems... - Non-invasive microfluidic gap junction assaySisi Chen
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California Berkeley, 408C Stanley Hall, CA 94720 1762, USA
Integr Biol (Camb) 2:130-8. 2010..This integrated microfluidic platform enables the in situ monitoring of gap junction communication, yielding dynamic information about intercellular molecular transfer and pharmacological inhibition and recovery... - Microfluidic environment for high density hepatocyte cultureMimi Y Zhang
UCSF UC Berkeley Joint Graduate Group in Bioengineering, Berkeley, CA, USA
Biomed Microdevices 10:117-21. 2008..Human hepatoma cells (HepG2/C3A) remained viable and functional as demonstrated by fluorescent viability assays and secretion of albumin for the one-week culture period... - Plasmon resonance energy transfer (PRET)-based molecular imaging of cytochrome c in living cellsYeonho Choi
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California at Berkeley, Berkeley, California 94720, USA
Nano Lett 9:85-90. 2009..As a first demonstration of in vivo PRET imaging, we performed a visualization of the dynamics of intracellular cytochrome c in HepG2 cells under ethanol-induced apoptosis... - A real-time PCR antibiogram for drug-resistant sepsisJohn R Waldeisen
Department of Bioengineering, University of California, Berkeley, California, United States of America
PLoS ONE 6:e28528. 2011..The real-time PCR antibiogram achieves detection, susceptibility testing, minimum inhibitory concentration determination, and identification in less than 24 hours... - Mammalian electrophysiology on a microfluidic platformCristian Ionescu-Zanetti
Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Proc Natl Acad Sci U S A 102:9112-7. 2005..1 in mammalian cells compare well with traditional pipette recordings. The results make possible the integration of whole-cell electrophysiology with easily manufactured microfluidic lab-on-a-chip devices... - Alkaline hemolysis fragility is dependent on cell shape: results from a morphology trackerCristian Ionescu-Zanetti
Bioengineering Department, University of California at Berkeley, Berkeley, California 94720, USA
Cytometry A 65:116-23. 2005..However, no quantitative data are available for changes in the morphology of individual cells during membrane poration-driven hemolysis or for the relation between cell shape and fragility... - Disassembly of a core-satellite nanoassembled substrate for colorimetric biomolecular detectionJohn R Waldeisen
UC Berkeley UCSF Graduate Program in Bioengineering and Department of Bioengineering, Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, University of California, Berkeley, California 94720, USA
ACS Nano 5:5383-9. 2011..This colorimetric substrate may prove to be a favorable alternative to liquid-based colloidal sensors and a useful visual readout mechanism for point-of-care microfluidic diagnostic assays... - Artificial ommatidia by self-aligned microlenses and waveguidesJaeyoun Kim
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, Berkeley, California 94720, USA
Opt Lett 30:5-7. 2005..75 degrees acceptance angle that is comparable to those found in nature. Using geometric and physical optics, we also investigate the relationship between angular sensitivity and the geometry of artificial ommatidia... - Shrinky-Dink microfluidics: rapid generation of deep and rounded patternsAnthony Grimes
School of Engineering, University of California, Merced, USA
Lab Chip 8:170-2. 2008..Finally, we demonstrate the utility of this simple microfabrication approach by fabricating a functional gradient generator. The whole process--from device design conception to working device--can be completed within minutes... - Stimulation and artifact-free extracellular electrophysiological recording of cells in suspensionFrank B Myers
Department of Bioengineering, University of California, Berkeley, CA, USA
Conf Proc IEEE Eng Med Biol Soc 2011:4030-3. 2011..Finally, we explain the relationship between extracellular field potentials and the more familiar transmembrane action potential signal, noting the physiologically important features of these signals... - Integrated microfluidic cell culture and lysis on a chipJ Tanner Nevill
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, UCSF UCB Joint Graduate Group in Bioengineering, Berkeley, CA, USA
Lab Chip 7:1689-95. 2007..Sample proteins exposed to the electrochemical lysis conditions were immunodetectable (p53) and their enzymatic activity (HRP) was investigated... - Generation of monodisperse silk microspheres prepared with microfluidicsDavid N Breslauer
UCSF UC Berkeley Bioengineering Graduate Group, Department of Bioengineering, University of California, Berkeley, Berkeley, California 94720, USA
Biomacromolecules 11:643-7. 2010..Because silk is well established as biocompatible and biodegradable, we anticipate that these silk microspheres could have particular utility in drug delivery and controlled release... - Engineered approaches to the stem cell microenvironment for cardiac tissue regenerationEbrahim Ghafar-Zadeh
