Stephanie R Land

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Neurotoxicity from oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: NSABP C-07
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project Operations Office and Biostatistical Center, Pittsburgh, PA 15213, USA
    J Clin Oncol 25:2205-11. 2007
  2. ncbi request reprint Patient-reported symptoms and quality of life during treatment with tamoxifen or raloxifene for breast cancer prevention: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project NSABP Operations and Biostatistical Centers, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    JAMA 295:2742-51. 2006
  3. pmc Patient-reported outcomes in sentinel node-negative adjuvant breast cancer patients receiving sentinel-node biopsy or axillary dissection: National Surgical Adjuvant Breast and Bowel Project phase III protocol B-32
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistics Center, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Clin Oncol 28:3929-36. 2010
  4. ncbi request reprint Compliance with patient-reported outcomes in multicenter clinical trials: methodologic and practical approaches
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Pittsburgh, PA 15213, USA
    J Clin Oncol 25:5113-20. 2007
  5. pmc Menstrual history and quality-of-life outcomes in women with node-positive breast cancer treated with adjuvant therapy on the NSABP B-30 trial
    Patricia A Ganz
    National Surgical Adjuvant Breast and Bowel Project Operations Center NSABP, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    J Clin Oncol 29:1110-6. 2011
  6. ncbi request reprint Quality of life in operable colon cancer patients receiving oral compared with intravenous chemotherapy: results from National Surgical Adjuvant Breast and Bowel Project Trial C-06
    Jacek A Kopec
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Pittsburgh, PA, USA
    J Clin Oncol 25:424-30. 2007
  7. doi request reprint Amenorrhea in premenopausal women on the doxorubicin-and-cyclophosphamide-followed-by-docetaxel arm of NSABP B-30 trial
    Sandra M Swain
    National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, PA, USA
    Breast Cancer Res Treat 113:315-20. 2009
  8. doi request reprint Body mass index and the risk for developing invasive breast cancer among high-risk women in NSABP P-1 and STAR breast cancer prevention trials
    Reena S Cecchini
    National Surgical Adjuvant Breast and Bowel Project NSABP Operations and Biostatistical Center, One Sterling Plaza, 201 N Craig St, Suite 350, Pittsburgh, PA 15213, USA
    Cancer Prev Res (Phila) 5:583-92. 2012
  9. ncbi request reprint Relationship between arm morbidity and patient-reported outcomes following surgery in women with node-negative NSABP protocol B-32
    Jacek A Kopec
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Center, Pittsburgh, Pennsylvania, USA
    J Support Oncol 11:22-30. 2013
  10. ncbi request reprint Is sentinel node biopsy necessary in conservatively treated DCIS?
    Thomas B Julian
    National Surgical Adjuvant Breast and Bowel Project Operations Office and Biostatistical Center, Pittsburgh, Pennsylvania, USA
    Ann Surg Oncol 14:2202-8. 2007

Detail Information

Publications53

  1. ncbi request reprint Neurotoxicity from oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: NSABP C-07
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project Operations Office and Biostatistical Center, Pittsburgh, PA 15213, USA
    J Clin Oncol 25:2205-11. 2007
    ..Definitive analysis revealed an increase in 4-year disease-free survival from 67.0% to 73.2% in favor of FLOX. This study compares neurotoxicity between the treatments...
  2. ncbi request reprint Patient-reported symptoms and quality of life during treatment with tamoxifen or raloxifene for breast cancer prevention: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project NSABP Operations and Biostatistical Centers, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    JAMA 295:2742-51. 2006
    ..Tamoxifen has been approved for breast cancer risk reduction in high-risk women, but how raloxifene compares with tamoxifen is unknown...
  3. pmc Patient-reported outcomes in sentinel node-negative adjuvant breast cancer patients receiving sentinel-node biopsy or axillary dissection: National Surgical Adjuvant Breast and Bowel Project phase III protocol B-32
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistics Center, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Clin Oncol 28:3929-36. 2010
    ..We report the definitive patient-reported outcomes (PRO) comparisons...
