Research Topics
| Mary K KuhnerSummaryAffiliation: University of Washington Country: USA Publications
| Collaborators |
Detail Information
Publications
Comparing likelihood and Bayesian coalescent estimation of population parametersMary K Kuhner
Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA
Genetics 175:155-65. 2007..However, the Bayesian approach rejected the generative parameter values significantly less often than the likelihood approach, both in cases where the level of rejection was normal and in cases where it was too high...
Robustness of coalescent estimators to between-lineage mutation rate variationMary K Kuhner
Department of Genome Sciences, University of Washington, Seattle, WA, USA
Mol Biol Evol 23:2355-60. 2006..Both estimators are robust to modest rate variation; however, their use should be coupled with a statistical test to rule out extreme rate variation as the resulting CIs may not be reliable...
The limits of fine-scale mappingLucian P Smith
Department of Genome Sciences, University of Washington, Seattle, WA 98195 5065, USA
Genet Epidemiol 33:344-56. 2009..If haplotypes are unknown due to incomplete penetrance, much information is lost, with more information lost the less indicative phenotype is of the underlying genotype...
LAMARC 2.0: maximum likelihood and Bayesian estimation of population parametersMary K Kuhner
Department of Genome Sciences Box 357730 University of Washington Seattle, 98195 7730, USA
Bioinformatics 22:768-70. 2006..It is available as portable source code and executables for all three major platforms. AVAILABILITY: LAMARC 2.0 is freely available at http://evolution.gs.washington.edu/lamarc..
Coalescent genealogy samplers: windows into population historyMary K Kuhner
Department of Genome Sciences, University of Washington, Seattle, WA 98195 5065, USA
Trends Ecol Evol 24:86-93. 2009..This review summarizes available genealogy-sampler software, including data requirements and limitations on the use of each program...
