Chi H Lee

Summary

Affiliation: University of Missouri-Kansas City
Country: USA

Publications

  1. ncbi Effects of chelating agents on the rheological property of cervical mucus
    Chi H Lee
    College of Pharmacy, The University of Missouri, Kansas City, MO, USA
    Contraception 65:435-40. 2002
  2. ncbi Characterization of a female controlled drug delivery system for microbicides
    Yicheng Wang
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, 64110, USA
    Contraception 66:281-7. 2002
  3. doi Thixotropic property in pharmaceutical formulations
    Chi H Lee
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City, MO 64110, USA
    J Control Release 136:88-98. 2009
  4. pmc Computational analysis and predictive modeling of polymorph descriptors
    Yugyung Lee
    Division of Pharmaceutical Sciences, College of Pharmacy, University of Missouri Kansas City, Missouri, MO 64108, USA
    Chem Cent J 7:23. 2013
  5. doi Characterization of nitric oxide delivery systems produced by various nanotechnologies
    Chi H Lee
    School of Pharmacy, University of Missouri, Kansas City, MO, USA
    Methods Mol Biol 704:169-85. 2011
  6. doi Physiological variables involved in heart valve substitute calcification
    Chi H Lee
    University of Missouri Kansas City, School of Pharmacy, Department of Pharmaceutical Sciences, Kansas City, MO 64110, USA
    Expert Opin Biol Ther 9:1031-42. 2009
  7. ncbi Biomedical applications of collagen
    C H Lee
    Department of Pharmaceutics, College of Pharmacy, The University of Missouri Kansas City, 5005 Rockhill Rd, Katz Bdg 108, Kansas City, MO 64110, USA
    Int J Pharm 221:1-22. 2001
  8. pmc Effect of gramicidin on percutaneous permeation of a model drug
    C H Lee
    University of Missouri Kansas City, MO 64110, USA
    AAPS PharmSciTech 1:E13. 2000
  9. doi Characterization of nitric oxide-releasing microparticles for the mucosal delivery
    Jin Wook Yoo
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City, Missouri 64110, USA
    J Biomed Mater Res A 92:1233-43. 2010
  10. ncbi Inhibition of CEM calcification by the sequential pretreatment with ethanol and EDTA
    Anuj Singla
    College of Pharmacy, The University of Missouri, 5005 Rockhill Road, Kansas City, Missouri 64110, USA
    J Biomed Mater Res A 64:706-13. 2003

Collaborators

  • Yugyung Lee
  • Eun Sang Choe
  • Yi Liu
  • Richard A Hopkins
  • H K Choi
  • Sang Chul Shin
  • Jin Wook Yoo
  • Gayathri Acharya
  • Sravanthi Cheeti
  • Kiran Dharmala
  • Yicheng Wang
  • Anuj Singla
  • Rajeshree Singla
  • Wuchen Wang
  • Bharat Warrier
  • Bharat K Warrier
  • Hyewon Youn
  • Eun Sang Choe
  • Namita Giri
  • Jae Suk Lee
  • Sung Min Ahn
  • Keejong Hong
  • Rama Mallipeddi
  • Pradeep Kumar Karla
  • Elisabet Kostoryz
  • Joo Cheol Park
  • Jang Soo Chun

