Walter A Kukull

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Dementia and Alzheimer disease incidence: a prospective cohort study
    Walter A Kukull
    National Alzheimer Coordinating Center, Department of Epidemiology, Box 357236, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195 7236, USA
    Arch Neurol 59:1737-46. 2002
  2. pmc Generalizability: the trees, the forest, and the low-hanging fruit
    Walter A Kukull
    Department of Epidemiology, University of Washington School of Public Health, Seattle, USA
    Neurology 78:1886-91. 2012
  3. ncbi request reprint Dementia epidemiology
    Walter A Kukull
    Department of Epidemiology, University of Washington, Box 357236, Seattle, WA 98195 7286, USA
    Med Clin North Am 86:573-90. 2002
  4. pmc Age-varying association between statin use and incident Alzheimer's disease
    Ge Li
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    J Am Geriatr Soc 58:1311-7. 2010
  5. ncbi request reprint Biomechanical properties of shoes and risk of falls in older adults
    Allan F Tencer
    Harborview Injury Prevention and Research Center, Orthopedic Sciences Laboratory, Harborview Medical Center, MS 359798, 325 Ninth Avenue, Seattle, WA 98104, USA
    J Am Geriatr Soc 52:1840-6. 2004
  6. pmc Differences in rate of functional decline across three dementia types
    Dawn P Gill
    Aging, Rehabilitation and Geriatric Care Research Centre, Lawson Health Research Institute, London, Ontario, Canada National Alzheimer s Coordinating Center, University of Washington, Seattle, WA, USA Department of Epidemiology, University of Washington, Seattle, WA, USA Electronic address
    Alzheimers Dement 9:S63-71. 2013
  7. pmc Calcium channel blockers and beta-blockers in relation to Parkinson's disease
    Thanh G N Ton
    Department of Epidemiology, University of Washington, Box 357236, Seattle, WA 98195 7326, USA
    Parkinsonism Relat Disord 13:165-9. 2007
  8. pmc Cognitive impairment in older adults without dementia: clinical and pathologic outcomes in a community-based sample
    Lucy Y Wang
    Mental Illness Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, USA
    J Geriatr Psychiatry Neurol 22:256-65. 2009
  9. ncbi request reprint Subjective memory deterioration and future dementia in people aged 65 and older
    Li Wang
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Am Geriatr Soc 52:2045-51. 2004
  10. ncbi request reprint Interrater reliability and accuracy in identifying ischemic strokes using computed tomography scans in people with dementia
    James D Bowen
    Department of Neurology, University of Washington, Seattle, Washington 98195, USA
    J Am Geriatr Soc 53:1743-7. 2005

Detail Information

Publications36

  1. ncbi request reprint Dementia and Alzheimer disease incidence: a prospective cohort study
    Walter A Kukull
    National Alzheimer Coordinating Center, Department of Epidemiology, Box 357236, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195 7236, USA
    Arch Neurol 59:1737-46. 2002
    ..Incidence estimates for the United States are few and vary with the population sampled and study design; we present data that will contribute to a consensus of these rates...
  2. pmc Generalizability: the trees, the forest, and the low-hanging fruit
    Walter A Kukull
    Department of Epidemiology, University of Washington School of Public Health, Seattle, USA
    Neurology 78:1886-91. 2012
    ..They also lay out relevant practical issues in study design, from sample selection to assessment of exposures, in both clinic-based and population-based settings...
  3. ncbi request reprint Dementia epidemiology
    Walter A Kukull
    Department of Epidemiology, University of Washington, Box 357236, Seattle, WA 98195 7286, USA
    Med Clin North Am 86:573-90. 2002
    ..The tasks of public health and epidemiology should still involve prevention, the nonrandom occurrence of disease, and its environmental context in addition to heredity. The tools to address these tasks should continue to be refined...
  4. pmc Age-varying association between statin use and incident Alzheimer's disease
    Ge Li
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    J Am Geriatr Soc 58:1311-7. 2010
    ..To determine whether risk reduction of statins for Alzheimer's disease (AD) varies by age or presence of apolipoprotein E (APOE) epsilon4 allele...
