Research Topics
| NATHAN contact KUPPERMANNSummaryAffiliation: University of California Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Risks for bacteremia and urinary tract infections in young febrile children with bronchiolitisN Kuppermann
Arch Pediatr Adolesc Med 151:1207-14. 1997..To compare the risks for bacteremia and urinary tract injections (UTI) in young febrile children with and without bronchiolitis...
Intracranial injury in minor head traumaN Kuppermann
Division of Emergency Medicine, UC Davis Medical Center, 2315 Stockton Blvd, PSSB Bldg, Suite 2100, Sacramento, CA 98517, USA
Arch Dis Child 89:593-4. 2004
Prolonged QT interval corrected for heart rate during diabetic ketoacidosis in childrenNathan Kuppermann
Department of Emergency Medicine, University of California, Davis, School of Medicine, 2315 Stockton Blvd, PSSB Bldg, Ste 2100, Sacramento, CA 95817, USA
Arch Pediatr Adolesc Med 162:544-9. 2008..Prolongation of the QTc has been described in a few children receiving ketogenic diets, but cardiac effects of ketosis have not otherwise been investigated...- Pediatric head trauma: the evidence regarding indications for emergent neuroimagingNathan Kuppermann
Department of Emergency Medicine, UC Davis Medical Center, Sacramento, CA 95817, USA
Pediatr Radiol 38:S670-4. 2008..These studies should provide the foundation of evidence to guide CT decisions by clinicians, help identify TBIs in a timely fashion, and reduce unnecessary radiation exposure... - Respiratory syncytial virus infection and the risk of serious bacterial infectionsNathan Kuppermann
Departments of Pediatrics and Internal Medicine, University of California-Davis School of Medicine, 2315 Stockton Blvd, PSSB, Suite 2100, Sacramento, CA 95817, USA
Arch Pediatr Adolesc Med 156:1055-6; author reply 1056-7. 2002 - Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort studyNathan Kuppermann
Department of Emergency Medicine, University of California, Davis School of Medicine, Davis, CA, USA
Lancet 374:1160-70. 2009..CT imaging of head-injured children has risks of radiation-induced malignancy. Our aim was to identify children at very low risk of clinically-important traumatic brain injuries (ciTBI) for whom CT might be unnecessary... - Predictors of intussusception in young childrenN Kuppermann
Department of Pediatrics, University of California, Davis School of Medicine, Sacramento 95817, USA
Arch Pediatr Adolesc Med 154:250-5. 2000..To identify predictors of intussusception in young children... - Immature neutrophils in the blood smears of young febrile childrenN Kuppermann
Department of Pediatrics, University of California, Davis, School of Medicine, USA
Arch Pediatr Adolesc Med 153:261-6. 1999..To determine whether the immature neutrophil (band) count in the peripheral blood smear helps to distinguish young febrile children with bacterial or respiratory viral infections... - Predictors of occult pneumococcal bacteremia in young febrile childrenN Kuppermann
Department of Internal Medicine, University of California, Davis School of Medicine, USA
Ann Emerg Med 31:679-87. 1998..The purpose of this study was to identify predictors of OPB among a large cohort of young, febrile children treated as outpatients using multivariable statistical methods... - Occult bacteremia in young febrile childrenN Kuppermann
Department of Internal Medicine, University of California, Davis School of Medicine, USA
Pediatr Clin North Am 46:1073-109. 1999..A highly effective S. pneumoniae bacterial conjugate vaccine will soon be available, which will benefit all children, and will alter the ways that clinicians evaluate fully immunized young, febrile children... - The fast is positive, now what? Derivation of a clinical decision rule to determine the need for therapeutic laparotomy in adults with blunt torso trauma and a positive trauma ultrasoundJohn S Rose
Department of Emergency Medicine, University of California, Davis School of Medicine, Sacramento, California 95817, USA
J Emerg Med 29:15-21. 2005..The object of this study was to derive a clinical decision rule for therapeutic laparotomy among adult blunt trauma patients with a positive abdominal ultrasound for trauma (FAST) examination... - A decision rule for identifying children at low risk for brain injuries after blunt head traumaMichael J Palchak
Division of Emergency Medicine, Department of Internal Medicine, University of California-Davis School of Medicine, 2315 Stockton Boulevard, Davis, CA 95817, USA
Ann Emerg Med 42:492-506. 2003.... - Interobserver agreement in assessment of clinical variables in children with blunt head traumaMarc H Gorelick
Department of Pediatrics, Section of Emergency Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
