Research Topics
| Hanmin LeeSummaryAffiliation: University of California Country: USA Publications
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Publications
Efficacy of radiofrequency ablation for twin-reversed arterial perfusion sequenceHanmin Lee
Fetal Treatment Center and the Department of Surgery, University of California, San Francisco, San Francisco, CA 94143 0570, USA
Am J Obstet Gynecol 196:459.e1-4. 2007..We report our experience in the treatment of patients with twin-reversed arterial perfusion (TRAP) sequence using radiofrequency ablation to stop perfusion to the acardiac twin and protect the pump twin...- Effect of implantation site on hepatocytes heterotopically transplanted on biodegradable polymer scaffoldsHanmin Lee
Department of Surgery, University of California at San Francisco, San Francisco, California 94143, USA
Tissue Eng 9:1227-32. 2003..The omentum is the most favorable bed for engraftment of hepatocyte-polymer tissue-engineered constructs and the addition of a portacaval shunt increases survival of transplanted hepatocytes in the omentum and mesentery... 
Long-term surgical outcomes in congenital diaphragmatic hernia: observations from a single institutionTim Jancelewicz
Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, CA 94143, USA
J Pediatr Surg 45:155-60; discussion 160. 2010..Surgical complications are common in survivors of congenital diaphragmatic hernia (CDH), but little is known about long-term incidence patterns and associated predictors...- Long-term outcomes after fetal therapy for congenital high airway obstructive syndromePayam Saadai
Division of Pediatric Surgery and Fetal Treatment Center, Department of Surgery, University of California, Box 0570, San Francisco, CA 94143 0570, USA
J Pediatr Surg 47:1095-100. 2012..Congenital high airway obstructive syndrome (CHAOS) is a rare and devastating condition that is uniformly fatal without fetal intervention. We sought to describe fetal treatment and long-term outcomes of CHAOS at a single referral center... - Reliability of the lung-to-head ratio as a predictor of outcome in fetuses with isolated left congenital diaphragmatic hernia at gestation outside 24-26 weeksSoon Ha Yang
Fetal Treatment Center, University of California, San Francisco, San Francisco, CA 94143 0570, USA
Am J Obstet Gynecol 197:30.e1-7. 2007.... - Does congenital diaphragmatic hernia associated with bronchopulmonary sequestration portend a better prognosis?Erich J Grethel
Department of Pediatric Surgery, University of California, San Francisco, CA 94143 0570, USA
Fetal Diagn Ther 23:250-3. 2008..We reviewed our experience to evaluate if prognosis was better in the CDH infants with associated bronchopulmonary sequestration... - The ex utero intrapartum treatment procedure: Looking back at the EXITShinjiro Hirose
Division of Pediatric Surgery and the Fetal Treatment Center, Department of Surgery, University of California, San Francisco, San Francisco, CA 94143-0570, USA
J Pediatr Surg 39:375-80; discussion 375-80. 2004..EXIT procedures have evolved from an adjunct to fetal surgery to a potentially life-saving procedure in fetuses with airway compromise at birth... - Prenatal steroids for microcystic congenital cystic adenomatoid malformationsPatrick F Curran
The Fetal Treatment Center, University of California San Francisco, San Francisco, CA, USA
J Pediatr Surg 45:145-50. 2010..The purpose of this study is to evaluate the effect of prenatal steroid treatment in fetuses with sonographically diagnosed congenital cystic adenomatoid malformations (CCAMs)... - Infant pulmonary function in a randomized trial of fetal tracheal occlusion for severe congenital diaphragmatic herniaRoberta L Keller
The Cardiovascular Research Institute and Department of Pediatrics, UCSF Box 0748, San Francisco, CA 94143, USA
Pediatr Res 56:818-25. 2004..We conclude that fetal TO for severe CDH results in modest improvements in neonatal pulmonary function that are of questionable clinical significance... - Long-term follow-up after thymectomy for myasthenia gravis: thoracoscopic vs openAmy J Wagner
Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, CA 94143, USA
J Pediatr Surg 41:50-4; discussion 50-4. 2006..The thoracoscopic group has the added benefits of decreased estimated blood loss, decreased length of hospital stay, and improved cosmesis. We advocate the thoracoscopic approach for thymectomy in the treatment of juvenile MG... - Monochorionic twin gestation complicated by a sacrococcygeal teratoma with hydrops--optimal timing of delivery allows for survival of the unaffected twinMarsha Ayzen
Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, CA 94143, USA
J Pediatr Surg 41:e11-3. 2006..In this case, serial ultrasound evaluations and timing of delivery optimized the outcome of the unaffected twin... - Thoracoscopic versus open resection for congenital cystic adenomatoid malformations of the lungLan T Vu
Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, CA 94131 0570, USA
J Pediatr Surg 43:35-9. 2008..This study evaluated the potential advantages of thoracoscopy compared to thoracotomy for resection of congenital cystic adenomatoid malformations (CCAM)... - Survival of severe congenital diaphragmatic hernia has morbid consequencesRaul A Cortes
Department of Surgery and Fetal Treatment Center, University of California in San Francisco Medical Center and Children's Hospital, San Francisco, CA 94143-0570, USA
J Pediatr Surg 40:36-45; discussion 45-6. 2005..Severe CDH carries significant risk of chronic morbidity... - Prosthetic patches for congenital diaphragmatic hernia repair: Surgisis vs Gore-TexErich J Grethel
Division of Pediatric Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
J Pediatr Surg 41:29-33; discussion 29-33. 2006..A recent trend has been toward the use of bioactive prosthetic materials. We reviewed different patch closure techniques used for CDH repair at our institution and their association with these sequelae... 
