Research Topics
| M KuppermannSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Preferences for outcomes associated with decisions to undergo or forgo genetic testing for Lynch syndromeMiriam Kuppermann
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, USA
Cancer 119:215-25. 2013..Little is known, however, regarding how patients view the prospect of such testing. In addition, data on preferences (utilities) for the potential outcomes of testing decisions for use in cost-effectiveness analyses are lacking...
Preferences for surveillance strategies for women treated for high-grade precancerous cervical lesionsM Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, Medical Effectiveness Research Center for Diverse Populations, University of California San Francisco, 3333 California Street, San Francisco, CA 94143, USA
Gynecol Oncol 118:108-15. 2010..We measured and compared patient preferences (utilities) for scenarios with varying surveillance strategies and outcomes to inform guidelines and cost-effectiveness analyses of post-treatment surveillance options...- Attitudes toward prenatal testing and pregnancy termination among a diverse population of parents of children with intellectual disabilitiesMiriam Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of California, San Francisco, CA 94143 0856, USA
Prenat Diagn 31:1251-8. 2011..To determine how parents of children with intellectual disabilities view prenatal testing and pregnancy termination for their child's condition... 
Effect of hysterectomy vs medical treatment on health-related quality of life and sexual functioning: the medicine or surgery (Ms) randomized trialMiriam Kuppermann
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA 94143 0856, USA
JAMA 291:1447-55. 2004..Although a quarter of US women undergo elective hysterectomy before menopause, controlled trials that evaluate the benefits and harms are lacking...- Predictors of hysterectomy use and satisfactionMiriam Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94143 0856, USA
Obstet Gynecol 115:543-51. 2010..To identify static and time-varying sociodemographic, clinical, health-related quality-of-life and attitudinal predictors of use and satisfaction with hysterectomy for noncancerous conditions... - Effect of noncancerous pelvic problems on health-related quality of life and sexual functioningMiriam Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94143 0856, USA
Obstet Gynecol 110:633-42. 2007..To assess the effect of abnormal uterine bleeding and pelvic pain and pressure on health-related quality of life and sexual functioning and assess treatment satisfaction... - Computerized prenatal genetic testing decision-assisting tool: a randomized controlled trialMiriam Kuppermann
Departments of Obstetrics, University of California, San Francisco, California, USA
Obstet Gynecol 113:53-63. 2009..We sought to estimate the effect of a computerized, interactive prenatal testing decision tool on prenatal testing decision making... - Procedure-related miscarriages and Down syndrome-affected births: implications for prenatal testing based on women's preferencesM Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of California, San Francisco, California 94143 0856, USA
Obstet Gynecol 96:511-6. 2000..To determine how pregnant women of varying ages, races, ethnicities, and socioeconomic backgrounds value procedure-related miscarriage and Down-syndrome-affected birth... - Preferences of women facing a prenatal diagnostic choice: long-term outcomes matter mostM Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of California, San Francisco, 94143 0856, USA
Prenat Diagn 19:711-6. 1999..Furthermore, the substantial variation in utilities we observed suggests that future prenatal testing policies should account for the preferences of the individual woman... - Sexual functioning after total compared with supracervical hysterectomy: a randomized trialMiriam Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, California 94143, USA
Obstet Gynecol 105:1309-18. 2005.... - How do women of diverse backgrounds value prenatal testing outcomes?Miriam Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of California, San Francisco, California 94143, USA
Prenat Diagn 24:424-9. 2004..To describe women's preferences for prenatal testing outcomes and to explore their association with sociodemographic characteristics and attitudes... - Beyond race or ethnicity and socioeconomic status: predictors of prenatal testing for Down syndromeMiriam Kuppermann
Department of Obstetrics, University of California, San Francisco, California 94143 0856, USA
Obstet Gynecol 107:1087-97. 2006..To identify predictors of prenatal genetic testing decisions and explore whether racial or ethnic and socioeconomic differences are explained by knowledge, attitudes, and preferences... - Decision analysis of prenatal testing for chromosomal disorders: what do the preferences of pregnant women tell us?R A Harris
Department of Obstetrics, School of Medicine, University of California, San Francisco 94143 0856, USA
Genet Test 5:23-32. 2001..For counseling purposes, how an individual values the presence and timing of fetal chromosomal information should be carefully understood... - Can preference scores for discrete states be used to derive preference scores for an entire path of events? An application to prenatal diagnosisM Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, USA
