Jane Kuypers

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi Detection and quantification of human metapneumovirus in pediatric specimens by real-time RT-PCR
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, CHRMC, 4800 Sand Point Way N E, Virology Office, G 815, 8G 3, Seattle, WA 98105, USA
    J Clin Virol 33:299-305. 2005
  2. pmc Real-time reverse transcription-PCR assay for comprehensive detection of human rhinoviruses
    Xiaoyan Lu
    Gastroenteritis and Respiratory Virus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 46:533-9. 2008
  3. ncbi Clinical disease in children associated with newly described coronavirus subtypes
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Pediatrics 119:e70-6. 2007
  4. ncbi Evaluation of quantitative and type-specific real-time RT-PCR assays for detection of respiratory syncytial virus in respiratory specimens from children
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, CHRMC, 4800 Sand Point Way N E, Virology Office, G 815, 8G 3, Seattle, WA 98105, USA
    J Clin Virol 31:123-9. 2004
  5. pmc Comparison of real-time PCR assays with fluorescent-antibody assays for diagnosis of respiratory virus infections in children
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, 4800 Sand Point Way NE, Room W8814, Seattle, WA 98105, USA
    J Clin Microbiol 44:2382-8. 2006
  6. pmc Mortality rates of human metapneumovirus and respiratory syncytial virus lower respiratory tract infections in hematopoietic cell transplantation recipients
    Christian Renaud
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Biol Blood Marrow Transplant 19:1220-6. 2013
  7. pmc Respiratory virus pneumonia after hematopoietic cell transplantation (HCT): associations between viral load in bronchoalveolar lavage samples, viral RNA detection in serum samples, and clinical outcomes of HCT
    Angela P Campbell
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    J Infect Dis 201:1404-13. 2010
  8. pmc Self-collection of foam nasal swabs for respiratory virus detection by PCR among immunocompetent subjects and hematopoietic cell transplant recipients
    Angela P Campbell
    University of Washington, Seattle, Washington, USA
    J Clin Microbiol 51:324-7. 2013
  9. pmc Respiratory virus infection among hematopoietic cell transplant recipients: evidence for asymptomatic parainfluenza virus infection
    Angela J Peck
    Department of Pediatrics, Children s Hospital and Regional Medical Center and University of Washington, Seattle, WA, USA
    Blood 110:1681-8. 2007
  10. pmc WU and KI polyomaviruses in respiratory samples from allogeneic hematopoietic cell transplant recipients
    Jane Kuypers
    University of Washington, Seattle, Washington 98102, USA
    Emerg Infect Dis 18:1580-8. 2012

Collaborators

Detail Information

Publications34

  1. ncbi Detection and quantification of human metapneumovirus in pediatric specimens by real-time RT-PCR
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, CHRMC, 4800 Sand Point Way N E, Virology Office, G 815, 8G 3, Seattle, WA 98105, USA
    J Clin Virol 33:299-305. 2005
    ..Human metapneumovirus (h MPV), a recently identified virus, causes respiratory illness in children...
  2. pmc Real-time reverse transcription-PCR assay for comprehensive detection of human rhinoviruses
    Xiaoyan Lu
    Gastroenteritis and Respiratory Virus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 46:533-9. 2008
    ..The assay was successfully applied in an investigation of a coincidental outbreak of HRV respiratory illness among laboratory staff...
  3. ncbi Clinical disease in children associated with newly described coronavirus subtypes
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Pediatrics 119:e70-6. 2007
    ..In this study we examined the prevalence of 4 human coronaviruses, including subtypes OC43, 229E, and the recently described NL63 and HKU1 in a pediatric population presenting to a children's hospital...
  4. ncbi Evaluation of quantitative and type-specific real-time RT-PCR assays for detection of respiratory syncytial virus in respiratory specimens from children
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, CHRMC, 4800 Sand Point Way N E, Virology Office, G 815, 8G 3, Seattle, WA 98105, USA
    J Clin Virol 31:123-9. 2004
    ..Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract morbidity in young children and immunosuppressed patients...
