Research Topics
Species | Geeta LalSummaryAffiliation: University of Iowa Country: USA Publications
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Publications
Risk of subsequent primary thyroid cancer after another malignancy: latency trends in a population-based studyGeeta Lal
Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
Ann Surg Oncol 19:1887-96. 2012..To evaluate the risk of a subsequent primary thyroid cancer (SPTC) in patients with common invasive cancers, with attention to latency trends and histology associations...
Determinants of survival in patients with calciphylaxis: a multivariate analysisGeeta Lal
Department of Surgery, University of Iowa Hospitals, Iowa City, IA 52242, USA
Surgery 146:1028-34. 2009..Our study aims to assess the factors affecting survival in patients with calciphylaxis...
Extracellular matrix 1 (ECM1) expression is a novel prognostic marker for poor long-term survival in breast cancer: a Hospital-based Cohort Study in IowaGeeta Lal
Department of Surgery, University of Iowa, Iowa City, IA, USA
Ann Surg Oncol 16:2280-7. 2009..We sought to further evaluate ECM1 expression and its effect on prognosis in an unselected cohort of patients with breast cancer...
PET-CT scans in recurrent or persistent differentiated thyroid cancer: is there added utility beyond conventional imaging?Geeta Lal
Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
Surgery 148:1082-9; discussion 1089-90. 2010..Integrated positron emission tomography (PET)-computed tomography (CT) may have advantages over conventional imaging in localizing recurrent or persistent differentiated thyroid cancer...
ECM1 expression in thyroid tumors--a comparison of real-time RT-PCR and IHCGeeta Lal
Department of Surgery, Section of Surgical Oncology and Endocrine Surgery University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
J Surg Res 149:62-8. 2008..The purpose of the current study is to evaluate and compare ECM1 expression by real-time RT-PCR with immunohistochemistry (IHC) as diagnostic aids in thyroid neoplasms...
Regulation of 14-3-3sigma expression in human thyroid carcinoma is epigenetically regulated by aberrant cytosine methylationGeeta Lal
Department of Surgery, Division of Surgical Oncology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 4641 JCP, Iowa City, IA 52242, USA
Cancer Lett 267:165-74. 2008..In addition, 5-aza-dC treatment increased 14-3-3sigma expression in the FTC-238 and NPA cell lines, which had low baseline expression. We conclude 14-3-3sigma expression in thyroid carcinomas is regulated by CpG island hypermethylation...
Minimally invasive parathyroidectomy and preoperative MIBI scans: correlation of gland weight and preoperative PTHDaniel Calva Cerqueira
Department of Surgery, University of Iowa Carver College of Medicine, IA, USA
J Am Coll Surg 205:S38-44. 2007..This strategy depends on preoperative localization tests, of which the MIBI scan is the most commonly used. This study details one surgeon's MIP experience and examines factors that correlate with the results of sestamibi (MIBI) scans...
RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinomaGeeta Lal
Department of Surgery, Division of Surgical Oncology, University of Iowa, Iowa City, Iowa, USA
Cancer 107:2752-9. 2006..RIZ1 expression is lost in a variety of tumors, primarily by means of epigenetic mechanisms that involve promoter hypermethylation...
Invasion in follicular thyroid cancer cell lines is mediated by EphA2 and pAktYunxia O'Malley
Division of Surgical Oncology and Endocrine Surgery, University of Iowa Carver College of Medicine, Iowa City, IA 52242 1086, USA
Surgery 152:1218-24. 2012..Phosphorylated Akt (pAkt) plays a role in the regulation of thyroid cancer invasion and metastasis. We investigated the role of EphA2 and Akt in FTC-133 and FTC-238, 2 closely related human cell lines with differing invasive phenotypes...
Surveillance and intervention after thyroid lobectomyPhilip M Spanheimer
Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, Iowa
Ann Surg Oncol 18:1729-33. 2011..After thyroid lobectomy, many patients require ongoing care. This study sought to quantify the rates of surveillance and intervention after thyroid lobectomy...
Role for limited neck exploration in young adults with apparently sporadic primary hyperparathyroidismLaura A Adam
Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
World J Surg 32:1518-24. 2008..We hypothesized that young adults (ages 16-40 years) without familial PHPT have a disease process similar to that in older patients...
Expansion of a cell population expressing stem cell markers in parathyroid glands from patients with hyperparathyroidismSandy H Fang
Department of Surgery, University of Iowa, Iowa City, IA 52242, USA
Ann Surg 251:107-13. 2010..We sought to examine abnormal parathyroid glands for the presence of stem cells...
When is prophylactic thyroidectomy indicated for patients with the RET codon 609 mutation?Daniel Calva
Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, University of Iowa College of Medicine, Iowa City, IA, USA
Ann Surg Oncol 16:2237-44. 2009..We report a three-generation family with C609Y RET mutation where members having prophylactic or therapeutic thyroidectomy call the current recommendations for age at thyroidectomy into question...
Should total thyroidectomy become the preferred procedure for surgical management of Graves' disease?Geeta Lal
Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Thyroid 15:569-74. 2005..Total or near-total thyroidectomy obviates these disadvantages and can be performed without increased complication rates, thus appearing to be the preferred extent of thyroidectomy for Graves' disease...
Parathyroid cancerSandy H Fang
Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
Endocr Pract 17:36-43. 2011..To review the current knowledge pertaining to the etiology, molecular pathogenesis, and management of parathyroid carcinoma, a rare presentation of primary hyperparathyroidism...
Accuracy of preoperative localization studies and intraoperative parathyroid hormone assay in patients with primary hyperparathyroidism and double adenomaMehmet Haciyanli
Department of Surgery, University of California San Francisco/Mount Zion Medical Center, San Francisco, CA, USA
J Am Coll Surg 197:739-46. 2003..The combined accuracy of US, sestamibi, and IOPTH assay predicted a double adenoma in 80% of the patients...
Coagulopathy, marantic endocarditis, and cerebrovascular accidents as paraneoplastic features in medullary thyroid cancer--case report and review of the literatureGeeta Lal
Department of Surgery, University of California, San Francisco, UCSF/Mt. Zion Medical Center, San Francisco, California 94143, USA
Thyroid 13:601-5. 2003..The literature pertaining to the diagnosis and management of hypercoagulability states in patients with cancer, in general, and thyroid cancer, in particular, is reviewed...