Acad Emerg Med 15:812-8. 2008..The objective was to determine the interobserver agreement in the assessment of historical and physical examination findings of children undergoing emergency department (ED) evaluation for blunt head trauma... - Pediatric head trauma: changes in use of computed tomography in emergency departments in the United States over timeCharles D Blackwell
Department of Emergency Medicine, Children s Hospitals and Clinics of Minnesota, Minneapolis, MN 55404, USA
Ann Emerg Med 49:320-4. 2007..We sought to describe the use of computed tomography (CT) over time in the treatment of children with acute closed head trauma in US EDs... - Clinician judgment versus a decision rule for identifying children at risk of traumatic brain injury on computed tomography after blunt head traumaMichael J Palchak
Department of Emergency Medicine, UC Davis School of Medicine, Davis, CA 95817 2282, USA
Pediatr Emerg Care 25:61-5. 2009..To compare a decision rule with clinician judgment for identifying children at risk of traumatic brain injury (TBI) after blunt head trauma... - Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosisJohn T Kanegaye
Division of Emergency Medicine, Rady Children s Hospital San Diego, 3020 Children s Way, MC 5075, San Diego, CA 92123, USA
Pediatrics 123:e967-71. 2009..We evaluated the diagnostic utility of the presence and number of cerebrospinal fluid (CSF) bands in distinguishing bacterial from aseptic meningitis among children with CSF pleocytosis... - Risk of serious bacterial infection in young febrile infants with respiratory syncytial virus infectionsDeborah A Levine
Department of Pediatrics, New York University School of Medicine Bellevue Hospital Center, New York, New York 10016, USA
Pediatrics 113:1728-34. 2004..Specifically, it remains unclear whether the risk of SBI is altered in a meaningful way in the presence of respiratory syncytial virus (RSV) infections... - Performance of the pediatric glasgow coma scale in children with blunt head traumaJames F Holmes
Department of Emergency Medicine, University of California, Davis, School of Medicine, Sacramento, CA, USA
Acad Emerg Med 12:814-9. 2005..To compare the accuracy of a pediatric Glasgow Coma Scale (GCS) score in preverbal children with blunt head trauma with the standard GCS score in older children... - Correlation of clinical and biochemical findings with diabetic ketoacidosis-related cerebral edema in children using magnetic resonance diffusion-weighted imagingNicole S Glaser
Department of Pediatrics, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
J Pediatr 153:541-6. 2008..To determine clinical and biochemical factors influencing cerebral edema formation during diabetic ketoacidosis (DKA) in children... - Frequency of sub-clinical cerebral edema in children with diabetic ketoacidosisNicole S Glaser
Department of Pediatrics, University of California Davis School of Medicine, Sacramento 95817, USA
Pediatr Diabetes 7:75-80. 2006.... - Clinical prediction rules for identifying adults at very low risk for intra-abdominal injuries after blunt traumaJames F Holmes
Department of Emergency Medicine, UC Davis School of Medicine, Sacramento, CA 95817 2282, USA
Ann Emerg Med 54:575-84. 2009..We derive and validate clinical prediction rules to identify adult patients at very low risk for intra-abdominal injuries after blunt torso trauma... - Is hospital admission and observation required after a normal abdominal computed tomography scan in children with blunt abdominal trauma?Smita Awasthi
Department of Emergency Medicine, University of California Davis, School of Medicine, Davis, CA, USA
Acad Emerg Med 15:895-9. 2008.... - Guardian availability in children evaluated in the emergency department for blunt head traumaJames F Holmes
Department of Emergency Medicine, UC Davis School of Medicine, Sacramento, CA, USA
Acad Emerg Med 16:15-20. 2009..Enrolling children in research studies in the emergency department (ED) is typically dependent on the presence of a guardian to provide written informed consent... - Validation of a prediction rule for the identification of children with intra-abdominal injuries after blunt torso traumaJames F Holmes
Department of Emergency Medicine, University of California Davis School of Medicine, Sacramento, CA 95817 2282, USA
Ann Emerg Med 54:528-33. 2009..We validate the accuracy of a previously derived clinical prediction rule for the identification of children with intra-abdominal injuries after blunt torso trauma... - Association between the "seat belt sign" and intra-abdominal injury in children with blunt torso traumaPeter E Sokolove
Department of Emergency Medicine, University of California, Davis, School of Medicine, Sacramento, USA
