Philip E LeBoit

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint What do these cells prove?
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, USA
    Am J Dermatopathol 25:355-6. 2003
  2. ncbi request reprint What genomics has taught me about melanocytic neoplasms
    P E LeBoit
    Department of Pathology and Dermatology, University of California, San Francisco, CA, USA
    G Ital Dermatol Venereol 147:239-49. 2012
  3. doi request reprint What sentinel node biopsy in patients with melanoma (or patients whose doctors worry that they could have melanoma) might and might not do
    Philip E LeBoit
    Department of Pathology, University of California at San Francisco School of Medicine, 1701 Divisadero Street, Suite 350, San Francisco, CA 94115, USA
    Clin Dermatol 27:588-93. 2009
  4. pmc Use of fluorescence in situ hybridization (FISH) to distinguish intranodal nevus from metastatic melanoma
    Scott R Dalton
    Department of Pathology, Wilford Hall Medical Center, Lackland AFB, TX, USA
    Am J Surg Pathol 34:231-7. 2010
  5. pmc Distribution and significance of occult intraepidermal tumor cells surrounding primary melanoma
    Jeffrey P North
    UCSF School of Medicine, University of California, San Francisco, California, USA
    J Invest Dermatol 128:2024-30. 2008
  6. ncbi request reprint Seborrheic keratosis with basal clear cells: a distinctive microscopic mimic of melanoma in situ
    Isaac M Neuhaus
    Department of Dermatology, University of California, San Francisco, California, USA
    J Am Acad Dermatol 54:132-5. 2006
  7. ncbi request reprint Fluorescence in situ hybridization as an ancillary tool in the diagnosis of ambiguous melanocytic neoplasms: a review of 804 cases
    Jeffrey P North
    Departments of Pathology Dermatology The Helen Diller Comprehensive Cancer Center, University of California, San Francisco, CA
    Am J Surg Pathol 38:824-31. 2014
  8. pmc Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomas
    Boris C Bastian
    Department of Dermatology and Pathology, University of California at San Francisco Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 0808, USA
    Am J Pathol 161:1163-9. 2002
  9. ncbi request reprint Persistent nevus, with "no" previous biopsy
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, USA
    Am J Dermatopathol 26:347-8. 2004
  10. ncbi request reprint Ducking stray "magic bullets": a Melan-A alert
    John C Maize
    Department of Dermatology, University of California, San Francisco, USA
    Am J Dermatopathol 25:162-5. 2003

Collaborators

Detail Information

Publications58

  1. ncbi request reprint What do these cells prove?
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, USA
    Am J Dermatopathol 25:355-6. 2003
  2. ncbi request reprint What genomics has taught me about melanocytic neoplasms
    P E LeBoit
    Department of Pathology and Dermatology, University of California, San Francisco, CA, USA
    G Ital Dermatol Venereol 147:239-49. 2012
    ..Herein are illustrated some pitfalls in the diagnosis of melanoma, as well as variants of Spitz's nevus that correlate with specific genomic aberrations such as gains of chromosome 11p and loss of the BAP-1 gene on chromosome 3p...
  3. doi request reprint What sentinel node biopsy in patients with melanoma (or patients whose doctors worry that they could have melanoma) might and might not do
    Philip E LeBoit
    Department of Pathology, University of California at San Francisco School of Medicine, 1701 Divisadero Street, Suite 350, San Francisco, CA 94115, USA
    Clin Dermatol 27:588-93. 2009
    ..In the setting of a borderline lesion, small nodal deposits must be interpreted with caution...
  4. pmc Use of fluorescence in situ hybridization (FISH) to distinguish intranodal nevus from metastatic melanoma
    Scott R Dalton
    Department of Pathology, Wilford Hall Medical Center, Lackland AFB, TX, USA
    Am J Surg Pathol 34:231-7. 2010
    ..Our data indicate that FISH is a useful adjunct tool to traditional methods in the diagnostic workup of deposits of melanocytes in lymph nodes that are histopathologically ambiguous...
  5. pmc Distribution and significance of occult intraepidermal tumor cells surrounding primary melanoma
    Jeffrey P North
    UCSF School of Medicine, University of California, San Francisco, California, USA
    J Invest Dermatol 128:2024-30. 2008
    ..These field cells provide a plausible explanation for the tendency of certain melanoma types to recur locally despite apparently having undergone complete excision...
