Dong Won Lee

Summary

Affiliation: University of South Florida
Country: USA

Publications

  1. pmc Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline
    Dong Won Lee
    Division of Allergy and Immunology and Joy McCann Culverhouse Airway Disease Center, Department of Internal Medicine, University of South Florida College of Medicine and James A, Haley Veteran s Hospital, Tampa, FL 33612, USA
    Respir Res 7:112. 2006
  2. ncbi request reprint Detoxification of amitriptyline by oligochitosan derivatives
    Dong Won Lee
    Department of Materials Science and Engineering, University of Florida, Gainesville, FL 32611, USA
    Biotechnol Lett 26:713-6. 2004
  3. ncbi request reprint Oligochitosan derivatives bearing electron-deficient aromatic rings for adsorption of amitriptyline: implications for drug detoxification
    Dong Won Lee
    Department of Materials Science and Engineering, University of Florida, Gainesville, Florida 32611, USA
    Biomacromolecules 5:1310-5. 2004
  4. ncbi request reprint Aromatic-aromatic interaction of amitriptyline: implication of overdosed drug detoxification
    Dong Won Lee
    Department of Materials Science and Engineering, Gainesville, Florida 32611, USA
    J Pharm Sci 94:373-81. 2005

Collaborators

Detail Information

Publications4

  1. pmc Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline
    Dong Won Lee
    Division of Allergy and Immunology and Joy McCann Culverhouse Airway Disease Center, Department of Internal Medicine, University of South Florida College of Medicine and James A, Haley Veteran s Hospital, Tampa, FL 33612, USA
    Respir Res 7:112. 2006
    ..It was hypothesized that adsorption of theophylline to chitosan nanoparticles modified by the addition of thiol groups would improve theophylline absorption by the bronchial epithelium and enhance its anti-inflammatory effects...
  2. ncbi request reprint Detoxification of amitriptyline by oligochitosan derivatives
    Dong Won Lee
    Department of Materials Science and Engineering, University of Florida, Gainesville, FL 32611, USA
    Biotechnol Lett 26:713-6. 2004
    ..Drug uptake test by HPLC reveals that dinitrophenyl chitosan particles (1-2 microm) at 0.4 wt% (w/v) in a saline solution (pH 6.9) adsorb 90% amitriptyline within 30 min...
  3. ncbi request reprint Oligochitosan derivatives bearing electron-deficient aromatic rings for adsorption of amitriptyline: implications for drug detoxification
    Dong Won Lee
    Department of Materials Science and Engineering, University of Florida, Gainesville, Florida 32611, USA
    Biomacromolecules 5:1310-5. 2004
    ..Dinitrobenzenesulfonyl rings show a larger variation in chemical shift due to the presence of the electron deficient nitro groups...
  4. ncbi request reprint Aromatic-aromatic interaction of amitriptyline: implication of overdosed drug detoxification
    Dong Won Lee
    Department of Materials Science and Engineering, Gainesville, Florida 32611, USA
    J Pharm Sci 94:373-81. 2005
    ..Isolated rat heart tests revealed that dinitrobenzenesulfonyl oligochitosan prevented the amitriptyline-induced cardiotoxicity and was itself not cardiotoxic...