Acad Emerg Med 12:808-13. 2005..To determine the association between an abdominal "seat belt sign" (SBS) and intra-abdominal injury (IAI) in children presenting to the emergency department (ED) after blunt trauma... - Mechanism of cerebral edema in children with diabetic ketoacidosisNicole S Glaser
Department of Pediatrics, Division of Emergency Medicine, University of California, Davis School of Medicine, Sacramento, California 95817, USA
J Pediatr 145:164-71. 2004..Cerebral edema during diabetic ketoacidosis (DKA) has been attributed to osmotic cellular swelling during treatment. We evaluated cerebral water distribution and cerebral perfusion during DKA treatment in children... - Do children require hospitalization after immediate posttraumatic seizures?James F Holmes
Division of Emergency Medicine, Department of Internal Medicine, University of California Davis, School of Medicine, Sacramento, CA, USA
Ann Emerg Med 43:706-10. 2004..We determine whether children with immediate posttraumatic seizures require hospitalization for observation of possible neurologic complications... - Does an isolated history of loss of consciousness or amnesia predict brain injuries in children after blunt head trauma?Michael J Palchak
Division of Emergency Medicine, Department of Internal Medicine, University of California, Davis School of Medicine, Davis, California 95817 2282, USA
Pediatrics 113:e507-13. 2004..A history of loss of consciousness (LOC) is frequently used as an indication for cranial computed tomography (CT) in the emergency department (ED) evaluation of children with blunt head trauma... - Identification of children with intra-abdominal injuries after blunt traumaJames F Holmes
Division of Emergency Medicine, Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, CA 95817 2282, USA
Ann Emerg Med 39:500-9. 2002..We sought to determine the utility of laboratory testing after adjusting for physical examination findings in the identification of children with intra-abdominal injuries after blunt trauma... - The evaluation and management of children with diabetic ketoacidosis in the emergency departmentNicole Glaser
Department of Pediatrics, Emergency Medicine and Pediatrics, University of California at Davis, School of Medicine, Sacramento, CA 95817, USA
Pediatr Emerg Care 20:477-81; quiz 482-4. 2004 - Cricoid ring integrity: implications for cricothyrotomyAaron E Bair
Division of Emergency Medicine, Department of Internal Medicine, University of California Davis, 2315 Stockton Boulevard, PSSB 2100, Sacramento, CA 95817, USA
Ann Emerg Med 41:331-7. 2003..The objectives of this study were to compare the requisite forces for intubation and the structural tolerances of the cricoid ring between the single- and double-hook techniques... - A clinical decision rule for identifying children with thoracic injuries after blunt torso traumaJames F Holmes
Division of Emergency Medicine, Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, CA 95817 2282, USA
Ann Emerg Med 39:492-9. 2002..We sought to determine the prevalence of thoracic injuries in children sustaining blunt torso trauma and to develop a clinical prediction rule to identify children with these injuries... - Predictors of bacteremia in febrile children with sickle cell diseaseDaniel C West
Department of Pediatrics, Division of Emergency Medicine, School of Medicine, University of California, Davis, Sacramento, California 95817, USA
J Pediatr Hematol Oncol 24:279-83. 2002..The purpose of this study was to test whether clinical and hematologic variables commonly used to predict bacteremia in normal young children with fever could accurately predict bacteremia in febrile children with SCD... - Quality of care of children in the emergency department: association with hospital setting and physician trainingMadan Dharmar
Department of Pediatrics, University of California Davis, Sacramento, CA, USA
J Pediatr 153:783-9. 2008..To investigate differences in the quality of emergency care for children related to differences in hospital setting, physician training, and demographic factors... - Cerebrospinal latex agglutination fails to contribute to the microbiologic diagnosis of pretreated children with meningitisLise E Nigrovic
Division of Emergency Medicine, Children's Hospital, Boston, MA, USA
Pediatr Infect Dis J 23:786-8. 2004..Clinical decision-making algorithms for the management of pretreated patients at risk for bacterial meningitis should not include latex agglutination testing... - Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edemaJames P Marcin
Department of Pediatrics and the Division of Emergency Medicine, University of California, Davis, School of Medicine, Davis, USA