  5. pmc Comparison of real-time PCR assays with fluorescent-antibody assays for diagnosis of respiratory virus infections in children
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, 4800 Sand Point Way NE, Room W8814, Seattle, WA 98105, USA
    J Clin Microbiol 44:2382-8. 2006
    ..Use of real-time PCR to identify viral respiratory pathogens in children will lead to improved diagnosis of respiratory illness...
  6. pmc Mortality rates of human metapneumovirus and respiratory syncytial virus lower respiratory tract infections in hematopoietic cell transplantation recipients
    Christian Renaud
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Biol Blood Marrow Transplant 19:1220-6. 2013
    ..Thus, HMPV lower respiratory tract disease is associated with high mortality in HCT recipients. Earlier detection in combination with new antiviral therapy is needed to reduce mortality among HCT recipients. ..
  7. pmc Respiratory virus pneumonia after hematopoietic cell transplantation (HCT): associations between viral load in bronchoalveolar lavage samples, viral RNA detection in serum samples, and clinical outcomes of HCT
    Angela P Campbell
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    J Infect Dis 201:1404-13. 2010
    ..Few data exist on respiratory virus quantitation in lower respiratory samples and detection in serum from hematopoietic cell transplant (HCT) recipients with respiratory virus-associated pneumonia...
  8. pmc Self-collection of foam nasal swabs for respiratory virus detection by PCR among immunocompetent subjects and hematopoietic cell transplant recipients
    Angela P Campbell
    University of Washington, Seattle, Washington, USA
    J Clin Microbiol 51:324-7. 2013
    ..004), respectively, and those from 140 URI samples from hematopoietic cell transplantation recipients were 88% and 85% (P = 0.56), respectively...
  9. pmc Respiratory virus infection among hematopoietic cell transplant recipients: evidence for asymptomatic parainfluenza virus infection
    Angela J Peck
    Department of Pediatrics, Children s Hospital and Regional Medical Center and University of Washington, Seattle, WA, USA
    Blood 110:1681-8. 2007
    ..004). Subclinical infection with PIV may help explain why infection-control programs that emphasize symptoms are effective against RSV and influenza but often not against PIV...
  10. pmc WU and KI polyomaviruses in respiratory samples from allogeneic hematopoietic cell transplant recipients
    Jane Kuypers
    University of Washington, Seattle, Washington 98102, USA
    Emerg Infect Dis 18:1580-8. 2012
    ..There were no associations with polyomavirus detection and acute graft versus host disease, cytomegalovirus reactivation, neutropenia, lymphopenia, hospitalization, or death...
  11. pmc Molecular epidemiology of respiratory syncytial virus transmission in childcare
    Helen Y Chu
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Clin Virol 57:343-50. 2013
    ..No prior studies using molecular techniques to examine RSV transmission in the community childcare setting have been performed...
  12. pmc Multiple viral respiratory pathogens in children with bronchiolitis
    Hilary E Stempel
    Seattle Children s Hospital Research Institute, University of Washington, Seattle, WA, USA
    Acta Paediatr 98:123-6. 2009
    ..The aim of the study was to describe the frequency of viral pathogens and relative frequency of co-infections in nasal specimens obtained from young children with bronchiolitis receiving care at a children's hospital...
  13. pmc Human rhinovirus and coronavirus detection among allogeneic hematopoietic stem cell transplantation recipients
    Filippo Milano
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Blood 115:2088-94. 2010
    ..HRV and HCoV infections are common in the first 100 days after HCT, viral shedding lasts more than 3 weeks in half, and lower respiratory infection is rare...