  4. ncbi request reprint Compliance with patient-reported outcomes in multicenter clinical trials: methodologic and practical approaches
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Pittsburgh, PA 15213, USA
    J Clin Oncol 25:5113-20. 2007
    ..We describe the effectiveness of several interventions and of observational factors...
  5. pmc Menstrual history and quality-of-life outcomes in women with node-positive breast cancer treated with adjuvant therapy on the NSABP B-30 trial
    Patricia A Ganz
    National Surgical Adjuvant Breast and Bowel Project Operations Center NSABP, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    J Clin Oncol 29:1110-6. 2011
    ..The National Surgical Adjuvant Breast and Bowel Project B-30 trial included menstrual history (MH) and quality-of-life (QOL) studies to compare treatments on these outcomes...
  6. ncbi request reprint Quality of life in operable colon cancer patients receiving oral compared with intravenous chemotherapy: results from National Surgical Adjuvant Breast and Bowel Project Trial C-06
    Jacek A Kopec
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Pittsburgh, PA, USA
    J Clin Oncol 25:424-30. 2007
    ....
  7. doi request reprint Amenorrhea in premenopausal women on the doxorubicin-and-cyclophosphamide-followed-by-docetaxel arm of NSABP B-30 trial
    Sandra M Swain
    National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, PA, USA
    Breast Cancer Res Treat 113:315-20. 2009
    ..These results can be used to inform premenopausal women about the risk and time course of amenorrhea associated with this common adjuvant therapy regimen, along with the effects on symptoms and QOL...
  8. doi request reprint Body mass index and the risk for developing invasive breast cancer among high-risk women in NSABP P-1 and STAR breast cancer prevention trials
    Reena S Cecchini
    National Surgical Adjuvant Breast and Bowel Project NSABP Operations and Biostatistical Center, One Sterling Plaza, 201 N Craig St, Suite 350, Pittsburgh, PA 15213, USA
    Cancer Prev Res (Phila) 5:583-92. 2012
    ....
  9. ncbi request reprint Relationship between arm morbidity and patient-reported outcomes following surgery in women with node-negative NSABP protocol B-32
    Jacek A Kopec
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Center, Pittsburgh, Pennsylvania, USA
    J Support Oncol 11:22-30. 2013
    ..The impact of arm morbidity following breast cancer surgery on patient-observed changes in daily functioning and health-related quality of life (HRQoL) has not been well-studied...
  10. ncbi request reprint Is sentinel node biopsy necessary in conservatively treated DCIS?
    Thomas B Julian
    National Surgical Adjuvant Breast and Bowel Project Operations Office and Biostatistical Center, Pittsburgh, Pennsylvania, USA
    Ann Surg Oncol 14:2202-8. 2007
    ..Its use in patients with DCIS versus local excision (LE), observation, and/or breast irradiation remains in question...
  11. doi request reprint Long-term results of a phase II trial of neoadjuvant chemotherapy followed by esophagectomy for locally advanced esophageal neoplasm
    Arjun Pennathur
    Heart, Lung, and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 85:1930-6; discussion 1936-7. 2008
    ..We report the long-term results of our phase II study of neoadjuvant chemotherapy, followed by esophagectomy and adjuvant chemotherapy for potentially resectable esophageal carcinoma...
  12. ncbi request reprint Health-related quality of life in axillary node-negative, estrogen receptor-negative breast cancer patients undergoing AC versus CMF chemotherapy: findings from the National Surgical Adjuvant Breast and Bowel Project B-23
    Stephanie R Land
    NSABP Biostatistical Center, Pittsburgh, USA Department of Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA
    Breast Cancer Res Treat 86:153-64. 2004
    ..QOL information was considered especially relevant given the possibility that the two chemotherapy regimens would prove equivalent in terms of clinical outcome...
