JANET ELIZABETH LAINHARTSummaryAffiliation: University of Utah Country: USA Publications
Research Grants
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Detail Information
Publications
Autism, regression, and the broader autism phenotypeJanet E Lainhart
Department of Psychiatry, University of Utah, Salt Lake City, UT 84108 1236, USA
Am J Med Genet 113:231-7. 2002..Environmental events, however, may act in an additive or "second-hit" fashion in individuals with a genetic vulnerability to autism...- Advances in autism neuroimaging research for the clinician and geneticistJanet E Lainhart
Utah Autism Research Program, University of Utah, 421 Wakara Way, Salt Lake City, UT 84108, USA
Am J Med Genet C Semin Med Genet 142:33-9. 2006..Currently, no method of brain imaging helps with diagnosis or treatment of idiopathic autism, but ongoing research aims to unravel the heterogeneity of autism and may provide future diagnostic tools that inform treatment... - Head circumference and height in autism: a study by the Collaborative Program of Excellence in AutismJanet E Lainhart
Department of Psychiatry, The Brain Institute at the University of Utah, Salt Lake City, Utah 84108, USA
Am J Med Genet A 140:2257-74. 2006..The wide distribution of head circumference in autism has major implications for genetic, neuroimaging, and other neurobiological research... 
Microstructural connectivity of the arcuate fasciculus in adolescents with high-functioning autismP Thomas Fletcher
School of Computing, University of Utah, Salt Lake City, UT, USA
Neuroimage 51:1117-25. 2010....- A retrospective fetal ultrasound study of brain size in autismKyle Hobbs
School of Medicine, University of Utah, Salt Lake City, Utah, USA
Biol Psychiatry 62:1048-55. 2007..Fetal head circumference (HC) and biparietal diameter (BPD) are highly correlated with fetal brain volume and are measured on fetal ultrasounds... - Intact emotion facilitation for nonsocial stimuli in autism: is amygdala impairment in autism specific for social information?Mikle South
Department of Psychology, University of Utah, Salt Lake City, Utah, USA
J Int Neuropsychol Soc 14:42-54. 2008.... - Are there enhanced MBP autoantibodies in autism?Jane E Libbey
Department of Neurology, University of Utah, 30 North 1900 East, 3R330 SOM, Salt Lake City, UT 84132 2305, USA
J Autism Dev Disord 38:324-32. 2008..Autoantibody responses against MBP are unlikely to play a pathogenic role in autism... - How relevant are GFAP autoantibodies in autism and Tourette Syndrome?Nikki J Kirkman
Department of Neurology, University of Utah, 30 North 1900 East, 3R330 SOM, Salt Lake City, UT 84132 2305, USA
J Autism Dev Disord 38:333-41. 2008..Autoantibody responses against GFAP are unlikely to play a pathogenic role in autism or Tourette Syndrome... - Associations between IQ, total and regional brain volumes, and demography in a large normative sample of healthy children and adolescentsNicholas Lange
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Dev Neuropsychol 35:296-317. 2010..The relations between total and regional brain volumes and IQ can best be discerned when additional variables known to be associated with IQ, especially parental education and other demographic measures, are considered concurrently... - Utility of the Gilliam Autism Rating Scale in research and clinical populationsMikle South
Department of Psychology, University of Utah, USA
J Autism Dev Disord 32:593-9. 2002..It is recommended that clinicians and researchers using or considering using the GARS for autism diagnosis or ratings of autism severity recognize the need for further research regarding its use... - Are there altered antibody responses to measles, mumps, or rubella viruses in autism?Jane E Libbey
Department of Neurology, University of Utah, Salt Lake City, Utah 84132 2305, USA
J Neurovirol 13:252-9. 2007.... - Temporal lobe, autism, and macrocephalyErin D Bigler
Department of Psychology and Neuroscience, Brigham Young University, Provo, UT, USA
AJNR Am J Neuroradiol 24:2066-76. 2003..Temporal lobe abnormalities that may be associated with autism are likely to be more related to functional organization within the temporal lobe than to any gross volumetric difference... 
