J S Lambert
Affiliation: University of Maryland
- Antibody to human immunodeficiency virus type 1 (HIV-1) gp160 in mucosal specimens of asymptomatic HIV-1-infected volunteers parenterally immunized with an experimental recombinant HIV-1 IIIB gp160 vaccine. The National Institute of Allergy and InfectiousJ S Lambert
The Institute of Human Virology, University of Maryland at Baltimore School of Medicine, 21201, USA
Clin Diagn Lab Immunol 4:302-8. 1997..Fewer volunteers expressed anti-LAI rgp160 IgA antibodies in mucosal or serum specimens: 11 of 22 parotid saliva specimens, 3 of 11 SP specimens, 3 of 5 CVL samples, and 12 of 22 sera...
- HIV vaccines in infants and childrenJohn S Lambert
University of Maryland Institute of Human Virology, Baltimore, USA
Paediatr Drugs 7:267-76. 2005..However, to date, candidate HIV vaccines capable of generating robust immunologic responses in these populations have been disappointing...
- A pilot study to evaluate the safety and feasibility of the administration of AZT/3TC fixed dose combination to HIV infected pregnant women and their infants in Rio de Janeiro, BrazilJ S Lambert
University of Maryland Institute of Human Virology, Baltimore, Maryland, USA
Sex Transm Infect 79:448-52. 2003..To evaluate the safety and feasibility of zidovudine and lamivudine (AZT/3TC) given to HIV infected pregnant women and their infants in Rio de Janeiro, Brazil...
- Performance characteristics of HIV-1 culture and HIV-1 DNA and RNA amplification assays for early diagnosis of perinatal HIV-1 infectionJohn S Lambert
Institute of Human Virology, University of Maryland, Baltimore, USA
J Acquir Immune Defic Syndr 34:512-9. 2003..Given that RNA assays require less blood volume and yield rapid results, our study adds to existing data suggesting that RNA assays may be used for early diagnosis of HIV-1 infection in infants...
- Safety and immunogenicity of HIV recombinant envelope vaccines in HIV-infected infants and children. National Institutes of Health-sponsored Pediatric AIDS Clinical Trials Group (ACTG-218)J S Lambert
The Johns Hopkins University, Baltimore, Maryland, USA
J Acquir Immune Defic Syndr Hum Retrovirol 19:451-61. 1998..The rgp160 and gp120 subunit vaccines were safe and immunogenic in this population...
- A Phase I safety and immunogenicity trial of UBI microparticulate monovalent HIV-1 MN oral peptide immunogen with parenteral boost in HIV-1 seronegative human subjectsJ S Lambert
Institute of Human Virology, University of Maryland, 725 West Lombard Street, Baltimore, MD21201, USA
Vaccine 19:3033-42. 2001..No serious adverse experiences were observed. Oral administration of this vaccine, alone or in combination with parenteral boosting, resulted in no significant humoral, cellular, or mucosal immune responses...
- Comparison of the safety, vaccine virus shedding, and immunogenicity of influenza virus vaccine, trivalent, types A and B, live cold-adapted, administered to human immunodeficiency virus (HIV)-infected and non-HIV-infected adultsJ C King
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
J Infect Dis 181:725-8. 2000..The data suggest that inadvertent vaccination with LAIV in relatively asymptomatic HIV-infected adults would not be associated with frequent significant adverse events...
- Toxoplasmic encephalitis in an HIV infected pregnant woman: successful outcome for both mother and childSusie Andries Nogueira
Clementino Fraga Filho Hospital, Federal University of Rio de Janeiro, Hospital of Lagoa, Rio de Janeiro, RJ, Brazil
Braz J Infect Dis 6:201-5. 2002....
- HIV-1 vaccine induced immune responses in newborns of HIV-1 infected mothersElizabeth J McFarland
Department of Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver Colorado, USA
AIDS 20:1481-9. 2006..This study evaluated the safety and immunogenicity of ALVAC HIV-1 vaccine with and without a subunit envelope boost in infants born to HIV-1-infected women...
- Overview of genotypic and clinical profiles of human immunodeficiency virus type 1-infected children in Rio de Janeiro, BrazilElizabeth S Machado
Serviço de Doenças Infecciosas e Parasitárias, Hospital Universitario Clementino Fraga Filho, 21941 590 Rio de Janeiro, RJ, Brazil
An Acad Bras Cienc 76:727-41. 2004..To our knowledge, this is the largest pediatric cohort ever analyzed in Brazil, and the data provided is of paramount importance to a better understanding of HIV/AIDS evolution in pediatric settings...
- Alternative, age- and viral load-related routes of nelfinavir resistance in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapyElizabeth S Machado
Serviço de Doenças Infecciosas e Parasitárias, Hospital Universitario Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, RJ, Brazil
Pediatr Infect Dis J 23:1057-9. 2004..There was a significant correlation with a higher viral load and lower age and the occurrence of L90M. These findings suggest differential molecular age- and viral load-related routes for nelfinavir resistance...
- Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapyElizabeth S Machado
Serviço de Doenças Infecciosas e Parasitárias, Hospital Universitario Clementino Fraga Filho, Rio de Janeiro, Brazil
J Clin Virol 30:24-31. 2004..However, the development of drug-resistant strains or poor adherence to therapy could impact the efficacy of this approach...
- Clinical manifestations of HIV infected childrenPurnima Madhivanan
YR Gaitonde Centerfor AIDS Research and Education, Chennai, Tamil Nadu, India
Indian J Pediatr 70:615-20. 2003..Consequently, children in India increasingly getting infected, primarily from vertical transmission. A retrospective review of the profile of HIV infected children attending an HIV clinic in South India is reported...
- Production of the HIV-suppressive chemokines CCL3/MIP-1alpha and CCL22/MDC is associated with more effective antiretroviral therapy in HIV-infected childrenJohn S Lambert
Mater Misericordiae University Hospital, University College Dublin, Dublin, Ireland
Pediatr Infect Dis J 26:935-44. 2007..Whether the release of these chemokines from lymphocytes influences treatment outcome in children receiving antiretroviral therapy is not known...
- Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficiency virus transmission and infant infectionJohn S Lambert
Institute of Human Virology, University of Maryland, Baltimore, USA
Clin Diagn Lab Immunol 12:622-31. 2005..Detailed immunophenotyping may be useful in supporting the diagnosis of HIV infection in infants with perinatal HIV exposure...
- Meeting report of the 10th European AIDS Conference (EACS) 17-20 November 2005Nicholas Chew
Mater University Hospital, University College Dublin, Ireland
J HIV Ther 10:79-80. 2005
- Hepatitis C virus transfusion-transmitted infection in Brazilian cardiac surgery patientsCristiane A Villela Nogueira
Internal Medicine and Preventive Medicine Department, Clementino Fraga Filho University Hospital, Federal Universite of Rio de Janeiro, Brazil
Clin Lab 48:529-33. 2002..27% (2/157). This study shows a high rate of HCV infection acquired post-transfusion in a cohort of surgery patients in Brazil and suggests that better screening methods such as viral RNA assessment may be effective in lowering this rate...