Research Topics
| Paul Sloan LarsonSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
A stroke of silence: tinnitus suppression following placement of a deep brain stimulation electrode with infarction in area LCPaul S Larson
Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
J Neurosurg 118:192-4. 2013..Clinicians treating patients with DBS may wish to include auditory phantom assessment as part of the neurological evaluation...
An optimized system for interventional magnetic resonance imaging-guided stereotactic surgery: preliminary evaluation of targeting accuracyPaul S Larson
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
Neurosurgery 70:95-103; discussion 103. 2012..A novel system (SurgiVision ClearPoint) consisting of an aiming device (SMARTFrame) and software has been developed specifically for interventional MRI, including deep brain stimulation...
Magnetic resonance imaging of implanted deep brain stimulators: experience in a large seriesPaul S Larson
Department of Neurological Surgery, University of California, San Francisco, CA 94143 0112, USA
Stereotact Funct Neurosurg 86:92-100. 2008..This series strongly suggests that the 0.1 W/kg recommendation for SAR may be unnecessarily low for the prevention of MRI-related adverse events...- Deep brain stimulation for psychiatric disordersPaul Sloan Larson
Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143 0112, USA
Neurotherapeutics 5:50-8. 2008..Current and future challenges for the use of DBS in psychiatric disorders are discussed, as well as a rationale for referring to this subspecialty as limbic disorders surgery based on the parallels with movement disorders surgery... - Implantation of deep brain stimulator electrodes using interventional MRIPhilip A Starr
Department of Neurosurgery, University of California, San Francisco, 533 Parnassus Avenue Box 0445, San Francisco, CA 94143, USA
Neurosurg Clin N Am 20:193-203. 2009..With further technical refinement, the interventional MRI method should improve the accuracy, safety, and speed of deep brain stimulator electrode placement... - Subthalamic nucleus deep brain stimulator placement using high-field interventional magnetic resonance imaging and a skull-mounted aiming device: technique and application accuracyPhilip A Starr
Department of Neurosurgery, University of California, San Francisco, California 94143, USA
J Neurosurg 112:479-90. 2010.... - Minimally invasive surgery for movement disordersPaul S Larson
Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143 0112
Neurosurg Clin N Am 21:691-8, vii. 2010..Finally, gene transfer eliminates the need for implanted hardware or batteries and simplifies postoperative care... - Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trialWilliam J Marks
Department of Neurology, University of California San Francisco, San Francisco, CA, USA
Lancet Neurol 9:1164-72. 2010..We aimed to assess the safety and efficacy of AAV2-neurturin in a double-blind, phase 2 randomised trial... - Human/nonhuman primate AC-PC ratio--considerations for translational brain measurementsMassimo S Fiandaca
Movement Disorders Laboratory, Department of Neurological Surgery, University of California San Francisco, 1855 Folsom Street, San Francisco, CA 94103, USA
J Neurosci Methods 196:124-30. 2011.... - Software requirements for interventional MR in restorative and functional neurosurgeryAlastair J Martin
Department of Radiology and Biomedical Imaging, University of California San Francisco, Box 0628, Room L 310, 505 Parnassus Avenue, San Francisco, CA 94143, USA
Neurosurg Clin N Am 20:179-86. 2009..An optimal software interface for iMRI requires fusion of many of the capabilities offered by these individual devices and further requires the development of tools to handle the integration and presentation of dynamically updated data... - Fluoroscopic, EMG-guided injection of botulinum toxin into the longus colli for the treatment of anterocollisGraham A Glass
Department of Neurology, UCSF Medical Center, San Francisco, CA 94143, USA
Parkinsonism Relat Disord 15:610-3. 2009..Deep cervical muscles such as the longus colli likely play an important role in neck flexion but are not routinely injected... - Interventional magnetic resonance guidance of deep brain stimulator implantation for Parkinson diseaseAlastair J Martin
Departments of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA
Top Magn Reson Imaging 19:213-21. 2009..Preliminary evaluation of clinical outcomes indicates comparable results to that achieved with conventional implantation methods, and the technique holds promise for substantially reducing operative durations... - Gene and cell delivery to the degenerated striatum: status of preclinical efforts in primate modelsR Mark Richardson
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
Neurosurgery 63:629-442; dicussion 642-4. 2008..The authors review data obtained from primate models that form the basis for ongoing clinical trials to consider how new preclinical models should be developed to answer questions that arise from experimental clinical data... - Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trialWilliam J Marks
Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 0138, USA
Lancet Neurol 7:400-8. 2008..The aim of this study was to assess the safety, tolerability, and potential efficacy of gene delivery of the neurotrophic factor neurturin... - Minimally invasive precision brain access using prospective stereotaxy and a trajectory guideAlastair J Martin
Department of Radiology, University of California, San Francisco, California 94143, USA
J Magn Reson Imaging 27:737-43. 2008..To evaluate the capabilities of MR-guided "prospective stereotaxy" methods for accessing brain structures for biopsy or electrode implantation... - Placement of deep brain stimulator electrodes using real-time high-field interventional magnetic resonance imagingAlastair J Martin
Department of Radiology, University of California, San Francisco, California 94143, USA
Magn Reson Med 54:1107-14. 2005..0 +/- 0.8 mm (range = 0.1-1.9 mm). All procedures were considered technical successes and there were no intraoperative complications; however, one patient did develop a postoperative infection... - Deep brain stimulator hardware-related infections: incidence and management in a large seriesKarl A Sillay
Department of Neurosurgery, University of California, San Francisco, California 94143 0445, USA
Neurosurgery 62:360-6; discussion 366-7. 2008..Device-related infection is a common complication of deep brain stimulator (DBS) implantation. We reviewed the incidence and management of early hardware-related infections in a large series... - Thalamic deep brain stimulation for essential tremor: relation of lead location to outcomeEfstathios Papavassiliou
Department of Neurosurgery, University of California, San Francisco, California 94143, USA
Neurosurgery 54:1120-29; discussion 1129-30. 2004..The incidence of true physiological tolerance to the antitremor effect of thalamic DBS (defined as poor tremor control in spite of lead location within 2 mm of the optimal site) was found to be 9%...