Department of Bioengineering, University of California, Berkeley, USA
Lab Chip 11:3031-48. 2011.... - Continuous perfusion microfluidic cell culture array for high-throughput cell-based assaysPaul J Hung
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, 485 Evans Hall, Berkeley, CA 94720, USA
Biotechnol Bioeng 89:1-8. 2005..The cell culture array could offer a platform for a wide range of assays with applications in drug screening, bioinformatics, and quantitative cell biology... - Biomolecular plasmonics for quantitative biology and nanomedicineSomin Eunice Lee
Department of Bioengineering, University of California Berkeley, UCSF UCB Joint Graduate Group in Bioengineering, Berkeley Sensor and Actuator Center, Berkeley, CA, USA
Curr Opin Biotechnol 21:489-97. 2010..Nanoplasmonic molecular rulers and integrated photoacoustic-photothermal contrast agents are also described... - A single cell electroporation chipMichelle Khine
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Lab Chip 5:38-43. 2005.... - Label-free and highly sensitive biomolecular detection using SERS and electrokinetic preconcentrationHansang Cho
Biomolecular Nanotechnology Center, Department of Bioengineering, University of California, Berkeley, California 94720, USA
Lab Chip 9:3360-3. 2009..6 V cm(-1) after 25 min. The effectiveness of this method allows the creation of label-free, target-specific, and highly sensitive monitoring applications... - Remote optical switch for localized and selective control of gene interferenceSomin Eunice Lee
Department of Bioengineering, University of California Berkeley, CA, USA
Nano Lett 9:562-70. 2009..We demonstrate a novel gene-interfering technique offering spatial and temporal control, which is otherwise impossible using conventional gene-interfering techniques... - Dynamic single-cell analysis for quantitative biologyDino Di Carlo
Department of Bioengineering, University of California-Berkeley, Berkeley, CA 94720, USA
Anal Chem 78:7918-25. 2006 - Single-cell enzyme concentrations, kinetics, and inhibition analysis using high-density hydrodynamic cell isolation arraysDino Di Carlo
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, California 94720, USA
Anal Chem 78:4925-30. 2006..For HeLa cells, 20 nM of the 50 nM total carboxylesterases was unaffected by NDGA. This type of analysis could be directly applied to quantify a variety of intracellular enzymes with available fluorogenic substrates... - Innovations in optical microfluidic technologies for point-of-care diagnosticsFrank B Myers
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Lab Chip 8:2015-31. 2008..We also examine several emerging detection paradigms involving nanoengineered materials which do not suffer from the same miniaturization disadvantages as conventional measurements... - Nanowire-based single-cell endoscopyRuoxue Yan
Department of Chemistry, University of California, and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
Nat Nanotechnol 7:191-6. 2012..Moreover, insertion of the endoscope into cells and illumination of the guided laser did not induce any significant toxicity in the cells... - A point-of-care instrument for rapid multiplexed pathogen genotypingFrank B Myers
Department of Bioengineering, University of California, Berkeley, CA, USA
Conf Proc IEEE Eng Med Biol Soc 2011:3668-71. 2011..The platform can be tailored for different economic situations--from a quantitative electronic readout to a simple binary readout with the naked eye... - Photonic gene circuits by optically addressable siRNA-Au nanoantennasSomin Eunice Lee
UCSF UCB Joint Graduate Group in Bioengineering, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California Berkeley, Berkeley, California, United States
ACS Nano 6:7770-80. 2012..Photonic gene circuits open new avenues for engineering functional gene circuits useful for fundamental bioscience, bioengineering, and medical applications... - Single-step nanoplasmonic VEGF165 aptasensor for early cancer diagnosisHansang Cho
Berkeley Sensor and Actuator Center, Department of Bioengineering, Department of Electrical Engineering and Computer Science, University of California, Berkeley, California 94720, United States
ACS Nano 6:7607-14. 2012..We envision that our developed aptasensor holds utilities for point-of-care cancer prognostics by incorporating simplicity in detection, low-cost for test, and required small sample volumes... - Quantized plasmon quenching dips nanospectroscopy via plasmon resonance energy transferGang Logan Liu
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California Berkeley, 442 Stanley Hall, Berkeley, California 94720, USA
Nat Methods 4:1015-7. 2007..This label-free biomolecular absorption nanospectroscopic method has ultrahigh molecular sensitivity... - Microfluidics-based systems biologyDavid N Breslauer
