Anand Kumar

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint Cortical thinning in patients with late-life minor depression
    Anand Kumar
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:459-64. 2014
  2. pmc Protein binding in patients with late-life depression
    Anand Kumar
    Department of Psychiatry, University of Illinois at Chicago, USA
    Arch Gen Psychiatry 68:1143-50. 2011
  3. pmc Prefrontal vulnerabilities and whole brain connectivity in aging and depression
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, 1601W Taylor St, MC912, Chicago, IL 60601, USA
    Neuropsychologia 51:1463-70. 2013
  4. pmc Hierarchical structural mapping for globally optimized estimation of functional networks
    Alex D Leow
    Department of Psychiatry, University of Illinois, Chicago, IL, USA
    Med Image Comput Comput Assist Interv 15:228-36. 2012
  5. ncbi request reprint Investigating brain community structure abnormalities in bipolar disorder using path length associated community estimation
    Johnson J GadElkarim
    Electrical and Computer Engineering Department, University of Illinois at Chicago, Chicago, Illinois Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois
    Hum Brain Mapp 35:2253-64. 2014
  6. doi request reprint Preliminary analysis of age of illness onset effects on symptom profiles in major depressive disorder
    Rebecca A Charlton
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA
    Int J Geriatr Psychiatry 28:1166-74. 2013
  7. pmc White matter tract integrity of anterior limb of internal capsule in major depression and type 2 diabetes
    Aifeng Zhang
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL 60612, USA
    Neuropsychopharmacology 38:1451-9. 2013
  8. ncbi request reprint Impaired inter-hemispheric integration in bipolar disorder revealed with brain network analyses
    Alex Leow
    Department of Psychiatry, University of Illinois at Chicago, 1601 West Taylor Street, Chicago, IL 60612, USA
    Biol Psychiatry 73:183-93. 2013
  9. pmc Differential associations between types of verbal memory and prefrontal brain structure in healthy aging and late life depression
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, 1601 West Taylor Street, MC912, Chicago, IL 60612, USA
    Neuropsychologia 50:1823-9. 2012
  10. pmc Quantitative tract-specific measures of uncinate and cingulum in major depression using diffusion tensor imaging
    Aifeng Zhang
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL 60612, USA
    Neuropsychopharmacology 37:959-67. 2012

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Cortical thinning in patients with late-life minor depression
    Anand Kumar
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:459-64. 2014
    ..The purpose of our current study was to examine cortical thickness in a sample of patients with late-life minor depression and non-depressed comparison subjects using magnetic resonance imaging (MRI)...
  2. pmc Protein binding in patients with late-life depression
    Anand Kumar
    Department of Psychiatry, University of Illinois at Chicago, USA
    Arch Gen Psychiatry 68:1143-50. 2011
    ..Depression has been identified as a risk factor and a prodrome of dementia. Common neurobiological mechanisms may underlie this clinical and phenomenologic overlap...
  3. pmc Prefrontal vulnerabilities and whole brain connectivity in aging and depression
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, 1601W Taylor St, MC912, Chicago, IL 60601, USA
    Neuropsychologia 51:1463-70. 2013
    ..It appears that the whole brain impact of specific fronto-limbic vulnerabilities in aging may be eclipsed in the presence of disease-specific neuropathology like that seen in late life depression...
  4. pmc Hierarchical structural mapping for globally optimized estimation of functional networks
    Alex D Leow
    Department of Psychiatry, University of Illinois, Chicago, IL, USA
    Med Image Comput Comput Assist Interv 15:228-36. 2012
    ..Results revealed that BDD subjects under-utilized several key local connections in the visual system, which may help explain previously reported fMRI findings and further elucidate the underlying pathophysiology of BDD...
  5. ncbi request reprint Investigating brain community structure abnormalities in bipolar disorder using path length associated community estimation
    Johnson J GadElkarim
    Electrical and Computer Engineering Department, University of Illinois at Chicago, Chicago, Illinois Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois
    Hum Brain Mapp 35:2253-64. 2014
    ..Results showed community structural differences in posterior default mode network regions, with the bipolar group exhibiting left-right decoupling...
  6. doi request reprint Preliminary analysis of age of illness onset effects on symptom profiles in major depressive disorder
    Rebecca A Charlton
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA
    Int J Geriatr Psychiatry 28:1166-74. 2013
    ..Major depressive disorder (MDD) is prevalent across the lifespan, but relatively little is known about how age of illness onset impacts the cognitive and affective presentation of MDD...
