B L Lasley

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Effects of soy consumption on gonadotropin secretion and acute pituitary responses to gonadotropin-releasing hormone in women
    Jill Nicholls
    Department of Nutrition, University of California Davis, CA 95616, USA
    J Nutr 132:708-14. 2002
  2. ncbi The relationship of circulating dehydroepiandrosterone, testosterone, and estradiol to stages of the menopausal transition and ethnicity
    Bill L Lasley
    Department of Population Health and Reproduction, University of California, Davis, California 95616, USA
    J Clin Endocrinol Metab 87:3760-7. 2002
  3. pmc Biomarkers for assessing human female reproductive health, an interdisciplinary approach
    B L Lasley
    Institute of Toxicology and Environmental Health, University of California, Davis 95616 8615, USA
    Environ Health Perspect 106:955-60. 1998
  4. pmc Adrenal androgens and the menopausal transition
    Bill L Lasley
    Center for Population Health and the Environment, University of California at Davis, CA 95616, USA
    Obstet Gynecol Clin North Am 38:467-75. 2011
  5. pmc Circulating dehydroepiandrosterone sulfate levels in women who underwent bilateral salpingo-oophorectomy during the menopausal transition
    Bill L Lasley
    Center for Health and the Environment, University of California at Davis, Davis, CA 95616, USA
    Menopause 18:494-8. 2011
  6. ncbi Estrogen and progesterone metabolites and follicle-stimulating hormone in the aged macaque female
    S E Shideler
    Institute of Toxicology and Environmental Health, University of California, Davis, California 95616, USA
    Biol Reprod 65:1718-25. 2001
  7. ncbi Molecular target of endocrine disruption in human luteinizing granulosa cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin: inhibition of estradiol secretion due to decreased 17alpha-hydroxylase/17,20-lyase cytochrome P450 expression
    F M Moran
    Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    Endocrinology 144:467-73. 2003
  8. ncbi Effect of dioxin on ovarian function in the cynomolgus macaque (M. fascicularis)
    F M Moran
    Institute of Toxicology and Environmental Health, University of California, Davis 95616, USA
    Reprod Toxicol 15:377-83. 2001
  9. ncbi Effects of two antiprogestins on early pregnancy in the long-tailed macaque (Macaca fascicularis)
    A F Tarantal
    California Regional Primate Research Center, University of California, Davis 95616, USA
    Contraception 54:107-15. 1996
  10. ncbi Effects of progesterone receptor blockers on human granulosa-luteal cell culture secretion of progesterone, estradiol, and relaxin
    C A VandeVoort
    California Regional Primate Research Center, Division of Reproductive Biology, Department of Ob Gyn and Institute of Toxicology and Environmental Health, University of California, Davis, California 95616, USA
    Biol Reprod 62:200-5. 2000

Detail Information

Publications50

  1. ncbi Effects of soy consumption on gonadotropin secretion and acute pituitary responses to gonadotropin-releasing hormone in women
    Jill Nicholls
    Department of Nutrition, University of California Davis, CA 95616, USA
    J Nutr 132:708-14. 2002
    ..In one premenopausal woman, enhanced LH secretion was observed after soy treatment, suggesting there may be subpopulations of women who are highly sensitive to isoflavones...
  2. ncbi The relationship of circulating dehydroepiandrosterone, testosterone, and estradiol to stages of the menopausal transition and ethnicity
    Bill L Lasley
    Department of Population Health and Reproduction, University of California, Davis, California 95616, USA
    J Clin Endocrinol Metab 87:3760-7. 2002
    ....
  3. pmc Biomarkers for assessing human female reproductive health, an interdisciplinary approach
    B L Lasley
    Institute of Toxicology and Environmental Health, University of California, Davis 95616 8615, USA
    Environ Health Perspect 106:955-60. 1998
    ..This effort requires specific skills of toxicologists, epidemiologists, physicians, biochemists, and physiologists...