  6. ncbi request reprint Seborrheic keratosis with basal clear cells: a distinctive microscopic mimic of melanoma in situ
    Isaac M Neuhaus
    Department of Dermatology, University of California, San Francisco, California, USA
    J Am Acad Dermatol 54:132-5. 2006
    ..We observed seborrheic keratoses with many basilar clear cells, creating a microscopic pattern that mimicked a seborrheic keratosis involved by melanoma in situ...
  7. ncbi request reprint Fluorescence in situ hybridization as an ancillary tool in the diagnosis of ambiguous melanocytic neoplasms: a review of 804 cases
    Jeffrey P North
    Departments of Pathology Dermatology The Helen Diller Comprehensive Cancer Center, University of California, San Francisco, CA
    Am J Surg Pathol 38:824-31. 2014
    ..We conclude that FISH testing can help reduce the number of equivocal diagnoses in ambiguous melanocytic neoplasms, in particular if FISH testing is positive, and discuss the challenges and limitations of FISH in clinical practice. ..
  8. pmc Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomas
    Boris C Bastian
    Department of Dermatology and Pathology, University of California at San Francisco Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 0808, USA
    Am J Pathol 161:1163-9. 2002
    ..This difference compared to the aberration pattern found in melanoma might explain their more benign clinical behavior and may be of diagnostic value in ambiguous cases...
  9. ncbi request reprint Persistent nevus, with "no" previous biopsy
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, USA
    Am J Dermatopathol 26:347-8. 2004
  10. ncbi request reprint Ducking stray "magic bullets": a Melan-A alert
    John C Maize
    Department of Dermatology, University of California, San Francisco, USA
    Am J Dermatopathol 25:162-5. 2003
  11. ncbi request reprint Homonymous epidermotropism
    Philip E LeBoit
    Departments of Pathology and Dermatology, University of California, San Francisco, California, USA
    Am J Dermatopathol 26:81-3. 2004
  12. pmc Classifying melanocytic tumors based on DNA copy number changes
    Boris C Bastian
    Departments of Pathology and Dermatology, Dermatopathology Section, University of California San Francisco, San Francisco, CA 94143 0808, USA
    Am J Pathol 163:1765-70. 2003
    ..In addition, we show marked differences in the genetic make-up of melanomas that depend on anatomical location and sun-exposure pattern indicating that potential therapeutic targets might vary among melanoma types...
  13. ncbi request reprint Approach to the treatment of cutaneous malignancy in HIV-infected patients
    Karl Wilkins
    University of California, San Francisco, USA
    Dermatol Ther 18:77-86. 2005
    ..This article will review and discuss management issues for the following malignancies: lymphomas, malignant melanoma, basal cell carcinoma, squamous cell carcinoma, and Kaposi's sarcoma...
  14. ncbi request reprint What don't we know, and when did we know that we didn't know it?
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, CA, USA
    Am J Dermatopathol 28:89-90. 2006
  15. pmc Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy
    Thomas Botton
    Departments of Dermatology and Pathology and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA
    Pigment Cell Melanoma Res 26:845-51. 2013
    ..The patient from whom the cell line was derived showed a durable clinical response to sorafenib. ..
  16. doi request reprint Melanoma ex blue nevus: two cases resembling large plaque-type blue nevus with subcutaneous cellular nodules
    Jeffrey P North
    Departments of Pathology and Dermatology, University of California, San Francisco, CA, USA
    J Cutan Pathol 39:1094-9. 2012
    ..Molecular techniques can provide valuable insights in these types of difficult melanocytic neoplasms...
  17. doi request reprint Evaluation of imatinib mesylate as a possible treatment for nephrogenic systemic fibrosis in a rat model
    Thomas A Hope
    Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA
    Magn Reson Imaging 31:139-44. 2013
    ..The purpose of the study was to evaluate the efficacy of imatinib mesylate in the treatment of nephrogenic systemic fibrosis (NSF) in a rat model administered high-dose gadodiamide, erythropoietin (Epo) and intravenous iron (IV iron)...