Alterations in maternal-fetal cellular trafficking after fetal surgeryPayam Saadai
Division of Pediatric Surgery and Fetal Treatment Center, Department of Surgery, University of California, San Francisco, CA 94143 0570, USA
J Pediatr Surg 47:1089-94. 2012..We hypothesized that patients undergoing open fetal surgery would have altered maternal-fetal cellular trafficking...- Echocardiographic risk stratification of fetuses with sacrococcygeal teratoma and twin-reversed arterial perfusionFrancesca A Byrne
Division of Cardiology, Department of Pediatrics, University of California San Francisco Benioff Children s Hospital, San Francisco, CA, USA
Fetal Diagn Ther 30:280-8. 2011.... - A randomized trial of fetal endoscopic tracheal occlusion for severe fetal congenital diaphragmatic herniaMichael R Harrison
Fetal Treatment Center, University of California, San Francisco, San Francisco, CA 94143-0570, USA
N Engl J Med 349:1916-24. 2003..37.0+/-1.5 weeks; P<0.001). The rates of neonatal morbidity did not differ between the groups. CONCLUSIONS: Tracheal occlusion did not improve survival or morbidity rates in this cohort of fetuses with congenital diaphragmatic hernia... - Determination of risk factors for deep venous thrombosis in hospitalized childrenLan T Vu
Division of Pediatric Surgery, Department of Surgery, University of California, Box 0570, San Francisco, CA 94143 0570, USA
J Pediatr Surg 43:1095-9. 2008..Our objective was to determine the time trend and risk factors for deep venous thrombosis (DVT) of the lower extremities among pediatric inpatients... - Spontaneous rupture of fetal sacrococcygeal teratomaEdgar D Sy
Fetal Treatment Center, University of California, San Francisco, Calif, USA
Fetal Diagn Ther 21:424-7. 2006..At 23 weeks, there was a sudden appearance of an additional lobular mass, consistent with intrauterine spontaneous ruptured of a sacrococcygeal teratoma mass... - Fetal intervention for mass lesions and hydrops improves outcome: a 15-year experienceErich J Grethel
Division of Pediatric Surgery, Fetal Treatment Center, University of California, San Francisco, San Francisco, CA 94143 0570, USA
J Pediatr Surg 42:117-23. 2007..However, hydrops associated with fetal mass lesions can be halted and even reversed with fetal intervention and treatment of the underlying defect. We examined our patients with fetal mass lesions to evaluate survival after intervention... - Surgical treatment of childhood recurrent pancreatitisMatthew S Clifton
Division of Pediatric Surgery, Department of Surgery, University of California San Francisco, Box 0570, San Francisco, CA 94143 0570, USA
J Pediatr Surg 42:1203-7. 2007..Surgical intervention that improves pancreatic ductal drainage is a reasonable treatment strategy for recurrent pancreatitis in children... - Resolution of hydrops fetalis in congenital cystic adenomatoid malformation after prenatal steroid therapyKuoJen Tsao
Fetal Treatment Center, Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, California 94143-0570, USA
J Pediatr Surg 38:508-10. 2003..Because the mechanism of this process is speculative, further studies are needed to elucidate the relationship between antenatal steroids and maturation of congenital cystic adenomatoid malformation... - Microcystic congenital pulmonary airway malformation with hydrops fetalis: steroids vs open fetal resectionKenneth C Loh
Department of Surgery, University of California at San Francisco, San Francisco, CA 94143 0570, USA
J Pediatr Surg 47:36-9. 2012..The presence of hydrops fetalis is an indicator of poor prognosis. Here we present a retrospective review of fetuses undergoing either open fetal surgery or steroids for predominantly microcystic CPAM with hydrops fetalis... - Characteristics of congenital cystic adenomatoid malformations associated with nonimmune hydrops and outcomeLan Vu
Fetal Treatment Center, Department of Pediatric Surgery, University of California, San Francisco, Box 0570, San Francisco, CA 94143 0570, USA
J Pediatr Surg 42:1351-6. 2007..This study attempts to (1) determine sonographic features (in addition to large size) that correlate with hydrops and (2) characterize the features that correlate with outcome among hydropic fetuses... - Local delivery of basic fibroblast growth factor increases both angiogenesis and engraftment of hepatocytes in tissue-engineered polymer devicesHanmin Lee