  14. pmc Comparison of the Simplexa FluA/B & RSV direct assay and laboratory-developed real-time PCR assays for detection of respiratory virus
    Mitchell W Woodberry
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, USA
    J Clin Microbiol 51:3883-5. 2013
    ..Concordance rates were 96.6% (476/493; κ = 0.91), 97.6% (481/493; κ = 0.47), and 99.2% (488/492; κ = 0.94) for influenza A, influenza B, and respiratory syncytial virus, respectively. ..
  15. ncbi Respiratory syncytial virus in hematopoietic cell transplant recipients: factors determining progression to lower respiratory tract disease
    Yae Jean Kim
    Fred Hutchinson Cancer Research Center, Seattle, Washington
    J Infect Dis 209:1195-204. 2014
    ..Lymphopenia has been associated with an increased risk of progression from upper respiratory tract infection (URI) to LRD...
  16. pmc Influenza viral RNA detection in blood as a marker to predict disease severity in hematopoietic cell transplant recipients
    Su Mi Choi
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Infect Dis 206:1872-7. 2012
    ..Among patients with LRD, viremia was associated with increased hazards of overall and influenza-associated death (hazard ratio 3.5, 1.1-12). Thus, influenza viremia may serve as marker for overall poor outcome...
  17. pmc Detection of adeno-associated virus viremia in hematopoietic cell transplant recipients
    Judson Heugel
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    J Infect Dis 204:1746-9. 2011
    ..Thus, AAV does not appear to play a pathogenic role in organ-specific illness, even in a highly immunocompromised population...
  18. doi Clinical disease and viral load in children infected with respiratory syncytial virus or human metapneumovirus
    Emily T Martin
    Children s Hospital and Regional Medical Center, Seattle, WA 98105, USA
    Diagn Microbiol Infect Dis 62:382-8. 2008
    ..Our study has described a significant relationship between viral load and markers of disease severity for both RSV and hMPV in a large population of children evaluated for respiratory disease...
  19. pmc Comparison of a multiplex real-time PCR assay with a multiplex Luminex assay for influenza virus detection
    Sandra B Munro
    Molecular Virology Laboratory, Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    J Clin Microbiol 51:1124-9. 2013
    ..The FLULUM is an economic assay with high clinical sensitivity and specificity. It is particularly suited to high-volume detection of influenza viruses...
  20. ncbi Coronavirus-associated pneumonia in previously healthy children
    Judson Heugel
    Department of Pediatrics, University of Washington and Children s Hospital and Regional Medical Center, Seattle, WA, USA
    Pediatr Infect Dis J 26:753-5. 2007
    ..Here, we document the clinical courses of 2 previously healthy children with coronavirus-associated pneumonia...
  21. ncbi Randomized controlled multicenter trial of aerosolized ribavirin for respiratory syncytial virus upper respiratory tract infection in hematopoietic cell transplant recipients
    Michael Boeckh
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Clin Infect Dis 44:245-9. 2007
    ..Respiratory syncytial virus infection of the upper airways may progress to fatal pneumonia in hematopoietic cell transplant recipients. The safety and efficacy of aerosolized ribavirin in preventing disease progression is unknown...
  22. pmc H275Y mutant pandemic (H1N1) 2009 virus in immunocompromised patients
    Christian Renaud
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Emerg Infect Dis 17:653-60; quiz 765. 2011
    ..Emergence of oseltamivir resistance is frequent in immunocompromised patients infected with pandemic (H1N1) 2009 virus and can be associated with a wide range of clinical disease and viral kinetics...
  23. ncbi Nosocomial transmission of respiratory syncytial virus in an outpatient cancer center
    Helen Y Chu
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington Electronic address
    Biol Blood Marrow Transplant 20:844-51. 2014
    ..Infection control interventions should be implemented in outpatient, as well as inpatient, settings to reduce person-to-person transmission and limit progression of RSV outbreaks. ..
