Research Topics
| Christine LarongaSummaryAffiliation: University of South Florida Country: USA Publications
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Detail Information
Publications
Paget's disease in the era of sentinel lymph node biopsyChristine Laronga
Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute at the University of South Florida, 12902 Magnolia Drive, MCC BRPROG, Tampa, FL 33612 9497, USA
Am J Surg 192:481-3. 2006..quot;Breast cancer" management has evolved to include sentinel lymph node biopsy (SLNB). Our objective is to determine utilization of SLNB in the surgical algorithm of Paget's disease...- Quality of life with skin-sparing mastectomy: sensation in the nipple-areola complexChristine Laronga
Comprehensive Breast Program, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33620, USA
J Support Oncol 4:234-5. 2006 
Factors affecting lymph node yield in patients undergoing axillary node dissection for primary breast cancer: a single-institution reviewMarie Catherine Lee
Surgical Oncology, Comprehensive Breast Program, Moffitt Cancer Center, Tampa, FL, USA
Ann Surg Oncol 19:1818-24. 2012..A minimum of 10 level I/II axillary nodes is recommended for accurate breast cancer staging. The goal of this study was to assess the effect of neoadjuvant chemotherapy on lymph node yield at axillary lymph node dissection...- A mitotically active, cellular tumor stroma and/or inflammatory cells associated with tumor cells may contribute to intermediate or high Oncotype DX Recurrence Scores in low-grade invasive breast carcinomasGeza Acs
Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, FL 33612, USA
Mod Pathol 25:556-66. 2012..Careful assessment and correlation with histopathological features in such cases may help in determining the appropriate patient management... - Consequences of axillary ultrasound in patients with T2 or greater invasive breast cancersM Catherine Lee
Comprehensive Breast Program, Moffitt Cancer Center, Tampa, FL, USA
Ann Surg Oncol 18:72-7. 2011..Our hypothesis is that preoperative AUS significantly reduces sentinel node biopsy (SLNB) use in patients with invasive breast tumors >2 cm upon clinical examination... - Indications for sentinel lymph node biopsy in the setting of prophylactic mastectomyChristine Laronga
Don and Erika Wallace Comprehensive Breast Program, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr, MCC BRPROG, Tampa, FL 33612, USA
J Am Coll Surg 209:746-52; quiz 800-1. 2009..This single-institution study aims to identify patients who may benefit from sentinel node biopsy (SLNB) at the time of prophylactic mastectomy... - Ipsilateral nodal recurrence after axillary dissection for breast cancerNathaniel Walsh
University of South Florida, College of Medicine, Tampa, Florida, USA
J Surg Res 177:81-6. 2012..The objective of this study was to assess the incidence of regional nodal recurrence (RNR) after ALND performed for definitive operative treatment for primary breast cancer... - Male breast cancer: management and follow-up recommendationsJohn V Kiluk
Comprehensive Breast Program, Department of Women s Oncology, H Lee Moffitt Cancer Center, Tampa, Florida 33612, USA
Breast J 17:503-9. 2011..Increased awareness and a national registry for patients could help improve outcomes and tailor treatment recommendations to the male variant... - Phyllodes tumors: race-related differencesJose M Pimiento
Don and Erika Wallace Comprehensive Breast Program, Department of Women s Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
J Am Coll Surg 213:537-42. 2011..5% to 1% of all breast tumors. PT have unpredictable behavior, with recurrence rates as high as 40%. A dearth of information exists about racial differences; elucidation of these differences is the objective of this study... - Indications for axillary ultrasound use in breast cancer patientsJennifer E Joh
Comprehensive Breast Program, Department of Women s Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
Clin Breast Cancer 12:433-7. 2012..Axillary ultrasound has been adopted for preoperative planning in breast cancer. Our objective was to determine features predictive of abnormal AUS and/or positive axillary node needle biopsy (NBx)... - Pathologic tumor response of invasive lobular carcinoma to neo-adjuvant chemotherapyJennifer E Joh
Comprehensive Breast Program, Department of Women s Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
Breast J 18:569-74. 2012..Neo-adjuvant chemotherapy did not appear to have significant impact on the surgical treatment of patients with invasive lobular carcinoma... 