Department of Surgery, University of California at San Francisco, San Francisco, California 94143-0570, USA
Transplantation 73:1589-93. 2002..Implantation of these devices increases angiogenesis into the device and increases hepatocyte engraftment... - Maternal morbidity after maternal-fetal surgeryKirstin Golombeck
Division of Pediatric Surgery, Department of Surgery, The Fetal Treatment Center, University of California, San Francisco, CA 94143-0570, USA
Am J Obstet Gynecol 194:834-9. 2006..Maternal-fetal surgery can be performed without maternal death. Results from this study provide helpful data for counseling prospective patients... - Prevention of graft rejection by donor type II CD8(+) T cells (Tc2 cells) is not sufficient to improve engraftment in fetal transplantationJeng-Chang Chen
Fetal Treatment Center, Department of Surgery, University of California, San Francisco, CA 94143, USA
Fetal Diagn Ther 20:35-43. 2005..Donor cells can persist in the peritoneal cavity and might play an important role in inducing immune tolerance in fetuses... - The influence of portoenterostomy on transplantation for biliary atresiaBrendan C Visser
The University of California, San Francisco, CA, USA
Liver Transpl 10:1279-86. 2004..The 1-, 5-, and 10-year actuarial patient survival rates were 91%, 89%, and 83%. PE remains an important bridge to transplant. In conclusion, transplantation for BA offers excellent long-term graft and patient survival... - Thoracoscopic lobectomy for prenatally diagnosed lung lesionsCraig T Albanese
Division of Pediatric Surgery, Department of Surgery, and the Fetal Treatment Center, University of California, San Francisco, CA 94143-0570, USA
J Pediatr Surg 38:553-5. 2003..Thoracoscopic lobectomy is a relatively quick and safe procedure, and the cosmetic result is excellent. Early resection obviates the risk of infection in these lesions... - Prenatal diagnosis of familial type I choledochal cystMatthew S Clifton
Department of Surgery, University of California, San Francisco, CA 94143-0570, USA
Pediatrics 117:e596-600. 2006..We report an unusual occurrence of siblings with type I choledochal cysts and review the existing literature on cause, genetics, classification, diagnosis, and management of this disease... - Selective reduction of acardiac twin by radiofrequency ablationKuoJen Tsao
Fetal Treatment Center, Department of Surgery, University of California, San Francisco 94143-0570, USA
Am J Obstet Gynecol 187:635-40. 2002..2 weeks. CONCLUSION: Radiofrequency ablation is a minimally invasive, percutaneous technique that can effectively obliterate blood supply to an acardiac twin to preserve and protect the pump twin... - Comparison of drainage techniques for biliary atresiaKuoJen Tsao
Fetal Treatment Center, Department of Surgery, Division of Pediatric Surgery, San Francisco, CA 94143-0570, USA
J Pediatr Surg 38:1005-7. 2003..Although the appendix may serve as an alternative biliary conduit, traditional Kasai portoenterostomy appears to achieve better biliary drainage... - Sacrococcygeal teratoma with spinal canal invasion prenatally diagnosedEric Jelin
Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, CA 94143, USA
J Pediatr Surg 44:E9-11. 2009..We report a case of SCT invading the spinal canal seen on prenatal ultrasound. To our knowledge, this is the first documented case of prenatally diagnosed SCT intraspinal invasion... - Advances in prenatal diagnosis and treatment of congenital diaphragmatic herniaEveline H Shue
Division of Pediatric Surgery, Department of Surgery, Fetal Treatment Center University of California, San Francisco, 513 Parnassus Avenue, HSW 1601, San Francisco, CA 94143 0570, USA
Clin Perinatol 39:289-300. 2012..This article reviews advances in prenatal diagnosis of CDH, the experimental basis for tracheal occlusion, and its translation into human clinical trials... - The diagnosis and management of intradiaphragmatic extralobar pulmonary sequestrations: a report of 4 casesAmar Nijagal
Department of Surgery, University of California, San Francisco, CA 94143 0570, USA
J Pediatr Surg 47:1501-5. 2012..We report the largest series of patients with IDEPS and describe the diagnostic and operative challenges associated with this condition... - Tracheal occlusion for fetal congenital diaphragmatic hernia: the US experienceEric Jelin