  7. pmc White matter tract integrity of anterior limb of internal capsule in major depression and type 2 diabetes
    Aifeng Zhang
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL 60612, USA
    Neuropsychopharmacology 38:1451-9. 2013
    ..016). Our study demonstrated novel findings of white matter abnormalities of the ALIC in depression and diabetes. These findings have implications for clinical manifestations of depression and diabetes as well as their pathophysiology...
  8. ncbi request reprint Impaired inter-hemispheric integration in bipolar disorder revealed with brain network analyses
    Alex Leow
    Department of Psychiatry, University of Illinois at Chicago, 1601 West Taylor Street, Chicago, IL 60612, USA
    Biol Psychiatry 73:183-93. 2013
    ..However, many inconsistencies remain in the literature, and no study to date has conducted brain network analyses with a graph-theoretic approach...
  9. pmc Differential associations between types of verbal memory and prefrontal brain structure in healthy aging and late life depression
    Melissa Lamar
    Department of Psychiatry, University of Illinois at Chicago, 1601 West Taylor Street, MC912, Chicago, IL 60612, USA
    Neuropsychologia 50:1823-9. 2012
    ..More specifically, it points toward a network of predominantly anterior brain regions that may underlie the executive contribution to list-learning in older adults with depression...
  10. pmc Quantitative tract-specific measures of uncinate and cingulum in major depression using diffusion tensor imaging
    Aifeng Zhang
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL 60612, USA
    Neuropsychopharmacology 37:959-67. 2012
    ..In the MDD group, the severity of depression is associated with reduced NNF in the right UF. These findings have implications for both clinical manifestations of depression as well as its pathophysiology...
  11. pmc Graph theory analysis of cortical-subcortical networks in late-life depression
    Olusola Ajilore
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:195-206. 2014
    ..The purpose of this study was to use interregional correlations of cortical and subcortical volumes to examine cortical-subcortical structural network properties in subjects with LLD compared with healthy comparison subjects...
  12. pmc Mood, cognition and in vivo protein imaging: the emerging nexus in clinical neuroscience
    Anand Kumar
    Department of Psychiatry, the Semel Institute for Neuroscience, University of California, Los Angeles, CA 90024, USA
    Int J Geriatr Psychiatry 23:555-63. 2008
    ..Disorders of mood and cognition overlap in the elderly and there is an emerging consensus that both groups of disorders share neurobiological substrates...
  13. pmc Regional cortical gray matter thickness differences associated with type 2 diabetes and major depression
    Olusola Ajilore
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL, USA
    Psychiatry Res 184:63-70. 2010
    ..Depression and diabetes are associated with significant cortical gray matter thinning in medial prefrontal areas...
  14. pmc Verbal learning and memory in older adults with minor and major depression
    Raquelle I Mesholam-Gately
    Harvard Medical School, Department of Psychiatry, Massachusetts Mental Health Center, Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Arch Clin Neuropsychol 27:196-207. 2012
    ..The findings suggest that depression in the elderly is a heterogeneous entity and that the CVLT may be a useful tool for characterizing learning and memory in late-onset depressive disorders...
  15. pmc Multimodal brain connectivity analysis in unmedicated late-life depression
    Reza Tadayonnejad
    Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 9:e96033. 2014
    ..Coordinated structural and functional impairment in circuits involved in emotion regulation and reward pathways play an important role in the pathophysiology of LLD. ..
  16. pmc Association of brain network efficiency with aging, depression, and cognition
    Olusola Ajilore
    Department of Psychiatry, University of Illinois at Chicago, Chicago, IL Electronic address
    Am J Geriatr Psychiatry 22:102-10. 2014
    ..The purpose of this study was to compare four measures of network efficiency derived from novel techniques for understanding white matter connectivity on their associations with aging, depression, and cognition...
  17. pmc A framework for quantifying node-level community structure group differences in brain connectivity networks
    Johnson J GadElkarim
    Electrical and Computer Engineering Department, University of Illinois at Chicago, USA
    Med Image Comput Comput Assist Interv 15:196-203. 2012
    ..These findings are consistent with those reported in previous literature, suggesting a higher degree of ruminative self-reflections in depression...
  18. pmc Two-dimensional semi-LASER correlation spectroscopy with well-maintained cross peaks
    Meijin Lin
    University of Illinois at Chicago, Department of Psychiatry, Chicago, Illinois, USA
    Magn Reson Med 72:26-32. 2014
    ....
