Kristine Y Lain

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi Metabolic changes in pregnancy
    Kristine Y Lain
    Departments of Obstetrics and Gynecology and Internal Medicine, University of Kentucky, Lexington, Kentucky 40536 0293, USA
    Clin Obstet Gynecol 50:938-48. 2007
  2. ncbi Intracellular adhesion molecule concentrations in women who smoke during pregnancy
    Kristine Y Lain
    Magee Womens Research Institute and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Obstet Gynecol 107:588-94. 2006
  3. pmc Evidence of endothelial dysfunction in preeclampsia and risk of adverse pregnancy outcome
    Robert W Powers
    Magee Womens Research Institute, Pittsburgh, Pennsylvania 15213, USA
    Reprod Sci 15:374-81. 2008
  4. doi First trimester adipocytokine concentrations and risk of developing gestational diabetes later in pregnancy
    Kristine Y Lain
    Department of Obstetrics and Gynaecology, University of Kentucky, Lexington, KY 40536 0293, USA
    Clin Endocrinol (Oxf) 69:407-11. 2008
  5. ncbi Effect of smoking on uric acid and other metabolic markers throughout normal pregnancy
    Kristine Y Lain
    Magee Womens Research Institute and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 90:5743-6. 2005
  6. ncbi Uric acid is as important as proteinuria in identifying fetal risk in women with gestational hypertension
    James M Roberts
    Department of Obstetrics, Gynecology and Reproductive Sciences, Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 46:1263-9. 2005
  7. doi Extreme morbid obesity and labor outcome in nulliparous women at term
    Matthew J Garabedian
    Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky 40536, USA
    Am J Perinatol 28:729-34. 2011
  8. ncbi Preeclampsia activates circulating immune cells with engagement of the NF-kappaB pathway
    Patrizia Luppi
    Division of Immunogenetics, Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh, School of Medicine, PA 15213, USA
    Am J Reprod Immunol 56:135-44. 2006
  9. ncbi Smoking during pregnancy is associated with alterations in markers of endothelial function
    Kristine Y Lain
    Magee Womens Research Institute and Department of Obstetrics, Gynecology, and Reproductive Sciences, Pittsburgh, PA, USA
    Am J Obstet Gynecol 189:1196-201. 2003
  10. doi Neonatal adiposity following maternal treatment of gestational diabetes with glyburide compared with insulin
    Kristine Y Lain
    Department of Obstetrics and Gynecology, University of Kentucky College of Medicine, Lexington, KY 40536 0293, USA
    Am J Obstet Gynecol 200:501.e1-6. 2009

