Research Topics
| Philip E LeBoitSummaryAffiliation: University of California Country: USA Publications
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Publications
What do these cells prove?Philip E LeBoit
Department of Pathology, University of California, San Francisco, USA
Am J Dermatopathol 25:355-6. 2003- What genomics has taught me about melanocytic neoplasmsP E LeBoit
Department of Pathology and Dermatology, University of California, San Francisco, CA, USA
G Ital Dermatol Venereol 147:239-49. 2012..Herein are illustrated some pitfalls in the diagnosis of melanoma, as well as variants of Spitz's nevus that correlate with specific genomic aberrations such as gains of chromosome 11p and loss of the BAP-1 gene on chromosome 3p... 
What sentinel node biopsy in patients with melanoma (or patients whose doctors worry that they could have melanoma) might and might not doPhilip E LeBoit
Department of Pathology, University of California at San Francisco School of Medicine, 1701 Divisadero Street, Suite 350, San Francisco, CA 94115, USA
Clin Dermatol 27:588-93. 2009..In the setting of a borderline lesion, small nodal deposits must be interpreted with caution...
Use of fluorescence in situ hybridization (FISH) to distinguish intranodal nevus from metastatic melanomaScott R Dalton
Department of Pathology, Wilford Hall Medical Center, Lackland AFB, TX, USA
Am J Surg Pathol 34:231-7. 2010..Our data indicate that FISH is a useful adjunct tool to traditional methods in the diagnostic workup of deposits of melanocytes in lymph nodes that are histopathologically ambiguous...- Distribution and significance of occult intraepidermal tumor cells surrounding primary melanomaJeffrey P North
UCSF School of Medicine, University of California, San Francisco, California, USA
J Invest Dermatol 128:2024-30. 2008..These field cells provide a plausible explanation for the tendency of certain melanoma types to recur locally despite apparently having undergone complete excision... - Seborrheic keratosis with basal clear cells: a distinctive microscopic mimic of melanoma in situIsaac M Neuhaus
Department of Dermatology, University of California, San Francisco, California, USA
J Am Acad Dermatol 54:132-5. 2006..Careful conventional microscopy coupled with a panel of immunostains can allow the proper diagnosis to be reached... - Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomasBoris C Bastian
Department of Dermatology and Pathology, University of California at San Francisco Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 0808, USA
Am J Pathol 161:1163-9. 2002..This difference compared to the aberration pattern found in melanoma might explain their more benign clinical behavior and may be of diagnostic value in ambiguous cases... - Homonymous epidermotropismPhilip E LeBoit
Departments of Pathology and Dermatology, University of California, San Francisco, California, USA
Am J Dermatopathol 26:81-3. 2004 - Approach to the treatment of cutaneous malignancy in HIV-infected patientsKarl Wilkins
University of California, San Francisco, USA
Dermatol Ther 18:77-86. 2005..This article will review and discuss management issues for the following malignancies: lymphomas, malignant melanoma, basal cell carcinoma, squamous cell carcinoma, and Kaposi's sarcoma... - Persistent nevus, with "no" previous biopsyPhilip E LeBoit
Department of Pathology, University of California, San Francisco, USA
Am J Dermatopathol 26:347-8. 2004 - Classifying melanocytic tumors based on DNA copy number changesBoris C Bastian
Departments of Pathology and Dermatology, Dermatopathology Section, University of California San Francisco, San Francisco, CA 94143 0808, USA
Am J Pathol 163:1765-70. 2003..In addition, we show marked differences in the genetic make-up of melanomas that depend on anatomical location and sun-exposure pattern indicating that potential therapeutic targets might vary among melanoma types... - Ducking stray "magic bullets": a Melan-A alertJohn C Maize
Department of Dermatology, University of California, San Francisco, USA
Am J Dermatopathol 25:162-5. 2003 - What don't we know, and when did we know that we didn't know it?Philip E LeBoit
Department of Pathology, University of California, San Francisco, CA, USA
Am J Dermatopathol 28:89-90. 2006 - Distinct sets of genetic alterations in melanomaJohn A Curtin
Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143-0808, USA
N Engl J Med 353:2135-47. 2005.... - Fluorescence in situ hybridization (FISH) as an ancillary diagnostic tool in the diagnosis of melanomaPedram Gerami
Department of Dermatology and the Lurie Cancer Center, Northwestern University, The Feinberg School of Medicine University of California, San Francisco, CA, USA
Am J Surg Pathol 33:1146-56. 2009..As a diagnostic aid to traditional histologic evaluation, this assay can have significant clinical impact and improve classification of melanocytic neoplasms with conflicting morphologic criteria... - Subcutaneous panniculitis-like T-cell lymphoma with overlapping clinicopathologic features of lupus erythematosus: coexistence of 2 entities?Laura B Pincus
