Research Topics
| A M LarsonSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
Hepatitis C in clinical practiceA M Larson
Department of Medicine, University of Washington, Seattle 98195 6174, USA
J Intern Med 249:111-20. 2001..By understanding the correct use of hepatitis C virus diagnostic testing and the risk and benefits of antiviral therapy, providers will be better equipped to screen and counsel their patients...- Integrating palliative care for liver transplant candidates: "too well for transplant, too sick for life"Anne M Larson
Department of Medicine, School of Medicine, University of Washington, Seattle 98195 6174, USA
JAMA 295:2168-76. 2006..In all of these circumstances, the health care team must combine elements of palliative care with life-sustaining therapy to maximize the patient's quality and quantity of life... - Liver disease in hereditary hemorrhagic telangiectasiaAnne M Larson
Department of Medicine, University of Washington, Seattle, 98195 6174, USA
J Clin Gastroenterol 36:149-58. 2003..Embolization of large arteriovenous malformations in the liver remains controversial; however, liver transplantation can successfully eradicate these complications... - Pilot study of the relationship between histologic progression and hepatic iron concentration in chronic hepatitis CAnne M Larson
Division of Gastroenterology, University of Washington, Seattle, WA 98195, USA
J Clin Gastroenterol 37:406-11. 2003..The interaction between progression of hepatitis C and iron deposition warrants further study... - Acetaminophen hepatotoxicityAnne M Larson
Division of Gastroenterology, Hepatology Section, University of Washington, 1959 NE Pacific Street, Box 356174, Seattle, WA 98195 6174, USA
Clin Liver Dis 11:525-48, vi. 2007..Liver transplantation can be lifesaving for those who develop acute liver failure... - Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective studyAnne M Larson
Department of Internal Medicine, Division of Gastroenterology, University of Washington Medical Center, Seattle, 98195, USA
Hepatology 42:1364-72. 2005..Susceptible patients have concomitant depression, chronic pain, alcohol or narcotic use, and/or take several preparations simultaneously. Education of patients, physicians, and pharmacies to limit high-risk use settings is recommended... - Endotheliitis in chronic viral hepatitis: a comparison with acute cellular rejection and non-alcoholic steatohepatitisMatthew M Yeh
Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195 6100, USA
Am J Surg Pathol 30:727-33. 2006.... - The expression of transforming growth factor-alpha in cirrhosis, dysplastic nodules, and hepatocellular carcinoma: an immunohistochemical study of 70 casesMatthew M Yeh
Department of Pathology, School of Medicine, University of Washington, Seattle, WA 98195 6100, USA
Am J Surg Pathol 31:681-9. 2007.... - Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunctionDeborah L Diamond
Department of Microbiology, University of Washington, Seattle, WA 98195 8070, USA
Hepatology 46:649-57. 2007..Our findings contribute to a generally emerging theme associating oxidative stress and hepatic mitochondrial dysfunction with HCV pathogenesis... 
Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failureWilliam M Lee
Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8887, USA
Gastroenterology 137:856-64, 864.e1. 2009..N-acetylcysteine (NAC), an antidote for acetaminophen poisoning, might benefit patients with non-acetaminophen-related acute liver failure...
