Doris Lambracht-Washington

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease
    Doris Lambracht-Washington
    Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, United States
    J Neuroimmunol 254:63-8. 2013
  2. pmc Advances in the development of vaccines for Alzheimer's disease
    Doris Lambracht-Washington
    Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Discov Med 15:319-26. 2013
  3. pmc DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation
    Doris Lambracht-Washington
    Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9036, USA
    Cell Mol Neurobiol 31:867-74. 2011
  4. pmc DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model
    Doris Lambracht-Washington
    Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9108, USA
    JAMA 302:1796-802. 2009
  5. pmc Analysis of three plasmid systems for use in DNA A beta 42 immunization as therapy for Alzheimer's disease
    Bao Xi Qu
    Alzheimer s Disease Center, Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9036, USA
    Vaccine 28:5280-7. 2010
  6. pmc Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet
    Petra D Cravens
    Department of Neurology, University of Texas Southwestern Medical Center at Dallas, TX, USA
    J Neuroinflammation 8:73. 2011

Collaborators

Detail Information

Publications6

  1. ncbi request reprint A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease
    Doris Lambracht-Washington
    Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, United States
    J Neuroimmunol 254:63-8. 2013
    ....
  2. pmc Advances in the development of vaccines for Alzheimer's disease
    Doris Lambracht-Washington
    Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Discov Med 15:319-26. 2013
    ..Since 2000 a number of clinical trials for AD immunotherapy have started, have failed, and are continuing to be pursued. This article will review these clinical trials and ongoing research in this regard...
  3. pmc DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation
    Doris Lambracht-Washington
    Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9036, USA
    Cell Mol Neurobiol 31:867-74. 2011
    ..Therefore, Aβ42 DNA trimer immunization has a high probability to be effective and safe to treat patients with early AD...
  4. pmc DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model
    Doris Lambracht-Washington
    Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9108, USA
    JAMA 302:1796-802. 2009
    ....
  5. pmc Analysis of three plasmid systems for use in DNA A beta 42 immunization as therapy for Alzheimer's disease
    Bao Xi Qu
    Alzheimer s Disease Center, Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9036, USA
    Vaccine 28:5280-7. 2010
    ..These results demonstrate the potential therapeutic use of Gal4/UAS DNA A beta 42 trimer immunization in preventing Alzheimer's disease...
  6. pmc Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet
    Petra D Cravens
    Department of Neurology, University of Texas Southwestern Medical Center at Dallas, TX, USA
    J Neuroinflammation 8:73. 2011
    ..Our data further suggest that GM-CSF expression by CD4+ T cells regulated by IL-23 contributes to their encephalitogenicity in our EAE model...