  18. ncbi request reprint Fluorescence in situ hybridization (FISH) as an ancillary diagnostic tool in the diagnosis of melanoma
    Pedram Gerami
    Department of Dermatology and the Lurie Cancer Center, Northwestern University, The Feinberg School of Medicine University of California, San Francisco, CA, USA
    Am J Surg Pathol 33:1146-56. 2009
    ..As a diagnostic aid to traditional histologic evaluation, this assay can have significant clinical impact and improve classification of melanocytic neoplasms with conflicting morphologic criteria...
  19. doi request reprint Subcutaneous panniculitis-like T-cell lymphoma with overlapping clinicopathologic features of lupus erythematosus: coexistence of 2 entities?
    Laura B Pincus
    Departments of Dermatology and daggerPathology, University of California San Francisco, San Francisco, CA, USA
    Am J Dermatopathol 31:520-6. 2009
    ..Additionally, screening for cutaneous LE and SLE could be considered in patients with SPTCL...
  20. doi request reprint Selection of tumorigenic melanoma cells using ALDH
    Jim B Boonyaratanakornkit
    Department of Dermatology, University of California, San Francisco, San Francisco, California, USA
    J Invest Dermatol 130:2799-808. 2010
    ..Thus, ALDH(+) melanoma cells have enhanced tumorigenicity over ALDH(-) cells and superior self-renewal ability...
  21. ncbi request reprint Distinct sets of genetic alterations in melanoma
    John A Curtin
    Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143 0808, USA
    N Engl J Med 353:2135-47. 2005
    ..We hypothesized that the clinical heterogeneity is explained by genetically distinct types of melanoma with different susceptibility to ultraviolet light...
  22. ncbi request reprint Perifollicular xanthomatosis as the hallmark of axillary Fox-Fordyce disease: an evaluation of histopathologic features of 7 cases
    Adolfo B Bormate
    Section of Dermatopathology, Department of Pathology, University of California, San Francisco, 1701 Divisadero St, San Francisco, CA 94115, USA
    Arch Dermatol 144:1020-4. 2008
    ..In this study, we evaluated both established and new histopathologic criteria for the diagnosis of FFD and searched for other meaningful findings...
  23. pmc Metastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanoma
    John R Jalas
    Department of Pathology, University of California at San Francisco, San Francisco, CA, USA
    Am J Surg Pathol 35:1413-8. 2011
    ..Our findings illustrate the ability of molecular analyses to resolve lineage in complex neoplasms and illustrate the phenotypic plasticity of cancer cells...
  24. ncbi request reprint Fibroepithelioma of pinkus is a fenestrated trichoblastoma
    Anneli R Bowen
    Department of Pathology, University of California, San Francisco, CA 94115, USA
    Am J Dermatopathol 27:149-54. 2005
    ..Given the contrast between FEP and BCC with respect to site of occurrence, relationship to sun damage, histopathologic features, and immunohistochemical studies, it appears that FEP more closely resembles trichoblastoma than BCC...
  25. ncbi request reprint Pictures of a unicorn?
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, 94115, USA
    Am J Dermatopathol 25:88-91. 2003
  26. ncbi request reprint Lymphomatoid papulosis associated with mycosis fungoides: a study of 21 patients including analyses for clonality
    Herschel S Zackheim
    Department of Dermatology, University of California, San Francisco, CA, USA
    J Am Acad Dermatol 49:620-3. 2003
    ..Although an association of lymphomatoid papulosis (LyP) with mycosis fungoides (MF) is recognized, our understanding of this relation is limited...
  27. ncbi request reprint "Safe" Spitz and its alternatives
    Philip E LeBoit
    Department of Pathology, University of California at San Francisco, California 94115, USA
    Pediatr Dermatol 19:163-5. 2002
  28. ncbi request reprint Dust to dust
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, California
    Am J Dermatopathol 27:277-8. 2005
  29. doi request reprint Marked papillary dermal edema--an unreliable discriminator between polymorphous light eruption and lupus erythematosus or dermatomyositis
    Laura B Pincus
    Department of Pathology, University of California, San Francisco, San Francisco, CA 94115, USA
    J Cutan Pathol 37:416-25. 2010
    ..Older reports also describe papillary dermal edema in microscopic sections of dermatomyositis (DM)...
