Sanjiv Kumra

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. doi request reprint From bench to bedside: translating new research from genetics and neuroimaging into treatment development for early-onset schizophrenia
    Sanjiv Kumra
    Division of Child and Adolescent Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55454, USA
    Early Interv Psychiatry 3:243-58. 2009
  2. doi request reprint Parietal lobe volume deficits in adolescents with schizophrenia and adolescents with cannabis use disorders
    Sanjiv Kumra
    University of Minnesota, USA
    J Am Acad Child Adolesc Psychiatry 51:171-80. 2012
  3. pmc Efficacy and tolerability of second-generation antipsychotics in children and adolescents with schizophrenia
    Sanjiv Kumra
    Division of Child and Adolescent Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Schizophr Bull 34:60-71. 2008
  4. pmc Clozapine versus "high-dose" olanzapine in refractory early-onset schizophrenia: an open-label extension study
    Sanjiv Kumra
    Department of Child and Adolescent Psychiatry, University of Minnesota, Minneapolis, Minnesota 55454 1495, USA
    J Child Adolesc Psychopharmacol 18:307-16. 2008
  5. ncbi request reprint Clozapine and "high-dose" olanzapine in refractory early-onset schizophrenia: a 12-week randomized and double-blind comparison
    Sanjiv Kumra
    Department of Child and Adolescent Psychiatry, University of Minnesota, Minneapolis, Minnesota 55454 1495, USA
    Biol Psychiatry 63:524-9. 2008
  6. pmc Gray matter volume deficits are associated with motor and attentional impairments in adolescents with schizophrenia
    Sanjiv Kumra
    University of Minnesota, Department of Psychiatry, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 35:939-43. 2011
  7. ncbi request reprint Is there a role for clozapine in the treatment of children and adolescents?
    Robert L Findling
    Department of Psychiatry, University Hospitals of Cleveland Case Western Reserve University, USA
    J Am Acad Child Adolesc Psychiatry 46:423-8. 2007
  8. ncbi request reprint Hematological adverse events in clozapine-treated children and adolescents
    Ginny Gerbino-Rosen
    Bronx Children s Psychiatric Center, Division of Child and Adolescent Psychiatry, Department of Psychiatry, Albert Einstein College of Medicine, Bronx, NY, USA
    J Am Acad Child Adolesc Psychiatry 44:1024-31. 2005
  9. doi request reprint Selective neurocognitive impairments in adolescents with major depressive disorder
    Georges Han
    Department of Psychiatry, University of Minnesota Medical School, USA
    J Adolesc 35:11-20. 2012
  10. ncbi request reprint Clozapine: its impact on aggressive behavior among children and adolescents with schizophrenia
    Harvey Kranzler
    Bronx Children s Psychiatric Center, Department of Psychiatry, Albert Einstein College of Medicine, Bronx, USA
    J Am Acad Child Adolesc Psychiatry 44:55-63. 2005

Research Grants

  1. Treating Refractory Childhood Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2004
  2. Cannabis and Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2006
  3. Cannabis and Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2007
  4. Cannabis and Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2009
  5. Cannabis and Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2010