  5. ncbi request reprint Biomechanical properties of shoes and risk of falls in older adults
    Allan F Tencer
    Harborview Injury Prevention and Research Center, Orthopedic Sciences Laboratory, Harborview Medical Center, MS 359798, 325 Ninth Avenue, Seattle, WA 98104, USA
    J Am Geriatr Soc 52:1840-6. 2004
    ..To determine the relationships between the biomechanical properties of shoes worn in a cohort of healthy older adults and the risk of falling...
  6. pmc Differences in rate of functional decline across three dementia types
    Dawn P Gill
    Aging, Rehabilitation and Geriatric Care Research Centre, Lawson Health Research Institute, London, Ontario, Canada National Alzheimer s Coordinating Center, University of Washington, Seattle, WA, USA Department of Epidemiology, University of Washington, Seattle, WA, USA Electronic address
    Alzheimers Dement 9:S63-71. 2013
    ..The purpose of this study was to estimate differences in rates of functional decline in Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and vascular dementia (VaD) and whether differences vary by age or sex...
  7. pmc Calcium channel blockers and beta-blockers in relation to Parkinson's disease
    Thanh G N Ton
    Department of Epidemiology, University of Washington, Box 357236, Seattle, WA 98195 7326, USA
    Parkinsonism Relat Disord 13:165-9. 2007
    ..The weakness of these associations and the absence of additional influence of dose or duration of use argue against any causal interpretation...
  8. pmc Cognitive impairment in older adults without dementia: clinical and pathologic outcomes in a community-based sample
    Lucy Y Wang
    Mental Illness Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, USA
    J Geriatr Psychiatry Neurol 22:256-65. 2009
    ..4 +/- 2.1 vs 3.1 +/- 2.7, P = .02). These observations are consistent with the view that nondemented patients with underlying AD may be more likely to present with memory than nonmemory cognitive impairment...
  9. ncbi request reprint Subjective memory deterioration and future dementia in people aged 65 and older
    Li Wang
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Am Geriatr Soc 52:2045-51. 2004
    ..To study whether subjective memory deterioration is associated with future dementia in older people...
  10. ncbi request reprint Interrater reliability and accuracy in identifying ischemic strokes using computed tomography scans in people with dementia
    James D Bowen
    Department of Neurology, University of Washington, Seattle, Washington 98195, USA
    J Am Geriatr Soc 53:1743-7. 2005
    ..To assess the reliability and interobserver agreement of stroke identification on neuroimaging in patients presenting with dementia...
  11. ncbi request reprint Alcohol, gender, and cognitive performance: a longitudinal study comparing older Japanese and non-Hispanic white Americans
    Gail E Bond
    University of Washington, Psychosocial and Community Health, Box 357263, Seattle, WA 98195 7263, USA
    J Aging Health 16:615-40. 2004
    ..Background: Recent data demonstrate that moderate consumption of alcohol may be beneficial to cognition...
  12. ncbi request reprint Tumor necrosis factor alpha and interleukin 10 promoter region polymorphisms and risk of late-onset Alzheimer disease
    Erin M Ramos
    Institute for Public Health Genetics, Department of Medicine, University of Washington, Seattle, WA, USA
    Arch Neurol 63:1165-9. 2006
    ..Functional polymorphisms in tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10) can affect immune response, inflammation, tissue injury, and possibly the susceptibility to Alzheimer disease (AD)...
  13. ncbi request reprint Survival after initial diagnosis of Alzheimer disease
    Eric B Larson
    University of Washington and the Group Health Cooperative, Seattle, Washington, USA
    Ann Intern Med 140:501-9. 2004
    ..Alzheimer disease is an increasingly common condition in older people. Knowledge of life expectancy after the diagnosis of Alzheimer disease and of associations of patient characteristics with survival may help planning for future care...
  14. ncbi request reprint Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study
    James B Leverenz
    Veterans Affairs Northwest Network Mental Illness Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, 116 MIRECC, Seattle, WA 98108, USA
    Arch Neurol 59:1099-106. 2002
    ..However, these studies were from selected samples and therefore are not necessarily representative of patients seen in the general medical community...
