D D Langleben

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Brain activity during simulated deception: an event-related functional magnetic resonance study
    D D Langleben
    Department of Psychiatry, Treatment Research Center, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 15:727-32. 2002
  2. ncbi Emerging neurotechnologies for lie-detection: promises and perils
    Paul Root Wolpe
    University of Pennsylvania, USA
    Am J Bioeth 5:39-49. 2005
  3. ncbi Interhemispheric asymmetry of regional cerebral blood flow in prepubescent boys with attention deficit hyperactivity disorder
    D D Langleben
    The Department of Psychiatry, Treatment Research Center, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Nucl Med Commun 22:1333-40. 2001
  4. ncbi Telling truth from lie in individual subjects with fast event-related fMRI
    Daniel D Langleben
    University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Hum Brain Mapp 26:262-72. 2005
  5. ncbi Effect of methylphenidate on Stroop Color-Word task performance in children with attention deficit hyperactivity disorder
    Daniel D Langleben
    Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Psychiatry Res 141:315-20. 2006
  6. ncbi Commentary: the future of forensic functional brain imaging
    Daniel D Langleben
    Treatment Research Center, Department of Psychiatry, University of Pennsylvania School of Medicine, 3900, Chestnut Street, Philadelphia, PA 19104, USA
    J Am Acad Psychiatry Law 36:502-4. 2008
  7. ncbi Effects of methylphenidate discontinuation on cerebral blood flow in prepubescent boys with attention deficit hyperactivity disorder
    Daniel D Langleben
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Nucl Med 43:1624-9. 2002
  8. ncbi Towards clinical trials of lie detection with fMRI
    J G Hakun
    University of Pennsylvania, Philadelphia, Pennsylvania 19104 6178, USA
    Soc Neurosci 4:518-27. 2009
  9. ncbi fMRI investigation of the cognitive structure of the Concealed Information Test
    J G Hakun
    Department of Psychiatry, University of Pennsylvania and the Veterans Administration Medical Center, Philadelphia, PA, USA
    Neurocase 14:59-67. 2008
  10. ncbi Low prefrontal perfusion linked to depression symptoms in methadone-maintained opiate-dependent patients
    Jesse J Suh
    Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, United States
    Drug Alcohol Depend 99:11-7. 2009

Research Grants

  1. Functional neuromaging of cue-induced heroin craving
    Daniel Langleben; Fiscal Year: 2007
  2. Functional MRI of anti-tobacco public service announcements
    Daniel Langleben; Fiscal Year: 2007