  30. ncbi request reprint Granuloma faciale: a diagnosis deserving of dignity
    Philip E LeBoit
    Department of Pathology, University of California San Francisco, California 94115, USA
    Am J Dermatopathol 24:440-3. 2002
  31. ncbi request reprint Cutaneous malignancy and human immunodeficiency virus disease
    Karl Wilkins
    Department of Dermatology, University of California San Francisco, California, USA
    J Am Acad Dermatol 54:189-206; quiz 207-10. 2006
    ..Other types of cutaneous lymphoma and HIV-associated pseudo-CTCL are discussed. This article addresses prevention, treatment, and follow-up strategies for this at-risk population...
  32. ncbi request reprint Vasculitis: The true and the near-true
    Philip E LeBoit
    Departments of Pathology and Dermatology, University of California, San Francisco, California 94115, USA
    Am J Dermatopathol 24:267-9. 2002
  33. ncbi request reprint Can we understand keratoacanthoma?
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, California 94115, USA
    Am J Dermatopathol 24:166-8. 2002
  34. doi request reprint SOX-10 expression in cutaneous myoepitheliomas and mixed tumors
    Agne Naujokas
    Department of Pathology, University of California, San Francisco, CA, USA
    J Cutan Pathol 41:353-63. 2014
    ..SOX-10 expression can be demonstrated by immunohistochemistry in salivary gland myoepitheliomas, but its expression in cutaneous myoepitheliomas and in cutaneous mixed tumors with prominent myoepithelial cells has not been studied...
  35. ncbi request reprint Melanosis and its meanings
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, California, USA
    Am J Dermatopathol 24:369-72. 2002
  36. ncbi request reprint "Magic bullets" in immunohistochemistry
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco 94115, USA
    Am J Dermatopathol 24:518-20. 2002
  37. ncbi request reprint Persistent (recurrent) Spitz nevi: a histopathologic, immunohistochemical, and molecular pathologic study of 22 cases
    Jeff D Harvell
    Department of Pathology, Stanford University Medical Center, Stanford, California, USA
    Am J Surg Pathol 26:654-61. 2002
    ..Although ancillary molecular techniques such as CGH are of great help in distinguishing these from melanoma, until such techniques become widely available we advocate complete but conservative excision of any recurrent Spitz nevus...
  38. ncbi request reprint Interstitial mycosis fungoides, a variant of mycosis fungoides resembling granuloma annulare and inflammatory morphea
    Lyndon D Su
    Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
    J Cutan Pathol 29:135-41. 2002
    ..Interstitial mycosis fungoides (IMF) is a rare variant of mycosis fungoides that resembles the interstitial form of granuloma annulare and inflammatory morphea. IMF has received little attention in the literature...
  39. doi request reprint Squamous cell carcinoma with clear cells: how often is there evidence of tricholemmal differentiation?
    Scott R Dalton
    Department of Pathology, Wilford Hall Medical Center, Lackland, AFB, TX, USA
    Am J Dermatopathol 30:333-9. 2008
    ..Thus, we also conclude that well-differentiated TC is rare and its description in the literature may overstate the case that it is a well-characterized cutaneous neoplasm...
  40. ncbi request reprint Trichoblastoma, basal cell carcinoma, and follicular differentiation: what should we trust?
    Philip E LeBoit
    Department of Pathology and Dermatology, University of California San Francisco, San Francisco, CA, USA
    Am J Dermatopathol 25:260-3. 2003
  41. ncbi request reprint Does this Res Ipse Loquitur?