Med Decis Making 17:42-55. 1997.... - Who should be offered prenatal diagnosis? The 35-year-old questionM Kuppermann
Department of Obstetrics, Gynecology, and Reproductive Sciences, San Francisco, CA 94143 0856, USA
Am J Public Health 89:160-3. 1999..We conclude that guidelines regarding use of prenatal diagnosis account for the preferences of the individual patient as well as for individual risk... - Cost utility of prenatal diagnosis and the risk-based thresholdRyan A Harris
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA
Lancet 363:276-82. 2004..Current guidelines should be changed to offer testing to all pregnant women, not just those whose risk of carrying an affected fetus exceeds a specified threshold... - Sexual function and aging in racially and ethnically diverse womenAlison J Huang
Department of Medicine, University of California at San Francisco, San Francisco, California, USA
J Am Geriatr Soc 57:1362-8. 2009..To examine factors influencing sexual activity and functioning in racially and ethnically diverse middle-aged and older women... - The day-to-day impact of urogenital aging: perspectives from racially/ethnically diverse womenAlison J Huang
Department of Medicine, University of California, San Francisco, CA, USA
J Gen Intern Med 25:45-51. 2010..Urogenital symptoms affect up to half of women after menopause, but their impact on women's day-to-day functioning and wellbeing is poorly understood... - Predictors of hysterectomy in women with common pelvic problems: a uterine survival analysisLee A Learman
Department of Obstetrics, Gynecology and Reproductive Sciences and Medical Effectiveness Research Center for Diverse Populations, University of California San Francisco School of Medicine, San Francisco, CA 94110, USA
J Am Coll Surg 204:633-41. 2007..We followed a prospective cohort of women with common pelvic problems to determine whether simple clinical characteristics could predict a subsequent hysterectomy... - A community-based study of acne-related health preferences in adolescentsCynthia L Chen
School of Medicine, University of California, San Francisco, CA, USA
Arch Dermatol 144:988-94. 2008..To examine preferences for acne-related outcomes in adolescents... - Assessment of demand for prenatal diagnostic testing using willingness to payAaron B Caughey
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, 505 Parnassus Avenue, Box 0132, San Francisco, CA 94143, USA
Obstet Gynecol 103:539-45. 2004.... - Objective and subjective assessments of socioeconomic status and their relationship to self-rated health in an ethnically diverse sample of pregnant womenJ M Ostrove
Program in Health Psychology, University of California, San Francisco, USA
Health Psychol 19:613-8. 2000.... - Tamoxifen for breast cancer risk reduction: impact of alternative approaches to quality-of-life adjustment on cost-effectiveness analysisJoy Melnikow
Department of Family and Community Medicine, University of California, Davis, Sacramento, California 95817, USA
Med Care 46:946-53. 2008..In cost-effectiveness analysis (CEA), the effects of health-care interventions on multiple health dimensions typically require consideration of both quantity and quality of life... - Factors associated with undergoing bilateral salpingo-oophorectomy at the time of hysterectomy for benign conditionsVanessa L Jacoby
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California 94115, USA
Obstet Gynecol 113:1259-67. 2009..To identify possible factors associated with undergoing bilateral salpingo-oophorectomy (BSO) at the time of hysterectomy among women with benign conditions... - Racial and ethnic disparities in benign gynecologic conditions and associated surgeriesVanessa L Jacoby
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA, USA
Am J Obstet Gynecol 202:514-21. 2010..Further research is needed to better define racial and ethnic differences in these conditions and to examine the complex mechanisms that may result in associated health disparities... - Social and familial context of prenatal genetic testing decisions: are there racial/ethnic differences?Lee A Learman
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, USA
Am J Med Genet C Semin Med Genet 119:19-26. 2003..However, substantial variation within groups and overlap between groups suggest that racial/ethnic differences play a small role in the social and familial context of prenatal genetic testing decisions... - Oophorectomy in premenopausal women: health-related quality of life and sexual functioningVanessa Teplin
Veterans Administration Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
Obstet Gynecol 109:347-54. 2007..To compare health-related quality-of-life outcomes and sexual functioning among premenopausal women who underwent bilateral salpingo-oophorectomy (BSO) versus ovarian conservation at the time of hysterectomy... - Quality and equality in obstetric care: racial and ethnic differences in caesarean section delivery ratesAllison S Bryant
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA 94143 0132, USA