Detail Information

Publications14

  1. ncbi Metabolic changes in pregnancy
    Kristine Y Lain
    Departments of Obstetrics and Gynecology and Internal Medicine, University of Kentucky, Lexington, Kentucky 40536 0293, USA
    Clin Obstet Gynecol 50:938-48. 2007
    ..An increase in insulin resistance results in increases in maternal glucose and free fatty acid concentrations, allowing for greater substrate availability for fetal growth...
  2. ncbi Intracellular adhesion molecule concentrations in women who smoke during pregnancy
    Kristine Y Lain
    Magee Womens Research Institute and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Obstet Gynecol 107:588-94. 2006
    ..Our objectives were to determine if smoking has an impact on endothelial function in pregnancy by comparing markers of endothelial function and to evaluate the contribution from different cellular sources...
  3. pmc Evidence of endothelial dysfunction in preeclampsia and risk of adverse pregnancy outcome
    Robert W Powers
    Magee Womens Research Institute, Pittsburgh, Pennsylvania 15213, USA
    Reprod Sci 15:374-81. 2008
    ..5-13.1) in women with preeclampsia, hyperuricemia, and elevated cFN compared with normotensive women. Elevated cFN is prevalent among women with preeclampsia and identifies women at increased risk of preterm delivery and SGA...
  4. doi First trimester adipocytokine concentrations and risk of developing gestational diabetes later in pregnancy
    Kristine Y Lain
    Department of Obstetrics and Gynaecology, University of Kentucky, Lexington, KY 40536 0293, USA
    Clin Endocrinol (Oxf) 69:407-11. 2008
    ..Adipocytokines are important regulators of insulin resistance. The aim of this study was to compare maternal adipocytokines in early pregnancy among women diagnosed with and without gestational diabetes (GDM) months later...
  5. ncbi Effect of smoking on uric acid and other metabolic markers throughout normal pregnancy
    Kristine Y Lain
    Magee Womens Research Institute and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 90:5743-6. 2005
    ..We compared several metabolic markers of the metabolic syndrome in healthy primigravid smokers and nonsmokers over normal pregnancy to explore mechanisms for the reduced risk of preeclampsia in smokers...
  6. ncbi Uric acid is as important as proteinuria in identifying fetal risk in women with gestational hypertension
    James M Roberts
    Department of Obstetrics, Gynecology and Reproductive Sciences, Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 46:1263-9. 2005
    ..Hyperuricemia is at least as effective as proteinuria at identifying gestational hypertensive pregnancies at increased risk. Uric acid should be reexamined for clinical and research utility...
  7. doi Extreme morbid obesity and labor outcome in nulliparous women at term
    Matthew J Garabedian
    Department of Obstetrics and Gynecology, University of Kentucky, Lexington, Kentucky 40536, USA
    Am J Perinatol 28:729-34. 2011
    ..We speculate a qualitative or quantitative deficiency in the hormonal regulation of labor exists in the morbidly obese parturient. More research is needed to better understand the influence of morbid obesity on labor...
  8. ncbi Preeclampsia activates circulating immune cells with engagement of the NF-kappaB pathway
    Patrizia Luppi
    Division of Immunogenetics, Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh, School of Medicine, PA 15213, USA
    Am J Reprod Immunol 56:135-44. 2006
    ..Here, we investigated activation in additional leukocyte populations among women with preeclampsia...
  9. ncbi Smoking during pregnancy is associated with alterations in markers of endothelial function
    Kristine Y Lain
    Magee Womens Research Institute and Department of Obstetrics, Gynecology, and Reproductive Sciences, Pittsburgh, PA, USA
    Am J Obstet Gynecol 189:1196-201. 2003
    ..Alterations in endothelial function may explain the reduced risk of preeclampsia that is associated with smoking. We hypothesized that markers of endothelial function increase over pregnancy but decrease with smoking...
  10. doi Neonatal adiposity following maternal treatment of gestational diabetes with glyburide compared with insulin
    Kristine Y Lain
    Department of Obstetrics and Gynecology, University of Kentucky College of Medicine, Lexington, KY 40536 0293, USA
    Am J Obstet Gynecol 200:501.e1-6. 2009
    ..We hypothesized that body composition would be similar among neonates of women with gestational diabetes (GDM) treated with glyburide or insulin...
  11. doi Violence against women and postpartum depression
    Matthew J Garabedian
    Department of Obstetrics and Gynecology, University of Kentucky, 800 Rose Street, Lexington, KY 40536 0293, USA
    J Womens Health (Larchmt) 20:447-53. 2011
    ..We examined the association between these violence exposures and self-reported history of postpartum depression (PPD)...
  12. ncbi Second pregnancy outcomes following preeclampsia in a first pregnancy
    Kristine Y Lain
    Magee Womens Research Institute, Pittsburgh, PA 15213, USA
    Hypertens Pregnancy 24:159-69. 2005
    ..We compared second pregnancy outcomes among women with and without preeclampsia in their first pregnancies who all had second pregnancies without preeclampsia...
  13. ncbi Plasma homocysteine and malondialdehyde are correlated in an age- and gender-specific manner
    Robert W Powers
    Magee Womens Research Institute and Department of Obstetrics Gynecology and Reproductive Sciences, University of Pittsburgh, PA 15213, USA
    Metabolism 51:1433-8. 2002
    ..Since oxidative stress correlates with basal homocysteine only in young men and does not increase with acutely increased homocysteine, it is unlikely to be the result of a direct effect of homocysteine...
  14. ncbi The effects of cigarette smoking on circulating maternal leukocytes during pregnancy
    Patrizia Luppi
    Division of Immunogenetics, Department of Pediatrics, Rangos Research Center, Children s Hospital of Pittsburgh, PA 15213, USA
    Clin Immunol 122:214-9. 2007
    ..Our data demonstrate that smoking affects several immune parameters, especially early in pregnancy. These perturbations may play a role in pregnancy loss in women who smoke...