Research Topics
| Carolyn A LarabellSummaryAffiliation: University of California Country: USA Publications
| Collaborators
|
Detail Information
Publications
X-ray tomography generates 3-D reconstructions of the yeast, saccharomyces cerevisiae, at 60-nm resolutionCarolyn A Larabell
Department of Anatomy, University of California, San Francisco California 94143, USA
Mol Biol Cell 15:957-62. 2004..In this video essay, we show examples of 3-D tomographic reconstructions of whole yeast and demonstrate the power of this technology to obtain quantifiable information from whole, hydrated cells...- Quantitative 3-D imaging of eukaryotic cells using soft X-ray tomographyDilworth Y Parkinson
Physical Biosciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, MS 6 2100, Berkeley, CA 94720, USA
J Struct Biol 162:380-6. 2008.... 
A PKC wave follows the calcium wave after activation of Xenopus eggsCarolyn A Larabell
Department of AnatomyUniversity of California, San FranciscoSan Francisco, CA 94143, USA
Differentiation 72:41-7. 2004..This is the first example of a PKC wave in a vertebrate egg and supports the IICR model of wave propagation...- Measuring cell motility using quantum dot probesWeiwei Gu
Department of Anatomy, University of California, San Francisco, CA, USA
Methods Mol Biol 374:125-31. 2007..Because the technique only relies on fluorescence detection, requires no significant data processing, and is used with live cells, it is both rapid and straightforward... - Quantitative analysis of yeast internal architecture using soft X-ray tomographyMaho Uchida
Department of Anatomy, University of California at San Francisco, CA 94143 2722, USA
Yeast 28:227-36. 2011..cerevisiae. This comparison revealed that volumetric ratios were invariant, irrespective of yeast strain, ploidy or morphology, leading to the conclusion these volumetric ratios are common in all yeasts... - Visualizing and quantifying cell phenotype using soft X-ray tomographyGerry McDermott
Department of Anatomy, University of California, San Francisco, CA, USA
Bioessays 34:320-7. 2012..This combination of data types allows sophisticated analyses to be carried out on the impact of environmental and/or genetic factors on cell phenotypes... - Imaging cellular architecture with X-raysCarolyn A Larabell
Department of Anatomy, University of California at San Francisco, 1550 4th Street, San Francisco, CA 94158, USA
Curr Opin Struct Biol 20:623-31. 2010..These methods are at a much earlier stage of development but, as they eliminate the need for X-ray optics, have the capacity to provide substantially better spatial resolution than zone plate-based methods... - Visualizing cell architecture and molecular location using soft x-ray tomography and correlated cryo-light microscopyGerry McDermott
Department of Anatomy, University of California, San Francisco, 94158, USA
Annu Rev Phys Chem 63:225-39. 2012.... - Soft X-ray tomography and cryogenic light microscopy: the cool combination in cellular imagingGerry McDermott
Department of Anatomy, University of California San Francisco, CA 94143, USA
Trends Cell Biol 19:587-95. 2009..This multi-modal approach allows labelled molecules to be localized in the context of a high-resolution 3-D tomographic reconstruction of the cell... - X-ray tomography of Schizosaccharomyces pombeWeiwei Gu
Department of Anatomy University of California, 513 Parnassus San Francisco, CA 94143, USA
Differentiation 75:529-35. 2007.... 
Nuclear aggregation of olfactory receptor genes governs their monogenic expressionE Josephine Clowney
Program in Biomedical Sciences, University of California, San Francisco, San Francisco, CA 94158, USA
Cell 151:724-37. 2012..Our observations propose spatial sequestering of heterochromatinized OR family members as a basis of monogenic and monoallelic gene expression...- Quantum-dot-based cell motility assayWeiwei Gu
Department of Anatomy, University of California, San Francisco, CA 94143, USA
Sci STKE 2005:pl5. 2005.... - Soft X-ray tomography of phenotypic switching and the cellular response to antifungal peptoids in Candida albicansMaho Uchida
Department of Anatomy, School of Medicine, University of California, San Francisco, CA, USA
Proc Natl Acad Sci U S A 106:19375-80. 2009..In particular, peptoid treatment was seen to cause the inclusion of lipidic bodies into the nucleus... - The maternally localized RNA fatvg is required for cortical rotation and germ cell formationAgnes P Chan
Department of Molecular Genetics, University of Texas, M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
Mech Dev 124:350-63. 2007..These results point to a common fundamental mechanism that is regulated by fatvg through which germ cell determinants and dorsalizing factors segregate during early development... - Disruption of the dynamic sub-cellular localization of the Xenopus tumorhead protein causes embryonic lethality at the early gastrula transitionEdwin E Traverso
Department of Molecular Genetics, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
Differentiation 75:947-56. 2007..Our data also suggest that TH plays a role outside the nucleus when it is present at the cell periphery... - X-ray tomography of whole cellsMark A Le Gros
Physical Biosciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, MS 6-2100, Berkeley, CA 94720, USA
Curr Opin Struct Biol 15:593-600. 2005..The new generation of X-ray optics will extend this resolution limit to 15 nm or better. The development of X-ray tomography of whole cells generates opportunities to study cells, and cellular processes, in a completely new way... - Imaging whole Escherichia coli bacteria by using single-particle x-ray diffractionJianwei Miao
Stanford Synchrotron Radiation Laboratory, Stanford Linear Accelerator Center, Stanford University, CA 94309 0210, USA
Proc Natl Acad Sci U S A 100:110-2. 2003....