J Pediatr 141:793-7. 2002..Greater neurologic depression at the time of diagnosis of cerebral edema and a higher initial serum urea nitrogen concentration are also associated with poor outcome... - Epidemiology of a pediatric emergency medicine research network: the PECARN Core Data ProjectElizabeth R Alpern
Department of Pediatrics, Division of Emergency Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatr Emerg Care 22:689-99. 2006..To examine the epidemiology of pediatric patient visits to emergency departments (ED)... - Summary of NIH Medical-Surgical Emergency Research Roundtable held on April 30 to May 1, 2009Amy H Kaji
Department of Emergency Medicine, Harbor UCLA Medical Center, 1000 W Carson Street, Box 21, Torrance, CA 90509 2910, USA
Ann Emerg Med 56:522-37. 2010.... - Revisiting the emergency medicine services for children research agenda: priorities for multicenter research in pediatric emergency careSteven Zane Miller
Department of Pediatrics, Division of Pediatric Emergency Medicine, Morgan Stanley Children s Hospital of New York Presbyterian, Columbia University Medical Center, New York, NY, USA
Acad Emerg Med 15:377-83. 2008..They sought to prioritize PECARN research efforts, to guide investigators planning to conduct research in PECARN, and to describe the creation of a prioritized EMSC research agenda specific for multicenter research... - Comparison of prediction models for adverse outcome in pediatric meningococcal disease using artificial neural network and logistic regression analysesTran Nguyen
Department of Pediatrics, Kaiser Permanente, Sacramento, CA, USA
J Clin Epidemiol 55:687-95. 2002..With larger, more complete databases, and with advanced ANN algorithms, this technology may become increasingly useful for real-time prediction of patient outcome... - Risk factors for traumatic or unsuccessful lumbar punctures in childrenLise E Nigrovic
Division of Emergency Medicine, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
Ann Emerg Med 49:762-71. 2007..We sought to determine patient, physician, and procedural factors associated with traumatic and unsuccessful lumbar punctures in children... - Availability of pediatric emergency visit data from existing data sourcesMarc H Gorelick
Section of Emergency Medicine, Department of Pediatrics, Medical College of Wisconsin and Children s Research Institute MHG, Children s Hospital of Wisconsin, Milwaukee, WI 53226, USA
Acad Emerg Med 12:1195-200. 2005..To determine the availability and completeness of selected data elements from administrative and clinical sources for emergency department (ED) visits in a national pediatric research network... - Clinical and demographic factors associated with urinary tract infection in young febrile infantsJoseph J Zorc
Department of Pediatrics, University of Pennsylvania School of Medicine, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Pediatrics 116:644-8. 2005..The objective of this study was to identify clinical and demographic factors associated with UTI in febrile infants who are < or =60 days of age using a prospective multicenter cohort... - Twenty years of emergency medical services for children: a cause for celebration and a call for actionSteven Krug
Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611-3008, USA
Pediatrics 115:1089-91. 2005 - Detection of cerebral {beta}-hydroxy butyrate, acetoacetate, and lactate on proton MR spectroscopy in children with diabetic ketoacidosisSandra L Wootton-Gorges
Department Radiology, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
AJNR Am J Neuroradiol 26:1286-91. 2005..Care should be taken in interpreting MRS results in patients with DKA to avoid erroneously attributing betaOHB peaks to lactate... - Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine eraLise E Nigrovic
Division of Emergency Medicine, Children s Hospital, Boston, MA, USA
Acad Emerg Med 15:522-8. 2008..The epidemiology of bacterial meningitis in children in the era of widespread heptavalent conjugate pneumococcal vaccination (PCV7) is unknown... - Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitisLise E Nigrovic
Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Pediatr Emerg Care 25:112-7; quiz 118-20. 2009.... - Structure and function of emergency care research networks: strengths, weaknesses, and challengesLinda Papa
Department of Emergency Medicine, Orlando Regional Medical Center, Orlando, FL, USA
Acad Emerg Med 16:995-1004. 2009..By leveraging the strengths and addressing the weaknesses, strategies can be adopted to enhance the scientific value and productivity of these networks and give direction to future ECRNs... - Development of the capacity necessary to perform and promote knowledge translation research in emergency medicinePeter S Dayan
Department of Pediatrics, The Morgan Stanley Children s Hospital of New York Presbyterian, Columbia University College of Physicians and Surgeons, New York, NY, USA