Departments of Dermatology and daggerPathology, University of California San Francisco, San Francisco, CA, USA
Am J Dermatopathol 31:520-6. 2009..Additionally, screening for cutaneous LE and SLE could be considered in patients with SPTCL... - Selection of tumorigenic melanoma cells using ALDHJim B Boonyaratanakornkit
Department of Dermatology, University of California, San Francisco, San Francisco, California, USA
J Invest Dermatol 130:2799-808. 2010..Thus, ALDH(+) melanoma cells have enhanced tumorigenicity over ALDH(-) cells and superior self-renewal ability... - Perifollicular xanthomatosis as the hallmark of axillary Fox-Fordyce disease: an evaluation of histopathologic features of 7 casesAdolfo B Bormate
Section of Dermatopathology, Department of Pathology, University of California, San Francisco, 1701 Divisadero St, San Francisco, CA 94115, USA
Arch Dermatol 144:1020-4. 2008..In this study, we evaluated both established and new histopathologic criteria for the diagnosis of FFD and searched for other meaningful findings... - Dust to dustPhilip E LeBoit
Department of Pathology, University of California, San Francisco, California
Am J Dermatopathol 27:277-8. 2005 - Fibroepithelioma of pinkus is a fenestrated trichoblastomaAnneli R Bowen
Department of Pathology, University of California, San Francisco, CA 94115, USA
Am J Dermatopathol 27:149-54. 2005..Given the contrast between FEP and BCC with respect to site of occurrence, relationship to sun damage, histopathologic features, and immunohistochemical studies, it appears that FEP more closely resembles trichoblastoma than BCC... - Metastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanomaJohn R Jalas
Department of Pathology, University of California at San Francisco, San Francisco, CA, USA
Am J Surg Pathol 35:1413-8. 2011..Our findings illustrate the ability of molecular analyses to resolve lineage in complex neoplasms and illustrate the phenotypic plasticity of cancer cells... - "Safe" Spitz and its alternativesPhilip E LeBoit
Department of Pathology, University of California at San Francisco, California 94115, USA
Pediatr Dermatol 19:163-5. 2002 - Marked papillary dermal edema--an unreliable discriminator between polymorphous light eruption and lupus erythematosus or dermatomyositisLaura B Pincus
Department of Pathology, University of California, San Francisco, San Francisco, CA 94115, USA
J Cutan Pathol 37:416-25. 2010..Older reports also describe papillary dermal edema in microscopic sections of dermatomyositis (DM)... - Pictures of a unicorn?Philip E LeBoit
Department of Pathology, University of California, San Francisco, 94115, USA
Am J Dermatopathol 25:88-91. 2003 - Lymphomatoid papulosis associated with mycosis fungoides: a study of 21 patients including analyses for clonalityHerschel S Zackheim
Department of Dermatology, University of California, San Francisco, CA, USA
J Am Acad Dermatol 49:620-3. 2003..Although an association of lymphomatoid papulosis (LyP) with mycosis fungoides (MF) is recognized, our understanding of this relation is limited... - Vasculitis: The true and the near-truePhilip E LeBoit
Departments of Pathology and Dermatology, University of California, San Francisco, California 94115, USA
Am J Dermatopathol 24:267-9. 2002 - Granuloma faciale: a diagnosis deserving of dignityPhilip E LeBoit
Department of Pathology, University of California San Francisco, California 94115, USA
Am J Dermatopathol 24:440-3. 2002 - Cutaneous malignancy and human immunodeficiency virus diseaseKarl Wilkins
Department of Dermatology, University of California San Francisco, California, USA
J Am Acad Dermatol 54:189-206; quiz 207-10. 2006..LEARNING OBJECTIVE: At the completion of this learning activity, participants should be familiar with the unique epidemiology, clinical course, and management of cutaneous malignancy in patients infected with HIV... - Can we understand keratoacanthoma?Philip E LeBoit
Department of Pathology, University of California, San Francisco, California 94115, USA
Am J Dermatopathol 24:166-8. 2002 - Evaluation of imatinib mesylate as a possible treatment for nephrogenic systemic fibrosis in a rat modelThomas A Hope
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA
Magn Reson Imaging 31:139-44. 2013..The purpose of the study was to evaluate the efficacy of imatinib mesylate in the treatment of nephrogenic systemic fibrosis (NSF) in a rat model administered high-dose gadodiamide, erythropoietin (Epo) and intravenous iron (IV iron)... - Squamous cell carcinoma with clear cells: how often is there evidence of tricholemmal differentiation?Scott R Dalton
Department of Pathology, Wilford Hall Medical Center, Lackland, AFB, TX, USA
Am J Dermatopathol 30:333-9. 2008..Thus, we also conclude that well-differentiated TC is rare and its description in the literature may overstate the case that it is a well-characterized cutaneous neoplasm... - "Magic bullets" in immunohistochemistryPhilip E LeBoit
