Grace A Lee

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Effects of ritonavir and amprenavir on insulin sensitivity in healthy volunteers
    Grace A Lee
    Department of Medicine, University of California, San Francisco, California, USA
    AIDS 21:2183-90. 2007
  2. doi request reprint The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers
    Vivian Y Pao
    Department of Medicine, University of California, CA, USA
    AIDS 24:265-70. 2010
  3. pmc Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers
    Steven A Taylor
    Department of Medicine, University of California, San Francisco, CA, USA
    J Acquir Immune Defic Syndr 55:361-4. 2010
  4. pmc Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers
    Grace A Lee
    Department of Medicine, University of California, San Francisco, California, USA
    Clin Infect Dis 43:658-60. 2006
  5. pmc The acute effects of HIV protease inhibitors on insulin suppression of glucose production in healthy HIV-negative men
    Grace A Lee
    Department of Medicine, University of California, San Francisco, CA, USA
    J Acquir Immune Defic Syndr 52:246-8. 2009
  6. ncbi request reprint Indinavir increases glucose production in healthy HIV-negative men
    Jean Marc Schwarz
    Department of Medicine, University of California, San Francisco, CA, USA
    AIDS 18:1852-4. 2004
  7. pmc The metabolic effects of lopinavir/ritonavir in HIV-negative men
    Grace A Lee
    Metabolism Section 111F, San Francisco Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    AIDS 18:641-9. 2004
  8. pmc The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia
    Kathleen Mulligan
    Department of Medicine, University of California, San Francisco, USA
    J Clin Endocrinol Metab 94:1137-44. 2009
  9. pmc The effects of low-dose growth hormone in HIV-infected men with fat accumulation: a pilot study
    Joan C Lo
    Div of Endocrinology, General Clinical Research Center at San Francisco General Hospital, San Francisco, California 94110, USA
    Clin Infect Dis 39:732-5. 2004
  10. pmc HIV therapy, metabolic syndrome, and cardiovascular risk
    Vivian Pao
    Department of Veterans Affairs Medical Center, Metabolism Section Box 111F, 4150 Clement Street, San Francisco, CA 94121, USA
    Curr Atheroscler Rep 10:61-70. 2008

Detail Information

Publications13

  1. pmc Effects of ritonavir and amprenavir on insulin sensitivity in healthy volunteers
    Grace A Lee
    Department of Medicine, University of California, San Francisco, California, USA
    AIDS 21:2183-90. 2007
    ..Some HIV protease inhibitors (PIs) have been shown to induce insulin resistance in vitro but the degree to which specific PIs affect insulin sensitivity in humans is less well understood...
  2. doi request reprint The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers
    Vivian Y Pao
    Department of Medicine, University of California, CA, USA
    AIDS 24:265-70. 2010
    ..We studied the effects of the protease inhibitor combination lopinavir and ritonavir on insulin secretion, insulin sensitivity, and lipid metabolism in HIV-negative persons...
  3. pmc Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers
    Steven A Taylor
    Department of Medicine, University of California, San Francisco, CA, USA
    J Acquir Immune Defic Syndr 55:361-4. 2010
    ..Boosting dose ritonavir (100-200 mg) is the most commonly prescribed PI, yet its effects on glucose metabolism have not been described in the absence of another PI...
  4. pmc Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers
    Grace A Lee
    Department of Medicine, University of California, San Francisco, California, USA
    Clin Infect Dis 43:658-60. 2006
    ..Insulin resistance from protease inhibitors may decrease with prolonged use; an increase in adiponectin levels may mediate this effect...
  5. pmc The acute effects of HIV protease inhibitors on insulin suppression of glucose production in healthy HIV-negative men
    Grace A Lee
    Department of Medicine, University of California, San Francisco, CA, USA
    J Acquir Immune Defic Syndr 52:246-8. 2009
    ..The effects of different HIV protease inhibitors (PIs) on peripheral insulin resistance have been described, but less is known about their effects on insulin suppression of endogenous glucose production (EGP)...
  6. ncbi request reprint Indinavir increases glucose production in healthy HIV-negative men
    Jean Marc Schwarz
    Department of Medicine, University of California, San Francisco, CA, USA
    AIDS 18:1852-4. 2004
    ..During the euglycemic hyperinsulinemic clamp, indinavir blunted the ability of insulin to suppress glucose production. Therefore, indinavir worsens hepatic insulin sensitivity, increasing endogenous glucose production...
  7. pmc The metabolic effects of lopinavir/ritonavir in HIV-negative men
    Grace A Lee
    Metabolism Section 111F, San Francisco Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    AIDS 18:641-9. 2004
    ..Therefore, we tested the effects of the PI combination lopinavir and ritonavir on glucose and lipid metabolism in HIV-negative subjects...
  8. pmc The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia
    Kathleen Mulligan
    Department of Medicine, University of California, San Francisco, USA
    J Clin Endocrinol Metab 94:1137-44. 2009
    ..Leptin deficiency is associated with dyslipidemia and insulin resistance in animals and humans with lipoatrophy; leptin replacement ameliorates these abnormalities...
  9. pmc The effects of low-dose growth hormone in HIV-infected men with fat accumulation: a pilot study
    Joan C Lo
    Div of Endocrinology, General Clinical Research Center at San Francisco General Hospital, San Francisco, California 94110, USA
    Clin Infect Dis 39:732-5. 2004
    ..Visceral adipose tissue (VAT) levels did not change significantly for the group as a whole, although a reduction in the VAT level was seen in patients with a greater VAT level at baseline...
  10. pmc HIV therapy, metabolic syndrome, and cardiovascular risk
    Vivian Pao
    Department of Veterans Affairs Medical Center, Metabolism Section Box 111F, 4150 Clement Street, San Francisco, CA 94121, USA
    Curr Atheroscler Rep 10:61-70. 2008
    ..It remains to be determined whether CVD rates in HIV infection are higher than might be predicted from traditional risk factors, including smoking...
  11. ncbi request reprint The effects of HIV protease inhibitors on carbohydrate and lipid metabolism
    Grace A Lee
    Department of Veterans Affairs Medical Center, Metabolism Section Box 111F, 4150 Clement Street, San Francisco, CA 94121, USA
    Curr HIV/AIDS Rep 2:39-50. 2005
    ..This review examines the direct effects of PIs on glucose and lipid metabolism by assessing prospective studies of HIV-infected and healthy normal volunteers, and in vitro studies...
  12. ncbi request reprint Development of multiple lipomas during treatment with rosiglitazone in a patient with HIV-associated lipoatrophy
    Derek D Mafong
    AIDS 18:1742-4. 2004
  13. ncbi request reprint HIV protease inhibitors increase adiponectin levels in HIV-negative men
    Grace A Lee
    J Acquir Immune Defic Syndr 36:645-7. 2004