Acad Emerg Med 14:978-83. 2007..Finally, we see the need to further develop and support EM research networks, as these networks will be both the clinical laboratories in which to perform the KT research and the incubators for the development of EM KT research experts... - Lack of agreement in pediatric emergency department discharge diagnoses from clinical and administrative data sourcesMarc H Gorelick
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
Acad Emerg Med 14:646-52. 2007..Diagnosis information from existing data sources is used commonly for epidemiologic, administrative, and research purposes. The quality of such data for emergency department (ED) visits is unknown... - Child abuse presenting as pseudorenal failure with a history of a bicycle fallJennifer W Yang
Department of Pediatrics, University of California Davis Medical Center, Sacramento, California 95817, USA
Pediatr Emerg Care 18:91-2. 2002 - Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae eraLise E Nigrovic
Department of Medicine, Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Pediatrics 110:712-9. 2002..CONCLUSIONS: The BMS accurately identifies children at low (BMS = 0) or high (BMS > or =2) risk of bacterial meningitis. Outpatient management may be considered for children in the low-risk group... - Loss of consciousness and/or amnesia after blunt head trauma in childrenNathan Kuppermann
Pediatr Crit Care Med 6:93-4. 2005 - Ventilation in pediatric diabetic ketoacidosis--not too much, but not too littleJames P Marcin
Pediatr Crit Care Med 6:489-90. 2005 - A comment on "The risky business of assessing research risk"Nicole Glaser
Am J Bioeth 7:W5-6. 2007 - DKA-related cerebral edema and intravenous fluid therapy: potential pitfalls of uncontrolled retrospective studiesNicole Glaser
J Pediatr 152:145; author reply 147-9. 2008 - A multicenter, randomized, controlled trial of dexamethasone for bronchiolitisHoward M Corneli
University of Utah, Salt Lake City, USA
N Engl J Med 357:331-9. 2007..Corticosteroids are commonly used to treat bronchiolitis, but evidence of their effectiveness is limited... - Twenty years of emergency medical services for children--a cause for celebration and a call for actionSteven Krug
Acad Emerg Med 12:345-7. 2005 - Young men were at risk of becoming lost to follow-up in a cohort of head-injured adultsPhil Edwards
CRASH trials Co ordinating Centre, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
J Clin Epidemiol 60:417-24. 2007..This study is to identify predictors of loss to follow-up among adults with head injury... - The evaluation of young febrile children for occult bacteremia: time to reevaluate our approach?Nathan Kuppermann
Arch Pediatr Adolesc Med 156:855-7. 2002 - Twenty years of emergency medical services for children: a cause for celebration and a call for actionSteven Krug
Pediatr Emerg Care 21:223-6. 2005 - A new prognostic scoring system for meningococcal septic shock in children: comparison with three other scoring systemsNathan Kuppermann
Intensive Care Med 29:333; author reply 334. 2003 - Sterile cerebrospinal fluid pleocytosis in young infants with urinary tract infectionsSamir S Shah
Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Pediatr 153:290-2. 2008..Among patients with urinary tract infections and without traumatic lumbar punctures, sterile cerebrospinal fluid pleocytosis was uncommon (0%-8%, depending on the definition) in contrast to earlier studies reporting this association... - Derivation of clinical prediction rules to identify children with fractures after twisting injuries of the anklePeter S Dayan
Children s Hospital of New York Presbyterian, Columbia University College of Physicians and Surgeons, New York, NY, USA
Acad Emerg Med 11:736-43. 2004..The authors sought to derive maximally sensitive prediction rules for identifying children with significant fractures after acute twisting injuries to the ankle... - Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitisLise E Nigrovic
Department of Medicine, Children s Hospital Boston and Harvard Medical School, Boston, Mass 02115, USA
JAMA 297:52-60. 2007.... - Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitisLise E Nigrovic
Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Pediatrics 122:726-30. 2008..The goal of this study was to evaluate the effect of antibiotic administration before lumbar puncture on cerebrospinal fluid profiles in children with bacterial meningitis...
Research Grants
- Fluid Therapy and Cerebral Injury in Pediatric Diabetic KetoacidosisNATHAN contact KUPPERMANN; Fiscal Year: 2010..In the proposed study, we plan to compare four different DKA treatment regimens to determine which regimen results in the least risk of brain injury. ..