A C Lahti

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Functional effects of single dose first- and second-generation antipsychotic administration in subjects with schizophrenia
    Adrienne C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Psychiatry Res 139:19-30. 2005
  2. ncbi request reprint Clozapine but not haloperidol Re-establishes normal task-activated rCBF patterns in schizophrenia within the anterior cingulate cortex
    Adrienne C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 29:171-8. 2004
  3. ncbi request reprint Correlations between rCBF and symptoms in two independent cohorts of drug-free patients with schizophrenia
    Adrienne C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 31:221-30. 2006
  4. ncbi request reprint Abnormal patterns of regional cerebral blood flow in schizophrenia with primary negative symptoms during an effortful auditory recognition task
    A C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore 21228, USA
    Am J Psychiatry 158:1797-808. 2001
  5. ncbi request reprint Brain activation patterns in schizophrenic and comparison volunteers during a matched-performance auditory recognition task
    H H Holcomb
    Maryland Psychiatric Research Center, University of Maryland at Baltimore, 21228, USA
    Am J Psychiatry 157:1634-45. 2000
  6. ncbi request reprint Cerebral blood flow relationships associated with a difficult tone recognition task in trained normal volunteers
    H H Holcomb
    Maryland Psychiatric Research Center, Johns Hopkins Medical Institutes, Baltimore 21228 0247, USA
    Cereb Cortex 8:534-42. 1998
  7. ncbi request reprint The relationship between smooth pursuit eye movements and tardive dyskinesia in schizophrenia
    D E Ross
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland at Baltimore, MD, USA
    Schizophr Res 31:141-50. 1998
  8. ncbi request reprint Probing the human hippocampus using rCBF: contrasts in schizophrenia
    D R Medoff
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore 21228, USA
    Hippocampus 11:543-50. 2001
  9. ncbi request reprint Effects of ketamine in normal and schizophrenic volunteers
    A C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 25:455-67. 2001
  10. ncbi request reprint Sequential regional cerebral blood flow brain scans using PET with H2(15)O demonstrate ketamine actions in CNS dynamically
    H H Holcomb
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, UMAB, Baltimore, MD 21228, USA
    Neuropsychopharmacology 25:165-72. 2001