  4. pmc Adrenal androgens and the menopausal transition
    Bill L Lasley
    Center for Population Health and the Environment, University of California at Davis, CA 95616, USA
    Obstet Gynecol Clin North Am 38:467-75. 2011
    ..Thus, adrenal steroid production may play a larger role in the occurrence of symptoms and the potential for healthier aging than previously recognized...
  5. pmc Circulating dehydroepiandrosterone sulfate levels in women who underwent bilateral salpingo-oophorectomy during the menopausal transition
    Bill L Lasley
    Center for Health and the Environment, University of California at Davis, Davis, CA 95616, USA
    Menopause 18:494-8. 2011
    ..The objective of this study was to determine the source of the rise in circulating DHEAS...
  6. ncbi Estrogen and progesterone metabolites and follicle-stimulating hormone in the aged macaque female
    S E Shideler
    Institute of Toxicology and Environmental Health, University of California, Davis, California 95616, USA
    Biol Reprod 65:1718-25. 2001
    ..e., females were less likely to return to normal ovarian cycles the following breeding season and more likely to exhibit permanent ovarian quiescence)...
  7. ncbi Molecular target of endocrine disruption in human luteinizing granulosa cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin: inhibition of estradiol secretion due to decreased 17alpha-hydroxylase/17,20-lyase cytochrome P450 expression
    F M Moran
    Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    Endocrinology 144:467-73. 2003
    ....
  8. ncbi Effect of dioxin on ovarian function in the cynomolgus macaque (M. fascicularis)
    F M Moran
    Institute of Toxicology and Environmental Health, University of California, Davis 95616, USA
    Reprod Toxicol 15:377-83. 2001
    ..These data demonstrate that a single exposure of 4 microg/kg BW TCDD leads to long-term adverse effects on ovarian function in primates...
  9. ncbi Effects of two antiprogestins on early pregnancy in the long-tailed macaque (Macaca fascicularis)
    A F Tarantal
    California Regional Primate Research Center, University of California, Davis 95616, USA
    Contraception 54:107-15. 1996
    ..m. and high dose oral dosing regimens, with little or no activity with the oral low dose; and (3) infants resulting from surviving pregnancies were not affected by early gestation exposure...
  10. ncbi Effects of progesterone receptor blockers on human granulosa-luteal cell culture secretion of progesterone, estradiol, and relaxin
    C A VandeVoort
    California Regional Primate Research Center, Division of Reproductive Biology, Department of Ob Gyn and Institute of Toxicology and Environmental Health, University of California, Davis, California 95616, USA
    Biol Reprod 62:200-5. 2000
    ..The data support the hypothesis that P(4) may be a required autocrine factor, not only for its own production but also for the maintenance of full endocrine function of the corpus luteum...
  11. ncbi Differences in hormonal characteristics of conceptive versus nonconceptive menstrual cycles
    H Li
    Institute of Toxicology and Environmental Health and Department of Obstetrics and Gynecology, University of California, Davis, USA
    Fertil Steril 75:549-53. 2001
    ..Urinary FSH measurements may be useful in predicting less fecund ovulatory cycles and may identify some types of reduced female fertility...
  12. ncbi Exposure to the dioxin 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces squamous metaplasia in the endocervix of cynomolgus macaques
    M A Scott
    Institute of Toxicology and Environmental Health, University of California, Davis 95616-8615, USA
    J Med Primatol 30:156-60. 2001
    ....
  13. ncbi Contribution of ovarian steroid production to urinary estrone conjugate concentrations in Macaca mulatta
    S E Shideler
    Center for Health and the Environment, University of California Davis, Davis, California 95616 8615, USA
    Am J Primatol 61:111-21. 2003
    ..The results indicate that the use of E1C measurements is clearly a suitable method for monitoring ovarian function in intact, cycling animals, but urinary E2 measurements are required to verify loss of follicular activity...
