L Lecourtier

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Habenula lesions cause impaired cognitive performance in rats: implications for schizophrenia
    Lucas Lecourtier
    NS Research, WSJ 386 262, Novartis Institutes for BioMedical Research, CH 4002 Basel, Switzerland
    Eur J Neurosci 19:2551-60. 2004
  2. ncbi request reprint Impaired cognitive performance in rats after complete epithalamus lesions, but not after pinealectomy alone
    Lucas Lecourtier
    NS Research, WSJ 386 262, Novartis Institutes for BioMedical Research, CH 4002 Basel, Switzerland CNRS UMR 5106, Laboratoire de Neurosciences Cognitives, Universite de Bordeaux 1, Avenue des Facultes, 33405 Cedex Talence, France
    Behav Brain Res 161:276-85. 2005
  3. ncbi request reprint A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition
    Lucas Lecourtier
    Department of Neuroscience, University of Pittsburgh, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Neurosci Biobehav Rev 31:658-72. 2007
  4. ncbi request reprint Habenula lesions alter synaptic plasticity within the fimbria-accumbens pathway in the rat
    L Lecourtier
    NS Research, Novartis Institutes for BioMedical Research, Basel, Switzerland
    Neuroscience 141:1025-32. 2006
  5. pmc Differential tonic influence of lateral habenula on prefrontal cortex and nucleus accumbens dopamine release
    Lucas Lecourtier
    Center for Neuroscience, A210 Langley Hall, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Eur J Neurosci 27:1755-62. 2008
  6. ncbi request reprint Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice
    Martin Gassmann
    Pharmazentrum, Department of Clinical Biological Sciences, University of Basel, CH 4056 Basel, Switzerland
    J Neurosci 24:6086-97. 2004
  7. ncbi request reprint Bilateral lesions of the habenula induce attentional disturbances in rats
    Lucas Lecourtier
    Psychiatry Program, Neuroscience Research, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland
    Neuropsychopharmacology 30:484-96. 2005
  8. pmc Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex
    Lucas Lecourtier
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Biol Psychiatry 62:739-46. 2007

Collaborators

  • J M Fritschy
  • R Garcia
  • Bita Moghaddam
  • Yann Humeau
  • Martin Gassmann
  • Johannes Mosbacher
  • Herman van der Putten
  • Andreas L├╝thi
  • Klaus Klebs
  • Corinne Haller
  • Valerie Schuler
  • Clive Gentry
  • Bernd Kinzel
  • Samuel Barbieri
  • Gilles Sansig
  • Peter H Kelly
  • Matthias Muller
  • Hamdy Shaban
  • Rejan Vigot
  • Markus Schmutz
  • Bernhard Bettler
  • Klemens Kaupmann
  • Cedric Mombereau
  • Anne Lise Jaton
  • Jakob Heid
  • Wolfgang Froestl
  • John F Cryan

Detail Information

Publications8

  1. ncbi request reprint Habenula lesions cause impaired cognitive performance in rats: implications for schizophrenia
    Lucas Lecourtier
    NS Research, WSJ 386 262, Novartis Institutes for BioMedical Research, CH 4002 Basel, Switzerland
    Eur J Neurosci 19:2551-60. 2004
    ..The results are consistent with a role of the habenula in cognition, and with the view that pathology of the habenula may contribute to the cognitive impairments of schizophrenia...
  2. ncbi request reprint Impaired cognitive performance in rats after complete epithalamus lesions, but not after pinealectomy alone
    Lucas Lecourtier
    NS Research, WSJ 386 262, Novartis Institutes for BioMedical Research, CH 4002 Basel, Switzerland CNRS UMR 5106, Laboratoire de Neurosciences Cognitives, Universite de Bordeaux 1, Avenue des Facultes, 33405 Cedex Talence, France
    Behav Brain Res 161:276-85. 2005
    ..Thus, loss of pineal function causes no deficits in these behaviours and does not alter the qualitative pattern of deficits resulting from habenula damage...
  3. ncbi request reprint A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition
    Lucas Lecourtier
    Department of Neuroscience, University of Pittsburgh, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Neurosci Biobehav Rev 31:658-72. 2007
    ..Electrophysiological studies indicate a role in metaplasticity, the modulation of neuroplasticity. These studies thus reveal important roles of the habenular complex in learning, memory and attention...
  4. ncbi request reprint Habenula lesions alter synaptic plasticity within the fimbria-accumbens pathway in the rat
    L Lecourtier
    NS Research, Novartis Institutes for BioMedical Research, Basel, Switzerland
    Neuroscience 141:1025-32. 2006
    ..Finally, this study suggests that dysfunction of the habenula could contribute to cognitive alterations in diseases such as schizophrenia, where the habenula is reported to exhibit exaggerated calcification...
  5. pmc Differential tonic influence of lateral habenula on prefrontal cortex and nucleus accumbens dopamine release
    Lucas Lecourtier
    Center for Neuroscience, A210 Langley Hall, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Eur J Neurosci 27:1755-62. 2008
    ....
  6. ncbi request reprint Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice
    Martin Gassmann
    Pharmazentrum, Department of Clinical Biological Sciences, University of Basel, CH 4056 Basel, Switzerland
    J Neurosci 24:6086-97. 2004
    ..It is therefore possible that functional GABAB receptors exist in neurons that naturally lack GABAB(2) subunits...
  7. ncbi request reprint Bilateral lesions of the habenula induce attentional disturbances in rats
    Lucas Lecourtier
    Psychiatry Program, Neuroscience Research, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland
    Neuropsychopharmacology 30:484-96. 2005
    ..Implications of these findings for the hypothesis that habenula dysfunction is involved in cognitive symptoms of schizophrenia are discussed...
  8. pmc Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex
    Lucas Lecourtier
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Biol Psychiatry 62:739-46. 2007
    ....