  15. ncbi request reprint Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial
    Linda Teri
    Department of Psychosocial and Community Health, University of Washington, Seattle 98195, USA
    JAMA 290:2015-22. 2003
    ..Exercise training for patients with Alzheimer disease combined with teaching caregivers how to manage behavioral problems may help decrease the frailty and behavioral impairment that are often prevalent in patients with Alzheimer disease...
  16. ncbi request reprint The National Alzheimer's Coordinating Center (NACC) database: the Uniform Data Set
    Duane L Beekly
    Department of Epidemiology, National Alzheimer s Coordinating Center, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98105, USA
    Alzheimer Dis Assoc Disord 21:249-58. 2007
    ..Thus, the NACC web site (https://www.alz.washington.edu) was enhanced to provide efficient and secure access data submission and retrieval systems...
  17. ncbi request reprint Age-varying association between blood pressure and risk of dementia in those aged 65 and older: a community-based prospective cohort study
    Ge Li
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA
    J Am Geriatr Soc 55:1161-7. 2007
    ..To assess variation in the association between blood pressure (BP) and risk for dementia across a spectrum of older ages and to examine BP changes before dementia onset...
  18. pmc Risk of decline in functional activities in dementia with Lewy bodies and Alzheimer disease
    Dawn P Gill
    National Alzheimer s Coordinating Center, Department of Epidemiology, University of Washington, Seattle, WA 98105, USA
    Alzheimer Dis Assoc Disord 25:17-23. 2011
    ..These findings may provide anticipatory guidance to families and healthcare providers, which may be useful in the planning of care strategies...
  19. pmc Associations between microinfarcts and other macroscopic vascular findings on neuropathologic examination in 2 databases
    W T Longstreth
    Department of Neurology, University of Washington, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104 2420, USA
    Alzheimer Dis Assoc Disord 23:291-4. 2009
    ..9, 95% CI: 1.4, 6.3). These neuropathologic associations suggest that people whose cranial MRI shows macroinfarcts, hemorrhages, or leukoencephalopathy are more likely also to have microinfarcts...
  20. ncbi request reprint Mitochondrial genetic variants and Alzheimer disease: a case-control study of the T4336C and G5460A variants
    Steven D Edland
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Alzheimer Dis Assoc Disord 16:1-7. 2002
    ..Substantially larger samples than are currently available would be required to resolve this question. G5460(A/T) variants were also investigated and found not to be associated with Alzheimer disease...
  21. ncbi request reprint Older adults and functional decline: a cross-cultural comparison
    Susan M McCurry
    Department of Psychosocial and Community Health, University of Washington, Seattle 98115 2053, USA
    Int Psychogeriatr 14:161-79. 2002
    ....
  22. ncbi request reprint Nonsteroidal anti-inflammatory drugs and risk of Parkinson's disease
    Thanh G Ton
    Department of Epidemiology, University of Washington, Seattle, Washington 98195, USA
    Mov Disord 21:964-9. 2006
    ..Our results provide only limited support for the hypothesis that use of aspirin may reduce the risk of this disease, and no indication of protection from other NSAIDs...
  23. pmc Comparing measures of decline to dementia in amnestic MCI subjects in the National Alzheimer's Coordinating Center (NACC) Uniform Data Set
    Sarah E Monsell
    National Alzheimer s Coordinating Center, University of Washington, Seattle, Washington 98105, USA
    Int Psychogeriatr 24:1553-60. 2012
    ....
  24. ncbi request reprint Footwear style and risk of falls in older adults
    Thomas D Koepsell
    Department of Epidemiology, University of Washington, Seattle 98195, USA
    J Am Geriatr Soc 52:1495-501. 2004
    ..To determine how the risk of a fall in an older adult varies in relation to style of footwear worn...