Department of Pathology, University of California, San Francisco 94115, USA
Am J Dermatopathol 24:518-20. 2002 - Does this Res Ipse Loquitur?Philip E LeBoit
Department of Pathology, University of California, San Francisco, USA
Am J Dermatopathol 27:372-3. 2005 - Persistent (recurrent) Spitz nevi: a histopathologic, immunohistochemical, and molecular pathologic study of 22 casesJeff D Harvell
Department of Pathology, Stanford University Medical Center, Stanford, California, USA
Am J Surg Pathol 26:654-61. 2002..Although ancillary molecular techniques such as CGH are of great help in distinguishing these from melanoma, until such techniques become widely available we advocate complete but conservative excision of any recurrent Spitz nevus... - Melanosis and its meaningsPhilip E LeBoit
Department of Pathology, University of California, San Francisco, California, USA
Am J Dermatopathol 24:369-72. 2002 - Provocative globules in a "seb"Philip E LeBoit
Departments of Pathology and Dermatology, University of California, San Francisco, USA
Am J Dermatopathol 25:500-1. 2003 - Interstitial mycosis fungoides, a variant of mycosis fungoides resembling granuloma annulare and inflammatory morpheaLyndon D Su
Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
J Cutan Pathol 29:135-41. 2002..Interstitial mycosis fungoides (IMF) is a rare variant of mycosis fungoides that resembles the interstitial form of granuloma annulare and inflammatory morphea. IMF has received little attention in the literature... - Trichoblastoma, basal cell carcinoma, and follicular differentiation: what should we trust?Philip E LeBoit
Department of Pathology and Dermatology, University of California San Francisco, San Francisco, CA, USA
Am J Dermatopathol 25:260-3. 2003 - Melanoma ex blue nevus: two cases resembling large plaque-type blue nevus with subcutaneous cellular nodulesJeffrey P North
Departments of Pathology and Dermatology, University of California, San Francisco, CA, USA
J Cutan Pathol 39:1094-9. 2012..Molecular techniques can provide valuable insights in these types of difficult melanocytic neoplasms... - Through a lens darklyPhilip E LeBoit
Department of Pathology and Dermatology, University of California, San Francisco, CA, USA
Am J Dermatopathol 28:279-81. 2006 - Etiology of pruritic papular eruption with HIV infection in UgandaJack S Resneck
Department of Dermatology and Institute for Health Policy Studies, University of California, San Francisco, School of Medicine, CA 94143 0363, USA
JAMA 292:2614-21. 2004..The resulting scars are disfiguring and stigmatizing. Despite the substantial prevalence of pruritic papular eruption (PPE) among HIV-infected Africans, the cause has been elusive... - The last refuge of scoundrelsPhilip E LeBoit
Departments of Pathology and Dermatology, University of California, San Francisco, USA
Am J Dermatopathol 26:516-7. 2004 - What goes down can go upPhilip E LeBoit
Department of Pathology, University of California, San Francisco, California, USA
Am J Dermatopathol 27:89-90. 2005 - Cutaneous lymphocytic infiltrates: let's get realPhilip E LeBoit
Department of Pathology, University of California, San Francisco, California, USA
Am J Dermatopathol 27:182-4. 2005 - Crushed expectationsPhilip E LeBoit
Departments of Pathology, University of California, San Francisco, California, USA
Am J Dermatopathol 27:466-7. 2005 - Margin callPhilip E LeBoit
Depts. of Pathology and Dermatology, University of California, San Francisco, USA
Am J Dermatopathol 26:259-62. 2004 - Slouching toward the lymphatic lumenPhilip E LeBoit
Department of Pathology, University of California, San Francisco, USA
Am J Dermatopathol 27:548-50. 2005 - Alopecia mucinosa, inflammatory disease or mycosis fungoides: must we choose? And are there other choices?Philip E LeBoit
Department of Pathology, University of California, San Francisco, CA, USA
Am J Dermatopathol 26:167-70. 2004 - Eosinophils in mycosis fungoides: an uncommon finding in the patch and plaque stagesScott R Dalton
Department of Dermatology, Geisinger Medical Center, Danville, PA 17821, USA
Am J Dermatopathol 34:586-91. 2012..However, in cases where fewer than 3 eosinophils are present in sections, patch stage MF cannot be excluded... - Lessons from lumpsPhilip E LeBoit
Department of Pathology, University of California, San Francisco, CA, USA
Am J Dermatopathol 25:443-4. 2003 - Nephrogenic systemic fibrosis in rats treated with erythropoietin and intravenous ironThomas A Hope
Department of Radiology, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA 94143, USA
Radiology 253:390-8. 2009.... - A testable hypothesis in a "borderline" neoplasmPhilip E LeBoit
Departments of Pathology and Dermatology, University of California, San Francisco, California, USA
Am J Dermatopathol 24:89-91. 2002 - The thin brown linePhilip E LeBoit
Department of Pathology, University of California, San Francisco, California, USA
Am J Dermatopathol 26:444-5. 2004