Loic Le Marchand

Summary

Affiliation: University of Hawaii
Country: USA

Publications

  1. request reprint
    Le Marchand L, Donlon T, Seifried A, Kaaks R, Rinaldi S, Wilkens L. Association of a common polymorphism in the human GH1 gene with colorectal neoplasia. J Natl Cancer Inst. 2002;94:454-60 pubmed
    ..01). The human T1663A GH1 gene polymorphism, which may confer lower levels of GH and IGF-I, appears to be associated with a decreased risk of colorectal cancer. ..
  2. request reprint
    Le Marchand L, Donlon T, Kolonel L, Henderson B, Wilkens L. Estrogen metabolism-related genes and breast cancer risk: the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev. 2005;14:1998-2003 pubmed
    ..They also provide support for an inverse association between CYP1A2*1F and breast cancer, which is consistent with the observation of lower circulating estrogen levels in premenopausal women with the CC genotype in a previous study. ..
  3. Le Marchand L, Wang H, Rinaldi S, Kaaks R, Vogt T, Yokochi L, et al. Associations of plasma C-peptide and IGFBP-1 levels with risk of colorectal adenoma in a multiethnic population. Cancer Epidemiol Biomarkers Prev. 2010;19:1471-7 pubmed publisher
    ..This study suggests that hyperinsulinemia and IGF hormones may act as etiologic factors in colorectal carcinogenesis, as early as during adenoma formation. ..
  4. Petridis C, Brook M, Shah V, Kohut K, Gorman P, Caneppele M, et al. Genetic predisposition to ductal carcinoma in situ of the breast. Breast Cancer Res. 2016;18:22 pubmed publisher
    ..0x10(-8). In conclusion, this study provides the strongest evidence to date of a shared genetic susceptibility for IDC and DCIS. Studies with larger numbers of DCIS are needed to determine if IDC or DCIS specific loci exist. ..
  5. Haiman C, Garcia R, Hsu C, Xia L, Ha H, Sheng X, et al. Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. BMC Cancer. 2009;9:43 pubmed publisher
    ....

Locale

Detail Information

Publications5

  1. request reprint
    Le Marchand L, Donlon T, Seifried A, Kaaks R, Rinaldi S, Wilkens L. Association of a common polymorphism in the human GH1 gene with colorectal neoplasia. J Natl Cancer Inst. 2002;94:454-60 pubmed
    ..01). The human T1663A GH1 gene polymorphism, which may confer lower levels of GH and IGF-I, appears to be associated with a decreased risk of colorectal cancer. ..
  2. request reprint
    Le Marchand L, Donlon T, Kolonel L, Henderson B, Wilkens L. Estrogen metabolism-related genes and breast cancer risk: the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev. 2005;14:1998-2003 pubmed
    ..They also provide support for an inverse association between CYP1A2*1F and breast cancer, which is consistent with the observation of lower circulating estrogen levels in premenopausal women with the CC genotype in a previous study. ..
  3. Le Marchand L, Wang H, Rinaldi S, Kaaks R, Vogt T, Yokochi L, et al. Associations of plasma C-peptide and IGFBP-1 levels with risk of colorectal adenoma in a multiethnic population. Cancer Epidemiol Biomarkers Prev. 2010;19:1471-7 pubmed publisher
    ..This study suggests that hyperinsulinemia and IGF hormones may act as etiologic factors in colorectal carcinogenesis, as early as during adenoma formation. ..
  4. Petridis C, Brook M, Shah V, Kohut K, Gorman P, Caneppele M, et al. Genetic predisposition to ductal carcinoma in situ of the breast. Breast Cancer Res. 2016;18:22 pubmed publisher
    ..0x10(-8). In conclusion, this study provides the strongest evidence to date of a shared genetic susceptibility for IDC and DCIS. Studies with larger numbers of DCIS are needed to determine if IDC or DCIS specific loci exist. ..
  5. Haiman C, Garcia R, Hsu C, Xia L, Ha H, Sheng X, et al. Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. BMC Cancer. 2009;9:43 pubmed publisher
    ....