Research Topics

Kenneth L Lange


Affiliation: University of California
Country: USA


  1. Zhou H, Sinsheimer J, Bates D, Chu B, German C, Ji S, et al. OPENMENDEL: a cooperative programming project for statistical genetics. Hum Genet. 2019;: pubmed publisher
    ..This article reviews and makes recommendations to the genetic epidemiology community in the context of the OPENMENDEL project. ..
  2. Landeros A, Stutz T, Keys K, Alekseyenko A, Sinsheimer J, Lange K, et al. BioSimulator.jl: Stochastic simulation in Julia. Comput Methods Programs Biomed. 2018;167:23-35 pubmed publisher
    ..The user-friendly nature of BioSimulator.jl encourages the use of stochastic simulation, minimizes tedious programming efforts, and reduces errors during model specification. ..
  3. Chi E, Lange K. A Look at the Generalized Heron Problem through the Lens of Majorization-Minimization. Am Math Mon. 2014;121:95-108 pubmed
  4. Lange K, Chi E, Zhou H. A Brief Survey of Modern Optimization for Statisticians. Int Stat Rev. 2014;82:46-70 pubmed
    ..Algorithm derivation is also emphasized, and theory is downplayed, particularly the abstractions of the convex calculus. Thus, our survey should be useful and accessible to a broad audience. ..
  5. Chi E, Zhou H, Lange K. Distance majorization and its applications. Math Program. 2014;146:409-436 pubmed
    ..The performance of our distance majorization algorithms is illustrated in several applications. ..
  6. Lange K, Papp J, Sinsheimer J, Sripracha R, Zhou H, Sobel E. Mendel: the Swiss army knife of genetic analysis programs. Bioinformatics. 2013;29:1568-70 pubmed publisher
    ..Compared with earlier versions, Mendel is faster and easier to use and has a wider range of applications. Supported platforms include Linux, MacOS and Windows. Free from ..
  7. Alexander D, Lange K. Enhancements to the ADMIXTURE algorithm for individual ancestry estimation. BMC Bioinformatics. 2011;12:246 pubmed publisher
    ..Finally, by exploiting multiple processors, large datasets can be analyzed even more rapidly. The enhancements we have described make ADMIXTURE a more accurate, efficient, and versatile tool for ancestry estimation. ..