The effect of Oncotype DX recurrence score on treatment recommendations for patients with estrogen receptor-positive early stage breast cancer and correlation with estimation of recurrence risk by breast cancer specialistsJennifer E Joh
Department of Women s Oncology, Comprehensive Breast Program, H Lee Moffitt Cancer Center, Tampa, Florida 33612, USA
Oncologist 16:1520-6. 2011..This study has two primary endpoints: to evaluate the impact of Oncotype DX recurrence scores (RS) on chemotherapy recommendations and to compare the estimated recurrence risk predicted by breast oncology specialists to RS...- Differentiating fat necrosis from recurrent malignancy in fat-grafted breasts: an imaging classification system to guide managementRajiv P Parikh
Division of Plastic Surgery, Department of Surgery, University of South Florida, Tampa, Fla 33606, USA
Plast Reconstr Surg 130:761-72. 2012..The authors' objective was to develop standardized imaging classifications to distinguish benign from malignant lesions after fat grafting... - The extent of retraction clefts correlates with lymphatic vessel density and VEGF-C expression and predicts nodal metastasis and poor prognosis in early-stage breast carcinomaGeza Acs
Department of Anatomic Pathology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
Mod Pathol 25:163-77. 2012.... - HER2-positive male breast cancer with thyroid cancer: an institutional report and review of literaturePooja Bardhan
Department of Women s Oncology, Comprehensive Breast Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Ann Clin Lab Sci 42:135-9. 2012..Although this observation seems to be clinically prevalent, publications are sparse in clinical research areas linking thyroid cancer to breast cancer... - The role of the breast cancer surgeon in personalized cancer care: clinical utility of the 21-gene assayChristine Laronga
H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
Am J Surg 203:751-8. 2012.... - Prosthetic breast reconstruction after implant-sparing mastectomy in patients with submuscular implantsJessica Suber
Moffitt Cancer Center, University of South Florida, Department of Plastic and Reconstructive Surgery, Tampa, FL, USA
Ann Plast Surg 66:546-50. 2011..Implant-sparing mastectomy with delayed exchange provides an alternative to tissue expander placement and associated morbidities. This technique provides excellent results with minimal complications for this patient population... - Feasibility of sentinel lymph node biopsy through an inframammary incision for a nipple-sparing mastectomyJohn V Kiluk
Breast Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Ann Surg Oncol 15:3402-6. 2008..The objective of this study is to determine the technical feasibility of performing SLN through an IM incision without making an axillary counterincision... - The changing face of mastectomy: an oncologic and cosmetic perspectiveChristine Laronga
Comprehensive Breast Program, Department of Women s Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Cancer Control 19:286-94. 2012..Among the recent advances in technique is the nipple-sparing mastectomy, which reflects the emerging focus on cosmetic outcomes... - Cognitive functioning after cancer treatment: a 3-year longitudinal comparison of breast cancer survivors treated with chemotherapy or radiation and noncancer controlsKristin M Phillips
Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida 33612, USA
Cancer 118:1925-32. 2012..Changes in cognitive functioning over time were compared in breast cancer survivors treated with chemotherapy plus radiotherapy, breast cancer survivors treated with radiotherapy only, and women with no history of cancer... - Serum insulin-like growth factor (IGF)-1 and IGF binding protein-3 in relation to breast cancer among Hispanic and white, non-Hispanic women in the US SouthwestDana E Rollison
Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Magnolia Drive, Tampa, FL 33612, USA
Breast Cancer Res Treat 121:661-9. 2010..45-7.60; Q4 vs. Q1 for Hispanics: OR = 2.15, 95% CI = 0.76-6.04). In conclusion, the association between IGF-1 and breast cancer differed by ethnicity, while no ethnic differences were observed in IGFBP-3-associated breast cancer... - Gene expression profiling in breast cancerKiran Turaga
Department of Women s Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Cancer Control 17:177-82. 2010..This heterogeneity has spawned an era of molecular assays striving to classify and thus predict outcome, thereby guiding the future in targeted personalized treatment strategies... - Recall of and reactions to a surgeon referral letter for BRCA genetic counseling among high-risk breast cancer patientsSusan T Vadaparampil
Moffitt Cancer Center, Tampa, FL, USA
Ann Surg Oncol 16:1973-81. 2009..This qualitative study examined the impact of a surgeon referral letter on recently diagnosed breast cancer patients' uptake of BRCA GC... - Population-based case-control study of diabetes and breast cancer risk in Hispanic and non-Hispanic White women living in US southwestern statesDana E Rollison
Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Am J Epidemiol 167:447-56. 2008..54, 95% confidence interval: 0.37, 0.79). In this study, diabetes was not associated with breast cancer overall, although the inverse association with gestational diabetes warrants further investigation... - The presence of micropapillary features and retraction artifact in core needle biopsy material predicts lymph node metastasis in breast carcinomaGeza Acs