  25. ncbi request reprint Active and passive cigarette smoking and risk of intracranial meningioma
    Leslie E Phillips
    Department of Neurology, School of Public Health and Community Medicine, University of Washington, Seattle, Wash, USA
    Neuroepidemiology 24:117-22. 2005
    ..0; 95% CI 1.1-3.5), and risk increased with increasing duration of exposure (p for trend = 0.02). Uncertain is whether these findings reflect a true biological phenomenon or result from chance or uncontrolled confounding...
  26. doi request reprint Conjugal Alzheimer disease: risk in children when both parents have Alzheimer disease
    Suman Jayadev
    Department of Neurology, University of Washington, Seattle, USA
    Arch Neurol 65:373-8. 2008
    ..There is limited information regarding children's risk of Alzheimer disease (AD) if both parents are affected...
  27. pmc Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient
    James B Leverenz
    Department of Veterans Affairs Northwest Network Mental Illness and Parkinson s Disease Research, University of Washington, Seattle, WA 98108, USA
    Brain Pathol 18:220-4. 2008
    ..In addition, this modification allows for more limited sampling of brain regions for classification of LRP. We propose that these modified criteria for the categorization of LRP be utilized in patients with a history of dementia...
  28. pmc Clinical and pathologic presentation in Parkinson's disease by apolipoprotein e4 allele status
    Sarah E Monsell
    National Alzheimer s Coordinating Center, University of Washington, Seattle, WA 98105, USA Electronic address
    Parkinsonism Relat Disord 20:503-7. 2014
    ..In this analysis we explored potential significant associations between APOE e4 allele status and characteristics of clinical presentation in patients with PD...
  29. ncbi request reprint The National Alzheimer's Coordinating Center (NACC) Database: an Alzheimer disease database
    Duane L Beekly
    National Alzheimer s Coordinating Center, Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98105, USA
    Alzheimer Dis Assoc Disord 18:270-7. 2004
    ..NACC also designed a data management system to easily collect and manage these data. The NACC web site (www.alz.washington.edu) was created to allow access to the data...
  30. pmc Hippocampal Sclerosis of Aging is a Key Alzheimer's Disease Mimic: Clinical-Pathologic Correlations and Comparisons with both Alzheimer's Disease and Non-Tauopathic Frontotemporal Lobar Degeneration
    Willa D Brenowitz
    National Alzheimer s Coordinating Center NACC, University of Washington, Seattle, WA, USA Department of Epidemiology, University of Washington, Seattle, WA, USA
    J Alzheimers Dis 39:691-702. 2014
    ..We conclude that the manifestations of HS-Aging, increasingly recognized in recent years, probably indicate a separate disease process of direct relevance to patient care, dementia research, and clinical trials. ..
  31. ncbi request reprint The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers
    John C Morris
    Washington University, St Louis, MO 63108, USA
    Alzheimer Dis Assoc Disord 20:210-6. 2006
    ..Data obtained with the UDS are submitted to the National Alzheimer's Coordinating Center and represent a unique and valuable source of data to support and stimulate collaborative research...
  32. ncbi request reprint Depression as a risk factor for Alzheimer disease: the MIRAGE Study
    Robert C Green
    Department of Neurology, Genetics Program, Boston University School of Medicine, MA 02118, USA
    Arch Neurol 60:753-9. 2003
    ..Depression symptoms may be associated with the development of Alzheimer disease (AD)...
  33. ncbi request reprint Perspectives on shared genetic contributions for Parkinson disease and Alzheimer disease
    Walter A Kukull
    Arch Neurol 61:1007-8. 2004
  34. pmc Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain
    Winnie S Liang
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA
    Physiol Genomics 28:311-22. 2007
    ..These neuronal profiles will provide valuable reference information for future studies of the brain, in normal aging, AD and other neurological and psychiatric disorders...
  35. ncbi request reprint The growing global burden of dementia
    Walter A Kukull
    Lancet Neurol 5:199-200. 2006
  36. pmc Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set
    Winnie S Liang
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA
    Physiol Genomics 33:240-56. 2008
    ..We provide this carefully phenotyped, laser capture microdissected intraindividual brain region expression data set to the community as a public resource...