Detail Information

Publications17

  1. ncbi Brain activity during simulated deception: an event-related functional magnetic resonance study
    D D Langleben
    Department of Psychiatry, Treatment Research Center, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 15:727-32. 2002
    ....
  2. ncbi Emerging neurotechnologies for lie-detection: promises and perils
    Paul Root Wolpe
    University of Pennsylvania, USA
    Am J Bioeth 5:39-49. 2005
    ..Premature application of these technologies outside of research settings should be resisted, and the social conversation about the appropriate parameters of its civil, forensic, and security use should begin...
  3. ncbi Interhemispheric asymmetry of regional cerebral blood flow in prepubescent boys with attention deficit hyperactivity disorder
    D D Langleben
    The Department of Psychiatry, Treatment Research Center, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Nucl Med Commun 22:1333-40. 2001
    ..Reversal of functional prefrontal asymmetry in boys with severe motor hyperactivity supports the hypothesis of right prefrontal cortex dysfunction in ADHD...
  4. ncbi Telling truth from lie in individual subjects with fast event-related fMRI
    Daniel D Langleben
    University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Hum Brain Mapp 26:262-72. 2005
    ..Salience of the task cues is a potential confounding factor in the fMRI pattern attributed to deception in forced choice deception paradigms...
  5. ncbi Effect of methylphenidate on Stroop Color-Word task performance in children with attention deficit hyperactivity disorder
    Daniel D Langleben
    Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Psychiatry Res 141:315-20. 2006
    ....
  6. ncbi Commentary: the future of forensic functional brain imaging
    Daniel D Langleben
    Treatment Research Center, Department of Psychiatry, University of Pennsylvania School of Medicine, 3900, Chestnut Street, Philadelphia, PA 19104, USA
    J Am Acad Psychiatry Law 36:502-4. 2008
    ..We propose that further progress in brain imaging research may foster the emergence of a new discipline of forensic MRI...
  7. ncbi Effects of methylphenidate discontinuation on cerebral blood flow in prepubescent boys with attention deficit hyperactivity disorder
    Daniel D Langleben
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Nucl Med 43:1624-9. 2002
    ..To address this issue, we assessed the effects of discontinuation of chronic MPH treatment on regional cerebral blood flow (rCBF) in ADHD patients...
  8. ncbi Towards clinical trials of lie detection with fMRI
    J G Hakun
    University of Pennsylvania, Philadelphia, Pennsylvania 19104 6178, USA
    Soc Neurosci 4:518-27. 2009
    ..Our experiment suggests an approach to a naturalistic scenario and the research questions that need to be answered in order to set the stage for prospective clinical trials of fMRI-based lie detection...
  9. ncbi fMRI investigation of the cognitive structure of the Concealed Information Test
    J G Hakun
    Department of Psychiatry, University of Pennsylvania and the Veterans Administration Medical Center, Philadelphia, PA, USA
    Neurocase 14:59-67. 2008
    ..This study presents a systematic strategy for testing the cognitive basis of deception models, and a qualitative approach to single-subject truth-verification fMRI tests...
  10. ncbi Low prefrontal perfusion linked to depression symptoms in methadone-maintained opiate-dependent patients
    Jesse J Suh
    Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, United States
    Drug Alcohol Depend 99:11-7. 2009
    ..In this study, we examined the link between resting rCBF in the PFC and current depressive symptoms in methadone-maintained opiate-dependent (MM) patients with or without major depression...
  11. ncbi Acute effect of methadone maintenance dose on brain FMRI response to heroin-related cues
    Daniel D Langleben
    Department of Psychiatry, University of Pennsylvania, Treatment Research Center, Philadelphia, PA 19104, USA
    Am J Psychiatry 165:390-4. 2008
    ..The authors sought to identify the functional neuroanatomy of the brain response to visual heroin-related stimuli in methadone maintenance patients...
  12. ncbi Classifying spatial patterns of brain activity with machine learning methods: application to lie detection
    C Davatzikos
    Department of Radiology, University of Pennsylvania, 3600 Market Street, Suite 380, Philadelphia, PA 19104, USA
    Neuroimage 28:663-8. 2005
    ....
  13. ncbi Reduced prefrontal and temporal processing and recall of high "sensation value" ads
    Daniel D Langleben
    Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Neuroimage 46:219-25. 2009
    ..These findings demonstrate the potential of using neuroimaging in the design and evaluation of mass media public health communications...
  14. ncbi Emerging neurotechnologies for lie-detection: promises and perils
    Paul Root Wolpe
    University of Pennsylvania, USA
    Am J Bioeth 10:40-8. 2010
    ..Premature application of these technologies outside of research settings should be resisted, and the social conversation about the appropriate parameters of its civil, forensic, and security use should begin...
  15. ncbi Neural substrates for functionally discriminating self-face from personally familiar faces
    Steven M Platek
    Department of Psychology, Drexel University, and Department of Psychiatry, Brain Behavior Laboratory, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Hum Brain Mapp 27:91-8. 2006
    ....
  16. ncbi Effects of pharmacological doses of 2-deoxyglucose on plasma catecholamines and glucose levels in patients with schizophrenia
    Igor Elman
    Department of Psychiatry, McLean Hospital and Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
    Psychopharmacology (Berl) 176:369-75. 2004
    ..Several lines of evidence suggest that the pathophysiology of schizophrenia may be associated with altered noradrenergic and glucoregulatory function...
  17. ncbi The acute effect of methylphenidate on cerebral blood flow in boys with attention-deficit/hyperactivity disorder
    Claudia M Szobot
    Department of Psychiatry, Federal University of Rio Grande do Sul, Brazil
    Eur J Nucl Med Mol Imaging 30:423-6. 2003
    ..05, corrected for multiple comparisons). Our findings suggest that the posterior attentional system, which includes the parietal cortex, may have a role in the mediation of the therapeutic effects of MPH in ADHD...

Research Grants3

  1. Functional neuromaging of cue-induced heroin craving
    Daniel Langleben; Fiscal Year: 2007
    ..Implementation of this training and research plan will help the candidate to become an independent investigator in the neuropsychiatry of addiction. ..
  2. Functional MRI of anti-tobacco public service announcements
    Daniel Langleben; Fiscal Year: 2007
    ....