TUCKER LEBIEN

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi B lymphocytes: how they develop and function
    Tucker W Lebien
    Department of Laboratory Medicine Pathology, University of Minnesota Cancer Center, Minneapolis, MN 55455, USA
    Blood 112:1570-80. 2008
  2. ncbi Arginine: an unusual dietary requirement of pre-B lymphocytes?
    Tucker W Lebien
    Department of Laboratory Medicine and Pathology, University of Minnesota Cancer Center, Minneapolis, Minnesota 55455, USA
    J Clin Invest 110:1411-3. 2002
  3. ncbi Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells
    Sonja E Johnson
    The Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 175:7325-31. 2005
  4. ncbi Enhancement of stress-induced apoptosis in B-lineage cells by caspase-9 inhibitor
    Nisha Shah
    Cancer Center and Department of Laboratory Medicine/Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Blood 104:2873-8. 2004
  5. ncbi IL-7 activates the phosphatidylinositol 3-kinase/AKT pathway in normal human thymocytes but not normal human B cell precursors
    Sonja E Johnson
    The Masonic Cancer Center and Department of Laboratory Medicine Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 180:8109-17. 2008

Research Grants

  1. DIFFERENTIATIVE PROGRAMS OF LYMPHOID PROGENITOR CELLS
    TUCKER LEBIEN; Fiscal Year: 2004
  2. MEDICAL SCIENTIST TRAINING PROGRAM
    TUCKER LEBIEN; Fiscal Year: 2007
  3. DIFFERENTIATIVE PROGRAMS OF LYMPHOID PROGENITOR CELLS
    TUCKER LEBIEN; Fiscal Year: 1993
  4. DIFFERENTIATIVE PROGRAMS OF LYMPHOID PROGENITOR CELLS
    TUCKER LEBIEN; Fiscal Year: 1999

Collaborators

  • Thomas Tedder
  • Sonja E Johnson
  • Nisha Shah
  • Anna A Bajer
  • Angela Panoskaltsis-Mortari
  • Alana S Lysholm
  • Rebecca J Asch

Detail Information

Publications5

  1. ncbi B lymphocytes: how they develop and function
    Tucker W Lebien
    Department of Laboratory Medicine Pathology, University of Minnesota Cancer Center, Minneapolis, MN 55455, USA
    Blood 112:1570-80. 2008
    ..Despite the significant advances that have been made at the cellular and molecular levels, there is much more to learn, and cross-disciplinary studies in hematology and immunology will continue to pave the way for new discoveries...
  2. ncbi Arginine: an unusual dietary requirement of pre-B lymphocytes?
    Tucker W Lebien
    Department of Laboratory Medicine and Pathology, University of Minnesota Cancer Center, Minneapolis, Minnesota 55455, USA
    J Clin Invest 110:1411-3. 2002
  3. ncbi Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells
    Sonja E Johnson
    The Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 175:7325-31. 2005
    ..Our results support a model wherein IL-7 transduces a replicative signal to normal human B-lineage cells that is complemented by additional stromal cell-derived signals essential for normal human B cell development...
  4. ncbi Enhancement of stress-induced apoptosis in B-lineage cells by caspase-9 inhibitor
    Nisha Shah
    Cancer Center and Department of Laboratory Medicine/Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Blood 104:2873-8. 2004
    ..These collective results suggest that a 4-amino acid caspase inhibitor of caspase-9 can promote apoptosis and that at least some types of apoptotic pathways in B-lineage ALL do not require caspase-9...
  5. ncbi IL-7 activates the phosphatidylinositol 3-kinase/AKT pathway in normal human thymocytes but not normal human B cell precursors
    Sonja E Johnson
    The Masonic Cancer Center and Department of Laboratory Medicine Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 180:8109-17. 2008
    ..The different induction of PI3K/AKT may at least partially explain the different requirements for IL-7 during human T and B cell development...

Research Grants29

  1. DIFFERENTIATIVE PROGRAMS OF LYMPHOID PROGENITOR CELLS
    TUCKER LEBIEN; Fiscal Year: 2004
    ..The collective results from these studies will enhance our understanding of the normal developmental program of human B lymphocytes and perturbations in the program that can give rise to leukemia and immunodeficiency. ..
  2. MEDICAL SCIENTIST TRAINING PROGRAM
    TUCKER LEBIEN; Fiscal Year: 2007
    ....
  3. DIFFERENTIATIVE PROGRAMS OF LYMPHOID PROGENITOR CELLS
    TUCKER LEBIEN; Fiscal Year: 1993
    ..4) Studies are underway to clone the genes encoding gp40/BA-1, p24/BA-2, and gp/100/CACCA/BA-3 using mouse L cell transfection and subtractive hybridization. (LB) ..
  4. DIFFERENTIATIVE PROGRAMS OF LYMPHOID PROGENITOR CELLS
    TUCKER LEBIEN; Fiscal Year: 1999
    ....