False positive acetaminophen concentrations in patients with liver injuryJulie Polson
Department of Internal Medicine, University of Texas Southwestern Medical Center, 5959 Harry Hines Boulevard, Dallas, TX 75390, USA
Clin Chim Acta 391:24-30. 2008..However, recent case reports have suggested that acetaminophen concentrations may be falsely increased in the presence of hyperbilirubinemia...- Liver histology and alanine aminotransferase levels in children and adults with chronic hepatitis C infectionKaren F Murray
Division of Gastroenterology and Nutrition, Department of Pediatrics, Children's Hospital and Regional Medical Center, Seattle, WA 98195-6174, USA
J Pediatr Gastroenterol Nutr 41:634-8. 2005..CONCLUSIONS: With equal duration of infection, HCV-RNA level, and genotype, children have lower serum ALT levels and less severe liver disease than adults infected with HCV... - The protein kinase-interacting domain in the hepatitis C virus envelope glycoprotein-2 gene is highly conserved in genotype 1-infected patients treated with interferonS J Polyak
Virology Division, University of Washington, Seattle, WA 98104 2499, USA
J Infect Dis 182:397-404. 2000..The PePHD is highly conserved in HCV-1-infected IFN responders and nonresponders and does not appear to evolve in response to IFN therapy... - Fulminant hepatitis A virus infection in the United States: Incidence, prognosis, and outcomesRyan M Taylor
Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109-0362, USA
Hepatology 44:1589-97. 2006.... - Role of liver transplantation in acute liver failureIris W Liou
Division of Gastroenterology, University of Washington, Seattle, WA, USA
Semin Liver Dis 28:201-9. 2008..There are many ethical and psychosocial issues inherent to transplanting these sick patients due to the urgent nature of acute liver failure. Fortunately, the long-term survival and quality of life in these transplant recipients is good... - Elevated troponin I levels in acute liver failure: is myocardial injury an integral part of acute liver failure?Nimisha K Parekh
Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Hepatology 45:1489-95. 2007..Measurement of troponin I levels may be helpful in patients with acute liver failure, to detect unrecognized myocardial damage and as a marker of unfavorable outcome... - Temporary support for acute liver failurePankaj Rajvanshi
Division of Gastroenterology and Hepatology, University of Washington School of Medicine, Seattle, Washington 98195-6174, USA
J Clin Gastroenterol 35:335-44. 2002..We suggest an algorithm for management of patients with ALF that incorporates recent data... - Ischemic cholangiopathy following liver transplantation from donation after cardiac death donorsEdie Y Chan
Division of Transplantation, Department of Surgery, University of Washington, Seattle, WA 98195, USA
Liver Transpl 14:604-10. 2008..Careful donor selection may improve utilization of these grafts... - Cardiopulmonary consequences of transjugular intrahepatic portosystemic shunts: role of increased pulmonary artery pressureJonathan M Schwartz
Department of Medicine, Gastroenterology Division, University of Washington, Seattle, WA, USA
J Clin Gastroenterol 38:590-4. 2004..To determine whether increased pulmonary artery pressure (PAP) following transjugular intrahepatic portosystemic shunting (TIPSS) results in short-term mortality or cardiorespiratory complications... - Recipient and donor factors influence the incidence of graft-vs.-host disease in liver transplant patientsEdie Y Chan
Division of Transplantation, Department of Surgery, University of Washington, Seattle, WA 98195, USA
Liver Transpl 13:516-22. 2007..037). In conclusion, we have identified liver transplant patients with AIH or the combination of ALD, HCC, and glucose intolerance who receive a steatotic donor liver as being at high risk for developing GVHD... - Measurement of serum acetaminophen-protein adducts in patients with acute liver failureTimothy J Davern
University of California at San Francisco, San Francisco, California, USA corrected
Gastroenterology 130:687-94. 2006..Measurement of serum adducts might improve diagnostic accuracy in acute liver failure (ALF) patients... - Identifying risk for recurrent hepatocellular carcinoma after liver transplantation: implications for surveillance studies and new adjuvant therapiesEdie Y Chan
Division of Transplant Surgery, Department of General Surgery, Rush University Medical Center, Chicago, IL, USA
Liver Transpl 14:956-65. 2008..In conclusion, patients transplanted for HCC with a PCRS of < or =0 have a low risk of recurrence. Patients with a PCRS of 1 or 2 have a moderate risk of recurrence, and those with a PCRS of > or =3 have a high risk for recurrence... - Complications and use of intracranial pressure monitoring in patients with acute liver failure and severe encephalopathyJavier Vaquero
Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
Liver Transpl 11:1581-9. 2005..In view of the high 30-day survival rate after LT, future studies of the impact of intracranial hypertension should also focus on long-term neurological recovery from ALF... - Acute liver failureAnne M Larson
Dis Mon 54:457-85. 2008 - Screening for Wilson disease in acute liver failure: a comparison of currently available diagnostic testsJessica D Korman
Montefiore Medical Center, Bronx, NY, USA
Hepatology 48:1167-74. 2008..More readily available laboratory tests including alkaline phosphatase, bilirubin and serum aminotransferases by contrast provides the most rapid and accurate method for diagnosis of ALF due to WD...