A W Lasek

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Downregulation of mu opioid receptor by RNA interference in the ventral tegmental area reduces ethanol consumption in mice
    A W Lasek
    The Ernest Gallo Clinic and Research Center, University of California at San Francisco, Emeryville, CA, USA
    Genes Brain Behav 6:728-35. 2007
  2. pmc Lmo4 in the nucleus accumbens regulates cocaine sensitivity
    A W Lasek
    The Ernest Gallo Clinic and Research Center, University of California at San Francisco, Emeryville, CA, USA
    Genes Brain Behav 9:817-24. 2010
  3. pmc Lmo genes regulate behavioral responses to ethanol in Drosophila melanogaster and the mouse
    Amy W Lasek
    Ernest Gallo Clinic and Research Center, University of California at San Francisco, California, USA
    Alcohol Clin Exp Res 35:1600-6. 2011
  4. pmc An evolutionary conserved role for anaplastic lymphoma kinase in behavioral responses to ethanol
    Amy W Lasek
    Department of Neurology, Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, California, United States of America
    PLoS ONE 6:e22636. 2011
  5. pmc Alk is a transcriptional target of LMO4 and ERα that promotes cocaine sensitization and reward
    Amy W Lasek
    The Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, California 94608, USA
    J Neurosci 31:14134-41. 2011
  6. ncbi Amygdala protein kinase C epsilon regulates corticotropin-releasing factor and anxiety-like behavior
    H M B Lesscher
    Department of Neurology, Ernest Gallo Clinic and Research Center, University of California at San Francisco, Emeryville, CA 94608, USA
    Genes Brain Behav 7:323-33. 2008

Detail Information

Publications6

  1. ncbi Downregulation of mu opioid receptor by RNA interference in the ventral tegmental area reduces ethanol consumption in mice
    A W Lasek
    The Ernest Gallo Clinic and Research Center, University of California at San Francisco, Emeryville, CA, USA
    Genes Brain Behav 6:728-35. 2007
    ..The RNAi combined with lentiviral delivery can be used successfully in brain to effect a sustained reduction in expression of specific genes for behavioral analysis...
  2. pmc Lmo4 in the nucleus accumbens regulates cocaine sensitivity
    A W Lasek
    The Ernest Gallo Clinic and Research Center, University of California at San Francisco, Emeryville, CA, USA
    Genes Brain Behav 9:817-24. 2010
    ..Thus, Lmo genes play conserved roles in regulating the behavioral effects of cocaine in invertebrate and mammalian models of drug addiction...
  3. pmc Lmo genes regulate behavioral responses to ethanol in Drosophila melanogaster and the mouse
    Amy W Lasek
    Ernest Gallo Clinic and Research Center, University of California at San Francisco, California, USA
    Alcohol Clin Exp Res 35:1600-6. 2011
    ..Herein, we examined whether dLmo influences the flies' sensitivity to ethanol's sedating effects. We also investigated whether 1 of the mammalian homologs of dLmo, Lmo3, is involved in behavioral responses to ethanol in mice...
  4. pmc An evolutionary conserved role for anaplastic lymphoma kinase in behavioral responses to ethanol
    Amy W Lasek
    Department of Neurology, Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, California, United States of America
    PLoS ONE 6:e22636. 2011
    ..These results suggest that Alk plays an evolutionary conserved role in ethanol-related behaviors. Moreover, ALK may be a novel candidate gene conferring risk for AUDs as well as a potential target for pharmacological intervention...
  5. pmc Alk is a transcriptional target of LMO4 and ERα that promotes cocaine sensitization and reward
    Amy W Lasek
    The Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, California 94608, USA
    J Neurosci 31:14134-41. 2011
    ..Our data suggest that estrogen regulation of Alk may be one mechanism responsible for sexually dimorphic responses to cocaine...
  6. ncbi Amygdala protein kinase C epsilon regulates corticotropin-releasing factor and anxiety-like behavior
    H M B Lesscher
    Department of Neurology, Ernest Gallo Clinic and Research Center, University of California at San Francisco, Emeryville, CA 94608, USA
    Genes Brain Behav 7:323-33. 2008
    ..These results are consistent with a novel mechanism of PKCepsilon control over anxiety-like behavior through regulation of CRF in the amygdala...