Heather C Kuiper

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress
    Heather C Kuiper
    Linus Pauling Institute and the Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon, USA
    Curr Protoc Toxicol . 2011
  2. pmc Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans
    Heather C Kuiper
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Free Radic Biol Med 50:848-53. 2011
  3. pmc Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study
    Heather C Kuiper
    Linus Pauling Institute and the Department of Pharmaceutical Sciences, Oregon State University, Corvallis, OR 97331, USA
    Free Radic Biol Med 48:65-72. 2010
  4. pmc Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress
    Heather C Kuiper
    Department of Pharmaceutical Sciences and the Linus Pauling Institute, Oregon State University, Corvallis Oregon 97331, USA
    J Biol Chem 283:17131-8. 2008
  5. pmc Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells
    Cristobal L Miranda
    Linus Pauling Institute and the Departments of Pharmaceutical Sciences and Statistics, Oregon State University, Corvallis, Oregon 97331, USA
    Chem Res Toxicol 22:863-74. 2009

Collaborators

Detail Information

Publications5

  1. pmc LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress
    Heather C Kuiper
    Linus Pauling Institute and the Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon, USA
    Curr Protoc Toxicol . 2011
    ..Included are protocols for preparation of labeled LPO-MA conjugates from unlabeled LPO products and deuterium labeled MA...
  2. pmc Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans
    Heather C Kuiper
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Free Radic Biol Med 50:848-53. 2011
    ..0092) urinary total of metabolites by ~20%. Thus, HPNE metabolites can be reduced favorably in response to improved plasma ascorbic acid concentrations, an effect due to ascorbic acid antioxidant function...
  3. pmc Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study
    Heather C Kuiper
    Linus Pauling Institute and the Department of Pharmaceutical Sciences, Oregon State University, Corvallis, OR 97331, USA
    Free Radic Biol Med 48:65-72. 2010
    ..We were able to show significant decreases in HNE-MA, DHN-MA, and total LPO-MA in a group of seven smokers upon smoking cessation. These data demonstrate the value of HNE and ONE metabolites as in vivo markers of oxidative stress...
  4. pmc Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress
    Heather C Kuiper
    Department of Pharmaceutical Sciences and the Linus Pauling Institute, Oregon State University, Corvallis Oregon 97331, USA
    J Biol Chem 283:17131-8. 2008
    ..Our data suggest that conjugates of HNE and ONE metabolites have value as markers of in vivo oxidative stress and lipid peroxidation...
  5. pmc Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells
    Cristobal L Miranda
    Linus Pauling Institute and the Departments of Pharmaceutical Sciences and Statistics, Oregon State University, Corvallis, Oregon 97331, USA
    Chem Res Toxicol 22:863-74. 2009
    ..The formation of ascorbate adducts of HNE was observed in the cell exposure experiments, but it represented a minor pathway contributing to the elimination of HNE and to the protective effects of ascorbate...