Detail Information

Publications31

  1. ncbi Effects of chelating agents on the rheological property of cervical mucus
    Chi H Lee
    College of Pharmacy, The University of Missouri, Kansas City, MO, USA
    Contraception 65:435-40. 2002
    ..This result indicates that spermicidal activity exerted by high concentrations of EDTA is in part due to its effect on the rheological properties of cervical mucus or semen...
  2. ncbi Characterization of a female controlled drug delivery system for microbicides
    Yicheng Wang
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, 64110, USA
    Contraception 66:281-7. 2002
    ..Mucin played an important role in the regulation of viscosity and surface tension of VFS. DSC study demonstrated that carbopol gel showed good biocompatibility and did not cause any conformational changes in rat vaginal membrane...
  3. doi Thixotropic property in pharmaceutical formulations
    Chi H Lee
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City, MO 64110, USA
    J Control Release 136:88-98. 2009
    ..The comprehensive analysis of rheological and mechanical properties will provide an insight into the potential usage of thixotropic formulations as drug delivery systems...
  4. pmc Computational analysis and predictive modeling of polymorph descriptors
    Yugyung Lee
    Division of Pharmaceutical Sciences, College of Pharmacy, University of Missouri Kansas City, Missouri, MO 64108, USA
    Chem Cent J 7:23. 2013
    ....
  5. doi Characterization of nitric oxide delivery systems produced by various nanotechnologies
    Chi H Lee
    School of Pharmacy, University of Missouri, Kansas City, MO, USA
    Methods Mol Biol 704:169-85. 2011
    ..The pharmacological assessments of advanced formulations using in vitro and in vivo tests are also described in detail. These systems can be used for the treatment of cardiovascular diseases and sexual dysfunctions...
  6. doi Physiological variables involved in heart valve substitute calcification
    Chi H Lee
    University of Missouri Kansas City, School of Pharmacy, Department of Pharmaceutical Sciences, Kansas City, MO 64110, USA
    Expert Opin Biol Ther 9:1031-42. 2009
    ..This review examines our understanding of the systemic cellular behavior and physiological regulation processes behind BHV calcification and its clinical applications...
  7. ncbi Biomedical applications of collagen
    C H Lee
    Department of Pharmaceutics, College of Pharmacy, The University of Missouri Kansas City, 5005 Rockhill Rd, Katz Bdg 108, Kansas City, MO 64110, USA
    Int J Pharm 221:1-22. 2001
    ..The advantages and disadvantages of each system are also discussed...
  8. pmc Effect of gramicidin on percutaneous permeation of a model drug
    C H Lee
    University of Missouri Kansas City, MO 64110, USA
    AAPS PharmSciTech 1:E13. 2000
    ..The enhancing effect of gramicidin on percutaneous absorption of a model drug is mainly attributed to increasing the diffusivity in the hydration domain of the skin and rearranging the lipid bilayer in the stratum corneum...
  9. doi Characterization of nitric oxide-releasing microparticles for the mucosal delivery
    Jin Wook Yoo
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City, Missouri 64110, USA
    J Biomed Mater Res A 92:1233-43. 2010
    ..These findings suggest that NO-releasing microparticles could improve the vaginal blood perfusion and open up the possibilities of novel treatment of FSAD...
  10. ncbi Inhibition of CEM calcification by the sequential pretreatment with ethanol and EDTA
    Anuj Singla
    College of Pharmacy, The University of Missouri, 5005 Rockhill Road, Kansas City, Missouri 64110, USA
    J Biomed Mater Res A 64:706-13. 2003
    ..The sequential inhibitory effects of ethanol and EDTA could occur due to the distinct separate actions of each agent, thereby achieving a relatively greater inhibition of calcification...
  11. doi Advanced polymeric matrix for valvular complications
    Gayathri Acharya
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, Kansas City, Missouri 64108, USA
    J Biomed Mater Res A 100:1151-9. 2012
    ..PLLA matrix system loaded with NPs containing NO donors could provide a new platform for sustained and controlled delivery of NO, significantly reducing valvular complications...
  12. doi pH-sensitive Eudragit nanoparticles for mucosal drug delivery
    Jin Wook Yoo
    Division of Pharmaceutical Sciences, University of Missouri, Kansas City, MO 64110, USA
    Int J Pharm 403:262-7. 2011
    ..The pH-sensitive nanoparticles would be a promising carrier for the vaginal-specific delivery of various therapeutic drugs including microbicides and peptides/proteins...
  13. doi Pharmacological activity and protein phosphorylation caused by nitric oxide-releasing microparticles
    Jin Wook Yoo
    Division of Pharmaceutical Sciences, University of Missouri Kansas City, Kansas City, MO 64110, USA
    Biomaterials 31:552-8. 2010
    ..The results of this work supported that NO-releasing microparticles could improve the vaginal blood flow without causing cytotoxic effects and PKC-MAP kinase modules are involved in the NO-induced blood flow regulation process...
  14. pmc The involvement of intracellular calcium in the MCT-mediated uptake of lactic acid by HeLa cells
    Sravanthi Cheeti
    Division of Pharmaceutical Sciences, The University of Missouri School of Pharmacy, Kansas City, Missouri 64110 2499, USA
    Mol Pharm 7:169-76. 2010
    ..An understanding of the role of [Ca2+](in) in the MCT mediated transport process could provide an efficient strategy to improve the systemic delivery of monocarboxylate substrates through the cervical mucosa...
  15. ncbi Assessment of diffusion coefficient from mucoadhesive barrier devices using artificial neural networks
    Yugyung Lee
    School of Computing and Engineering, School of Pharmacy, The University of Missouri, Kansas City, MO 64110, United States
    Int J Pharm 351:119-26. 2008
    ....
  16. ncbi The physicodynamic properties of mucoadhesive polymeric films developed as female controlled drug delivery system
    Jin Wook Yoo
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City, MO 64110, USA
    Int J Pharm 309:139-45. 2006