Paediatr Perinat Epidemiol 23:454-62. 2009..Disparities in risk-adjusted CS should be considered as a quality metric for obstetric care, whether at the national, state, hospital or provider level... - Oophorectomy vs ovarian conservation with hysterectomy: cardiovascular disease, hip fracture, and cancer in the Women's Health Initiative Observational StudyVanessa L Jacoby
Departments of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA 94115, USA
Arch Intern Med 171:760-8. 2011..Elective bilateral salpingo-oophorectomy (BSO) is routinely performed with hysterectomy for benign conditions despite conflicting data on long-term outcomes... - Hysterectomy versus expanded medical treatment for abnormal uterine bleeding: clinical outcomes in the medicine or surgery trialLee A Learman
Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of California, San Francisco, California, USA
Obstet Gynecol 103:824-33. 2004..To compare clinical outcomes after randomization to hysterectomy versus medical treatment in patients with chronic abnormal uterine bleeding refractory to medroxyprogesterone acetate... - Race/Ethnicity and pregnancy decision making: the role of fatalism and subjective social standingAllison S Bryant
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94143 0132, USA
J Womens Health (Larchmt) 19:1195-200. 2010..Rates of unintended pregnancy in the United States differ by race and ethnicity. We examined whether these differences might be explained by maternal fatalism and subjective social standing... - Abortion attitudes of pregnant women in prenatal careLee A Learman
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, USA
Am J Obstet Gynecol 192:1939-45; discussion 1945-7. 2005..These findings underscore the need for early prenatal genetic counseling, screening, and testing... - Resource use for total and supracervical hysterectomies: results of a randomized trialJonathan Showstack
Department of Medicine, School of Medicine, University of California, San Francisco, California 94118 1944, USA
Obstet Gynecol 103:834-41. 2004..We report here an analysis of 24-month resource use by patients in this trial... - Prenatal testing guidelines: time for a new approachMiriam Kuppermann
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA 94143 0856, USA
Gynecol Obstet Invest 60:6-10. 2005.... - Management of the low-grade abnormal Pap smear: What are women's preferences?Joy Melnikow
Department of Family and Community Medicine, University of California, Davis, Sacramento 95817, USA
J Fam Pract 51:849-55. 2002..To evaluate preferences among ethnically diverse women for the management of a low-grade abnormal Pap smear result: early colposcopy or observation with repeat Pap smears... - Perceived risk of prenatal diagnostic procedure-related miscarriage and Down syndrome among pregnant womenAaron B Caughey
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA
Am J Obstet Gynecol 198:333.e1-8. 2008..The objective of the study was to identify correlates of perceived risk of carrying a Down syndrome-affected fetus or experiencing a procedure-related miscarriage among a diverse group of pregnant women... - Sleep problems and their correlates in a working populationM Kuppermann
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco 94120, USA
J Gen Intern Med 10:25-32. 1995..A single question about sleep problems may serve as an effective screen for identifying primary care patients with mental health problems, as well as underlying sleep disorders... - Nuchal translucency and first trimester biochemical markers for down syndrome screening: a cost-effectiveness analysisAaron B Caughey
Department of Obstetrics and Gynecology, University of California, San Francisco, USA
Am J Obstet Gynecol 187:1239-45. 2002..The purpose of this study was to perform a cost-effectiveness analysis that compared the first- and second- trimester screening tools for Down syndrome... - Patient willingness to participate in a clinical trial with preimplantation genetic diagnosisLora K Shahine
University of California at San Francisco, Department of Reproductive Endocrinology and Infertility, San Francisco, California, USA
Fertil Steril 89:879-84. 2008..To investigate patients' interest in preimplantation genetic diagnosis (PGD) as a method for aneuploidy screening and their willingness to participate in a clinical trial using PGD... - Recruitment strategies for minority participation: challenges and cost lessons from the POWER interviewJanet Fulton Keyzer
Center for Health Services Research in Primary Care, University of California, Davis, Sacramento, CA 95817, USA
Ethn Dis 15:395-406. 2005..The importance of recruiting and retaining women from diverse populations is well recognized; however, the recruitment process often presents greater challenges at higher costs than initially anticipated... - Randomized trial of medical treatment versus hysterectomy for abnormal uterine bleeding: resource use in the Medicine or Surgery (Ms) trialJonathan Showstack
Department of Medicine, University of California, San Francisco, CA, USA
Am J Obstet Gynecol 194:332-8. 2006.... - Development and validation of a sexual functioning measure for use in diverse women's health outcome studiesLee A Learman
Department of Obstetrics, University of California, San Francisco, School of Medicine, San Francisco, CA, USA