  19. ncbi request reprint Gray matter prefrontal changes in type 2 diabetes detected using MRI
    Anand Kumar
    Department of Psychiatry, Semel Institute for Neuroscience, University of California, Los Angeles, Los Angeles, California, USA
    J Magn Reson Imaging 27:14-9. 2008
    ..To examine the volumes of the gray and white matter both globally and regionally in patients diagnosed with type 2 diabetes and controls...

Research Grants15

  1. Cerebrovascular Basis of Depression in Diabetes-NIDDM
    Anand Kumar; Fiscal Year: 2002
    ..We will integrate the biological and behavioral measures and elucidate their collective contributions to the pathophysiology of clinically significant depression. ..
  2. Cerebrovascular Basis of Depression in Diabetes-NIDDM
    Anand Kumar; Fiscal Year: 2005
    ..We will integrate the biological and behavioral measures and elucidate their collective contributions to the pathophysiology of clinically significant depression. ..
  3. MINOR DEPRESSION--CLINICAL AND BIOLOGICAL SUBSTRATES
    Anand Kumar; Fiscal Year: 2000
    ..The relationship between specific neuroanatomical measures and relevant clinical indicators of disease burden will be studies and their relative contributions to late onset minor depression ascertained. ..
  4. Cortical/Subcortical Circuits in Late-Life Depression
    Anand Kumar; Fiscal Year: 2009
    ..The role of the frontal white matter and subcortical nuclei in the etiology of late-life MDD has received scant attention and the proposed studies will help us elucidate the mechanisms and pathways that lead to MDD in late-life. ..
  5. Myelin Glia and Depression in Type 2 Diabetes
    Anand Kumar; Fiscal Year: 2010
    ....
  6. Cortical/Subcortical Circuits in Late-Life Depression
    Anand Kumar; Fiscal Year: 2006
    ..The role of the frontal white matter and subcortical nuclei in the etiology of late-life MDD has received scant attention and the proposed studies will help us elucidate the mechanisms and pathways that lead to MDD in late-life. ..
  7. Cerebrovascular Basis of Depression in Diabetes-NIDDM
    Anand Kumar; Fiscal Year: 2004
    ..We will integrate the biological and behavioral measures and elucidate their collective contributions to the pathophysiology of clinically significant depression. ..
  8. MINOR DEPRESSION--CLINICAL AND BIOLOGICAL SUBSTRATES
    Anand Kumar; Fiscal Year: 2004
    ..The relationship between specific neuroanatomical measures and relevant clinical indicators of disease burden will be studies and their relative contributions to late onset minor depression ascertained. ..
  9. MINOR DEPRESSION--CLINICAL AND BIOLOGICAL SUBSTRATES
    Anand Kumar; Fiscal Year: 2003
    ..The relationship between specific neuroanatomical measures and relevant clinical indicators of disease burden will be studies and their relative contributions to late onset minor depression ascertained. ..
  10. Cerebrovascular Basis of Depression in Diabetes-NIDDM
    Anand Kumar; Fiscal Year: 2003
    ..We will integrate the biological and behavioral measures and elucidate their collective contributions to the pathophysiology of clinically significant depression. ..
  11. MINOR DEPRESSION--CLINICAL AND BIOLOGICAL SUBSTRATES
    Anand Kumar; Fiscal Year: 2002
    ..The relationship between specific neuroanatomical measures and relevant clinical indicators of disease burden will be studies and their relative contributions to late onset minor depression ascertained. ..
  12. Cortical/Subcortical Circuits in Late-Life Depression
    Anand Kumar; Fiscal Year: 2010
    ..The role of the frontal white matter and subcortical nuclei in the etiology of late-life MDD has received scant attention and the proposed studies will help us elucidate the mechanisms and pathways that lead to MDD in late-life. ..
  13. Cerebrovascular Basis of Depression in Diabetes-NIDDM
    Anand Kumar; Fiscal Year: 2004
    ..We will integrate the biological and behavioral measures and elucidate their collective contributions to the pathophysiology of clinically significant depression. ..
  14. MINOR DEPRESSION--CLINICAL AND BIOLOGICAL SUBSTRATES
    Anand Kumar; Fiscal Year: 2001
    ..The relationship between specific neuroanatomical measures and relevant clinical indicators of disease burden will be studies and their relative contributions to late onset minor depression ascertained. ..