Bonnie Ky

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Biomarker approach to the detection and cardioprotective strategies during anthracycline chemotherapy
    Bonnie Ky
    Division of Cardiovascular Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Heart Fail Clin 7:323-31. 2011
  2. ncbi Left ventricular remodeling in human heart failure: quantitative echocardiographic assessment of 1,794 patients
    Bonnie Ky
    Division of Cardiovascular Medicine Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Echocardiography 29:758-65. 2012
  3. ncbi Multiple biomarkers for risk prediction in chronic heart failure
    Bonnie Ky
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Circ Heart Fail 5:183-90. 2012
  4. ncbi The vascular marker soluble fms-like tyrosine kinase 1 is associated with disease severity and adverse outcomes in chronic heart failure
    Bonnie Ky
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Am Coll Cardiol 58:386-94. 2011
  5. ncbi High-sensitivity ST2 for prediction of adverse outcomes in chronic heart failure
    Bonnie Ky
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Circ Heart Fail 4:180-7. 2011
  6. ncbi Gender differences in cardiac remodeling and clinical outcomes in chronic stable angina pectoris (from the ACTION Trial)
    Bonnie Ky
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Cardiol 105:943-7. 2010
  7. ncbi The effects of statin therapy on plasma markers of inflammation in patients without vascular disease
    Bonnie Ky
    University of Pennsylvania Medical Center, Division of Cardiovascular Medicine, Philadelphia, Pennsylvania 19104 6160, USA
    Clin Cardiol 28:67-70. 2005
  8. ncbi Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure
    Bonnie Ky
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Circulation 120:310-7. 2009
  9. ncbi Simultaneous assessment of unprocessed ProBNP1-108 in addition to processed BNP32 improves identification of high-risk ambulatory patients with heart failure
    Daniel L Dries
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA PA 19104, USA
    Circ Heart Fail 3:220-7. 2010
  10. ncbi Clinical utility of automated assessment of left ventricular ejection fraction using artificial intelligence-assisted border detection
    Hind W Rahmouni
    Department of Medicine, Cardiovascular Division, University of Pennsylvania, School of Medicine, Philadelphia, PA, USA
    Am Heart J 155:562-70. 2008