Am J Obstet Gynecol 198:710.e1-8; discussion 710.e8-9. 2008..The objective of the study was to evaluate the psychometric properties of the Sexual Health Outcomes in Women Questionnaire (SHOW-Q)... - Surveillance after treatment for cervical intraepithelial neoplasia: outcomes, costs, and cost-effectivenessJoy Melnikow
Department of Economics, Center for Healthcare Policy and Research, University of California, Davis, California 95817, USA
Obstet Gynecol 116:1158-70. 2010..To estimate outcomes and costs of surveillance strategies after treatment for high-grade cervical intraepithelial neoplasia (CIN)... - "I'm going to die of something anyway": women's perceptions of tamoxifen for breast cancer risk reductionDebora A Paterniti
Center for Health Services Research in Primary Care, University of California, Davis, Sacramento, CA 95817, USA
Ethn Dis 15:365-72. 2005..To investigate how ethnically diverse women who are eligible for tamoxifen prophylaxis because of their breast cancer risk decide about tamoxifen use for risk reduction... - The effect of ultralow-dose transdermal estradiol on sexual function in postmenopausal womenAlison Huang
Department of Medicine, University of California San Francisco School of Medicine, San Francisco, CA, USA
Am J Obstet Gynecol 198:265.e1-7. 2008..This study was undertaken to examine the effect of ultralow-dose transdermal estradiol on sexual function in postmenopausal women... - Preferences of Women Evaluating Risks of Tamoxifen (POWER) study of preferences for tamoxifen for breast cancer risk reductionJoy Melnikow
Department of Family and Community Medicine, University of California Davis, Sacramento, California 95817, USA
Cancer 103:1996-2005. 2005..The objective of this study was to understand the attitudes and preferences of risk-eligible women regarding use of tamoxifen for breast cancer risk reduction... - Perceptions of prenatal testing for birth defects among rural LatinasCourtney Griffiths
Lucile Packard Children s Hospital, Stanford University Hospital and Clinics, Stanford, CA, USA
Matern Child Health J 12:34-42. 2008..Educational efforts and counseling should include clear communication regarding the goals of prenatal screening programs to help these women make informed testing decisions that are reflective of their values and preferences... - Medicine or Surgery (Ms): a randomized clinical trial comparing hysterectomy and medical treatment in premenopausal women with abnormal uterine bleedingR Edward Varner
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 619 South 19th Street, NHB 219, Birmingham, AL 35249 7333, USA
Control Clin Trials 25:104-18. 2004..02) and a greater prevalence of incontinence (44% vs. 16%; p=0.046). Although recruitment was difficult, we have completed enrollment in a randomized clinical trial comparing surgical and medical treatments for abnormal uterine bleeding... - Risks, values, and decision making surrounding pregnancyAnne Drapkin Lyerly
Department of Obstetrics and Gynecology and Trent Center for Bioethics, Humanities, and History of Medicine, Duke University Medical Center, Durham, North Carolina, USA
Obstet Gynecol 109:979-84. 2007..These tendencies in the perception, communication, and management of risk can lead to care that is neither evidence-based nor patient-centered, often to the detriment of both women and infants... - Mode of delivery: toward responsible inclusion of patient preferencesMargaret Olivia Little
Georgetown University, Washington DC 20057, USA
Obstet Gynecol 112:913-8. 2008.... - Chemoprevention: drug pricing and mortality: the case of tamoxifenJoy Melnikow
Department of Family and Community Medicine, University of California Davis, Sacramento, California 95817, USA
Cancer 107:950-8. 2006..Tamoxifen is a prototypic cancer chemopreventive agent, yet clinical trials have not evaluated its effect on mortality or the impact of drug pricing on its cost-effectiveness... - Conservative versus aggressive follow up of mildly abnormal Pap smears: testing for process utilityStephen Birch
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
Health Econ 12:879-84. 2003..We also found that relative preferences among different processes may depend on the particular circumstances or pathologies being considered...
Research Grants
- Expanded Prenatal Testing Options and Informed ChoiceMiriam Kuppermann; Fiscal Year: 2010..In short, this study will generate a useful decision-assisting tool and provide information for use in designing cost-effective testing programs that allow for variation in preferences. ..
- Expanded Prenatal Testing Options and Informed ChoiceMiriam Kuppermann; Fiscal Year: 2007..In short, this study will generate a useful decision-assisting tool and provide information for use in designing cost-effective testing programs that allow for variation in preferences. ..
- Intermediate Outcomes of Hysterectomy and AlternativesMiriam Kuppermann; Fiscal Year: 2006..abstract_text> ..
- Expanded Prenatal Testing Options and Informed ChoiceMiriam Kuppermann; Fiscal Year: 2009..In short, this study will generate a useful decision-assisting tool and provide information for use in designing cost-effective testing programs that allow for variation in preferences. ..