Collaborators

Detail Information

Publications33

  1. doi request reprint From bench to bedside: translating new research from genetics and neuroimaging into treatment development for early-onset schizophrenia
    Sanjiv Kumra
    Division of Child and Adolescent Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55454, USA
    Early Interv Psychiatry 3:243-58. 2009
    ..This overview examines recent research on the neurobiological alterations, possible causes, developmental trajectory and treatment of EOS and attempts to identify gaps in the field...
  2. doi request reprint Parietal lobe volume deficits in adolescents with schizophrenia and adolescents with cannabis use disorders
    Sanjiv Kumra
    University of Minnesota, USA
    J Am Acad Child Adolesc Psychiatry 51:171-80. 2012
    ..This study characterized cerebral cortical gray matter structure in adolescents in regions of interest (ROIs) that have been implicated in EOS and cannabis use disorders (CUD)...
  3. pmc Efficacy and tolerability of second-generation antipsychotics in children and adolescents with schizophrenia
    Sanjiv Kumra
    Division of Child and Adolescent Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Schizophr Bull 34:60-71. 2008
    ..Such a substantial risk points to the urgent need to develop therapeutic strategies to prevent and/or mitigate weight gain and diabetes early in the course of treatment in this population...
  4. pmc Clozapine versus "high-dose" olanzapine in refractory early-onset schizophrenia: an open-label extension study
    Sanjiv Kumra
    Department of Child and Adolescent Psychiatry, University of Minnesota, Minneapolis, Minnesota 55454 1495, USA
    J Child Adolesc Psychopharmacol 18:307-16. 2008
    ....
  5. ncbi request reprint Clozapine and "high-dose" olanzapine in refractory early-onset schizophrenia: a 12-week randomized and double-blind comparison
    Sanjiv Kumra
    Department of Child and Adolescent Psychiatry, University of Minnesota, Minneapolis, Minnesota 55454 1495, USA
    Biol Psychiatry 63:524-9. 2008
    ..The present study evaluated the effectiveness and safety of clozapine versus "high-dose" olanzapine in treatment-refractory adolescents with schizophrenia...
  6. pmc Gray matter volume deficits are associated with motor and attentional impairments in adolescents with schizophrenia
    Sanjiv Kumra
    University of Minnesota, Department of Psychiatry, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 35:939-43. 2011
    ..Our findings point to widespread, perhaps multifocal, pathology as contributing to cognitive dysfunction in adolescents with schizophrenia...
  7. ncbi request reprint Is there a role for clozapine in the treatment of children and adolescents?
    Robert L Findling
    Department of Psychiatry, University Hospitals of Cleveland Case Western Reserve University, USA
    J Am Acad Child Adolesc Psychiatry 46:423-8. 2007
  8. ncbi request reprint Hematological adverse events in clozapine-treated children and adolescents
    Ginny Gerbino-Rosen
    Bronx Children s Psychiatric Center, Division of Child and Adolescent Psychiatry, Department of Psychiatry, Albert Einstein College of Medicine, Bronx, NY, USA
    J Am Acad Child Adolesc Psychiatry 44:1024-31. 2005
    ..To retrospectively examine rates of hematological adverse events (HAEs) in psychiatrically ill, hospitalized children treated with clozapine...
  9. doi request reprint Selective neurocognitive impairments in adolescents with major depressive disorder
    Georges Han
    Department of Psychiatry, University of Minnesota Medical School, USA
    J Adolesc 35:11-20. 2012
    ..Findings demonstrate that adolescents with MDD display selective neurocognitive impairments on tasks capturing 'cool' and 'hot' executive functioning...
  10. ncbi request reprint Clozapine: its impact on aggressive behavior among children and adolescents with schizophrenia
    Harvey Kranzler
    Bronx Children s Psychiatric Center, Department of Psychiatry, Albert Einstein College of Medicine, Bronx, USA
    J Am Acad Child Adolesc Psychiatry 44:55-63. 2005
    ..To evaluate the effectiveness of clozapine on aggressive behavior for treatment-refractory adolescents (age range 8.5-18) with schizophrenia (295.x) at Bronx Children's Psychiatric Center...
  11. doi request reprint A comparative pilot study of second-generation antipsychotics in children and adolescents with schizophrenia-spectrum disorders
    Jonathan B Jensen
    University of Minnesota, Department of Psychiatry, Minneapolis, Minnesota 55454, USA
    J Child Adolesc Psychopharmacol 18:317-26. 2008
    ..To plan the design of a subsequent randomized controlled trial (RCT), the authors conducted this pilot study to demonstrate the feasibility of the treatment and measurement protocols...
