Andrew D Leavitt

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720
    Tamihiro Kamata
    Department of Laboratory Medicine, University of California, San Francisco, 513 Parnassus Ave, Room S 561, San Francisco, CA 94143 0100
    Mol Cancer Res 11:1530-41. 2013
  2. doi Homologous recombination in human embryonic stem cells: a tool for advancing cell therapy and understanding and treating human disease
    Andrew D Leavitt
    Laboratory Medicine, University of California, San Francisco, California, USA
    Clin Transl Sci 4:298-305. 2011
  3. pmc Are there more tricks in the bag for treating thrombocytopenia?
    Andrew D Leavitt
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California 94143 0100, USA
    J Clin Invest 120:3807-10. 2010
  4. pmc A critical function for B-Raf at multiple stages of myelopoiesis
    Tamihiro Kamata
    Department of Laboratory Medicine, University of California, San Francisco, 513 Parnassus Ave, Room S 577, San Francisco, CA 94143 0100, USA
    Blood 106:833-40. 2005
  5. ncbi Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation
    Tamihiro Kamata
    Department of Laboratory Medicine, University of California, San Francisco, CA 94143 0100, USA
    Blood 103:2568-70. 2004
  6. pmc Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures
    Frank W King
    Cardiovascular Research Institute, University of California, San Francisco, CA 94143 1346, USA
    Stem Cells Dev 18:1441-50. 2009
  7. ncbi A method for single-cell sorting and expansion of genetically modified human embryonic stem cells
    Cory R Nicholas
    Human Embryonic Stem Cell Center, Department of Obstetrics, Gynecology and Reproductive Sciences, San Francisco, CA 94143 0556, USA
    Stem Cells Dev 16:109-17. 2007
  8. ncbi Using retroviruses to express genes in primary megakaryocyte lineage cells
    Meenakshi Gaur
    Department of Laboratory and Internal Medicine, University of California, San Franciso, CA, USA
    Methods Mol Biol 273:381-96. 2004
  9. ncbi Caspase-12: a developmental link between G-protein-coupled receptors and integrin alphaIIbbeta3 activation
    Steven W Kerrigan
    Department of Laboratory Medicine, University of California San Francisco, 513 Parnassus Ave, Rm S 577, San Francisco, CA 94143 0100, USA
    Blood 104:1327-34. 2004
  10. doi Prolonged ceftriaxone-induced immune thrombocytopenia due to impaired drug clearance: a case report
    Cyril Jacquot
    Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California Department of Internal Medicine, University of California at San Francisco, San Francisco, California Clinical Laboratory, San Francisco General Hospital, San Francisco, California Blood Centers of the Pacific, San Francisco, California
    Transfusion 53:2715-21. 2013

Collaborators

Detail Information

Publications10

  1. pmc Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720
    Tamihiro Kamata
    Department of Laboratory Medicine, University of California, San Francisco, 513 Parnassus Ave, Room S 561, San Francisco, CA 94143 0100
    Mol Cancer Res 11:1530-41. 2013
    ..Taken together, these results provide evidence that constitutively activated BRAF(V600E) drives aberrant proliferation of monocyte-lineage cells...
  2. doi Homologous recombination in human embryonic stem cells: a tool for advancing cell therapy and understanding and treating human disease
    Andrew D Leavitt
    Laboratory Medicine, University of California, San Francisco, California, USA
    Clin Transl Sci 4:298-305. 2011
    ..Herein, we review the current status of homologous recombination in hESCs, a gene targeting technique that is sure to continue to improve, and to play an important role in realizing the maximal human benefit from hESCs...
  3. pmc Are there more tricks in the bag for treating thrombocytopenia?
    Andrew D Leavitt
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California 94143 0100, USA
    J Clin Invest 120:3807-10. 2010
    ..In this issue of the JCI, Fuentes et al. present provocative data regarding the use of direct megakaryocyte infusions as a novel approach to manage this vexing clinical problem...
  4. pmc A critical function for B-Raf at multiple stages of myelopoiesis
    Tamihiro Kamata
    Department of Laboratory Medicine, University of California, San Francisco, 513 Parnassus Ave, Room S 577, San Francisco, CA 94143 0100, USA
    Blood 106:833-40. 2005
    ..Together, these data suggest that B-Raf plays a cell-autonomous role in megakaryocytopoiesis and a permissive role in myeloid progenitor development...
  5. ncbi Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation
    Tamihiro Kamata
    Department of Laboratory Medicine, University of California, San Francisco, CA 94143 0100, USA
    Blood 103:2568-70. 2004
    ..These unexpected findings demonstrate that Raf-1 is dispensable for megakaryocytopoiesis, and for thrombopoietin-induced ERK1/2 activation in primary megakaryocyte-lineage cells...
  6. pmc Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures
    Frank W King
    Cardiovascular Research Institute, University of California, San Francisco, CA 94143 1346, USA
    Stem Cells Dev 18:1441-50. 2009
    ..This co-culture approach also will enable identification of other distinct hESC subpopulations, and selection for these should prove valuable in generating tissue-specific reagents for cell-based therapy...
  7. ncbi A method for single-cell sorting and expansion of genetically modified human embryonic stem cells
    Cory R Nicholas
    Human Embryonic Stem Cell Center, Department of Obstetrics, Gynecology and Reproductive Sciences, San Francisco, CA 94143 0556, USA
    Stem Cells Dev 16:109-17. 2007
    ....
  8. ncbi Using retroviruses to express genes in primary megakaryocyte lineage cells
    Meenakshi Gaur
    Department of Laboratory and Internal Medicine, University of California, San Franciso, CA, USA
    Methods Mol Biol 273:381-96. 2004
  9. ncbi Caspase-12: a developmental link between G-protein-coupled receptors and integrin alphaIIbbeta3 activation
    Steven W Kerrigan
    Department of Laboratory Medicine, University of California San Francisco, 513 Parnassus Ave, Rm S 577, San Francisco, CA 94143 0100, USA
    Blood 104:1327-34. 2004
    ....
  10. doi Prolonged ceftriaxone-induced immune thrombocytopenia due to impaired drug clearance: a case report
    Cyril Jacquot
    Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California Department of Internal Medicine, University of California at San Francisco, San Francisco, California Clinical Laboratory, San Francisco General Hospital, San Francisco, California Blood Centers of the Pacific, San Francisco, California
    Transfusion 53:2715-21. 2013
    ..Therefore, platelet (PLT) counts often start to recover 1 to 2 days after discontinuation of the offending medication. We present a case of ceftriaxone-induced DIT that resulted in severe, prolonged thrombocytopenia...