Detail Information

Publications21

  1. ncbi request reprint Functional effects of single dose first- and second-generation antipsychotic administration in subjects with schizophrenia
    Adrienne C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Psychiatry Res 139:19-30. 2005
    ..Differences in the involvement in basal ganglia parallel known differences between the drugs in the emergence of acute EPS upon emergency administration...
  2. ncbi request reprint Clozapine but not haloperidol Re-establishes normal task-activated rCBF patterns in schizophrenia within the anterior cingulate cortex
    Adrienne C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 29:171-8. 2004
    ..Based on these preliminary data, we propose that this pattern may account for the superior therapeutic effect of clozapine and represents a surrogate marker of this action...
  3. ncbi request reprint Correlations between rCBF and symptoms in two independent cohorts of drug-free patients with schizophrenia
    Adrienne C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 31:221-30. 2006
    ..The involvement of both frontal and parietal regions is implicated in the pathophysiology of negative symptoms...
  4. ncbi request reprint Abnormal patterns of regional cerebral blood flow in schizophrenia with primary negative symptoms during an effortful auditory recognition task
    A C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore 21228, USA
    Am J Psychiatry 158:1797-808. 2001
    ..Using functional brain imaging, the authors sought to replicate their earlier finding of low metabolism in the middle frontal and inferior parietal cortices of schizophrenic patients with primary negative symptoms...
  5. ncbi request reprint Brain activation patterns in schizophrenic and comparison volunteers during a matched-performance auditory recognition task
    H H Holcomb
    Maryland Psychiatric Research Center, University of Maryland at Baltimore, 21228, USA
    Am J Psychiatry 157:1634-45. 2000
    ..In this report, investigators used an auditory recognition task to assess brain blood flow patterns and behavioral correlates of schizophrenic patient volunteers trained on the task...
  6. ncbi request reprint Cerebral blood flow relationships associated with a difficult tone recognition task in trained normal volunteers
    H H Holcomb
    Maryland Psychiatric Research Center, Johns Hopkins Medical Institutes, Baltimore 21228 0247, USA
    Cereb Cortex 8:534-42. 1998
    ....
  7. ncbi request reprint The relationship between smooth pursuit eye movements and tardive dyskinesia in schizophrenia
    D E Ross
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland at Baltimore, MD, USA
    Schizophr Res 31:141-50. 1998
    ..To examine the relationship between smooth pursuit eye movements and tardive dyskinesia (TD) in schizophrenia...
  8. ncbi request reprint Probing the human hippocampus using rCBF: contrasts in schizophrenia
    D R Medoff
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore 21228, USA
    Hippocampus 11:543-50. 2001
    ..These data show an abnormality of hippocampal function in schizophrenia and suggest that this abnormality may be associated with the pathophysiology of the illness...
  9. ncbi request reprint Effects of ketamine in normal and schizophrenic volunteers
    A C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 25:455-67. 2001
    ..This study indicates that NVs could be used for many informative experimental psychosis studies involving ketamine interviews...
  10. ncbi request reprint Sequential regional cerebral blood flow brain scans using PET with H2(15)O demonstrate ketamine actions in CNS dynamically
    H H Holcomb
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, UMAB, Baltimore, MD 21228, USA
    Neuropsychopharmacology 25:165-72. 2001
    ..This experimental design provides direct characterization of drug action in the CNS in ways heretofore unavailable...
  11. ncbi request reprint Decisional capacity for informed consent in schizophrenia research
    W T Carpenter
    Maryland Psychiatric Research Center and the Department of Psychiatry, University of Maryland, Baltimore 21228, USA
    Arch Gen Psychiatry 57:533-8. 2000
    ....
  12. ncbi request reprint Long-term outcome of patients who receive ketamine during research
    A C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland 21228, USA
    Biol Psychiatry 49:869-75. 2001
    ..This study strongly indicates that administering ketamine does not change any aspect of the course of schizophrenic illness...
  13. ncbi request reprint Association between eye tracking disorder in schizophrenia and poor sensory integration
    D E Ross
    Department of Psychiatry, Maryland Psychiatric Research Center, University of Maryland at Baltimore, USA
    Am J Psychiatry 155:1352-7. 1998
    ..The authors tested the hypothesis that eye tracking disorder in schizophrenia is associated with neurological signs...
  14. ncbi request reprint Effects of noncompetitive NMDA receptor blockade on anterior cingulate cerebral blood flow in volunteers with schizophrenia
    Henry H Holcomb
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD 21228, USA
    Neuropsychopharmacology 30:2275-82. 2005
    ..The loss of inhibition and increased glutamate release may cause the distorted thoughts and diminished cognitive abilities elicited by NMDAR blockade...
  15. ncbi request reprint Subtle effects of ketamine on memory when administered following stimulus presentation
    David J LaPorte
    Department of Psychology, Indiana University of Pennsylvania, Uhler Hall, Indiana, PA 15705 1068, USA
    Psychopharmacology (Berl) 180:385-90. 2005
    ....
  16. ncbi request reprint Parametric study of accuracy and response time in schizophrenic persons making visual or auditory discriminations
    Henry H Holcomb
    Maryland Psychiatric Research Center, P O Box 21247, Baltimore, MD 21228, USA
    Psychiatry Res 127:207-16. 2004
    ..The schizophrenia group's tendency to process high and low error conditions with similar behavioral resources may reflect a relatively static, non-dynamic cognitive repertoire...
  17. ncbi request reprint Evaluating glutamatergic transmission in schizophrenia
    Carol A Tamminga
    University of Texas Southwestern Medical School, Dallas, Texas, 75390, USA
    Ann N Y Acad Sci 1003:113-8. 2003
    ..What I will report in this paper has been individually reported elsewhere but brought together here in a new synthesis...
  18. ncbi request reprint Schizophrenia, VIII: pharmacologic models
    Adrienne C Lahti
    UT Southwestern Medical Center, Department of Psychiatry, 5323 Harry Hines Blvd, NC5 914, Dallas, TX 75390 9070, USA
    Am J Psychiatry 160:2091. 2003
  19. ncbi request reprint Functional effects of antipsychotic drugs: comparing clozapine with haloperidol
    Adrienne C Lahti
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland 21228, USA
    Biol Psychiatry 53:601-8. 2003
    ....
  20. ncbi request reprint Effects of ketamine on leading saccades during smooth-pursuit eye movements may implicate cerebellar dysfunction in schizophrenia
    Matthew T Avila
    Maryland Psychiatric Research Center, Baltimore 21228, USA
    Am J Psychiatry 159:1490-6. 2002
    ..The authors examined the effects of ketamine on leading saccadic eye movements, a specific component of the smooth-pursuit response shown to be abnormal in schizophrenia patients and their relatives...
  21. ncbi request reprint The effects of a subanesthetic dose of ketamine on verbal memory in normal volunteers
    Arti Parwani
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, P O Box 21247, Baltimore, MD 21228, USA
    Psychopharmacology (Berl) 183:265-74. 2005
    ....