  14. ncbi Excretion and measurement of estradiol and progesterone metabolites in the feces and urine of female squirrel monkeys (Saimiri sciureus)
    E A Moorman
    Department of Psychology, University of California Davis, Davis, California 95616, USA
    Am J Primatol 57:79-90. 2002
    ..Examination of this profile confirmed that longitudinal fecal sampling and steroid hormone metabolite measurement in feces was not only feasible and practical, but accurately detected known reproductive events as well...
  15. ncbi Use of porcine zona pellucida (PZP) vaccine as a contraceptive agent in free-ranging tule elk (Cervus elaphus nannodes)
    S E Shideler
    Reprod Suppl 60:169-76. 2002
    ....
  16. pmc Effects of triclocarban on intact immature male rat: augmentation of androgen action
    Antoni J Duleba
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of California, Davis, CA 95817, USA
    Reprod Sci 18:119-27. 2011
    ..In conclusion, TCC significantly affects intact male reproductive organs and potentiates androgen effects in prostate cancer cells...
  17. ncbi Effect of estrogen and 2,3,7,8-tetrachlorodibenzo-rho-dioxin (TCDD) on plasma fatty acids of immature male chickens (Gallus domesticus)
    Beckye J Stanton
    Lasley Laboratory, Center for Health and the Environment, University of California, One Shields Ave, Davis, CA 95616, USA
    Comp Biochem Physiol C Toxicol Pharmacol 132:129-42. 2002
    ..Overall, TCDD treatment alone increased plasma lipids, possibly as a result of decreased clearance or utilization; whereas estrogen plus TCDD treatment antagonized estrogen-induced increases in 22:6n3 but did not cause hyperlipidemia...
  18. ncbi Metabolic and endocrine effects of a polyunsaturated fatty acid-rich diet in polycystic ovary syndrome
    Sidika E Kasim-Karakas
    Department of Internal Medicine, Division of Endocrinology and Metabolism, School of Medicine, University of California, Davis, California 95616, USA
    J Clin Endocrinol Metab 89:615-20. 2004
    ..Urinary pregnanediol 3-glucuronide increased from 18.6 +/- 2.2 to 31.0 +/- 5.7 micro g/mg creatinine (P = 0.038). In conclusion, increased dietary PUFA intake can exert significant metabolic and endocrine effects in women with PCOS...
  19. ncbi Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys
    Mari S Golub
    Department of Internal Medicine, California National Primate Research Center, University of California, Davis 95616, USA
    Toxicol Sci 74:103-13. 2003
    ..Long-term consequences of this disruption of pubertal development are being studied in this cohort of monkeys as adults...
  20. ncbi Effects of prune consumption on the ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone
    Sidika E Kasim-Karakas
    Department of Internal Medicine, Division of Endocrinology, Clinical Nutrition, and Vascular Medicine, University of California, Davis, CA 95817, USA
    Am J Clin Nutr 76:1422-7. 2002
    ..High fiber intake is also associated with decreased breast cancer risk...
  21. ncbi Sex steroid concentrations and localization of steroidogenic enzyme expression in free-ranging female northern fur seals (Callorhinus ursinus)
    Patience Browne
    Population, Health and Reproduction, University of California, Davis, 1114 Tupper Hall, 95616, USA
    Gen Comp Endocrinol 147:175-83. 2006
    ..These data suggest androgens may play a substantial regulatory role in the embryonic delay of northern fur seals...
  22. ncbi Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on chorionic gonadotropin secretion by human trophoblasts
    Jiangang Chen
    Center for Health and the Environment, School of Medicine, Tupper Hall, University of California, Davis, CA 95616, USA
    Reprod Toxicol 17:87-93. 2003
    ..These in vitro results support earlier in vivo studies in macaques suggesting that trophoblast is a target for TCCD and that TCDD-induced early pregnancy loss is accompanied by a decrease in the CG B/I ratio...