  12. ncbi request reprint Treatment-refractory schizophrenia in children and adolescents: an update on clozapine and other pharmacologic interventions
    Harvey N Kranzler
    Department of Psychiatry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Child Adolesc Psychiatr Clin N Am 15:135-59. 2006
    ....
  13. ncbi request reprint Schizophrenia and cannabis use
    Sanjiv Kumra
    Division of Child Psychiatry, University of Minnesota, USA
    Minn Med 90:36-8. 2007
    ..This putative mechanism may explain the deficits in working memory and worsening in the severity of clinical symptoms in adolescents with schizophrenia who use cannabis...
  14. doi request reprint Paediatric major depressive disorder: neurobiology and implications for early intervention
    Kathryn Cullen
    Psychiatry Department, Medical School, University of Minnesota, Minneapolis, Minnesota, USA
    Early Interv Psychiatry 3:178-88. 2009
    ..The goals of this review are (i) to integrate how developing biological systems contribute to the pathophysiology of paediatric MDD, and (ii) to consider the role of early intervention for depressed youth...
  15. pmc Limbic structures and networks in children and adolescents with schizophrenia
    Tonya White
    Department of Psychiatry, Fairview University Medical Center, University of Minnesota, Minneapolis, MN 55454, USA
    Schizophr Bull 34:18-29. 2008
    ..Additional research within a developmental framework is necessary to determine the putative etiologic roles for limbic and other brain abnormalities in early-onset schizophrenia...
  16. pmc A preliminary study of functional connectivity in comorbid adolescent depression
    Kathryn R Cullen
    University of Minnesota Medical School, Department of Psychiatry, Minneapolis, MN, United States
    Neurosci Lett 460:227-31. 2009
    ..We conclude that hypothesis-driven, seed-based analyses of resting state fMRI data hold promise for advancing our current understanding of abnormal development of neural circuitry in adolescents with MDD...
  17. ncbi request reprint Pediatric depression: issues and treatment recommendations
    Kathryn Cullen
    Division of Child and Adolescent Psychiatry, University of Minnesota, USA
    Minn Med 92:45-8. 2009
    ....
  18. doi request reprint Substance abuse and psychosis
    Danielle Goerke
    Division of Child and Adolescent Psychiatry, University of Minnesota Medical School, F256 2B West, 2450 Riverside Avenue, Minneapolis, MN 55454, USA Electronic address
    Child Adolesc Psychiatr Clin N Am 22:643-54. 2013
    ..Treatment strategies are discussed that are effective in adult patients and that may be efficacious for youth to abstain from substances after the resolution of psychotic symptoms. ..
  19. ncbi request reprint Ethical and practical considerations in the management of incidental findings in pediatric MRI studies
    Sanjiv Kumra
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    J Am Acad Child Adolesc Psychiatry 45:1000-6. 2006
    ..The authors examined the ethical and practical management issues resulting from the detection of incidental abnormal findings on magnetic resonance imaging (MRI) research studies in healthy pediatric volunteers...
  20. ncbi request reprint Reduced frontal white matter integrity in early-onset schizophrenia: a preliminary study
    Sanjiv Kumra
    Department of Research, Zucker Hillside Hospital, Glen Oaks, New York 11004, USA
    Biol Psychiatry 55:1138-45. 2004
    ..Diffusion tensor imaging provides a relatively new approach for quantifying possible connectivity of WM in vivo...
  21. ncbi request reprint Neurocognitive profile in adolescents with early-onset schizophrenia: clinical correlates
    Joseph P Rhinewine
    Department of Psychiatry Research Zucker Hillside Hospital, Glen Oaks, New York 11004, USA
    Biol Psychiatry 58:705-12. 2005
    ..Information concerning the severity, pattern, and clinical correlates of these deficits in EOS remains limited...
  22. ncbi request reprint Correlates of substance abuse in adolescents with treatment-refractory schizophrenia and schizoaffective disorder
    Sanjiv Kumra
    Schizophr Res 73:369-71. 2005
  23. ncbi request reprint White matter abnormalities in first-episode schizophrenia or schizoaffective disorder: a diffusion tensor imaging study
    Philip R Szeszko
    The Zucker Hillside Hospital, Department of Psychiatry Research, 75 59 263rd St, Glen Oaks, NY 11004, USA
    Am J Psychiatry 162:602-5. 2005
    ..The goal of this study was to investigate brain white matter abnormalities by using diffusion tensor imaging in patients with schizophrenia or schizoaffective disorder close to illness onset...
  24. ncbi request reprint White matter abnormalities in early-onset schizophrenia: a voxel-based diffusion tensor imaging study