  13. doi request reprint Impact of IFNalpha2b upon pSTAT3 and the MEK/ERK MAPK pathway in melanoma
    Wenjun Wang
    Department of Medicine, Division of Hematology Oncology, University of Pittsburgh, Hillman Cancer Center, Research Pavilion, Suite 1 32, 5117 Centre Avenue, Pittsburgh, PA 15213 2584, USA
    Cancer Immunol Immunother 57:1315-21. 2008
    ..We have therefore evaluated STAT3 and MEK/ERK MAP kinases in patients with regional lymph node metastasis (stage IIIB) of melanoma in the context of a prospective neoadjuvant trial of HDI (UPCI 00-008)...
  14. pmc Combined analysis of estrogen receptor beta-1 and progesterone receptor expression identifies lung cancer patients with poor outcome
    Laura P Stabile
    Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Clin Cancer Res 17:154-64. 2011
    ..Steroid hormones and growth factors affect lung cancer, and it is possible they act in concert to influence patient outcome...
  15. pmc Cigarette smoking, obesity, physical activity, and alcohol use as predictors of chemoprevention adherence in the National Surgical Adjuvant Breast and Bowel Project P-1 Breast Cancer Prevention Trial
    Stephanie R Land
    National Surgical Adjuvant Breast and Bowel Project NSABP Operations and Biostatistical Centers, University of Pittsburgh, PA, USA
    Cancer Prev Res (Phila) 4:1393-400. 2011
    ..001; OR = 1.5 high vs. low) predicted adequate adherence at 36 months. There were no significant associations with obesity or physical activity. Alcohol use and smoking might indicate a need for greater adherence support...
  16. pmc CYP2A6 genotype and smoking behavior in current smokers screened for lung cancer
    Mindi A Styn
    Department of Health and Community Systems, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania 15261, USA
    Subst Use Misuse 48:490-4. 2013
    ..016). Reduced metabolism genotypes appeared unrelated to quitting. Though related to smoking dose, CYP2A6 may not influence cessation...
  17. ncbi request reprint Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b
    Wenjun Wang
    Department of Medicine, Division of Hematology Oncology, University of Pittsburgh, Melanoma and Skin Cancer Program, University of Pittsburgh Cancer Institute Pittsburgh, PA, USA
    Clin Cancer Res 13:1523-31. 2007
    ..The goal of this study was to understand the effects of high-dose IFNalpha2b (HDI) in relation to the balance of pSTAT1 and pSTAT3...
  18. pmc Prevention of tobacco carcinogen-induced lung cancer in female mice using antiestrogens
    Laura P Stabile
    Department of Pharmacology and Chemical Biology, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA
    Carcinogenesis 33:2181-9. 2012
    ..ERβ expressed by inflammatory and neoplastic epithelial cells in the lung may signal in response to local estrogen production...
  19. doi request reprint Long-term neurotoxicity effects of oxaliplatin added to fluorouracil and leucovorin as adjuvant therapy for colon cancer: results from National Surgical Adjuvant Breast and Bowel Project trials C-07 and LTS-01
    Kelley M Kidwell
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Pittsburgh, Pennsylvania 15213, USA
    Cancer 118:5614-22. 2012
    ....
  20. doi request reprint Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients
    Julien Fourcade
    Department of Medicine, Division of Hematology Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2582, USA
    J Immunother 31:781-91. 2008
    ..They also suggest that the presence of tumor-induced NY-ESO-1-specific T cells of well-defined clonotypes is critical for the expansion of tumor-reactive NY-ESO-1-specific CD8+ T cells after peptide-based vaccine strategies...
  21. ncbi request reprint Pathologic variables predictive of breast events in patients with ductal carcinoma in situ
    Edwin R Fisher
    National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, USA
    Am J Clin Pathol 128:86-91. 2007
    ..The similar predictive role of comedo necrosis in this study and that reported previously from NSABP B-17 (total of 2,079 patients) strongly supports its role as a simple high-risk predictor for ipsilateral breast tumor recurrences...
