L A Lee

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Photosensitivity diseases: cutaneous lupus erythematosus
    L A Lee
    Department of Medicine, Denver Health Medical Center, Colorado, USA
    J Investig Dermatol Symp Proc 4:73-8. 1999
  2. ncbi request reprint Neonatal lupus: clinical features, therapy, and pathogenesis
    L A Lee
    Department of Dermatology, University of Colorado School of Medicine, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Curr Rheumatol Rep 3:391-5. 2001
  3. ncbi request reprint Characterization of an autoantigen associated with chronic ulcerative stomatitis: the CUSP autoantigen is a member of the p53 family
    L A Lee
    Department of Medicine, Denver Health Medical Center, Colorado, USA
    J Invest Dermatol 113:146-51. 1999
  4. ncbi request reprint Behçet disease
    L A Lee
    Department of Dermatology, University of Colorado School of Medicine, Denver, USA
    Semin Cutan Med Surg 20:53-7. 2001
  5. ncbi request reprint Neonatal lupus erythematosus: clinical findings and pathogenesis
    Lela A Lee
    University of Colorado School of Medicine, Denver Health Medical Center, Denver, Colorado 80204, USA
    J Investig Dermatol Symp Proc 9:52-6. 2004
  6. ncbi request reprint Hepatobiliary disease in neonatal lupus: prevalence and clinical characteristics in cases enrolled in a national registry
    Lela A Lee
    Departments of Dermatology and Medicine, University of Colorado School of Medicine, and Department of Medicine, Denver Health Medical Center, Denver, Colorado, USA
    Pediatrics 109:E11. 2002
  7. ncbi request reprint Transient autoimmunity related to maternal autoantibodies: neonatal lupus
    Lela A Lee
    Dermatology Service, Department of Medicine, Denver Health Medical Center, 660 Bannock, Mail Code 4000, Denver, CO 80204, United States
    Autoimmun Rev 4:207-13. 2005
  8. ncbi request reprint CUSP/p63 expression in rat and human tissues
    R P Dellavalle
    Department of Dermatology, University of Colorado School of Medicine, B 153, 4200 E Ninth Avenue, Denver, CO 90262, USA
    J Dermatol Sci 27:82-7. 2001
  9. pmc Pattern of cutaneous immunoglobulin G deposition in subacute cutaneous lupus erythematosus is reproduced by infusing purified anti-Ro (SSA) autoantibodies into human skin-grafted mice
    L A Lee
    Department of Dermatology, University of Colorado School of Medicine, Denver 80262
    J Clin Invest 83:1556-62. 1989
  10. ncbi request reprint Unilateral tumid lupus erythematosus
    T R Pacheco
    Lupus 11:388-91. 2002

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Photosensitivity diseases: cutaneous lupus erythematosus
    L A Lee
    Department of Medicine, Denver Health Medical Center, Colorado, USA
    J Investig Dermatol Symp Proc 4:73-8. 1999
    ..Recent advances in phototesting and analysis of the genetics of lupus should clarify the events leading to photosensitive cutaneous lupus lesions...
  2. ncbi request reprint Neonatal lupus: clinical features, therapy, and pathogenesis
    L A Lee
    Department of Dermatology, University of Colorado School of Medicine, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Curr Rheumatol Rep 3:391-5. 2001
    ..While often initially asymptomatic, mothers tend to develop symptoms of connective tissue disease. This review discusses the recent advances in the understanding of neonatal lupus, its clinical features, therapy, and pathogenesis...
  3. ncbi request reprint Characterization of an autoantigen associated with chronic ulcerative stomatitis: the CUSP autoantigen is a member of the p53 family
    L A Lee
    Department of Medicine, Denver Health Medical Center, Colorado, USA
    J Invest Dermatol 113:146-51. 1999
    ..The p53-like genes, p73 and the several KET splicing variants, are recently described genes of uncertain biologic and pathologic significance. This study provides the first clear association of a p53-like protein with a disease process...
