Research Topics
| L W LampsSummaryAffiliation: University of Arkansas for Medical Sciences Country: USA Publications
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Publications
Infectious causes of appendicitisLaura W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Infect Dis Clin North Am 24:995-1018, ix-x. 2010..Pertinent ancillary diagnostic techniques and the clinical context and significance of the various infections are also discussed...
Molecular diagnosis of Campylobacter jejuni infection in cases of focal active colitisElizabeth N Schneider
Department of Pathology, Central Arkansas Veterans Healthcare System, Little Rock, AR 72205, and Department of Pathology, University of Michigan Health System, Ann Arbor, MI, USA
Am J Surg Pathol 30:782-5. 2006..Furthermore, PCR analysis performed on fixed, routinely processed colon biopsies is an excellent diagnostic method for detection of this organism...
Infective disorders of the gastrointestinal tractL W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Histopathology 50:55-63. 2007....
Appendicitis and infections of the appendixLaura W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
Semin Diagn Pathol 21:86-97. 2004....
Diverticular disease-associated segmental colitisLaura W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72212, USA
Clin Gastroenterol Hepatol 5:27-31. 2007....
Hepatic granulomas, with an emphasis on infectious causesLaura W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Adv Anat Pathol 15:309-18. 2008....
Histologic and molecular diagnosis of tularemia: a potential bioterrorism agent endemic to North AmericaLaura W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Mod Pathol 17:489-95. 2004..This PCR assay, the first designed for use in processed tissues, is an excellent method for diagnosis of tularemia...
Pathology of food-borne infectious diseases of the gastrointestinal tract: an updateLaura W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock 72205, USA
Adv Anat Pathol 10:319-27. 2003....
Characterization of interdigital glands in the Asian elephant (Elephas maximus)L W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
Res Vet Sci 71:197-200. 2001..Both the histochemical and immunohistochemical staining patterns are analogous to human eccrine structures. This study shows with certainty that Asian elephants possess sweat glands as they are defined histologically...
Pathogenic Yersinia DNA is detected in bowel and mesenteric lymph nodes from patients with Crohn's diseaseLaura W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock 72212, USA
Am J Surg Pathol 27:220-7. 2003..Like previous studies associating infectious organisms with CD, much work remains to elucidate whether the presence of DNA is an epiphenomenon or actually a factor in the pathogenesis of CD...
The role of Yersinia enterocolitica and Yersinia pseudotuberculosis in granulomatous appendicitis: a histologic and molecular studyL W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock 72205, USA
Am J Surg Pathol 25:508-15. 2001..Because special stains and cultures are often not diagnostic, PCR analysis is an excellent technique for the diagnosis of Yersinia...
Molecular detection of Campylobacter jejuni in archival cases of acute appendicitisLucas K Campbell
Department of Pathology, University of Chicago, IL, USA
Mod Pathol 19:1042-6. 2006..Further study is needed to determine whether the presence of C. jejuni DNA in acute appendicitis indicates appendiceal involvement by C. jejuni enteritis, or if there is a true causative role for C. jejuni in acute appendicitis...
The coexistence of low-grade mucinous neoplasms of the appendix and appendiceal diverticula: a possible role in the pathogenesis of pseudomyxoma peritoneiL W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock 72205, USA
Mod Pathol 13:495-501. 2000..Either mechanism might allow low-grade mucinous neoplasms to penetrate the appendiceal wall more easily...
Tumour necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: a kinetic study of proliferating cell nuclear antigen and cytokine expressionLaura P James
Department of Paediatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
Basic Clin Pharmacol Toxicol 97:8-14. 2005..Depletion of tumour necrosis factor receptor 1 has long-lasting effects on hepatocyte regeneration in acetaminophen toxicity but multiple other factors appear to orchestrate eventual recovery in these mice...
Necrolytic migratory erythema as the only presenting sign of a glucagonomaSandra Marchese Johnson
Departments of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
J Am Acad Dermatol 49:325-8. 2003..Neither the clinical eruption nor the tumor has recurred for 6 months. The course of disease confirms the diagnosis of necrolytic migratory erythema associated with a glucagonoma...
Pathologists in a teaching institution assess the value of the autopsyIlene B Bayer-Garner
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Arch Pathol Lab Med 126:442-7. 2002..With the advent of modern diagnostic technology, use of the autopsy as a means of assessing diagnostic accuracy has declined precipitously. Interestingly, during the same period, the rate of misdiagnosis found at autopsy has not changed...
Renal sclerosing peritubular nodules in a patient with neurofibromatosis type 2: a case report with immunohistochemical and electron microscopic studiesNeriman Gokden
University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Hum Pathol 40:1650-4. 2009..We examined these peritubular proliferations with immunohistochemistry, histochemistry, and electron microscopy and compared our findings with the previous report in the literature...
Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formationLaura P James
Clinical Pharmacology Toxicology, Department of Pediatrics, Arkansas Children s Hospital, 800 Marshall Street, Little Rock, AR 72202, USA
Toxicol Sci 75:458-67. 2003..IL-6, MIP-2, and MCP-1 appear to follow the toxicity. While it is a pre-requisite event, covalent binding per se does not appear to be a toxic event in the development of toxicity...