  23. ncbi Interaction of estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in immature male chickens (Gallus domesticus)
    B J Stanton
    Lasley Laboratory, Institute of Toxicology and Environmental Health, University of California, One Shields Ave, 95616, Davis, CA, USA
    Comp Biochem Physiol C Toxicol Pharmacol 129:35-47. 2001
    ..These data show that TCDD antagonized several effects of exogenous estrogen in male chickens, while estrogen enhanced TCDD toxicity in a tissue-specific manner...
  24. ncbi Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on fatty acid availability and neural tube formation in cynomolgus macaque, Macaca fascicularis
    F M Moran
    Center for Health and the Environment, University of California, Davis, California 95616, USA
    Birth Defects Res B Dev Reprod Toxicol 71:37-46. 2004
    ..Since neural tube development is dependent, in part, on n-3 and n-6 fatty acids, it is possible that the limitation of these essential fatty acids in plasma resulted in the observed detrimental effects on early brain development...
  25. pmc Detection of xenoestrogens in serum after immunoprecipitation of endogenous steroidal estrogens
    Kala Natarajan
    Center for Health and the Environment, University of California, Davis, California 95616 8615, USA
    Environ Health Perspect 110:791-5. 2002
    ..However, when steroidal estrogens were removed by immunoprecipitation, we detected the estrogenic activity of NP in the bioassay. Thus, this approach is appropriate for detecting exogenous, nonsteroidal estrogens in serum samples...
  26. ncbi Exogenous steroid substrate modifies the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estradiol production of human luteinized granulosa cells in vitro
    F M Moran
    Population Health and Reproduction, University of California, Davis, Davis, California 95616, USA
    Biol Reprod 68:244-51. 2003
    ..Thus, these data suggest that the most likely target for the TCDD-induced inhibition of estrogen synthesis by hLGC is the 17,20-lyase activity of the P450(c17) enzyme complex...
  27. ncbi Bayesian analysis of risk factors for anovulation
    Yan Liu
    Department of Epidemiology and Preventive Medicine, School of Medicine, University of California, Davis, CA 95616, USA
    Stat Med 23:1901-19. 2004
    ..Our results indicated that increasing physical activity was associated with a significantly increased risk of anovulation; and smokers had a potentially, but not statistically significant, increased occurrence of anovulation...
  28. ncbi Hormonal characteristics in the early luteal phase of conceptive and nonconceptive menstrual cycles
    Jiangang Chen
    Center for Health and the Environment, University of California, Davis, Davis, California, USA
    J Soc Gynecol Investig 10:27-31. 2003
    ..The differences in luteal phase hormones may reflect alterations in signaling in the hypothalamic-pituitary-ovarian axis that begin during the preovulatory period of nonconceptive cycles...
  29. ncbi Effect of porcine zonae pellucidae immunisation on ovarian follicular development and endocrine function in domestic ewes (Ovis aries)
    M A Stoops
    Department of Animal Science, University of California, Davis, CA 95616, USA
    Reprod Fertil Dev 18:667-76. 2006
    ..These data are the first generated in an ungulate species showing deleterious effects of pZP immunisation on folliculogenesis and oestrous cyclicity...
  30. ncbi Circulating bioactive androgens in midlife women
    Jiangang Chen
    Center for Health and the Environment, University of California, Davis, California 95616, USA
    J Clin Endocrinol Metab 91:4387-94. 2006
    ..It is important to characterize the biological activity of circulating androgenic steroid hormones during the menopausal transition because these appear to impact the metabolic and cardiovascular health risk factors of women...
  31. ncbi Urinary follicle-stimulating hormone peak as a biomarker for estimating the day of ovulation
    Hongxia Li
    Center for Health and the Environment, School of Medicine, University of California, Davis, Davis, California 95616 8739, USA
    Fertil Steril 77:961-6. 2002
    ..To evaluate urinary follicle-stimulating hormone (FSH) as a biomarker for the day of ovulation...
