- Epigenetic changes in pediatric solid tumors: promising new targetsElizabeth R Lawlor
Department of Pediatrics and Pathology, University of Michigan, Ann Arbor, Michigan, USA
Clin Cancer Res 18:2768-79. 2012..We also discuss how dramatic progress in our understanding of the fundamental mechanisms that contribute to epigenetic deregulation in cancer is providing novel avenues for targeted cancer therapy...
- CD133 expression in chemo-resistant Ewing sarcoma cellsXiaohua Jiang
Saban Research Institute, Childrens Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
BMC Cancer 10:116. 2010..Recently, the cell surface protein CD133 was identified as a putative marker of tumor-initiating cells in ESFT. We evaluated ESFT tumors and cell lines to determine if high levels of CD133 are associated with drug resistance...