  4. ncbi request reprint Behçet disease
    L A Lee
    Department of Dermatology, University of Colorado School of Medicine, Denver, USA
    Semin Cutan Med Surg 20:53-7. 2001
    ..There is considerable morbidity resulting from Behçet's disease, most notably a high risk of blindness from ocular involvement. Mortality may occur as a result of neurologic or vascular disease or gastrointestinal perforation...
  5. ncbi request reprint Neonatal lupus erythematosus: clinical findings and pathogenesis
    Lela A Lee
    University of Colorado School of Medicine, Denver Health Medical Center, Denver, Colorado 80204, USA
    J Investig Dermatol Symp Proc 9:52-6. 2004
    ..Only a minority of babies exposed to the autoantibodies develop disease, however, and mothers and their babies have different disease manifestations. Thus, additional factors are likely to be important in determining disease expression...
  6. ncbi request reprint Hepatobiliary disease in neonatal lupus: prevalence and clinical characteristics in cases enrolled in a national registry
    Lela A Lee
    Departments of Dermatology and Medicine, University of Colorado School of Medicine, and Department of Medicine, Denver Health Medical Center, Denver, Colorado, USA
    Pediatrics 109:E11. 2002
    ..To extend the information base on the hepatobiliary manifestations of neonatal lupus erythematosus (NLE) with regard to frequency of occurrence, clinical characteristics, and outcome...
  7. ncbi request reprint Transient autoimmunity related to maternal autoantibodies: neonatal lupus
    Lela A Lee
    Dermatology Service, Department of Medicine, Denver Health Medical Center, 660 Bannock, Mail Code 4000, Denver, CO 80204, United States
    Autoimmun Rev 4:207-13. 2005
    ..In this review the clinical features, diagnosis, therapy, and prognosis of NLE are discussed, and a summary of experimental data relating to pathogenesis is presented...
  8. ncbi request reprint CUSP/p63 expression in rat and human tissues
    R P Dellavalle
    Department of Dermatology, University of Colorado School of Medicine, B 153, 4200 E Ninth Avenue, Denver, CO 90262, USA
    J Dermatol Sci 27:82-7. 2001
    ..Focal p63 expression within tissues, the complex array of isoforms encoded by the gene, and the specificity of the probes and antibodies utilized, may all contribute to contradictory accounts of CUSP/p63 expression...
  9. pmc Pattern of cutaneous immunoglobulin G deposition in subacute cutaneous lupus erythematosus is reproduced by infusing purified anti-Ro (SSA) autoantibodies into human skin-grafted mice
    L A Lee
    Department of Dermatology, University of Colorado School of Medicine, Denver 80262
    J Clin Invest 83:1556-62. 1989
    ..These data directly show that anti-Ro (SSA) antibodies bind to the skin, and support the hypothesis that anti-Ro (SSA) autoantibodies are involved in the disease process that produces subacute cutaneous lupus and neonatal lupus...
  10. ncbi request reprint Unilateral tumid lupus erythematosus
    T R Pacheco
    Lupus 11:388-91. 2002
    ..We report a case of blaschkolinear cutaneous tumid lupus erythematous and discuss the potential association between cutaneous genetic mosaicism, Blaschko lines and lupus susceptibility...
  11. doi request reprint Cutaneous lupus in infancy and childhood
    L A Lee
    Dermatology Service, Denver Health Medical Center, Denver, CO 80204, USA
    Lupus 19:1112-7. 2010
    ..In this review, clinical findings, diagnosis, management, and pathogenesis of neonatal lupus are discussed, and the management of cutaneous lupus in children is detailed...
  12. pmc Comparison of the reliability and validity of outcome instruments for cutaneous dermatomyositis
    R Q Klein
    Department of Dermatology, School of Medicine, University of Pennsylvania, 3600 Spruce Street, 2 Maloney Building, Philadelphia, PA 19104, USA
    Br J Dermatol 159:887-94. 2008
    ..Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), Dermatomyositis Skin Severity Index (DSSI) and Cutaneous Assessment Tool (CAT) skin indices have been developed as outcome instruments...
