Karl Ferdinand Lechtreck

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi Analysis of Chlamydomonas SF-assemblin by GFP tagging and expression of antisense constructs
    Karl Ferdinand Lechtreck
    Botanisches Institut, Universitat zu Koln, Germany
    J Cell Sci 115:1511-22. 2002
  2. ncbi Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility
    Karl Ferdinand Lechtreck
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Biol 176:473-82. 2007
  3. ncbi The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella
    Karl Ferdinand Lechtreck
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, 01655, USA
    J Cell Biol 187:1117-32. 2009
  4. ncbi HA-tagging of putative flagellar proteins in Chlamydomonas reinhardtii identifies a novel protein of intraflagellar transport complex B
    Karl Ferdinand Lechtreck
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Cell Motil Cytoskeleton 66:469-82. 2009
  5. ncbi Mutations in Hydin impair ciliary motility in mice
    Karl Ferdinand Lechtreck
    Department of Cell, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Biol 180:633-43. 2008
  6. ncbi CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content
    Branch Craige
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Biol 190:927-40. 2010
  7. ncbi High-speed digital imaging of ependymal cilia in the murine brain
    Karl Ferdinand Lechtreck
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Methods Cell Biol 91:255-64. 2009
  8. ncbi GFP as a tool for the analysis of proteins in the flagellar basal apparatus of Chlamydomonas
    Jutta Schoppmeier
    Department of Botany, University of Cologne, Cologne, Germany
    Cell Motil Cytoskeleton 61:189-200. 2005
  9. ncbi Striated fiber assemblin in apicomplexan parasites
    Karl-Ferdinand Lechtreck
    Botanists Institut, , Gyrhofstr 15, D-50931 Cologne, Germany
    Mol Biochem Parasitol 128:95-9. 2003
  10. ncbi The NIT1 promoter allows inducible and reversible silencing of centrin in Chlamydomonas reinhardtii
    Bettina Koblenz
    Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Ave. North, Worcester, MA 01655, USA
    Eukaryot Cell 4:1959-62. 2005

Collaborators

Detail Information

Publications11

  1. ncbi Analysis of Chlamydomonas SF-assemblin by GFP tagging and expression of antisense constructs
    Karl Ferdinand Lechtreck
    Botanisches Institut, Universitat zu Koln, Germany
    J Cell Sci 115:1511-22. 2002
    ..In these strains we observed defects in flagellar assembly, indicating an important role for noncontractile striated roots in the flagella apparatus...
  2. ncbi Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility
    Karl Ferdinand Lechtreck
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Biol 176:473-82. 2007
    ..Hydrocephalus caused by mutations in hydin likely involves the malfunctioning of cilia because of a defect in the CP...
  3. ncbi The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella
    Karl Ferdinand Lechtreck
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, 01655, USA
    J Cell Biol 187:1117-32. 2009
    ..We conclude that the BBSome is carried by IFT but is an adapter rather than an integral component of the IFT machinery. C. reinhardtii BBS4 may be required for the export of signaling proteins from the flagellum via IFT...
  4. ncbi HA-tagging of putative flagellar proteins in Chlamydomonas reinhardtii identifies a novel protein of intraflagellar transport complex B
    Karl Ferdinand Lechtreck
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Cell Motil Cytoskeleton 66:469-82. 2009
    ..Cell Motil. Cytoskeleton 2009. (c) 2009 Wiley-Liss, Inc...
  5. ncbi Mutations in Hydin impair ciliary motility in mice
    Karl Ferdinand Lechtreck
    Department of Cell, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Biol 180:633-43. 2008
    ..Similar defects are observed for cilia in trachea. We conclude that hydrocephalus in hydin mutants is caused by a central pair defect impairing ciliary motility and fluid transport in the brain...
  6. ncbi CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content
    Branch Craige
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Cell Biol 190:927-40. 2010
    ..The results indicate that CEP290 is required to form microtubule-membrane linkers that tether the flagellar membrane to the transition zone microtubules, and is essential for controlling flagellar protein composition...
  7. ncbi High-speed digital imaging of ependymal cilia in the murine brain
    Karl Ferdinand Lechtreck
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Methods Cell Biol 91:255-64. 2009
    ..The technique is useful for detailed assessment of how various conditions or mutations affect the fidelity of ciliary motility at the ependyma. The methods are also applicable to other ciliated epithelia, for example, in airways...
  8. ncbi GFP as a tool for the analysis of proteins in the flagellar basal apparatus of Chlamydomonas
    Jutta Schoppmeier
    Department of Botany, University of Cologne, Cologne, Germany
    Cell Motil Cytoskeleton 61:189-200. 2005
    ..In conclusion, in Chlamydomonas GFP-tagging is a useful tool for yielding new insights into the function and properties of the analyzed proteins...
  9. ncbi Striated fiber assemblin in apicomplexan parasites
    Karl-Ferdinand Lechtreck
    Botanists Institut, , Gyrhofstr 15, D-50931 Cologne, Germany
    Mol Biochem Parasitol 128:95-9. 2003
  10. ncbi The NIT1 promoter allows inducible and reversible silencing of centrin in Chlamydomonas reinhardtii
    Bettina Koblenz
    Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Ave. North, Worcester, MA 01655, USA
    Eukaryot Cell 4:1959-62. 2005
    ..The effect was reversible, demonstrating that the NIT1 promoter allowed controlled RNA interference in Chlamydomonas reinhardtii...
  11. ncbi Centrin deficiency in Chlamydomonas causes defects in basal body replication, segregation and maturation
    Bettina Koblenz
    Department of Botany, University of Cologne, Gyrhofstr. 15, D-50931 Cologne, Germany
    J Cell Sci 116:2635-46. 2003
    ..We propose that basal body segregation in Chlamydomonas depends on an extranuclear array of microtubules independent of the mitotic spindle...