  22. pmc Association of cigarette smoking and media literacy about smoking among adolescents
    Brian A Primack
    Division of General Internal Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Adolesc Health 39:465-72. 2006
    ..To determine whether media literacy concerning tobacco use is independently associated with two clinically relevant outcome measures in adolescents: current smoking and susceptibility to smoking...
  23. ncbi request reprint Symptom measurement in the Breast Cancer Prevention Trial (BCPT) (P-1): psychometric properties of a new measure of symptoms for midlife women
    David Cella
    National Surgical Adjuvant Breast and Bowel Project NSABP, Pittsburgh, PA, USA
    Breast Cancer Res Treat 109:515-26. 2008
    ..To evaluate scalability of a symptom scale administered to women enrolled in the Breast Cancer Prevention Trial (BCPT) (P-1) conducted by the National Surgical Adjuvant Breast and Bowel Project (NSABP)...
  24. doi request reprint Adolescents' experiences using the contraceptive patch versus pills
    Gina S Sucato
    Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Pediatr Adolesc Gynecol 24:197-203. 2011
    ..To compare use of the weekly transdermal contraceptive patch (patch) with daily combined hormonal contraceptive pills (pills) in adolescents...
  25. pmc Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors
    Ji Young Song
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
    Cancer Epidemiol 37:518-22. 2013
    ..To investigate the association between inherited variation in the estrogen receptor beta (ERβ) gene (ESR2) and ERβ lung tumor expression, a phenotype that possibly affects survival differently in men and women...
  26. pmc Smoking behavior 1 year after computed tomography screening for lung cancer: Effect of physician referral for abnormal CT findings
    Mindi A Styn
    Department of Health and Community Systems, University of Pittsburgh School of Nursing, PA, USA
    Cancer Epidemiol Biomarkers Prev 18:3484-9. 2009
    ..Focusing on outcomes related to the reporting of CT abnormality, we examined the natural history of smoking in the Pittsburgh Lung Screening Study...
  27. pmc Adolescent smoking and volume of exposure to various forms of media
    Brian A Primack
    Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Public Health 122:379-89. 2008
    ..To assess the association between adolescent smoking and volume of exposure to various forms of media after controlling for multiple relevant covariates...
  28. ncbi request reprint An association between postoperative radiotherapy for primary breast cancer in 11 National Surgical Adjuvant Breast and Bowel Project (NSABP) studies and the subsequent appearance of pleural mesothelioma
    Melvin Deutsch
    UPMC Presbyterian Department of Radiation Oncology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Clin Oncol 30:294-6. 2007
    ....
  29. pmc Association between media use in adolescence and depression in young adulthood: a longitudinal study
    Brian A Primack
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, 230 McKee Place, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 66:181-8. 2009
    ..Although certain media exposures have been linked to the presence of psychiatric conditions, few studies have investigated the association between media exposure and depression...
  30. pmc PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients
    Julien Fourcade
    Department of Medicine and Division of Hematology Oncology, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA
    J Immunol 182:5240-9. 2009
    ..They further support the use of PD-1/PD-L1 pathway blockade in cancer patients to partially restore NY-ESO-1-specific CD8(+) T cell numbers and functions, increasing the likelihood of tumor regression...
  31. pmc Estrogen receptor beta functions through nongenomic mechanisms in lung cancer cells
    Guangfeng Zhang
    University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, Pennsylvania 15213, USA
    Mol Endocrinol 23:146-56. 2009
    ..In conclusion, our results suggest that that proliferative effects of estrogen in lung cancer cells is mediated primarily, if not exclusively, by the nongenomic action of ERbeta...
  32. doi request reprint Chemoimmunotherapy with low-dose fludarabine and cyclophosphamide and high dose rituximab in previously untreated patients with chronic lymphocytic leukemia
    Kenneth A Foon
    Department of Medicine and Biostatistics, University of Pittsburgh School of Medicine, Graduate School of Public Health, University of Pittsburgh Cancer Institute, University of Pittsburgh Medical Center Cancer Centers, PA, USA
    J Clin Oncol 27:498-503. 2009
    ..However, grade 3/4 neutropenia was reported in 52% of cycles of treatment. The purpose of this trial was to maintain the high responses but reduce the toxicity of FCR by decreasing the fludarabine and cyclophosphamide (FCR-Lite)...