  13. ncbi request reprint Endoscopic findings predict the histologic diagnosis in gastrointestinal graft-versus-host disease
    M Cruz-Correa
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Endoscopy 34:808-13. 2002
    ..We performed a study to determine the diagnostic accuracy of macroscopic endoscopy findings in the diagnosis of acute and chronic histologically proven gastrointestinal GvHD (GI-GvHD)...
  14. ncbi request reprint Myc target transcriptomes
    L A Lee
    Department of Medicine, The Johns Hopkins University School of Medicine, Ross 1032, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Curr Top Microbiol Immunol 302:145-67. 2006
    ....
  15. ncbi request reprint Dermatology position paper on the revision of the 1982 ACR criteria for systemic lupus erythematosus
    J Albrecht
    Department of Dermatology, University of Pennsylvania, PA, USA
    Lupus 13:839-49. 2004
    ..In order to demonstrate specificity of the criteria with a 95% confidence interval between 90 and 100%, each control group of the above should have at least 73 patients...
  16. ncbi request reprint Autoantibodies in mothers of children with neonatal liver disease
    Joanna M Burch
    Department of Dermatology, University of Colorado School of Medicine, CO, USA
    J Pediatr Gastroenterol Nutr 37:262-7. 2003
    ..This study was performed to determine whether idiopathic neonatal cholestasis (INC) represents NLE without its cardiac or cutaneous findings...
  17. ncbi request reprint CUSP/p63 expression in basal cell carcinoma
    Robert P Dellavalle
    Department of Dermatology, University of Colorado School of Medicine, Denver, Colorado, USA
    Exp Dermatol 11:203-8. 2002
    ..Therefore, CUSP appears to be present, unmutated, and yet frequently undetectable by immunofluorescence in cutaneous lesions in both humans and mice that are associated with SHH pathway dysregulation (BCCs, BCNS, and nevus sebaceous)...
  18. ncbi request reprint Neonatal lupus erythematosus
    Joanna M Burch
    University of Colorado Health Sciences Center, Denver, CO, USA
    Dermatol Nurs 14:157-60. 2002
    ..Mothers of babies with NLE are likely to develop collagen vascular diseases with time. Infants with NLE are at risk to develop other autoimmune diseases during childhood or adolescence...
  19. ncbi request reprint Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis
    Robert M Clancy
    Department of Rheumatology, Hospital for Joint Diseases, New York University School of Medicine, New York, New York 10003, USA
    Arthritis Rheum 50:2598-603. 2004
    ..Accordingly, this study was undertaken to seek genetic and histologic evidence for a role of TNFalpha in the pathogenesis of cutaneous neonatal lupus...
  20. ncbi request reprint Neonatal lupus: clinical features and management
    Lela A Lee
    Denver Health Medical Center, Denver, CO 80204, USA
    Paediatr Drugs 6:71-8. 2004
    ..About half of the mothers are asymptomatic at the time of presentation of the child, but some of these women eventually develop symptoms of autoimmune disease...
  21. ncbi request reprint deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes
    Kathryn E King
    Center for Biologics Evaluation and Research, FDA, Bethesda, MD 20892, USA
    Oncogene 22:3635-44. 2003
    ..These findings support deltaNp63alpha as a master regulator of keratinocyte differentiation, and suggest a novel function of this protein in the maintenance of epithelial homeostasis...
  22. ncbi request reprint The CUSP DeltaNp63alpha isoform of human p63 is downregulated by solar-simulated ultraviolet radiation
    Angela Marchbank
    Department of Dermatology, University of Colorado School of Medicine, Denver, CO, USA
    J Dermatol Sci 32:71-4. 2003
    ..The significant constitutive expression of DeltaNp63alpha in stratified epithelium has been proposed to maintain the proliferative capacity of basal cells, blocking the consequences of inappropriate p53 activation...
  23. ncbi request reprint Long-term followup of children with neonatal lupus and their unaffected siblings
    Victor Martin
    Hospital for Joint Diseases, New York University School of Medicine, New York, New York 10003, USA
    Arthritis Rheum 46:2377-83. 2002
    ..To determine in a longitudinal cohort study whether children with varied manifestations of neonatal lupus or their unaffected siblings later develop autoantibodies and/or rheumatic diseases...