Interleukin 6 and hepatocyte regeneration in acetaminophen toxicity in the mouseLaura P James
Department of Pediatrics, Univerisity of Arkansas for Medical Sciences, Little Rock, AR, USA
Biochem Biophys Res Commun 309:857-63. 2003..Pretreatment of KO mice with IL-6 lowered AST and normalized PCNA staining in the IL-6 KO mice. These data suggest that IL-6 is important in hepatocyte regeneration following APAP toxicity in the mouse...
Molecular biogrouping of pathogenic Yersinia enterocolitica: development of a diagnostic PCR assay with histologic correlationLaura W Lamps
Department of Pathology, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, AR 72205, USA
Am J Clin Pathol 125:658-64. 2006....
Optimal screening and diagnosis of microsporida in tissue sections: a comparison of polarization, special stains, and molecular techniquesL W Lamps
Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 5310, USA
Am J Clin Pathol 109:404-10. 1998..Furthermore, combining Brown-Brenn or Warthin-Starry with the trichrome stain helps exclude false-positive results due to granular artifacts (eg, eosinophils, Paneth cells)...
Vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicityBrian Donahower
Department of Pharmacology, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Am J Physiol Gastrointest Liver Physiol 291:G102-9. 2006..These data indicate that endogenous VEGF is critically important to the process of hepatocyte regeneration in APAP-induced hepatotoxicity in the mouse...
Differential expression of insulin-like growth factor binding protein-5 in pancreatic adenocarcinomas: identification using DNA microarraySarah K Johnson
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205 7199, USA
Mol Carcinog 45:814-27. 2006..As a potential modulator of cell proliferation, the overexpression of IGFBP-5 may, therefore, play a significant role in the malignant transformation of normal pancreatic epithelial cells...
Amiodarone induced liver cirrhosis. Report of two casesMuslim Atiq
Division of Gastroenterology and General Medicine, Department of Internal Medicine, University of Arkansas for Medical Sciences, USA
J Gastrointestin Liver Dis 18:233-5. 2009..We present two cases of liver cirrhosis in patients taking amiodarone. Their clinical presentation as well as histological features are discussed in detail...
Ischemic duodenal ulcer, an unusual presentation of sickle cell diseaseRahul N Julka
Division of Gastroenterology, University of Arkansas for Medical Sciences, Fayette, AR, USA
J Natl Med Assoc 100:339-41. 2008..Prompt endoscopic and/or urgent surgical intervention should be considered, particularly if anticoagulation is an issue, as proton pump inhibitor use is ineffective in healing this type of ulcer...
The diagnostic value of hepatocyte paraffin antibody 1 in differentiating hepatocellular neoplasms from nonhepatic tumors: a reviewLaura W Lamps
University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Adv Anat Pathol 10:39-43. 2003....
Evaluation of immunohistochemistry in identifying Bartonella henselae in cat-scratch diseaseGabriel C Caponetti
Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA, USA
Am J Clin Pathol 131:250-6. 2009..The diagnostic sensitivity of these 3 tests is low for CSD. SSS seems to be the most sensitive test but is the least specific. PCR is more sensitive than IHC and may, therefore, serve as a helpful second-line test on all IHC- cases...
Recurrent spontaneous gastrointestinal graft-versus-host disease in autologous hematopoietic stem cell transplantationSomashekar G Krishna
Department of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock 72211, USA
Clin Lymphoma Myeloma Leuk 10:E17-21. 2010..We report for the first time a patient with spontaneous recurrent GI GVHD after autoHSCT for multiple myeloma with predominant lower GI symptoms and excellent response to enteric-coated budesonide therapy...
Isolated gastric malakoplakia: a case report and review of the literatureLastra-Camacho Gustavo
Department of Pathology, Yale University School of Medicine, New Haven, Conn 06520-8070, USA
Arch Pathol Lab Med 128:e153-6. 2004..Follow-up examination 12 months later revealed no endoscopic or histologic improvement...
Rab11a immunohistochemical analysis does not distinguish indefinite, low-, and high-grade dysplasia in Barrett esophagusMarie E Robert
Department of Pathology, Yale University, New Haven, CT 06520, USA
Am J Clin Pathol 124:519-27. 2005..Rab11a immunoreactivity did not enhance the diagnostic assessment of dysplasia in Barrett esophagus. The previously reported positive correlation of p53 immunoreactivity with the presence of dysplasia in Barrett esophagus was confirmed...
Uncommon malignancies: case 2. Gastric choriocarcinomaDaniel W Dye
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, USA
J Clin Oncol 23:6251-3. 2005
Histiocytic subpopulations in the gastrointestinal tract: distribution and possible relationship to functionElizabeth N Schneider
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
Appl Immunohistochem Mol Morphol 12:356-9. 2004..Further studies are needed to explore the relation between specific histiocyte subsets and gastrointestinal disease processes...
Research Grants
- EXPERIMENTAL PATHOLOGY SHARED RESOURCE LABORATORYLaura Lamps; Fiscal Year: 2003..abstract_text> ..