  33. doi request reprint Phase II trial of short-course CHOP-R followed by 90Y-ibritumomab tiuxetan and extended rituximab in previously untreated follicular lymphoma
    Samuel A Jacobs
    Department of Medicine, University of Pittsburgh Medical Center Cancer Centers, Pittsburgh, Pennsylvania 15232, USA
    Clin Cancer Res 14:7088-94. 2008
    ....
  34. ncbi request reprint The incidence of lung carcinoma after surgery for breast carcinoma with and without postoperative radiotherapy. Results of National Surgical Adjuvant Breast and Bowel Project (NSABP) clinical trials B-04 and B-06
    Melvin Deutsch
    Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Cancer 98:1362-8. 2003
    ....
  35. ncbi request reprint Elevated hepatocyte growth factor level correlates with poor outcome in early-stage and late-stage adenocarcinoma of the lung
    Jill M Siegfried
    Department of Pharmacology, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213 1863, USA
    Chest 125:116S-9S. 2004
  36. pmc Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis
    Laura P Stabile
    Department of Pharmacology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Mol Cancer Ther 7:1913-22. 2008
    ..These preclinical results show that blocking the HGF/c-Met interaction with a single monoclonal antibody delivered systemically can have profound inhibitory effects on development of lung tumors...
  37. pmc The impact of genetic variation in DRD2 and SLC6A3 on smoking cessation in a cohort of participants 1 year after enrollment in a lung cancer screening study
    Mindi A Styn
    Department of Health and Community Systems, University of Pittsburgh School of Nursing, Pennsylvania, USA
    Am J Med Genet B Neuropsychiatr Genet 150:254-61. 2009
    ..The association between DRD2 TaqIA and smoking cessation supports the hypothesis that genetic variation in the dopamine pathway influences smoking cessation...
  38. pmc Development and validation of a smoking media literacy scale for adolescents
    Brian A Primack
    Center for Research on Health Care, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, 230 McKee Place, Ste 600, Pittsburgh, PA 15213, USA
    Arch Pediatr Adolesc Med 160:369-74. 2006
    ..To develop a smoking media literacy (SML) scale by using empiric survey data from a large sample of high school students and to assess reliability and criterion validity of the scale...
  39. ncbi request reprint What do patients want from their radiation oncologist? Initial results from a prospective trial
    Ajay K Bhatnagar
    Department of Radiation Oncology, University of Pittsburgh Cancer Institute University of Pittsburgh Medical Center Cancer Centers, Pittsburgh, PA 15232, USA
    Int J Radiat Oncol Biol Phys 69:1527-33. 2007
    ..To assess patients' initial physician preferences using a newly developed instrument...
  40. ncbi request reprint Association of the EGFR intron 1 CA repeat length with lung cancer risk
    Weiping Zhang
    Department of Pharmacology, University of Pittsburgh Cancer Institute, SPORE in Lung Cancer, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 1863, USA
    Mol Carcinog 46:372-80. 2007
    ..Our study, which is preliminary, demonstrates for the first time that shorter EGFR-CA repeats associate with lung cancer risk. The number of EGFR-CA repeats identifies a possible susceptible population to lung cancer...
  41. ncbi request reprint Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: twelve-year observations concerning lobular carcinoma in situ
    Edwin R Fisher
    Pathology Center, National Surgical Adjuvant Breast and Bowel Project Pathology Center, Pittsburgh, Pennsylvania, USA
    Cancer 100:238-44. 2004
    ..The current report represents a 12-year clinicopathologic update of an earlier 5-year analysis of 180 patients with lobular carcinoma in situ (LCIS) who were treated with local excision and subsequent surveillance only...