UCSF/UC Berkeley Bioengineering Graduate Group, Department of Bioengineering, University of California Berkeley, Berkeley, CA, USA
Mol Biosyst 2:97-112. 2006.... - Micropatterned hot-embossed polymeric surfaces influence cell proliferation and alignmentLorenzo Moroni
Department of Bioengineering, University of California Berkeley, 459 Evans Hall No 1762, UC Berkeley, Berkeley, California 94720 1762, USA
J Biomed Mater Res A 88:644-53. 2009..These findings could be useful in tissue engineering applications where higher proliferation rates and eventual random or unidimensional alignments of cells are desirable... - Nanoplasmonic gene regulationSomin Eunice Lee
Department of Bioengineering, University of California Berkeley, UCSF UCB Joint Graduate Group in Bioengineering, Berkeley Sensor and Actuator Center, Berkeley, CA, USA
Curr Opin Chem Biol 14:623-33. 2010.... - High-density silver nanoparticle film with temperature-controllable interparticle spacing for a tunable surface enhanced Raman scattering substrateYu Lu
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California Berkeley, Berkeley, California 94720, USA
Nano Lett 5:5-9. 2005..The SERS spectra of Rhodamine 6G on a high-density silver particle film at various temperatures is characterized to demonstrate the tunable plasmon coupling between high-density nanoparticles... - Simulation of flow in the silk glandDavid N Breslauer
UCSF UC Berkeley Bioengineering Graduate Group, Bionanotechnology Center, and Department of Chemical Engineering, University of California, Berkeley, Berkeley, California, USA
Biomacromolecules 10:49-57. 2009..These results provide new insight into silk spinning processes and will guide the future development of novel fiber spinning technologies... - Theoretical and experimental study towards a nanogap dielectric biosensorMingqiang Yi
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California at Berkeley, Berkeley, CA 94720-1762, USA
Biosens Bioelectron 20:1320-6. 2005..A capacitance change of a 20 nm x (10)1.5 microm x 4mm gap from 3.5 to 4.1 nF at 200 Hz was recorded between deionized water (DI) and 100 nM ssDNA solution (about 70,000 molecules inside the gap for equilibrium state)... - Optical properties of the crescent-shaped nanohole antennaLiz Y Wu
Applied Science and Technology Graduate Group, Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, and Department of Bioengineering, University of CaliforniaBerkeley, Berkeley, California 94720
Nano Lett 9:1956-61. 2009.... - Plasmon tuning and local field enhancement maximization of the nanocrescentBenjamin M Ross
Applied Science and Technology Graduate Group, Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California Berkeley, Berkeley, CA 94720, USA
Nanotechnology 19:275201. 2008.... - Biomimetic technique for adhesion-based collection and separation of cells in a microfluidic channelWesley C Chang
Berkeley Sensor and Actuator Center, University of California, Berkeley, 94720, USA
Lab Chip 5:64-73. 2005..Additionally, among collected cells, the difference in flow-driven, adhesion-mediated cell transit in the Square design suggested that the two cell types could at least be partially fractionated... - Reagentless mechanical cell lysis by nanoscale barbs in microchannels for sample preparationDino Di Carlo
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Lab Chip 3:287-91. 2003..At a flow rate of 300 microL min(-1) within the filter region total protein and hemoglobin accessibilities of 4.8% and 7.5% are observed respectively as compared to 1.9% and 3.2% for a filter without nanostructured barbs... - Aptamer-based SERRS sensor for thrombin detectionHansang Cho
Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, California 94720, USA
Nano Lett 8:4386-90. 2008..Furthermore, the proposed sensor may be implemented for multiplexed detection using different aptamer-Raman probe complexes... - Micromachined transmissive scanning confocal microscopeSunghoon Kwon
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, California 94720, USA
Opt Lett 29:706-8. 2004..We have demonstrated reflection confocal imaging with 3-microm transverse resolution over a 100-microm field of view and a 0.38-mm working distance at lambda = 633 nm... - Total internal reflection-based biochip utilizing a polymer-filled cavity with a micromirror sidewallNikolas Chronis
Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, USA
Lab Chip 4:125-30. 2004..The proposed TIR-based chip simplifies current TIR optical configurations and could potentially be used as an optical-microfluidic platform for an integrated lab-on-a-chip microsystem... - A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprintingGang L Liu
Nat Nanotechnol 1:47-52. 2006 - Sample concentration and impedance detection on a microfluidic polymer chipPoorya Sabounchi
Energy Systems Department, Sandia National Laboratories, Livermore, CA, USA
Biomed Microdevices 10:661-70. 2008....