    Sanjiv Kumra
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    J Am Acad Child Adolesc Psychiatry 44:934-41. 2005
    ..To investigate abnormalities in the structural integrity of brain white matter as suggested by diffusion tensor imaging in adolescents with early-onset schizophrenia (onset of psychosis by age 18)...
  25. ncbi request reprint Early-onset schizophrenia is associated with impaired adolescent development of attentional capacity using the identical pairs continuous performance test
    Emily Thaden
    The Zucker Hillside Hospital, Department of Psychiatry Research 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Schizophr Res 81:157-66. 2006
    ....
  26. ncbi request reprint Deficits in memory strategy use are related to verbal memory impairments in adolescents with schizophrenia-spectrum disorders
    David Roofeh
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Schizophr Res 85:201-12. 2006
    ..To assess the nature of learning and verbal memory deficits in adolescents with schizophrenia-spectrum disorders (SzS) (i.e., schizophrenia, schizoaffective disorder, and schizophreniform disorder)...
  27. ncbi request reprint Decision-making impairments in adolescents with early-onset schizophrenia
    Hana M Kester
    Department of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Schizophr Res 85:113-23. 2006
    ..These findings have potential implications for understanding the increased vulnerability for the development of substance abuse in adolescents with schizophrenia...
  28. ncbi request reprint Anterior cingulate grey-matter deficits and cannabis use in first-episode schizophrenia
    Philip R Szeszko
    Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Br J Psychiatry 190:230-6. 2007
    ..Despite the high prevalence of cannabis use in schizophrenia, few studies have examined the potential relationship between cannabis exposure and brain structural abnormalities in schizophrenia...
  29. ncbi request reprint Neuroimaging studies of children with serious emotional disturbances: a selective review
    Jane Avery Serene
    Harvard Medical School, Boston, Massachusetts, USA
    Can J Psychiatry 52:135-45. 2007
    ....
  30. doi request reprint Cerebral glucose metabolism and D2/D3 receptor availability in young adults with cannabis dependence measured with positron emission tomography
    Serge Sevy
    The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, NY 11004, USA
    Psychopharmacology (Berl) 197:549-56. 2008
    ....
  31. pmc Editorial: research progress in early-onset schizophrenia
    Sanjiv Kumra
    Schizophr Bull 34:15-7. 2008
    ..The articles on this theme provide updated findings from brain magnetic resonance imaging, neurocognition, and clinical trials in this unique cohort...
  32. ncbi request reprint Disruption of white matter integrity in the inferior longitudinal fasciculus in adolescents with schizophrenia as revealed by fiber tractography
    Manzar Ashtari
    Department of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York, USA
    Arch Gen Psychiatry 64:1270-80. 2007
    ..There is increasing evidence that schizophrenia is characterized by abnormalities in white matter...
  33. ncbi request reprint Neurocognitive deficits in adolescents with schizophrenia: longitudinal stability and predictive utility for short-term functional outcome
    Kelly L Cervellione
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    J Am Acad Child Adolesc Psychiatry 46:867-78. 2007
    ..Here, the authors examined the longitudinal stability of neuropsychological deficits in adolescents with EOS relative to HCS and the associations of these deficits with short-term functional outcome in patients...

Research Grants6

  1. Treating Refractory Childhood Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2004
    ....
  2. Cannabis and Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2006
    ..A positive finding would help inform current neurodevelopmental models of schizophrenia and point to an intervention that might prevent worsening of the illness. ..
  3. Cannabis and Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2007
    ..A positive finding would help inform current neurodevelopmental models of schizophrenia and point to an intervention that might prevent worsening of the illness. ..
  4. Cannabis and Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2009
    ..A positive finding would help inform current neurodevelopmental models of schizophrenia and point to an intervention that might prevent worsening of the illness. ..
  5. Cannabis and Schizophrenia
    Sanjiv Kumra; Fiscal Year: 2010
    ..A positive finding would help inform current neurodevelopmental models of schizophrenia and point to an intervention that might prevent worsening of the illness. ..