Asenath La Rue
Affiliation: University of Wisconsin
- Effect of parental family history of Alzheimer's disease on serial position profilesAsenath La Rue
Wisconsin Alzheimer s Institute, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Alzheimers Dement 4:285-90. 2008..Our study sought to determine whether there were similar alterations in serial position learning among asymptomatic persons at risk for AD as a result of parental family history...
- Healthy brain aging: role of cognitive reserve, cognitive stimulation, and cognitive exercisesAsenath La Rue
Wisconsin Alzheimer s Institute, School of Medicine and Public Health, University of Wisconsin Madison, 7818 Big Sky Drive, Suite 215, Madison, WI 53719, USA
Clin Geriatr Med 26:99-111. 2010..More randomized controlled trials, using challenging regimes of training and stimulation and long-term follow-up, are needed, measuring cognitive trajectories in normal aging and relative risk of Alzheimer disease as outcomes...
- Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adultsAuriel A Willette
Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, WI, USA
Diabetes Care 36:443-9. 2013..This longitudinal study examined whether insulin resistance among late middle-aged, cognitively healthy individuals was associated with 1) less gray matter in Alzheimer disease-sensitive brain regions and 2) worse cognitive performance...
- Machine learning amplifies the effect of parental family history of Alzheimer's disease on list learning strategyTimothy S Chang
Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
J Int Neuropsychol Soc 18:428-39. 2012..The results of our machine learning approach support analyzing memory strategy in detail to probe potential disease onset. Such distinct differences may be exploited in asymptomatic middle-aged persons as a potential risk factor for AD...
- The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotypeSterling C Johnson
Wisconsin Alzheimer s Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Alzheimers Dement 7:456-65. 2011..In this study, we tested the hypothesis that brain and cognitive changes suggestive of presymptomatic LOAD may be associated with this TOMM40 polymorphism...
- Interaction between two cholesterol metabolism genes influences memory: findings from the wisconsin registry for Alzheimer's preventionCorinne D Engelman
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
J Alzheimers Dis 36:749-57. 2013..01). Both of these genes are in the cholesterol metabolism pathway leading to AD. This research supports the importance of considering non-additive effects of AD susceptibility genes. ..
- Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer's PreventionMark A Sager
Wisconsin Alzheimer s Institute, Department of Medicine, University of Wisconsin Madison, 53719, USA
J Geriatr Psychiatry Neurol 18:245-9. 2005..The WRAP cohort may be a valuable group to follow prospectively to characterize the nature of cognitive change in relation to risk factors and to identify underlying preclinical neurobiological changes...
- Latent structure and factorial invariance of a neuropsychological test battery for the study of preclinical Alzheimer's diseaseN Maritza Dowling
Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, K6 446 Box 4675, J5 M194, Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792 4675, USA
Neuropsychology 24:742-56. 2010....
- Screening for dementia in community-based memory clinicsMark A Sager
Wisconsin Alzheimer s Institute, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53719, USA
WMJ 105:25-9. 2006..This study examined the usefulness of 3 brief screening tests in detecting dementia and mild cognitive impairment (MCI) in persons seeking consultation for memory complaints within a network of memory diagnostic clinics in Wisconsin...