Quantitative magnetic resonance image analysis of the cerebellum in macrocephalic and normocephalic children and adults with autismHoward B Cleavinger
Department of Psychology, Brigham Young University, Provo, Utah, USA
J Int Neuropsychol Soc 14:401-13. 2008..In autism, with and without macrocephaly, cerebellar structures were found to be proportional to head size and did not differ from typically developing subjects...- Macrocephaly, corpus callosum morphology, and autismSara A Rice
Department of Psychology and Neuroscience, Brigham Young University, Provo, UT 84602, USA
J Child Neurol 20:34-41. 2005..These findings suggest no unique difference in overall regional corpus callosum surface area in autism with macrocephaly... - Increased rate of head growth during infancy in autismJanet E Lainhart
JAMA 290:393-4. 2003 - Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autismJee Eun Lee
Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI, United States
Neurosci Lett 424:127-32. 2007..These results suggest that white matter microstructure in autism is abnormal in these temporal lobe regions, which is consistent with theories of aberrant brain connectivity in autism... - Diffusion tensor imaging of the corpus callosum in AutismAndrew L Alexander
Department of Medical Physics, University of Wisconsin, Madison, WI, USA
Neuroimage 34:61-73. 2007..These results suggest that the microstructure of the corpus callosum is affected in autism, which may be related to nonverbal cognitive performance... - MMPI-2 personality profiles of high-functioning adults with autism spectrum disordersSally Ozonoff
University of California, Davis, USA
Assessment 12:86-95. 2005..Future directions and implications for identifying adults in need of a specialized autism assessment are discussed... - Superior temporal gyrus, language function, and autismErin D Bigler
Departments of Psychology and Neuroscience, Brigham Young University, Provo, UT 84602, USA
Dev Neuropsychol 31:217-38. 2007..Taken together, these findings suggest a possible failure in left hemisphere lateralization of language function involving the STG in autism... - Comorbid psychiatric disorders in children with autism: interview development and rates of disordersOvsanna T Leyfer
Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY, USA
J Autism Dev Disord 36:849-61. 2006..The sample demonstrated a high prevalence of specific phobia, obsessive compulsive disorder, and ADHD. The rates of psychiatric disorder in autism are high and are associated with functional impairment... - Quantitative temporal lobe differences: autism distinguished from controls using classification and regression tree analysisE Shannon Neeley
Department of Statistics, Brigham Young University, Provo, UT 84602, USA
Brain Dev 29:389-99. 2007..Results are discussed in terms of pathological connectivity within the temporal lobe as it relates to autism... - Offering to share: how to put heads together in autism neuroimagingMatthew K Belmonte
Department of Human Development, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY 14853 4401, USA
J Autism Dev Disord 38:2-13. 2008..A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on...
Research Grants
- CORE--ASCERTAINMENTJanet Lainhart; Fiscal Year: 2002..Years 3-5.3 will be devoted to retesting and re-scanning subjects in the Imaging Component longitudinal study and data analysis. Issues related to use of human subjects, diverse samples, and data monitoring and safety are addressed...
- The Microstructural Basis of Abnormal Connectivity in AutismJANET ELIZABETH LAINHART; Fiscal Year: 2010..Understanding the brain- basis of deficits, disease course, and outcome in these individuals is critical for development of autism-specific treatments as well as secondary and tertiary preventive interventions. ..
- Atypical Late Neurodevelopment in Autism: A Longitudinal MRI and DTI StudyJANET ELIZABETH LAINHART; Fiscal Year: 2010..This collaborative group has been effectively and productively working together on this longitudinal study since 2002. ..
- Atypical Late Neurodevelopment in Autism: A Longitudinal MRI and DTI StudyJANET ELIZABETH LAINHART; Fiscal Year: 2011..This collaborative group has been effectively and productively working together on this longitudinal study since 2002. ..