    ..5:1.5:1 and 1:2:1 seem to be optimal compositions for FcDDS, as they showed good peelability, relatively high swelling index and moderate tensile strength, and achieved the target release rate of SDS for 6h...
  17. ncbi Effects of intrinsic variables on release of sodium dodecyl sulfate from a female controlled drug delivery system
    Yicheng Wang
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, 5005 Rockhill Road, Kansas City, MO 64110, USA
    Int J Pharm 282:173-81. 2004
    ..It can be concluded that FcDDS can be exploited as a controlled delivery device for prevention against sexually transmitted diseases...
  18. doi Development of chitosan-SLN microparticles for chemotherapy: in vitro approach through efflux-transporter modulation
    Kiran Dharmala
    Division of Pharmaceutical Sciences, College of Pharmacy, University of Missouri Kansas City, MO 64110, United States
    J Control Release 131:190-7. 2008
    ..Judging from these results, CSM can be an efficient drug delivery system for the substrates susceptible to the efflux-transporters...
  19. ncbi ICAM-1 expression in vaginal cells as a potential biomarker for inflammatory response
    Hyewon Youn
    Department of Urology, University of Kansas Medical Center, Kansas City, KS, USA
    Biomarkers 13:257-69. 2008
    ....
  20. doi In vivo evaluation of vaginal films for mucosal delivery of nitric oxide
    Jin Wook Yoo
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri at Kansas City, 5005 Rockhill Rd, MO 64110, USA
    Biomaterials 30:3978-85. 2009
    ..The NO-releasing vaginal films might be used as a promising treatment device against FSAD...
  21. doi Effects of dialdehyde starch on calcification of collagen matrix
    Yi Liu
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri at Kansas City, Kansas City, Missouri 64110, USA
    J Biomed Mater Res A 99:485-92. 2011
    ..Further optimization process is needed for the suitable crosslinking conditions of DAS, which subsequently enhances thermal strength and anticalcification activities of COL matrix...
  22. ncbi Biocompatibility of components of a female controlled drug delivery system
    Bharat K Warrier
    Department of Pharmaceutics, Division of Pharmaceutical Sciences, University of Missouri School of Pharmacy, 5005 Rockhill Road, Katz Building 108, Kansas City, MO 64110 2499, USA
    J Biomed Mater Res A 71:209-16. 2004
    ..This work has demonstrated that FcDDS containing EDTA is biocompatible and safe to be used as an intravaginal barrier device...
  23. pmc Optimization of cardiovascular stent against restenosis: factorial design-based statistical analysis of polymer coating conditions
    Gayathri Acharya
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, Kansas City, Missouri, United States of America
    PLoS ONE 7:e43100. 2012
    ..The results of this study demonstrated that PCL matrix containing GSNO is a promising system for stent surface coating against restenosis...
  24. ncbi The functional role of C-reactive protein in aortic wall calcification
    Bharat Warrier
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, Kansas City, MO 64110, USA
    Cardiology 104:57-64. 2005
    ..The results of this work clearly revealed that CRP has indirect vascular effects, leading to an increased rate of aortic wall calcification...
  25. ncbi The role of monocarboxylate transporters in uptake of lactic acid in HeLa cells
    Sravanthi Cheeti
    Division of Pharmaceutical Sciences, University of Missouri, School of Pharmacy, 5005 Rock Hill Road, Kansas City, MO 64110 2499, USA
    Int J Pharm 325:48-54. 2006
    ..MCT isoforms 1, 5 and 6 in HeLa cells were identified by RT-PCR. HeLa cell line can be used as an effective screening tool for intravaginally administered drugs targeted toward MCT...
  26. ncbi Effects of calcium modulation on percutaneous absorption of a model drug
    Rajeshree Singla
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City 64110, USA
    Pharm Res 19:1381-6. 2002
    ..To investigate the effect of modulation of the calcium gradient in the skin on the percutaneous absorption of nicotinic acid (NA)...
  27. ncbi Effects of glycerol on the in vitro percutaneous absorption of all-trans retinoic acid
    Rajeshree Singla
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, Missouri 64110, USA
    Pharm Dev Technol 8:229-37. 2003
    ..48 +/- 0.14 vs. 2.45 +/- 0.21). An addition of glycerol, an osmotherapeutic agent, in the physiological receptor solution seemed to enhance the percutaneous absorption of RA by affecting the partition coefficient of RA...
  28. doi Review: the physiological and computational approaches for atherosclerosis treatment
    Wuchen Wang
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City, MO 64108, USA
    Int J Cardiol 167:1664-76. 2013
    ..The physiological and computational approaches, such as percutaneous coronary intervention and stent design modeling, to detect, evaluate and mitigate this malicious progression were also discussed. ..
  29. ncbi Drug delivery systems for hormone therapy
    Jin Wook Yoo
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City, MO 64110, USA
    J Control Release 112:1-14. 2006
    ..The extensive reviews and comparisons on the characteristics of various types of HT could lead to the development of an efficient delivery formulation which maximizes patient compliance and minimizes adverse effects for individual users...
  30. ncbi Effect of elastin on the calcification rate of collagen-elastin matrix systems
    Anuj Singla
    College of Pharmacy, The University of Missouri Kansas City, Missouri 64110, USA
    J Biomed Mater Res 60:368-74. 2002
    ..27 mmol/cm(2)/h). These results indicate that elastin has a significant role in tissue calcification and that elastin's resistance to ethanol penetration partially contributes less effectiveness of ethanol on aortic wall calcification...
  31. ncbi EDTA-induced activation of Ca-regulated proteins in the vaginal mucosa
    Eun Sang Choe
    Department of Biology, Pusan National University, Pusan 609 735, Korea
    J Biomed Mater Res A 68:159-67. 2004
    ..The specific tissue responses exerted by the loading components of a biomaterial-based system should be fully taken into consideration for its intravaginal application...