Chi Lai

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies
    M A St John
    Division of Head and Neck Surgery, Department of Surgery, David Geffen School of Medicine, UCLA, 10833 Le Conte Avenue, CHS 62 132, Los Angeles, CA 90095, USA
    Br J Cancer 107:707-12. 2012
  2. ncbi request reprint Recent new approaches to the treatment of head and neck cancer
    Maie A R St John
    School of Medicine, University of California, Los Angeles, California, USA
    Anticancer Drugs 17:365-75. 2006
  3. pmc Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma
    Maie A St John
    Division of Head and Neck Surgery, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Clin Cancer Res 15:6018-27. 2009
  4. doi request reprint The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC
    Mariam Dohadwala
    Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Otolaryngol Head Neck Surg 142:753-9. 2010
  5. doi request reprint Squamous cell carcinoma of buccal mucosa: a 40-year review
    Adam Deconde
    Division of Head and Neck Surgery, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Otolaryngol 33:673-7. 2012
  6. pmc Is there a role for neck dissection in T1 oral tongue squamous cell carcinoma? The UCLA experience
    Kevin A Peng
    Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave CHS 62 132, Los Angeles, CA
    Am J Otolaryngol 35:741-6. 2014
  7. pmc The CD44(high) tumorigenic subsets in lung cancer biospecimens are enriched for low miR-34a expression
    Saroj K Basak
    Wadsworth Stem Cell Institute, Veterans Affairs Greater Los Angeles Healthcare System VAGLAHS, Los Angeles, California, United States of America Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
    PLoS ONE 8:e73195. 2013
  8. ncbi request reprint Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
    Mariam Dohadwala
    Lung Cancer Research Program of the University of California at Los Angeles Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA
    Cancer Res 66:5338-45. 2006
  9. pmc Cystic adventitial disease of the popliteal artery: features on 3T cardiovascular magnetic resonance
    Anderanik Tomasian
    Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    J Cardiovasc Magn Reson 10:38. 2008
  10. doi request reprint Pediatric squamous cell carcinoma: Case report and literature review
    Douglas Sidell
    Department of Head and Neck Surgery, University of California Los Angeles Medical Center, USA
    Laryngoscope 119:1538-41. 2009

