Ha Youn Lee

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression
    Ha Youn Lee
    Department of Biostatistics and Computational Biology, University of Rochester Medical Center, NY, USA
    PLoS Comput Biol 4:e1000240. 2008
  2. pmc Nef gene evolution from a single transmitted strain in acute SIV infection
    Benjamin N Bimber
    Department of Pathology and Laboratory Medicine, Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Retrovirology 6:57. 2009
  3. pmc Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models
    Ha Youn Lee
    Department of Biostatistics and Computational Biology, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA
    Bull Math Biol 71:1649-70. 2009
  4. pmc Accurate structure prediction of peptide-MHC complexes for identifying highly immunogenic antigens
    Min Sun Park
    Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, NY 14642, USA
    Mol Immunol 56:81-90. 2013
  5. pmc Designing a genome-based HIV incidence assay with high sensitivity and specificity
    Sung Yong Park
    Department of Biostatistics and Computational Biology, University of Rochester, New York 14642 0001, USA
    AIDS 25:F13-9. 2011
  6. pmc Simulation and prediction of the adaptive immune response to influenza A virus infection
    Ha Youn Lee
    Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York 14642, USA
    J Virol 83:7151-65. 2009

Research Grants

Collaborators

Detail Information

Publications6

  1. pmc Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression
    Ha Youn Lee
    Department of Biostatistics and Computational Biology, University of Rochester Medical Center, NY, USA
    PLoS Comput Biol 4:e1000240. 2008
    ....
  2. pmc Nef gene evolution from a single transmitted strain in acute SIV infection
    Benjamin N Bimber
    Department of Pathology and Laboratory Medicine, Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Retrovirology 6:57. 2009
    ....
  3. pmc Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models
    Ha Youn Lee
    Department of Biostatistics and Computational Biology, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA
    Bull Math Biol 71:1649-70. 2009
    ..The most profound effect of the presence of IL-4 was decreased death rates for smaller division classes, which supports a role of IL-4 in the protection of B cells from apoptosis...
  4. pmc Accurate structure prediction of peptide-MHC complexes for identifying highly immunogenic antigens
    Min Sun Park
    Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, NY 14642, USA
    Mol Immunol 56:81-90. 2013
    ..Our study offers the prospect of enhancing immunogenicity of vaccines by identifying MHC binding immunogens...
  5. pmc Designing a genome-based HIV incidence assay with high sensitivity and specificity
    Sung Yong Park
    Department of Biostatistics and Computational Biology, University of Rochester, New York 14642 0001, USA
    AIDS 25:F13-9. 2011
    ..Our study is to design a novel scheme of identifying incident infections in a highly accurate manner, based on the characteristics of HIV gene diversification within an infected individual...
  6. pmc Simulation and prediction of the adaptive immune response to influenza A virus infection
    Ha Youn Lee
    Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York 14642, USA
    J Virol 83:7151-65. 2009
    ..We further compared alternative model structures, for example, B-cell activation directly by the virus versus that through professional antigen-presenting cells or dendritic cell licensing of CD8 T cells...

Research Grants2

  1. Simulator for Primary HIV Replication and Evolution
    Ha Youn Lee; Fiscal Year: 2009
    ..This project will develop a computational simulation that can be used to model this critical phase of virus infection. The model is expected to have important utility in helping to design safe and effective HIV/AIDS vaccines. ..
  2. Simulator for Primary HIV Replication and Evolution
    Ha Youn Lee; Fiscal Year: 2010
    ..This project will develop a computational simulation that can be used to model this critical phase of virus infection. The model is expected to have important utility in helping to design safe and effective HIV/AIDS vaccines. ..