  32. ncbi Mild testicular hyperthermia induces profound transitional spermatogenic suppression through increased germ cell apoptosis in adult cynomolgus monkeys (Macaca fascicularis)
    Yan He Lue
    Department of Medicine, Harbor UCLA Medical Center and Research and Education Institute, University of California, Davis 90509, USA
    J Androl 23:799-805. 2002
    ..We conclude that, similar to rodents, mild testicular hyperthermia results in azoospermia and oligozoospermia in monkeys through increased germ cell apoptosis with minimal effect on the hormonal milieu...
  33. pmc Antiandrogenic properties of parabens and other phenolic containing small molecules in personal care products
    Jiangang Chen
    Center for Health and the Environment, University of California, Davis, CA 95616, USA
    Toxicol Appl Pharmacol 221:278-84. 2007
    ..The data presented in this report demonstrate that some widely used antimicrobial compounds have antiandrogenic properties and warrant further investigation to fully understand their potential impact on human reproductive health...
  34. pmc Triclocarban enhances testosterone action: a new type of endocrine disruptor?
    Jiangang Chen
    Center for Health and the Environment, University of California, Davis, California 95616, USA
    Endocrinology 149:1173-9. 2008
    ..The data presented here suggest that the bioactivity of endogenous hormones may be amplified by exposure to commercial personal care products containing sufficient levels of TCC...
  35. ncbi Hourly human chorionic gonadotropin secretion profiles during the peri-implantation period of successful pregnancies
    Pete N Lohstroh
    Center for Health and the Environment, University of California, Davis, California 95616 8615, USA
    Fertil Steril 87:1413-8. 2007
    ..To characterize the hourly profiles of hCG secretion in blood during conceptive cycles that ended in successful pregnancy...
  36. ncbi Secretion and excretion of human chorionic gonadotropin during early pregnancy
    Pete N Lohstroh
    Center for Health and the Environment, University of California Davis, Davis, CA 95616, USA
    Fertil Steril 83:1000-11. 2005
    ..To characterize the profiles of human chorionic gonadotropin (hCG) secretion in blood and its subsequent excretion in urine during conceptive cycles that ended in successful pregnancy and in spontaneous abortion...
  37. ncbi The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on chorionic gonadotrophin activity in pregnant macaques
    Jiangang Chen
    Center for Health and the Environment, University of California at Davis, One Shields Avenue, Davis, CA 95616 8739, USA
    Toxicology 186:21-31. 2003
    ..Because exposure of the conceptus to TCDD following differentiation of the trophoblast decreased the bioactivity of circulating mCG, we conclude that the action of TCDD in the placenta is directly on mCG synthesis...
  38. pmc Bone resorption is affected by follicular phase length in female rotating shift workers
    Pete N Lohstroh
    Center for Health and the Environment, University of California, Davis, California 95616, USA
    Environ Health Perspect 111:618-22. 2003
    ..In addition, these data indicate that there may be an association between accelerated bone resorption in menstrual cycles and changes of regularity in work schedule during the preceding LFPT...
  39. ncbi Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN)
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 127 Parran Hall 130 DeSoto St, Pittsburgh, PA 15261, USA
    Circulation 111:1242-9. 2005
    ..Recent clinical trials have shifted attention away from estrogens and toward androgens and sex hormone-binding globulin (SHBG) as potential mediators of increasing cardiovascular (CV) risk in women at midlife...
  40. ncbi Luteal phase deficiency in recreational runners: evidence for a hypometabolic state
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada M5S 2W6
    J Clin Endocrinol Metab 88:337-46. 2003
    ..These alterations may represent a metabolic adaptation to an intermittent short-term negative energy balance...
  41. ncbi Factors affecting menstrual cycle characteristics
    Yan Liu
    Center for Family Studies, Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Miami, Miami, FL 33136, USA
    Am J Epidemiol 160:131-40. 2004
    ..These results indicate that potentially modifiable risk factors, as well as immutable host factors, are associated with menstrual cycle characteristics that may in turn be related to subsequent disease risk...