Collaborators

Detail Information

Publications18

  1. pmc Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies
    M A St John
    Division of Head and Neck Surgery, Department of Surgery, David Geffen School of Medicine, UCLA, 10833 Le Conte Avenue, CHS 62 132, Los Angeles, CA 90095, USA
    Br J Cancer 107:707-12. 2012
    ..These findings suggest that therapies targeting the cyclooxygenase pathway may diminish the propensity for tumour metastasis in HNSCC by blocking the PGE2-mediated induction of E-cadherin transcriptional repressors...
  2. ncbi request reprint Recent new approaches to the treatment of head and neck cancer
    Maie A R St John
    School of Medicine, University of California, Los Angeles, California, USA
    Anticancer Drugs 17:365-75. 2006
    ..Here, we review state-of-the-art therapy and presents selected advances in the treatment of head and neck cancer...
  3. pmc Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma
    Maie A St John
    Division of Head and Neck Surgery, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Clin Cancer Res 15:6018-27. 2009
    ..Herein we investigate the mechanisms by which interleukin-1beta (IL-1beta) might contribute to Epithelial-Mesenchymal Transition (EMT) in HNSCC...
  4. doi request reprint The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC
    Mariam Dohadwala
    Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Otolaryngol Head Neck Surg 142:753-9. 2010
    ..To determine the role of ZEB1 in the inflammation-induced promotion of the epithelial-mesenchymal transition (EMT) in head and neck squamous cell carcinoma (HNSCC)...
  5. doi request reprint Squamous cell carcinoma of buccal mucosa: a 40-year review
    Adam Deconde
    Division of Head and Neck Surgery, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Otolaryngol 33:673-7. 2012
    ..The aim of this study was to analyze the outcome of surgical therapy for buccal squamous cell carcinoma (SCCA) at a single tertiary care institution during a 40-year period...
  6. pmc Is there a role for neck dissection in T1 oral tongue squamous cell carcinoma? The UCLA experience
    Kevin A Peng
    Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave CHS 62 132, Los Angeles, CA
    Am J Otolaryngol 35:741-6. 2014
    ..We sought to examine prognostic and therapeutic implications, including cost-effectiveness, of elective neck dissection in the management of patients with clinically-determined T1N0 oral tongue carcinoma...
  7. pmc The CD44(high) tumorigenic subsets in lung cancer biospecimens are enriched for low miR-34a expression
    Saroj K Basak
    Wadsworth Stem Cell Institute, Veterans Affairs Greater Los Angeles Healthcare System VAGLAHS, Los Angeles, California, United States of America Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
    PLoS ONE 8:e73195. 2013
    ..In addition the highly tumorigenic CD44(hi) cells are enriched for cells in the G2 phase of cell cycle...
  8. ncbi request reprint Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
    Mariam Dohadwala
    Lung Cancer Research Program of the University of California at Los Angeles Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA
    Cancer Res 66:5338-45. 2006
    ..Thus, blocking PGE(2) production or activity may contribute to both prevention and treatment of NSCLC...
  9. pmc Cystic adventitial disease of the popliteal artery: features on 3T cardiovascular magnetic resonance
    Anderanik Tomasian
    Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    J Cardiovasc Magn Reson 10:38. 2008
    ..We report the case of a 26-year-old male with CAD of the right popliteal artery diagnosed non-invasively with 3 Tesla cardiovascular magnetic resonance and confirmed on post-operative histopathology...
  10. doi request reprint Pediatric squamous cell carcinoma: Case report and literature review
    Douglas Sidell
    Department of Head and Neck Surgery, University of California Los Angeles Medical Center, USA
    Laryngoscope 119:1538-41. 2009
    ..Describe a rare pediatric malignancy. Discuss the clinical, diagnostic, and therapeutic differences between squamous cell carcinoma (SCC) of the adult and pediatric population...
  11. ncbi request reprint Postoperative complications of lung transplantation: radiologic findings along a time continuum
    Mayil S Krishnam
    Department of Radiological Sciences, David Geffen School of Medicine, University of California at Los Angeles, Peter V Ueberroth Bldg, Suite 3371, 10945 LeConte Ave, Los Angeles, CA 90095 7206, USA
    Radiographics 27:957-74. 2007
    ....
  12. pmc Head and neck sarcomas: the UCLA experience
    Bobby A Tajudeen
    Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA UCLA Head and Neck Cancer Program, David Geffen School of Medicine at UCLA, Los Angeles, CA
    Am J Otolaryngol 35:476-81. 2014
    ..To profile the clinical presentation, subtype distribution, and treatment results of sarcomas of the head and neck at a single tertiary academic center over an 11-year period...
  13. pmc Sinonasal rhabdomyosarcoma: prognostic factors and treatment outcomes
    Christopher F Thompson
    Department of Head and Neck Surgery, University of California, Los Angeles, CA 90095 1624, USA
    Int Forum Allergy Rhinol 3:678-83. 2013
    ..Since few institutions have extensive experience with sinonasal rhabdomyosarcoma in children and adults, our objective was to determine prognostic factors and treatment outcomes for this rare malignancy...
  14. pmc Phosphorylated S6 kinase and S6 ribosomal protein are diagnostic markers of antibody-mediated rejection in heart allografts
    Fang Li
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles
    J Heart Lung Transplant 34:580-7. 2015
    ..We tested the hypothesis that phosphorylation of S6K, S6RP and ERK in capillary endothelium may serve as an adjunct diagnostic tool for antibody-mediated rejection (AMR) in heart allografts...
  15. doi request reprint Analysis of surgical margins in cases of mandibular osteoradionecrosis that progress despite extensive mandible resection and free tissue transfer
    Soroush Zaghi
    Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095 1624, USA
    Am J Otolaryngol 33:576-80. 2012
    ..Approximately 1 of 4 patients with osteoradionecrosis (ORN) of the mandible develop ongoing disease despite extensive mandible resection to margins determined by the presence of bleeding bone at the time of surgery...
  16. doi request reprint Parotidectomy and neck dissection in the management of conjunctival melanoma: are they necessary?
    Darshni Vira
    Department of Head and Neck Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA
    Laryngoscope 122:2436-41. 2012
    ..The objectives of this study were to review traditional techniques for the management of conjunctival melanoma and assess the need for parotidectomy and neck dissection in the management of conjunctival melanoma...
  17. doi request reprint Diverse morphologic manifestations of cardiac allograft vasculopathy: a pathologic study of 64 allograft hearts
    Wei hui Lü
    Department of Pathology and Laboratory Medicine, Division of Anatomic Pathology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA
    J Heart Lung Transplant 30:1044-50. 2011
    ..Although there are published descriptions of the lesions, there have been no studies delineating the pathology of CAV in a large series of patients who underwent retransplantation for CAV...
  18. ncbi request reprint Cardiac hemangioma: features on cardiovascular magnetic resonance
    Anderanik Tomasian
    Department of Radiological Sciences, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA
    J Cardiovasc Magn Reson 9:873-6. 2007
    ..We present a case of cardiac capillary hemangioma in a patient who presented with a history of recurrent episodes of syncope. Cardiovascular magnetic resonance played an important role in the diagnosis of cardiac hemangioma in our patient...