Anatomic Pathology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Am J Surg Pathol 33:202-10. 2009.... - SELDI-TOF serum profiling for prognostic and diagnostic classification of breast cancersChristine Laronga
Department of Surgery, Eastern Virginia Medical School, Norfolk, Virginia and the Virginia Prostate Center, Norfolk, VA, USA
Dis Markers 19:229-38. 2003..These initial results indicate the utility of protein profiling approaches for developing new diagnostic and prognostic assays for breast cancers... - Micrometastasis in the sentinel lymph node of breast cancer does not mandate completion axillary dissectionKeith Fournier
Departments of Surgery, Eastern Virginia Medical School, Norfolk, VA, USA
Ann Surg 239:859-63; discussion 863-5. 2004..This suggests that a CAD may be omitted in patients with micrometastatic disease... - Obesity and lymphatic mapping with sentinel lymph node biopsy in breast cancerMarybeth Hughes
Department of Surgery, Eastern Virginia Medical School, 825 Fairfax Ave, Suite 610, Norfolk, VA 23507, USA
Am J Surg 187:52-7. 2004..7783 and P = 0.9290, respectively) among the three groups. CONCLUSIONS: Obesity has no significant effect on sentinel node identification rate or false negative rate... - Effects of sentinel lymph node biopsy on surgical residency trainingSusanna Shin
Department of Surgery, Eastern Virginia Medical School, Norfolk, USA
Am Surg 72:791-5; discussion 795-7. 2006..As fewer AND are performed than our attendings cite to feel comfortable, future residents may not be competent to perform or teach AND... - Breast cancer risk reductionTherese B Bevers
National Comprehensive Cancer Network
J Natl Compr Canc Netw 5:676-701. 2007 - A novel approach toward development of a rapid blood test for breast cancerAntonia Vlahou
Department of Microbiology, and Virginia Prostate Center, Eastern Virginia Medical School, Norfolk, VA 23507, USA
Clin Breast Cancer 4:203-9. 2003..The combination of SELDI ProteinChip mass spectrometry and a classification- and regression-tree algorithm has the potential to use serum protein expression profiles for detection and diagnosis of breast cancer... - Serum biomarkers to differentiate benign and malignant mammographic lesionsSusanna Shin
Department of Surgery, Eastern Virginia Medical School, Norfolk, VA 23507, USA
J Am Coll Surg 204:1065-71; discussion 1071-3. 2007..Our objective was to determine if serum protein-expression profiles could be used to differentiate between benign and malignant mammographic lesions... - Lymphedema of the arm and breast in irradiated breast cancer patients: risks in an era of dramatically changing axillary surgeryThomas E Goffman
Department of Radiation Oncology, Eastern Virginia Medical School, Norfolk 23507, USA
Breast J 10:405-11. 2004..For breast edema, disruption of draining lymphatics by surgery and radiation with boost to the upper outer quadrant increased risk, especially for the obese. Fortunately both breast and arm edema benefited from manual lymphatic drainage... - Proteomic approach to breast cancerChristine Laronga
Department of Surgery, Eastern Virginia Medical School, Norfolk, Virginia, USA
Cancer Control 14:360-8. 2007..Proteomics is a rapidly developing field that can explore the heterogeneity of breast cancer and supplement the wealth of information gained from genomics... - Pharmacoproteomic analysis of prechemotherapy and postchemotherapy plasma samples from patients receiving neoadjuvant or adjuvant chemotherapy for breast carcinomaLajos Pusztai
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
Cancer 100:1814-22. 2004..The authors also compared the plasma profiles of patients with cancer with the plasma profiles of healthy women to identify breast carcinoma-associated protein markers... - Shielding of the contralateral breast during tangential irradiationThomas E Goffman
Department of Radiation Oncology, Eastern Virginia Medical School, Norfolk, Virginia, USA
Am J Clin Oncol 27:436-9. 2004..For younger patients in whom radiation exposure is of considerable concern, a simple shield of 2 mm lead thickness proved practical and effective... - Impact of race on breast cancer in lower socioeconomic status womenNell Maloney
Department of Surgery, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA
Breast J 12:58-62. 2006..026). Breast cancer in African American women traditionally presents at a more advanced stage and with poor prognostic features. However, when matched for lower socioeconomic status, racial disparities essentially disappear... - Follow-up recommendations for benign breast biopsiesSusanna Shin
Department of Surgery, Eastern Virginia Medical School, Norfolk, VA 23507, USA
Breast J 12:413-7. 2006..This should include imaging (mammography or ultrasound) and a clinical breast examination 6 months, 1 year, and 2 years after a benign breast biopsy... - DNA damage-induced protein 14-3-3 sigma inhibits protein kinase B/Akt activation and suppresses Akt-activated cancerHuiling Yang
Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer Res 66:3096-105. 2006..These data provide an insight into Akt regulation and rational cancer gene therapy by identifying 14-3-3 sigma as a molecular regulator of Akt and as a potential anticancer agent for Akt-activated cancers... - Surfaced-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) differentiation of serum protein profiles of BRCA-1 and sporadic breast cancerStephen Becker
Department of Surgery, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 610, Norfolk, VA 23507, USA
Ann Surg Oncol 11:907-14. 2004..Follow-up studies with larger numbers and longer follow-up are required to validate these findings but may allow more timely prophylactic or therapeutic strategies...