  42. ncbi request reprint Thoracic epidural versus intercostal nerve catheter plus patient-controlled analgesia: a randomized study
    James D Luketich
    Division of Thoracic and Foregut Surgery, Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Ann Thorac Surg 79:1845-9; discussion 1849-50. 2005
    ..Debate exists over the optimal pain control method. This randomized trial was designed to compare epidural (EPI) and intercostal nerve catheter with patient-controlled analgesia (ICN-PCA) for pain control after thoracotomy...
  43. pmc Volume of tobacco advertising in African American markets: systematic review and meta-analysis
    Brian A Primack
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Public Health Rep 122:607-15. 2007
    ..This study compared the concentration (proportion of media messages that are for tobacco) and density (pro-tobacco media messages per person) of pro-tobacco media messages between African American and Caucasian markets...
  44. ncbi request reprint Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses
    Stergios J Moschos
    Melanoma and Skin Cancer Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Clin Oncol 24:3164-71. 2006
    ..Therefore, HDI was investigated in the neoadjuvant setting to assess clinical and pathologic responses after 4 weeks of HDI and to perform immunohistochemical evaluation of immune cell subsets and melanoma-associated antigens...
  45. pmc Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth
    A McGarry Houghton
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Nat Med 16:219-23. 2010
    ..Additionally, to our knowledge, this is the first description of a secreted proteinase gaining access to the inside of a cell and altering intracellular signaling...
  46. pmc Associations of mental health problems with waterpipe tobacco and cigarette smoking among college students
    Brian A Primack
    Medicine and Pediatrics, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Subst Use Misuse 48:211-9. 2013
    ..For comparison, cigarette smoking was also examined. Associations with mental health variables were very strong for cigarette smoking but only moderate for waterpipe smoking. Study implications and limitations are noted...
  47. ncbi request reprint Evaluation of anticyclin B1 serum antibody as a diagnostic and prognostic biomarker for lung cancer
    Ann Marie Egloff
    University of Pittsburgh School of Medicine, E1040 Biomedical Science Tower, Pittsburgh, PA 15261, USA
    Ann N Y Acad Sci 1062:29-40. 2005
    ....
  48. ncbi request reprint Funding patient-reported outcomes in cancer clinical trials
    Carol M Moinpour
    Southwest Oncology Group Statistical Center Fred Hutchinson Cancer Research Center, Seattle, WA 98104 1024, USA
    J Clin Oncol 25:5100-5. 2007
    ....
  49. doi request reprint Benefit from exemestane as extended adjuvant therapy after 5 years of adjuvant tamoxifen: intention-to-treat analysis of the National Surgical Adjuvant Breast And Bowel Project B-33 trial
    Eleftherios P Mamounas
    Aultman Health Foundation, 2600 6th St, SW Canton, OH 44710, USA
    J Clin Oncol 26:1965-71. 2008
    ....
  50. doi request reprint Missing patient-reported outcome data in an adjuvant lung cancer study
    Stephanie R Land
    J Clin Oncol 26:5018-9. 2008
  51. ncbi request reprint Endostatin plus interferon-alpha2b therapy for metastatic melanoma: a novel combination of antiangiogenic and immunomodulatory agents
    Stergios J Moschos
    Melanoma and Skin Cancer Program, University of Pittsburgh Cancer Institute, PA 15213 2584, USA
    Melanoma Res 17:193-200. 2007
    ..Better laboratory correlates of antiangiogenic response are needed, and the predictive value of circulating endothelial cells warrants further evaluation...
  52. pmc Mammographic density and breast cancer after ductal carcinoma in situ
    Laurel A Habel
    Division of Research, Kaiser Permanente Medical Care Program, Oakland, CA 94612, USA
    J Natl Cancer Inst 96:1467-72. 2004
    ..Our results provide initial evidence that the risk of second breast cancers may be increased among DCIS patients with highly dense breasts...
  53. doi request reprint Statistics in oncology
    Stephanie R Land
    J Clin Oncol 26:3668. 2008