  42. pmc Interactive effects of age and estrogen on cognition and pyramidal neurons in monkey prefrontal cortex
    Jiandong Hao
    Fishberg Department of Neuroscience and Kastor Neurobiology of Aging Laboratories, Mount Sinai School of Medicine, New York, NY 10029, USA
    Proc Natl Acad Sci U S A 104:11465-70. 2007
    ..The results also suggest that the cognitive benefit of E treatment in aged monkeys is mediated by enabling synaptic plasticity through a cyclical increase in small, highly plastic dendritic spines in the primate dlPFC...
  43. ncbi Reproductive hormones in the early menopausal transition: relationship to ethnicity, body size, and menopausal status
    John F Randolph
    Clinical Centers University of Michigan, Ann Arbor, Michigan 48109, USA
    J Clin Endocrinol Metab 88:1516-22. 2003
    ..All hormone concentrations were significantly correlated with body mass index. We conclude that serum sex steroid, FSH, and SHBG levels vary by ethnicity, but are highly confounded by ethnic disparities in body size...
  44. pmc Cigarette smoking and effects on hormone function in premenopausal women
    Gayle C Windham
    Division of Environmental and Occupational Disease Control, California Department of Health Services, Oakland, California, USA
    Environ Health Perspect 113:1285-90. 2005
    ..This endocrine disruption likely contributes to the reported associations of smoking with adverse reproductive outcomes, including menstrual dysfunction, infertility, and earlier menopause...
  45. ncbi A prospective study of serum DDT and progesterone and estrogen levels across the menstrual cycle in nulliparous women of reproductive age
    Melissa J Perry
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 164:1056-64. 2006
    ..03) in the luteal phase. These results support the potential for DDT to be associated with decrements in estrogen and progesterone levels at times during the menstrual cycle that are critical for ovulation and early pregnancy maintenance...
  46. ncbi Urinary estrogen and progesterone metabolite concentrations in menstrual cycles of fertile women with non-conception, early pregnancy loss or clinical pregnancy
    Scott A Venners
    Division of Epidemiology and Biostatistics, University of Illinois at Chicago, School of Public Health, Chicago, IL, USA
    Hum Reprod 21:2272-80. 2006
    ..Knowledge is limited of how estrogen and progesterone variability in fertile women are associated with achieving pregnancy...
  47. ncbi Urinary estrone conjugate and pregnanediol 3-glucuronide enzyme immunoassays for population research
    KATHLEEN A O'CONNOR
    Department of Anthropology and Center for Studies in Demography and Ecology, University of Washington, Seattle WA 98195, USA
    Clin Chem 49:1139-48. 2003
    ..We developed enzyme immunoassays for urinary pregnanediol 3-glucuronide (PDG) and estrone conjugates (E1Cs) that meet these criteria...
  48. ncbi Alcohol consumption and serum hormone levels during pregnancy
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, 263 Farmington Ave, Farmington, CT 06030, USA
    Alcohol 36:47-53. 2005
    ..Light alcohol intake during pregnancy is associated with lower maternal testosterone. The health implications are uncertain, but may include an increased breast density in the daughters of drinking mothers...
  49. ncbi Cellular expression and hormonal regulation of neuropilin-1 and -2 messenger ribonucleic Acid in the human and rhesus macaque endometrium
    Ariane Germeyer
    Department of Gynecology and Obstetrics, Stanford University School of Medicine, 300 Pasteur Drive, HH 333, Stanford, California 94305 5317, USA
    J Clin Endocrinol Metab 90:1783-90. 2005
    ..The findings extend our understanding of VEGF action in the primate endometrium...
  50. ncbi Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth
    Nihar R Nayak
    Department of Gynecology and Obstetrics, Stanford University, Stanford, CA 94305 5317, USA
    Mol Hum Reprod 11:791-9. 2005
    ..These data suggest, for the first time, that Ang-1 may play a key role in the P-dependent growth of the unique spiral arteries in the primate endometrium...