Division of Pediatric Surgery, Department of Surgery, Fetal Treatment Center, University of California, San Francisco, CA 94143 0570, USA
Clin Perinatol 36:349-61, ix. 2009..This article reviews the experimental basis of fetal therapy for CDH and the US clinical experience with tracheal occlusion... - Long-term survival and renal transplantation in a monozygotic twin with cloacal dysgenesis sequenceRita A Mukhtar
Department of Surgery, University of California, San Francisco, CA 94143, USA
J Pediatr Surg 44:e31-3. 2009..Pediatr Dev Pathol 1998;1:281-288). We report a case of long-term survival, currently to 25 months of age, and renal transplantation in a monochorionic, diamniotic twin girl with CDS... - Fetoscopic transuterine release of posterior urethral valves: a new techniqueMatthew S Clifton
Fetal Treatment Center, University of California, San Francisco, San Francisco, CA 94143 0570, USA
Fetal Diagn Ther 23:89-94. 2008..The technique offers a minimal degree of maternal morbidity and, if instituted early enough, can restore amniotic fluid volume, avert fatal pulmonary hypoplasia and may preserve renal function... - Fetal endoscopic surgery: lessons learned and trends reviewedSteven F Fowler
Department of Surgery, Division of Pediatric Surgery and Fetal Treatment Center, University of California, San Francisco, CA, USA
J Pediatr Surg 37:1700-2. 2002.... - Subcutaneous endoscopically assisted ligation (SEAL) of the internal ring for repair of inguinal hernias in children: a novel techniqueMichael R Harrison
Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, CA 94143 0570, USA
J Pediatr Surg 40:1177-80. 2005..The safety, efficacy (recurrence risk), and cost-effectiveness of this unproven procedure must be tested against standard open repair in a trial... - Pre-emptive placement of a presealant for amniotic accessRaul A Cortes
Fetal Treatment Center, Department of Surgery, University of California, San Francisco, CA 94143-0570, USA
Am J Obstet Gynecol 193:1197-203. 2005..Further studies with different bioadhesives are needed, given the limitations of the glues that are described in this study... - Congenital diaphragmatic hernia associated with spinal anomaliesErich J Grethel
Fetal Treatment Center, Division of Pediatric Surgery, University of California, San Francisco, San Francisco, California 94143 0570, USA
Obstet Gynecol 109:485-8. 2007..We reviewed our series of patients with congenital diaphragmatic hernia and spinal anomalies to evaluate if their prognosis was altered... - Conflicts in wound classification of neonatal operationsLan T Vu
Department of Surgery, University of California, San Francisco, CA 94143 0570, USA
J Pediatr Surg 44:1206-11. 2009..This study sought to determine the reliability of wound classification guidelines when applied to neonatal operations... - Complicated monochorionic twin pregnancies: updates in fetal diagnosis and treatmentLarry Rand
Division of Perinatology and Genetics, Fetal Treatment Center, University of California, San Francisco, CA 94143, USA
Clin Perinatol 36:417-30, x-xi. 2009..The key to understanding complicated MC pregnancies lies in the placental angioarchitecture and intertwin vascular communications between the fetuses... - Spectrum of intrapartum management strategies for giant fetal cervical teratomaShinjiro Hirose
Department of Surgery, University of California, San Francisco, California 94143-0570, USA
J Pediatr Surg 38:446-50; discussion 446-50. 2003..In patients with airway obstruction, EXIT procedure provides the luxury of time to obtain airway control either by intubation, tracheostomy, or, if necessary, tumor resection on placental support... - Colonic atresia and choledochal cyst: a rare combinationAmar Nijagal
Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, 513 Parnassus Avenue, HSW 1601, San Francisco, CA 94143 0570, USA
Pediatr Surg Int 25:113-5. 2009..We report a case of choledochal cyst and colonic atresia in a term neonate. Our prenatal ultrasonographic and intraoperative findings support the idea that these two entities may be related... - In utero repair of myelomeningocele: experimental pathophysiology, initial clinical experience, and outcomesDiana L Farmer
Departments of Surgery and Neurosurgery and the Fetal Treatment Center, University of California, San Francisco, CA 94143 0570, USA