  24. doi Comparison of FilmArray Respiratory Panel and laboratory-developed real-time reverse transcription-polymerase chain reaction assays for respiratory virus detection
    Christian Renaud
    Molecular Virology Laboratory, Department of Laboratory Medicine, University of Washington, Seattle, WA 98102, USA
    Diagn Microbiol Infect Dis 74:379-83. 2012
    ..While the FilmArray was rapid and easy to use, its low throughput and qualitative results may be a disadvantage in some clinical settings...
  25. pmc Frequent and prolonged shedding of bocavirus in young children attending daycare
    Emily T Martin
    Center for Clinical and Translational Research, Seattle Children s Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA
    J Infect Dis 201:1625-32. 2010
    ..Little is known about human bocavirus (HBoV) persistence and shedding and the association between HBoV detection and the onset and resolution of respiratory symptoms...
  26. ncbi Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipients
    Janet A Englund
    Children s Hospital and Regional Medical Center, University of Washington, and Fred Hutchinson Cancer Research Center, Seattle, Washington 98105, USA
    Ann Intern Med 144:344-9. 2006
    ..Human metapneumovirus (hMPV), a recently discovered respiratory virus, is associated with clinical disease in young and elderly persons...
  27. pmc Detection of bocavirus in saliva of children with and without respiratory illness
    Emily T Martin
    Center for Clinical and Translational Research, Seattle Children s Research Institute, Washington 98101, USA
    J Clin Microbiol 47:4131-2. 2009
    ..hBoV was detected in saliva samples at asymptomatic enrollment in 3% (5/149) and during respiratory illness in 2% (2/106) of the cases. hBoV was detected in only 1/149 asymptomatic and 0/106 illness nasal samples...
  28. doi Emerging oseltamivir resistance in seasonal and pandemic influenza A/H1N1
    Christian Renaud
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Clin Virol 52:70-8. 2011
    ..However, immunocompromised patients infected with oseltamivir-resistant H1N1 experience potentially more risks of complication and transmissibility with few therapeutic options...
  29. doi Emergence of oseltamivir-resistant pandemic H1N1 in an immunocompetent child with severe status asthmaticus
    Christian Renaud
    Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Asthma 48:572-5. 2011
    ..Pandemic influenza A (H1N1) may cause severe illness in pediatric patient with chronic lung disease...
  30. ncbi Acquisition and natural history of human papillomavirus type 16 variant infection among a cohort of female university students
    Long Fu Xi
    Department of Pathology, School of Medicine, University of Washington, Seattle, Washington 98103, USA
    Cancer Epidemiol Biomarkers Prev 11:343-51. 2002
    ....
  31. ncbi Liquid-based Papanicolaou smears without a transformation zone component: should clinicians worry?
    Atar Baer
    Department of Epidemiology, University of Washington, Seattle, Washington 98103, USA
    Obstet Gynecol 99:1053-9. 2002
    ..To evaluate whether ThinPrep smears without versus those with a transformation zone component were more likely to have falsely negative cytology findings...
  32. ncbi Characterization of IgA response among women with incident HPV 16 infection
    Takashi Onda
    Program in Cancer Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Virology 312:213-21. 2003
    ..6 months for serum IgA, whereas approximately 20% of women with serum IgG antibodies reverted within 36 months. Thus, the duration of IgA in cervical secretions and sera was shorter than the duration of serum IgG (P = 0.007 and 0.001)...
  33. ncbi Clinical findings among young women with genital human papillomavirus infection
    Constance Mao
    Department of Obstetrics and Gynecology, University of Washington, Seattle, USA
    Am J Obstet Gynecol 188:677-84. 2003
    ..The purpose of this study was to identify clinical signs and symptoms associated with detection of human papillomavirus (HPV) DNA in the female genital tract...
  34. ncbi Stability of archived liquid-based cervical cytologic specimens
    Philip E Castle
    The National Cancer Institute, Division of Cancer Epidemiology and Genetics, Rockville, Maryland 20892 7234, USA
    Cancer 99:89-96. 2003
    ..However, long-term DNA stability and cytologic stability of these biospecimens have not been evaluated...