Detail Information

Publications19

  1. ncbi Biomarker approach to the detection and cardioprotective strategies during anthracycline chemotherapy
    Bonnie Ky
    Division of Cardiovascular Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Heart Fail Clin 7:323-31. 2011
    ..This review highlights the current evidence regarding the use of biomarkers in anthracycline-treated patients and presents the available literature on prophylactic cardioprotective strategies...
  2. ncbi Left ventricular remodeling in human heart failure: quantitative echocardiographic assessment of 1,794 patients
    Bonnie Ky
    Division of Cardiovascular Medicine Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Echocardiography 29:758-65. 2012
    ..We sought to define the adaptive remodeling that occurs in chronic human HF through the detailed analyses of a large quantitative echocardiography database...
  3. ncbi Multiple biomarkers for risk prediction in chronic heart failure
    Bonnie Ky
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Circ Heart Fail 5:183-90. 2012
    ..Prior studies have suggested using a panel of biomarkers that measure diverse biological processes as a prognostic tool in chronic heart failure. Whether this approach improves risk prediction beyond clinical evaluation is unknown...
  4. ncbi The vascular marker soluble fms-like tyrosine kinase 1 is associated with disease severity and adverse outcomes in chronic heart failure
    Bonnie Ky
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Am Coll Cardiol 58:386-94. 2011
    ..We sought to evaluate placental growth factor (PlGF) and soluble Fms-like tyrosine kinase 1 (sFlt-1) as clinical biomarkers in chronic heart failure (HF)...
  5. ncbi High-sensitivity ST2 for prediction of adverse outcomes in chronic heart failure
    Bonnie Ky
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Circ Heart Fail 4:180-7. 2011
    ..The use of ST2 in chronic heart failure has not been well defined. Our objective was to determine whether plasma ST2 levels predict adverse outcomes in chronic heart failure in the context of current approaches...
  6. ncbi Gender differences in cardiac remodeling and clinical outcomes in chronic stable angina pectoris (from the ACTION Trial)
    Bonnie Ky
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Cardiol 105:943-7. 2010
    ..These findings may reflect inherent gender-based differences in ischemic heart disease and cardiac remodeling and might help to identify women at high risk...
  7. ncbi The effects of statin therapy on plasma markers of inflammation in patients without vascular disease
    Bonnie Ky
    University of Pennsylvania Medical Center, Division of Cardiovascular Medicine, Philadelphia, Pennsylvania 19104 6160, USA
    Clin Cardiol 28:67-70. 2005
    ..This article will review the relationship between inflammatory markers and cardiovascular disease risk and the effects of statins on these markers in subjects without a known history of coronary disease...
  8. ncbi Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure
    Bonnie Ky
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Circulation 120:310-7. 2009
    ..However, circulating NRG-1 has not been studied in human heart disease. We used a novel immunoassay to test whether circulating NRG-1beta is associated with disease severity and clinical outcomes in chronic heart failure...
  9. ncbi Simultaneous assessment of unprocessed ProBNP1-108 in addition to processed BNP32 improves identification of high-risk ambulatory patients with heart failure
    Daniel L Dries
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA PA 19104, USA
    Circ Heart Fail 3:220-7. 2010
    ..We hypothesized that simultaneous assessment of proBNP(1-108) and active BNP32, as an index of natriuretic peptide processing efficiency, would improve risk stratification in patients with chronic systolic heart failure...
  10. ncbi Clinical utility of automated assessment of left ventricular ejection fraction using artificial intelligence-assisted border detection
    Hind W Rahmouni
    Department of Medicine, Cardiovascular Division, University of Pennsylvania, School of Medicine, Philadelphia, PA, USA
    Am Heart J 155:562-70. 2008
    ..We tested Siemens AutoEF software (Siemens Medical Solutions, Erlangen, Germany) to determine whether it correlated with visual estimates of EF, manual planimetry, and cardiac magnetic resonance (CMR)...
  11. ncbi Short-term treatment with high-dose atorvastatin reduces LDL cholesterol but shows no anti-inflammatory effects in normolipidemic subjects with normal CRP levels
    John S Millar
    The Institute for Translational Medicine and Therapeutics, The University of Pennsylvania, Philadelphia, USA
    Clin Transl Sci 3:140-6. 2010
    ....
  12. ncbi Application of appropriateness criteria in outpatient transthoracic echocardiography
    James N Kirkpatrick
    Department of Medicine, Cardiovascular Division, Echocardiography Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Soc Echocardiogr 22:53-9. 2009
    ..Appropriateness criteria were applied to outpatient transthoracic echocardiographic (TTE) studies...
  13. ncbi The utility of prescreening transesophageal echocardiograms: a prospective study
    Jeffrey Ogbara
    Department of Medicine, Cardiovascular Division, Echocardiography Laboratory University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Echocardiography 28:767-73. 2011
    ..However, the intersection of the AUC with the safety and clinical use of transesophageal echocardiography (TEE) is not well established...
  14. ncbi Hand-carried echocardiography for assessment of left ventricular filling and ejection fraction in the surgical intensive care unit
    Dustin G Mark
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    J Crit Care 24:470.e1-7. 2009
    ....
  15. ncbi Transthoracic and transesophageal echocardiography for the indication of suspected infective endocarditis: vegetations, blood cultures and imaging
    Vinay Kini
    Hospital of the University of Pennsylvania, Department of Medicine, Cardiovascular Division, Philadelphia, Pennsylvania, USA
    J Am Soc Echocardiogr 23:396-402. 2010
    ..The aim of this study was to investigate the ability of transthoracic echocardiography (TTE) to detect vegetations and the relationship between blood cultures and transesophageal echocardiography (TEE)...
  16. ncbi Heart failure associated with sunitinib: lessons learned from animal models
    Colin F Greineder
    Department of Pharmacology, Institute for Translational Medicine and Therapeutics, Department of Emergency Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Curr Hypertens Rep 13:436-41. 2011
    ....
  17. ncbi The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans
    Bonnie Ky
    Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6160, USA
    J Am Coll Cardiol 51:1653-62. 2008
    ..The aim of this study was to determine the effects of pravastatin and atorvastatin on markers of oxidative stress in plasma...
  18. ncbi Common variants in HSPB7 and FRMD4B associated with advanced heart failure
    Thomas P Cappola
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, USA
    Circ Cardiovasc Genet 3:147-54. 2010
    ..We tested the hypothesis that inherited variation in genes of known importance to cardiovascular biology would thus contribute to heart failure risk...
  19. ncbi Differentiation syndrome in non-M3 acute myeloid leukemia treated with the retinoid X receptor agonist bexarotene
    Courtney D DiNardo
    Department of Internal Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Med Oncol 25:299-302. 2008
    ..This case emphasizes the importance of monitoring for differentiation syndrome among patients receiving retinoid therapies and demonstrates the ability of bexarotene to stimulate differentiation of leukemic blasts...