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, USA
    Am J Dermatopathol 27:372-3. 2005
  42. ncbi request reprint Provocative globules in a "seb"
    Philip E LeBoit
    Departments of Pathology and Dermatology, University of California, San Francisco, USA
    Am J Dermatopathol 25:500-1. 2003
  43. ncbi request reprint Histomorphologic Assessment and Interobserver Diagnostic Reproducibility of Atypical Spitzoid Melanocytic Neoplasms With Long-term Follow-up
    Pedram Gerami
    Department of Dermatology Robert H Lurie Cancer Center Department of Preventive Medicine and the Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Il Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY Department of Pathology and Laboratory Medicine, Dermatopathology, UCLA Medical Center, Los Angeles Departments of Pathology and Dermatology, University of California, San Francisco, San Francisco, CA Pathology Service, Massachusetts General Hospital, Boston, MA Department of Pathology, University of Pennsylvania, Philadelphia Rabkin Dermatopathology Laboratory, P C, Tarentum, PA Departments of Pathology Dermatology, University of Michigan Medical Center, Ann Arbor, MI Department of Pathology, Section of Dermatopathology Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX Department of Histopathology, Royal Surrey County Hospital and Division of Clinical Medicine, University of Surrey, Guildford, Surrey, UK Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Melanoma Institute Australia and The University of Sydney, NSW, Australia Departments of Dermatology, Chonnam National University Medical School, Gwangju, Korea
    Am J Surg Pathol 38:934-40. 2014
    ..This study may provide some guidance regarding histologic assessment of these enigmatic tumors. ..
  44. pmc Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo
    Christian Posch
    Department of Dermatology, Mount Zion Cancer Research Center, San Francisco, CA 94115, USA
    Proc Natl Acad Sci U S A 110:4015-20. 2013
    ....
  45. ncbi request reprint Slouching toward the lymphatic lumen
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, USA
    Am J Dermatopathol 27:548-50. 2005
  46. ncbi request reprint What goes down can go up
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, California, USA
    Am J Dermatopathol 27:89-90. 2005
  47. ncbi request reprint Etiology of pruritic papular eruption with HIV infection in Uganda
    Jack S Resneck
    Department of Dermatology and Institute for Health Policy Studies, University of California, San Francisco, School of Medicine, CA 94143 0363, USA
    JAMA 292:2614-21. 2004
    ..The resulting scars are disfiguring and stigmatizing. Despite the substantial prevalence of pruritic papular eruption (PPE) among HIV-infected Africans, the cause has been elusive...
  48. ncbi request reprint Cutaneous lymphocytic infiltrates: let's get real
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, California, USA
    Am J Dermatopathol 27:182-4. 2005
  49. ncbi request reprint Alopecia mucinosa, inflammatory disease or mycosis fungoides: must we choose? And are there other choices?
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, CA, USA
    Am J Dermatopathol 26:167-70. 2004
  50. ncbi request reprint Through a lens darkly
    Philip E LeBoit
    Department of Pathology and Dermatology, University of California, San Francisco, CA, USA
    Am J Dermatopathol 28:279-81. 2006
  51. ncbi request reprint Crushed expectations
    Philip E LeBoit
    Departments of Pathology, University of California, San Francisco, California, USA
    Am J Dermatopathol 27:466-7. 2005
  52. ncbi request reprint Margin call
    Philip E LeBoit
    Depts of Pathology and Dermatology, University of California, San Francisco, USA
    Am J Dermatopathol 26:259-62. 2004
  53. ncbi request reprint The last refuge of scoundrels
    Philip E LeBoit
    Departments of Pathology and Dermatology, University of California, San Francisco, USA
    Am J Dermatopathol 26:516-7. 2004
  54. doi request reprint Eosinophils in mycosis fungoides: an uncommon finding in the patch and plaque stages
    Scott R Dalton
    Department of Dermatology, Geisinger Medical Center, Danville, PA 17821, USA
    Am J Dermatopathol 34:586-91. 2012
    ..However, in cases where fewer than 3 eosinophils are present in sections, patch stage MF cannot be excluded...
  55. ncbi request reprint A testable hypothesis in a "borderline" neoplasm
    Philip E LeBoit
    Departments of Pathology and Dermatology, University of California, San Francisco, California, USA
    Am J Dermatopathol 24:89-91. 2002
  56. ncbi request reprint The thin brown line
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, California, USA
    Am J Dermatopathol 26:444-5. 2004
  57. ncbi request reprint Lessons from lumps
    Philip E LeBoit
    Department of Pathology, University of California, San Francisco, CA, USA
    Am J Dermatopathol 25:443-4. 2003
  58. doi request reprint Nephrogenic systemic fibrosis in rats treated with erythropoietin and intravenous iron
    Thomas A Hope
    Department of Radiology, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA 94143, USA
    Radiology 253:390-8. 2009
    ....