Arch Surg 138:872-8. 2003..Experimental work raises the possibility that in utero repair of myelomeningocele (MMC) may improve lower extremity, bladder, and bowel function, ameliorate the Arnold-Chiari malformation, and decrease the need for postnatal shunting... - Obstructing ileal duplication cyst infected with Salmonella in a 2-year-old boy: a case report and review of the literatureTim Jancelewicz
Department of Surgery, University of California, San Francisco, CA 94143 0104, USA
J Pediatr Surg 42:E19-21. 2007..We also present a review of the literature regarding these interesting lesions... - Indication for pediatric muscle biopsy determines usefulnessRamin Jamshidi
Department of Surgery, University of California, San Francisco, CA 94143 0570, USA
J Pediatr Surg 43:2199-201. 2008..Diagnostic skeletal muscle biopsy is an invasive procedure used for evaluation of neuromuscular disorders. We hypothesize that the yield of biopsy varies with its indication or suspected diagnosis... - Initial experience with complex laparoscopic biliary surgery in children: biliary atresia and choledochal cystHanmin Lee
Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, USA
J Pediatr Surg 39:804-7; discussion 804-7. 2004..Excellent visualization of the portal structures can be achieved laparoscopically with adequate retraction of the liver. Further follow-up is needed to determine broader application... - Congenital high airway obstruction sequence (CHAOS): a new case and a review of phenotypic featuresErica Sanford
Division of Medical Genetics, Department of Pediatrics, University of California, San Francisco, California 94143 0748, USA
Am J Med Genet A 158:3126-36. 2012..Our review provides valuable information on associated anomalies and survival in this complex sequence. The phenotypic variability seen in this review of patients makes it likely that the causes of CHAOS are genetically heterogeneous... - Extrapleural thoracoscopic repair of esophageal atresia with tracheoesophageal fistulaKuoJen Tsao
Fetal Treatment Center, University of California San Francisco, 513 Parnassus Avenue, HSW-1601, San Francisco, CA 94143, USA
Pediatr Surg Int 21:308-10. 2005..Many pediatric surgeons favor the extrapleural approach for two reasons: (1) containment of a potential leak within the extrapleural space, avoiding an empyema, and (2) easier transpleural access for future thoracic procedures... - The effect of fiber alignment and heparin coating on cell infiltration into nanofibrous PLLA scaffoldsKyle T Kurpinski
Joint Graduate Program in Bioengineering, University of California, Berkeley and University of California, San Francisco, USA Department of Bioengineering, University of California, Berkeley, USA
Biomaterials 31:3536-42. 2010..These results shed light on the importance of biophysical and biochemical properties of nanofibers in the regulation of cell infiltration into three-dimensional scaffolds and tissue remodeling... - Haploidentical donor T cells fail to facilitate engraftment but lessen the immune response of host T cells in murine fetal transplantationJeng-Chang Chen
Fetal Treatment Center, Department of Surgery, University of California, San Francisco, CA 94143-0793, USA
Br J Haematol 126:377-84. 2004..The persistence of donor cells in the peritoneal cavity also correlated with tolerance induction... - Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforationR Lawrence Moss
Section of Pediatric Surgery, Yale University School of Medicine, New Haven, Conn 06520 8062, USA
N Engl J Med 354:2225-34. 2006..We designed this multicenter randomized trial to compare outcomes of primary peritoneal drainage with laparotomy and bowel resection in preterm infants with perforated necrotizing enterocolitis... - A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndromeTimothy M Crombleholme
Fetal Care Center of Cincinnati, Division of Pediatric General, Thoracic, and Fetal Surgery, Cincinnati Children s Hospital, MLC 2023, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Am J Obstet Gynecol 197:396.e1-9. 2007..The objective of the study was to examine the effect of selective fetoscopic laser photocoagulation (SFLP) vs serial amnioreduction (AR) on perinatal mortality in severe twin-twin transfusion syndrome (TTTS)...