Frédéric Landmann

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Efficient in vitro RNA interference and immunofluorescence-based phenotype analysis in a human parasitic nematode, Brugia malayi
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95604, USA
    Parasit Vectors 5:16. 2012
  2. ncbi Asymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissues
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
    PLoS Negl Trop Dis 4:e758. 2010
  3. ncbi The genetics and cell biology of Wolbachia-host interactions
    Laura R Serbus
    Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064, USA
    Annu Rev Genet 42:683-707. 2008
  4. ncbi Anti-filarial activity of antibiotic therapy is due to extensive apoptosis after Wolbachia depletion from filarial nematodes
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, Sinsheimer Labs, University of California, Santa Cruz, California, United States of America
    PLoS Pathog 7:e1002351. 2011
  5. ncbi Both asymmetric mitotic segregation and cell-to-cell invasion are required for stable germline transmission of Wolbachia in filarial nematodes
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, Sinsheimer Laboratories, University of California, Santa Cruz, CA 95064, USA
    Biol Open 1:536-47. 2012
  6. ncbi A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia
    Laura R Serbus
    Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California, USA
    PLoS Pathog 8:e1002922. 2012
  7. ncbi Wolbachia-mediated cytoplasmic incompatibility is associated with impaired histone deposition in the male pronucleus
    Frédéric Landmann
    Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, USA
    PLoS Pathog 5:e1000343. 2009

Detail Information

Publications7

  1. ncbi Efficient in vitro RNA interference and immunofluorescence-based phenotype analysis in a human parasitic nematode, Brugia malayi
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95604, USA
    Parasit Vectors 5:16. 2012
    ..However, RNAi techniques have not translated efficiently to animal parasitic nematodes that afflict humans, livestock and companion animals across the globe, creating a dependency on data tentatively inferred from C. elegans...
  2. ncbi Asymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissues
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
    PLoS Negl Trop Dis 4:e758. 2010
    ..Wolbachia rely on fusion of hypodermal cells to populate adult chords. Finally, we detect Wolbachia in the secretory canal lumen suggesting living worms may release bacteria and/or their products into their host...
  3. ncbi The genetics and cell biology of Wolbachia-host interactions
    Laura R Serbus
    Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064, USA
    Annu Rev Genet 42:683-707. 2008
    ..The areas of discussion include Wolbachia transmission in oogenesis, Wolbachia distribution in spermatogenesis, induction and rescue of the CI phenotype, Wolbachia genomics, and Wolbachia-membrane interactions...
  4. ncbi Anti-filarial activity of antibiotic therapy is due to extensive apoptosis after Wolbachia depletion from filarial nematodes
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, Sinsheimer Labs, University of California, Santa Cruz, California, United States of America
    PLoS Pathog 7:e1002351. 2011
    ....
  5. ncbi Both asymmetric mitotic segregation and cell-to-cell invasion are required for stable germline transmission of Wolbachia in filarial nematodes
    Frédéric Landmann
    Department of Molecular, Cell and Developmental Biology, Sinsheimer Laboratories, University of California, Santa Cruz, CA 95064, USA
    Biol Open 1:536-47. 2012
    ..The utilization of cell-to-cell invasion for germline colonization may indicate an ancestral mode of horizontal transfer that preceded the acquisition of the mutualism...
  6. ncbi A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia
    Laura R Serbus
    Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California, USA
    PLoS Pathog 8:e1002922. 2012
    ..This suggests that the efficacy of Albendazole in treating filarial nematode-based diseases is attributable to dual targeting of nematode microtubules and their Wolbachia endosymbionts...
  7. ncbi Wolbachia-mediated cytoplasmic incompatibility is associated with impaired histone deposition in the male pronucleus
    Frédéric Landmann
    Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, USA
    PLoS Pathog 5:e1000343. 2009
    ..These results have important implications for the mechanism of Rescue and other Wolbachia-induced phenotypes...